RESUMEN
We report a new case of polyostotic fibrous dysplasia (FD). A 26-year-old woman was referred to our department complaining of pain in her left arm. She had suffered for tow fractures in left leg and arm previously. Plain radiographs showed osteolytics lesions at the left humerus and radius. Histological examination of the surgical specimens showed FD. She has beneficed with zoledronic acid perfusion.
Asunto(s)
Displasia Fibrosa Poliostótica/diagnóstico por imagen , Húmero/diagnóstico por imagen , Radio (Anatomía)/diagnóstico por imagen , Adulto , Conservadores de la Densidad Ósea/uso terapéutico , Difosfonatos/uso terapéutico , Femenino , Displasia Fibrosa Poliostótica/tratamiento farmacológico , Displasia Fibrosa Poliostótica/patología , Humanos , Húmero/patología , Imidazoles/uso terapéutico , Radiografía , Radio (Anatomía)/patología , Ácido ZoledrónicoRESUMEN
A 27-year-old-man was diagnosed as having ankylosing spondylitis (AS) in 2003 and received a treatment by etanercept. Typical symptoms of active Crohn's disease (CD) developed 11 months after initiation of etanercept therapy. At colonoscopy, lesions compatible with CD were found endoscopically and histologically. Etanercept was interrupted and CD responded to standard treatment. A switch to infliximab was decided to treat a flare up ofAS. New onset CD may be considered an immune mediated injury induced by etanercept, but the causative role of the latter has not been demonstrated at this stage.
Asunto(s)
Enfermedad de Crohn/inducido químicamente , Inmunoglobulina G/efectos adversos , Factores Inmunológicos/efectos adversos , Adulto , Anticuerpos Monoclonales/uso terapéutico , Colonoscopía , Etanercept , Humanos , Inmunoglobulina G/uso terapéutico , Factores Inmunológicos/uso terapéutico , Infliximab , Masculino , Receptores del Factor de Necrosis Tumoral/uso terapéutico , Espondilitis Anquilosante/tratamiento farmacológicoRESUMEN
The purpose of this report is to describe the case of a 13-year-old boy presenting typical sciatica leading to the discovery of primary pelvic hydatid cyst extending to the ischiatic bone. Diagnosis was suspected based on echography and magnetic resonance imaging and confirmed by surgical exploration.
Asunto(s)
Equinococosis/complicaciones , Ciática/parasitología , Adolescente , Humanos , Masculino , Pelvis , TúnezRESUMEN
Tabetic arthropathy (TA) is a type of neuropathic arthropathy that has become rare. The purpose of this report is to describe a case of tabetic arthropathy involving the knee. A 53-year-old man was hospitalized for painless right knee arthropathy. Clinical examination demonstrated hydarthrosis of the right knee, peripheral neuropathic syndrome of the lower limbs, and paralysis of the IXth and Xth cranial pairs. Plain radiography showed the presence of lytic lesions in the internal femoral condyle and tibial plateau. Syphilitic serology tests were positive in the blood and cerebrospinal fluid.
Asunto(s)
Artropatía Neurógena/diagnóstico , Tabes Dorsal/diagnóstico , Artropatía Neurógena/microbiología , Humanos , Articulación de la Rodilla/patología , Masculino , Persona de Mediana Edad , Tabes Dorsal/complicaciones , TúnezAsunto(s)
Lupus Eritematoso Sistémico/complicaciones , Espondilitis Anquilosante/complicaciones , Adulto , Artralgia/etiología , Femenino , Predisposición Genética a la Enfermedad , Humanos , Lupus Eritematoso Sistémico/tratamiento farmacológico , Lupus Eritematoso Sistémico/genética , Articulación Sacroiliaca/patología , Espondilitis Anquilosante/tratamiento farmacológico , Espondilitis Anquilosante/genética , Resultado del TratamientoAsunto(s)
Eosinofilia/etiología , Fascitis/etiología , Lupus Eritematoso Sistémico/complicaciones , Femenino , Glucocorticoides/administración & dosificación , Glucocorticoides/uso terapéutico , Humanos , Lupus Eritematoso Sistémico/fisiopatología , Prednisona/administración & dosificación , Prednisona/uso terapéutico , Síndrome , Adulto JovenAsunto(s)
Artritis Reumatoide/metabolismo , Proteína Ligando Fas/metabolismo , Osteoartritis de la Rodilla/metabolismo , Líquido Sinovial/metabolismo , Receptor fas/metabolismo , Anciano , Apoptosis/inmunología , Artritis Reumatoide/etiología , Artritis Reumatoide/patología , Biomarcadores/metabolismo , Estudios de Casos y Controles , Femenino , Humanos , Masculino , Persona de Mediana Edad , Osteoartritis de la Rodilla/etiología , Osteoartritis de la Rodilla/patología , Membrana Sinovial/metabolismo , Membrana Sinovial/patología , TúnezRESUMEN
Sweet's syndrome (SS) is an acute neutrophilic dermatosis characterised by abrupt onset of fever, leukocytosis and cutaneous eruption, with dermal neutrophilia on skin biopsy. Most cases are idiopathic but SS can be associated with various affections, especially neoplastic, inflammatory and infectious diseases. The authors report the case of an SS occurring in a patient with a known rheumatoid arthritis associated with a secondary Sjögren's syndrome, with incidental finding of concurrent lymph node tuberculosis. In case of SS, an associated disease (malignant, inflammatory or infectious diseases) must imperatively be searched for, knowing that two or more of these affections can coexist.
Asunto(s)
Artritis Reumatoide/complicaciones , Síndrome de Sjögren/complicaciones , Síndrome de Sweet/etiología , Tuberculosis Ganglionar/complicaciones , Adulto , Femenino , HumanosRESUMEN
Hydatidosis, also known as echinococcosis, is a rare but serious parasitic disease in endemic areas. Primary spinal location is extremely rare. This case report describes a rare instance of hydatid cyst that caused severe and progressive low-back pain and neurologic dysfunction. Spine MRI showed a unique vertebral collapse of Th12 body with multicystic lesions filling the spinal canal. In addition, hydatidosis serodiagnostic test was positive at 1/725. Treatment depended on the actual surgical removal of the cysts. Surgery consisted in excision and extirpation of the cysts, associated with decompressive laminectomy. The diagnosis was confirmed on the basis of histological results. No coincidental hydatid visceral involvement was found. Antihelminthic drugs (Albendazole) were promptly given before surgery for a long period. The outcome was satisfactorily marked by total regression of the motor deficit and sphincter disorders.
Asunto(s)
Equinococosis/diagnóstico , Fracturas por Compresión/etiología , Dolor de la Región Lumbar/etiología , Fracturas de la Columna Vertebral/etiología , Vértebras Torácicas/lesiones , Equinococosis/complicaciones , Fracturas por Compresión/diagnóstico , Humanos , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Fracturas de la Columna Vertebral/diagnósticoRESUMEN
Brucellosis is a zoonosis that affects several organs. The spine is the most common site of musculoskeletal involvement. However, multiple-level spinal involvement is rare in brucella spondylodiscitis. The authors report a case of a 56-year-old male shepherd who had developed a spondylodiscitis affecting simultaneously the cervical, thoracic and lumbar regions. The diagnosis was established by using MRI after the brucella-agglutination test was found to be positive. A high degree of suspicion in the diagnosis of brucellar spondylodiscitis is essential to reduce the delay for the treatment. Thus, it should be essentially included in the differential diagnosis of longstanding cervical, thoracic or back pain, particularly in regions where brucellosis is endemic. Screening serological tests for brucella should be used more widely in cases with low index of suspicion, especially in endemic areas.
Asunto(s)
Brucelosis/diagnóstico , Vértebras Cervicales , Discitis/microbiología , Vértebras Lumbares , Imagen por Resonancia Magnética , Vértebras Torácicas , Brucelosis/complicaciones , Discitis/diagnóstico , Humanos , Masculino , Persona de Mediana EdadRESUMEN
Spinal fractures in patients with ankylosing spondylitis may be the result of minor trauma. These fractures may lead to severe neurological deficits, and they are difficult to detect using standard radiography. Often, CT-scans and MRI are required for diagnosis.