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1.

FoxO1-GAB1 axis regulates homing capacity and tonic AKT activity in chronic lymphocytic leukemia.

Seda, Vaclav; Vojackova, Eva; Ondrisova, Laura; Kostalova, Lenka; Sharma, Sonali; Loja, Tomas; Mladonicka Pavlasova, Gabriela; Zicha, Daniel; Kudlickova Peskova, Marie; Krivanek, Jan; Liskova, Kvetoslava; Kren, Leos; Benes, Vladimir; Musilova Litzmanova, Katerina; Borsky, Marek; Oppelt, Jan; Verner, Jan; Pospisilova, Sarka; Brychtova, Yvona; Panovska, Anna; Tan, Zhi; Zhang, Shuxing; Doubek, Michael; Amruz Cerna, Katerina; Mayer, Jiri; Mraz, Marek.

Blood; 138(9): 758-772, 2021 09 02.

Artículo en Inglés | MEDLINE | ID: mdl-33786575

2.

miR-29 modulates CD40 signaling in chronic lymphocytic leukemia by targeting TRAF4: an axis affected by BCR inhibitors.

Sharma, Sonali; Pavlasova, Gabriela Mladonicka; Seda, Vaclav; Cerna, Katerina Amruz; Vojackova, Eva; Filip, Daniel; Ondrisova, Laura; Sandova, Veronika; Kostalova, Lenka; Zeni, Pedro F; Borsky, Marek; Oppelt, Jan; Liskova, Kvetoslava; Kren, Leos; Janikova, Andrea; Pospisilova, Sarka; Fernandes, Stacey M; Shehata, Medhat; Rassenti, Laura Z; Jaeger, Ulrich; Doubek, Michael; Davids, Matthew S; Brown, Jennifer R; Mayer, Jiri; Kipps, Thomas J; Mraz, Marek.

Blood; 137(18): 2481-2494, 2021 05 06.

Artículo en Inglés | MEDLINE | ID: mdl-33171493

3.

LncRNAs in adaptive immunity: role in physiological and pathological conditions.

Zeni, Pedro Faria; Mraz, Marek.

RNA Biol; 18(5): 619-632, 2021 05.

Artículo en Inglés | MEDLINE | ID: mdl-33094664

4.

5'-UTR mRNA splicing determines CD20 levels.

Mraz, Marek.

Blood; 142(20): 1676-1678, 2023 11 16.

Artículo en Inglés | MEDLINE | ID: mdl-37971763

5.

miR-150 downregulation contributes to the high-grade transformation of follicular lymphoma by upregulating FOXP1 levels.

Musilova, Katerina; Devan, Jan; Cerna, Katerina; Seda, Vaclav; Pavlasova, Gabriela; Sharma, Sonali; Oppelt, Jan; Pytlik, Robert; Prochazka, Vit; Prouzova, Zuzana; Trbusek, Martin; Zlamalikova, Lenka; Liskova, Kvetoslava; Kruzova, Lenka; Jarosova, Marie; Mareckova, Andrea; Kornauth, Christoph; Simonitsch-Klupp, Ingrid; Schiefer, Ana-Iris; Merkel, Olaf; Mocikova, Heidi; Burda, Pavel; Machova Polakova, Katerina; Kren, Leos; Mayer, Jiri; Zent, Clive S; Trneny, Marek; Evans, Andrew G; Janikova, Andrea; Mraz, Marek.

Blood; 132(22): 2389-2400, 2018 11 29.

Artículo en Inglés | MEDLINE | ID: mdl-30213873

6.

The regulation and function of CD20: an "enigma" of B-cell biology and targeted therapy.

Pavlasova, Gabriela; Mraz, Marek.

Haematologica; 105(6): 1494-1506, 2020 06.

Artículo en Inglés | MEDLINE | ID: mdl-32482755

7.

Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells.

Boudny, Miroslav; Zemanova, Jana; Khirsariya, Prashant; Borsky, Marek; Verner, Jan; Cerna, Jana; Oltova, Alexandra; Seda, Vaclav; Mraz, Marek; Jaros, Josef; Jaskova, Zuzana; Spunarova, Michaela; Brychtova, Yvona; Soucek, Karel; Drapela, Stanislav; Kasparkova, Marie; Mayer, Jiri; Paruch, Kamil; Trbusek, Martin.

Haematologica; 104(12): 2443-2455, 2019 12.

Artículo en Inglés | MEDLINE | ID: mdl-30975914

8.

Ibrutinib inhibits CD20 upregulation on CLL B cells mediated by the CXCR4/SDF-1 axis.

Pavlasova, Gabriela; Borsky, Marek; Seda, Vaclav; Cerna, Katerina; Osickova, Jitka; Doubek, Michael; Mayer, Jiri; Calogero, Raffaele; Trbusek, Martin; Pospisilova, Sarka; Davids, Matthew S; Kipps, Thomas J; Brown, Jennifer R; Mraz, Marek.

Blood; 128(12): 1609-13, 2016 09 22.

Artículo en Inglés | MEDLINE | ID: mdl-27480113

9.

MicroRNA and mesial temporal lobe epilepsy with hippocampal sclerosis: Whole miRNome profiling of human hippocampus.

Bencurova, Petra; Baloun, Jiri; Musilova, Katerina; Radova, Lenka; Tichy, Boris; Pail, Martin; Zeman, Martin; Brichtova, Eva; Hermanova, Marketa; Pospisilova, Sarka; Mraz, Marek; Brazdil, Milan.

Epilepsia; 58(10): 1782-1793, 2017 10.

Artículo en Inglés | MEDLINE | ID: mdl-28815576

10.

miR-150 influences B-cell receptor signaling in chronic lymphocytic leukemia by regulating expression of GAB1 and FOXP1.

Mraz, Marek; Chen, Liguang; Rassenti, Laura Z; Ghia, Emanuela M; Li, Hongying; Jepsen, Kristen; Smith, Erin N; Messer, Karen; Frazer, Kelly A; Kipps, Thomas J.

Blood; 124(1): 84-95, 2014 Jul 03.

Artículo en Inglés | MEDLINE | ID: mdl-24787006

11.

MicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia.

Cui, Bing; Chen, Liguang; Zhang, Suping; Mraz, Marek; Fecteau, Jessie-F; Yu, Jian; Ghia, Emanuela M; Zhang, Ling; Bao, Lei; Rassenti, Laura Z; Messer, Karen; Calin, George A; Croce, Carlo M; Kipps, Thomas J.

Blood; 124(4): 546-54, 2014 Jul 24.

Artículo en Inglés | MEDLINE | ID: mdl-24914134

12.

IL4-STAT6 signaling induces CD20 in chronic lymphocytic leukemia and this axis is repressed by PI3KÎ´ inhibitor idelalisib.

Sandova, Veronika; Pavlasova, Gabriela Mladonicka; Seda, Vaclav; Cerna, Katerina Amruz; Sharma, Sonali; Palusova, Veronika; Brychtova, Yvona; Pospisilova, Sarka; Fernandes, Stacey M; Panovska, Anna; Doubek, Michael; Davids, Matthew S; Brown, Jennifer R; Mayer, Jiri; Mraz, Marek.

Haematologica; 106(11): 2995-2999, 2021 11 01.

Artículo en Inglés | MEDLINE | ID: mdl-34196167

13.

B-cell receptor signalling and its crosstalk with other pathways in normal and malignant cells.

Seda, Vaclav; Mraz, Marek.

Eur J Haematol; 94(3): 193-205, 2015 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-25080849

14.

Ofatumumab added to dexamethasone in patients with relapsed or refractory chronic lymphocytic leukemia: Results from a phase II study.

Doubek, Michael; Brychtova, Yvona; Panovska, Anna; Sebejova, Ludmila; Stehlikova, Olga; Chovancova, Jana; Malcikova, Jitka; Smardova, Jana; Plevova, Karla; Volfova, Pavlina; Trbusek, Martin; Mraz, Marek; Bakesova, Denisa; Trizuljak, Jakub; Hadrabova, Marketa; Obrtlikova, Petra; Karban, Josef; Smolej, Lukas; Oltova, Alexandra; Jelinkova, Eva; Pospisilova, Sarka; Mayer, Jiri.

Am J Hematol; 90(5): 417-21, 2015 May.

Artículo en Inglés | MEDLINE | ID: mdl-25645263

15.

Identification of novel sequence variations in microRNAs in chronic lymphocytic leukemia.

Kminkova, Jana; Mraz, Marek; Zaprazna, Kristina; Navrkalova, Veronika; Tichy, Boris; Plevova, Karla; Malcikova, Jitka; Cerna, Katerina; Rausch, Tobias; Benes, Vladimir; Brychtova, Yvona; Doubek, Michael; Mayer, Jiri; Pospisilova, Sarka.

Carcinogenesis; 35(5): 992-1002, 2014 May.

Artículo en Inglés | MEDLINE | ID: mdl-24306027

16.

Detection of a deletion at 22q11 locus involving ZNF280A/ZNF280B/PRAME/GGTLC2 in B-cell malignancies: simply a consequence of an immunoglobulin lambda light chain rearrangement.

Mraz, Marek; Pospisilova, Sarka.

Br J Haematol; 186(4): e91-e94, 2019 08.

Artículo en Inglés | MEDLINE | ID: mdl-30989644

17.

MicroRNA-650 expression is influenced by immunoglobulin gene rearrangement and affects the biology of chronic lymphocytic leukemia.

Mraz, Marek; Dolezalova, Dasa; Plevova, Karla; Stano Kozubik, Katerina; Mayerova, Veronika; Cerna, Katerina; Musilova, Katerina; Tichy, Boris; Pavlova, Sarka; Borsky, Marek; Verner, Jan; Doubek, Michael; Brychtova, Yvona; Trbusek, Martin; Hampl, Ales; Mayer, Jiri; Pospisilova, Sarka.

Blood; 119(9): 2110-3, 2012 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-22234685

18.

Blockage of BCL-XL overcomes venetoclax resistance across BCL2-positive lymphoid malignancies irrespective of BIM status.

Dolnikova, Alexandra; Kazantsev, Dmitry; Klanova, Magdalena; Pokorna, Eva; Sovilj, Dana; Kelemen, Cristina Daniela; Tuskova, Liliana; Hoferkova, Eva; Mraz, Marek; Helman, Karel; Curik, Nikola; Machova Polakova, Katerina; Andera, Ladislav; Trnený, Marek; Klener, Pavel.

Blood Adv; 2024 May 07.

Artículo en Inglés | MEDLINE | ID: mdl-38713893

19.

MYB transcriptionally regulates the miR-155 host gene in chronic lymphocytic leukemia.

Vargova, Karin; Curik, Nikola; Burda, Pavel; Basova, Petra; Kulvait, Vojtech; Pospisil, Vit; Savvulidi, Filipp; Kokavec, Juraj; Necas, Emanuel; Berkova, Adela; Obrtlikova, Petra; Karban, Josef; Mraz, Marek; Pospisilova, Sarka; Mayer, Jiri; Trneny, Marek; Zavadil, Jiri; Stopka, Tomas.

Blood; 117(14): 3816-25, 2011 Apr 07.

Artículo en Inglés | MEDLINE | ID: mdl-21296997

20.

MicroRNAs regulate p21(Waf1/Cip1) protein expression and the DNA damage response in human embryonic stem cells.

Dolezalova, Dasa; Mraz, Marek; Barta, Tomas; Plevova, Karla; Vinarsky, Vladimir; Holubcova, Zuzana; Jaros, Josef; Dvorak, Petr; Pospisilova, Sarka; Hampl, Ales.

Stem Cells; 30(7): 1362-72, 2012 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-22511267

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