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1.

Engineering a therapeutic lectin by uncoupling mitogenicity from antiviral activity.

Swanson, Michael D; Boudreaux, Daniel M; Salmon, Loïc; Chugh, Jeetender; Winter, Harry C; Meagher, Jennifer L; André, Sabine; Murphy, Paul V; Oscarson, Stefan; Roy, René; King, Steven; Kaplan, Mark H; Goldstein, Irwin J; Tarbet, E Bart; Hurst, Brett L; Smee, Donald F; de la Fuente, Cynthia; Hoffmann, Hans-Heinrich; Xue, Yi; Rice, Charles M; Schols, Dominique; Garcia, J Victor; Stuckey, Jeanne A; Gabius, Hans-Joachim; Al-Hashimi, Hashim M; Markovitz, David M.

Cell; 163(3): 746-58, 2015 Oct 22.

Artículo en Inglés | MEDLINE | ID: mdl-26496612

2.

Application of Sublimation in the Synthesis and Crystal Growth of Organosulfones.

Alaa Eldin Refat, Lamis; Karpinska, Jolanta; Konda, Saidulu; Simmie, John M; Murphy, Paul V; McArdle, Patrick; Erxleben, Andrea.

Chemistry; : e202400672, 2024 Apr 16.

Artículo en Inglés | MEDLINE | ID: mdl-38623589

3.

MUC1 Glycopeptide Vaccine Modified with a GalNAc Glycocluster Targets the Macrophage Galactose C-type Lectin on Dendritic Cells to Elicit an Improved Humoral Response.

Gabba, Adele; Attariya, Riem; Behren, Sandra; Pett, Christian; van der Horst, Joost C; Yurugi, Hajime; Yu, Jin; Urschbach, Moritz; Sabin, Juan; Birrane, Gabriel; Schmitt, Edgar; van Vliet, Sandra J; Besenius, Pol; Westerlind, Ulrika; Murphy, Paul V.

J Am Chem Soc; 145(24): 13027-13037, 2023 06 21.

Artículo en Inglés | MEDLINE | ID: mdl-37279388

4.

What is the Sugar Code?

Gabius, Hans-Joachim; Cudic, Maré; Diercks, Tammo; Kaltner, Herbert; Kopitz, Jürgen; Mayo, Kevin H; Murphy, Paul V; Oscarson, Stefan; Roy, René; Schedlbauer, Andreas; Toegel, Stefan; Romero, Antonio.

Chembiochem; 23(13): e202100327, 2022 07 05.

Artículo en Inglés | MEDLINE | ID: mdl-34496130

5.

Targeting osteoarthritis-associated galectins and an induced effector class by a ditopic bifunctional reagent: Impact of its glycan part on binding measured in the tissue context.

Manning, Joachim C; Baldoneschi, Veronica; Romero-Hernández, Laura L; Pichler, Katharina M; GarcÍa Caballero, Gabriel; André, Sabine; Kutzner, Tanja J; Ludwig, Anna-Kristin; Zullo, Valerio; Richichi, Barbara; Windhager, Reinhard; Kaltner, Herbert; Toegel, Stefan; Gabius, Hans-Joachim; Murphy, Paul V; Nativi, Cristina.

Bioorg Med Chem; 75: 117068, 2022 Oct 18.

Artículo en Inglés | MEDLINE | ID: mdl-36327696

6.

Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen.

Gabba, Adele; Bogucka, Agnieszka; Luz, John G; Diniz, Ana; Coelho, Helena; Corzana, Francisco; Cañada, Francisco Javier; Marcelo, Filipa; Murphy, Paul V; Birrane, Gabriel.

Biochemistry; 60(17): 1327-1336, 2021 05 04.

Artículo en Inglés | MEDLINE | ID: mdl-33724805

7.

Imitating evolution's tinkering by protein engineering reveals extension of human galectin-7 activity.

Ludwig, Anna-Kristin; Michalak, Malwina; Gabba, Adele; Kutzner, Tanja J; Beckwith, Donella M; FitzGerald, Forrest G; García Caballero, Gabriel; Manning, Joachim C; Kriegsmann, Mark; Kaltner, Herbert; Murphy, Paul V; Cudic, Maré; Kopitz, Jürgen; Gabius, Hans-Joachim.

Histochem Cell Biol; 156(3): 253-272, 2021 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-34152508

8.

Cyclisations and Strategies for Stereoselective Synthesis of Piperidine Iminosugars.

Dhara, Debashis; Dhara, Ashis; Bennett, Jack; Murphy, Paul V.

Chem Rec; 21(11): 2958-2979, 2021 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-34713557

9.

Immunomodulatory properties of characellide A on human peripheral blood mononuclear cells.

Marcella, Simone; Afoullouss, Sam; Thomas, Olivier P; Allcock, A Louise; Murphy, Paul V; Loffredo, Stefania.

Inflammopharmacology; 29(4): 1201-1210, 2021 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-34241784

10.

Influence of protein (human galectin-3) design on aspects of lectin activity.

García Caballero, Gabriel; Beckwith, Donella; Shilova, Nadezhda V; Gabba, Adele; Kutzner, Tanja J; Ludwig, Anna-Kristin; Manning, Joachim C; Kaltner, Herbert; Sinowatz, Fred; Cudic, Mare; Bovin, Nicolai V; Murphy, Paul V; Gabius, Hans-Joachim.

Histochem Cell Biol; 154(2): 135-153, 2020 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-32335744

11.

Correction to: Influence of protein (human galectin-3) design on aspects of lectin activity.

García Caballero, Gabriel; Beckwith, Donella; Shilova, Nadezhda V; Gabba, Adele; Kutzner, Tanja J; Ludwig, Anna-Kristin; Manning, Joachim C; Kaltner, Herbert; Sinowatz, Fred; Cudic, Mare; Bovin, Nicolai V; Murphy, Paul V; Gabius, Hans-Joachim.

Histochem Cell Biol; 154(2): 155, 2020 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-32514791

12.

Beyond the Crystal Structure of Human Macrophage C-Type Lectin.

Gabba, Adele; Murphy, Paul V; Kiessling, Laura L; Birrane, Gabriel.

Biochemistry; 63(2): 191-193, 2024 Jan 16.

Artículo en Inglés | MEDLINE | ID: mdl-38165812

13.

How altering the modular architecture affects aspects of lectin activity: case study on human galectin-1.

Kutzner, Tanja J; Gabba, Adele; FitzGerald, Forrest G; Shilova, Nadezhda V; García Caballero, Gabriel; Ludwig, Anna-Kristin; Manning, Joachim C; Knospe, Clemens; Kaltner, Herbert; Sinowatz, Fred; Murphy, Paul V; Cudic, Mare; Bovin, Nicolai V; Gabius, Hans-Joachim.

Glycobiology; 29(8): 593-607, 2019 07 19.

Artículo en Inglés | MEDLINE | ID: mdl-31091305

14.

N-Alkyl-1,5-dideoxy-1,5-imino-l-fucitols as fucosidase inhibitors: Synthesis, molecular modelling and activity against cancer cell lines.

Zhou, Jian; Negi, Arvind; Mirallai, Styliana I; Warta, Rolf; Herold-Mende, Christel; Carty, Michael P; Ye, Xin-Shan; Murphy, Paul V.

Bioorg Chem; 84: 418-433, 2019 03.

Artículo en Inglés | MEDLINE | ID: mdl-30554081

15.

Anomer Preferences for Glucuronic and Galacturonic Acid and Derivatives and Influence of Electron-Withdrawing Substituents.

Kerins, Louise; Byrne, Sylvester; Gabba, Adele; Murphy, Paul V.

J Org Chem; 83(15): 7714-7729, 2018 08 03.

Artículo en Inglés | MEDLINE | ID: mdl-29969902

16.

Teaming up synthetic chemistry and histochemistry for activity screening in galectin-directed inhibitor design.

Roy, René; Cao, Yihong; Kaltner, Herbert; Kottari, Naresh; Shiao, Tze Chieh; Belkhadem, Karima; André, Sabine; Manning, Joachim C; Murphy, Paul V; Gabius, Hans-Joachim.

Histochem Cell Biol; 147(2): 285-301, 2017 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-28013366

17.

Merging carbohydrate chemistry with lectin histochemistry to study inhibition of lectin binding by glycoclusters in the natural tissue context.

André, Sabine; Kaltner, Herbert; Kayser, Klaus; Murphy, Paul V; Gabius, Hans-Joachim.

Histochem Cell Biol; 145(2): 185-99, 2016 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-26553286

18.

Carbohydrate Chemistry: Critical for our Future.

Murphy, Paul V; Ramesh, Namakkal G.

Chem Rec; 21(11): 2928-2929, 2021 11.

Artículo en Inglés | MEDLINE | ID: mdl-34766718

19.

Multivalent Carbohydrate-Lectin Interactions: How Synthetic Chemistry Enables Insights into Nanometric Recognition.

Roy, René; Murphy, Paul V; Gabius, Hans-Joachim.

Molecules; 21(5)2016 May 13.

Artículo en Inglés | MEDLINE | ID: mdl-27187342

20.

Synthesis of Migrastatin Analogues as Inhibitors of Tumour Cell Migration: Exploring Structural Change in and on the Macrocyclic Ring.

Lo Re, Daniele; Zhou, Ying; Mucha, Joanna; Jones, Leigh F; Leahy, Lorraine; Santocanale, Corrado; Krol, Magdalena; Murphy, Paul V.

Chemistry; 21(50): 18109-21, 2015 Dec 07.

Artículo en Inglés | MEDLINE | ID: mdl-26531227

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