Does the Low-Intensity Laser Protocol Affect Tissue Healing After Third Molar Removal?

PURPOSE: Studies have shown that laser therapy is a recommended therapy for improving the postoperative period in patients undergoing extraction of the third molars; however, there is still no definition regarding the best protocol to be used. The aim of this study was to measure and compare periodontal tissue healing using 2 different laser protocols. MATERIALS AND METHODS: A double-blinded, randomized, prospective study with patients submitted to inferior third molar extraction was performed, with the sample divided into 3 groups according to the laser application protocol and followed for 6 months: group I, 10 J/cm2; group II, 30 J/cm2; and group III, sham. The primary variable was probing depth, and the secondary variables were trismus, facial edema, and pain. RESULTS: The sample was composed of 57 patients: 19 in group I, 20 in group II, and 18 in group III. Analysis of the variables showed statistically significant differences between both groups that received laser therapy, with values of 1.46 for edema control on the third day and 0.54 on the seventh day in group I (P = .017) and 1.26 and 0.52, respectively, in group II (P = .001) compared with 0.59 and 0.49, respectively, in the sham group (P = .702), as well as a statistically significant difference for the 10-J/cm2 laser protocol for probing depth, with values of 7.58 mm preoperatively and 9.09 mm after 6 months (P = .013). CONCLUSIONS: The use of the low-intensity laser as adjuvant therapy after third molar extraction was more effective in the group undergoing the 10-J/cm2 laser protocol for improving periodontal tissue healing and in both laser therapy groups for reducing facial edema.

Use of Buccal Fat Pad in the Treatment of Peri-Implant Mucosal Defect: A Case Report.

The present study describes a clinical case in which the buccal fat pad (BFP) was used to improve the contour of the peri-implant mucosa. To our knowledge, this is the first case report of such an application in the literature. A 58-year-old woman presented with teeth #2 and #3 missing and an indication for extraction of tooth #4. After clinical examination and CBCT analysis, immediate implants were placed in the region of the extracted tooth and that of tooth #2 for prosthetic rehabilitation using a three-unit fixed partial denture. There was an extensive mucosal defect in the region of tooth #3, with vertical and horizontal changes in the contour of the mucosa. As an alternative to the use of a subepithelial connective tissue graft, we opted for displacement of the BFP and its accommodation on the alveolar ridge of tooth #3 to improve the buccal tissue contour. After 5 years of follow-up, satisfactory gain and maintenance of mucosal volume were observed in the treated area, as well as improvement of buccal tissue contour. The use of BFP seems to be a feasible alternative for filling and treating peri-implant mucosal defects.

Comparison of Three Anxiety Management Protocols for Extraction of Third Molars With the Use of Midazolam, Diazepam, and Nitrous Oxide: A Randomized Clinical Trial.

PURPOSE: The objective of the present study was to compare 3 sedation protocols using diazepam, midazolam, and nitrous oxide. PATIENTS AND METHODS: A total of 120 patients with an indication for extraction of third molars were selected. All 120 patients had had moderate to severe levels of anxiety according to the Corah Dental Anxiety Scale. The patients were randomly divided into 3 groups. The patients' vital signs were measured, and the results analyzed by descriptive statistical analysis and statistical tests of comparison. RESULTS: No statistically significant differences were found in the patients' heart rate. However, the differences in the systolic and diastolic blood pressure were statistically significant after 15 minutes of nitrous oxide sedation. The oximetry data showed no differences among the 3 sedation protocols. We also found no statistically significant differences in the retrograde amnesia test. The differences in anxiety from preoperatively to postoperatively were statistically significant for all techniques, demonstrating their effectiveness in anxiety control. CONCLUSIONS: All 3 preoperative sedation techniques for anxious patients undergoing extraction of third molars used in the present study were effective in controlling the anxiety, with little effect on the patients' vital signs and retrograde amnesia.

Porous titanium and Ti-35Nb alloy: effects on gene expression of osteoblastic cells derived from human alveolar bone.

Tests on titanium alloys that possess low elastic modulus, corrosion resistance and minimal potential toxicity are ongoing. This study aimed to evaluate the behavior of human osteoblastic cells cultured on dense and porous Titanium (Ti) samples comparing to dense and porous Ti-35 Niobium (Ti-35Nb) samples, using gene expression analysis. Scanning electronic microscopy confirmed surface porosity and pore interconnectivity and X-ray diffraction showed titanium beta-phase stabilization in Ti-35Nb alloy. There were no differences in expression of transforming growth factor-ß, integrin-ß1, alkaline phosphatase, osteopontin, macrophage colony stimulating factor, prostaglandin E synthase, and apolipoprotein E regarding the type of alloy, porosity and experimental period. The experimental period was a significant factor for the markers: bone sialoprotein II and interleukin 6, with expression increasing over time. Porosity diminished Runt-related transcription factor-2 (Runx-2) expression. Cells adhering to the Ti-35Nb alloy showed statistically similar expression to those adhering to commercially pure Ti grade II, for all the markers tested. In conclusion, the molecular mechanisms of interaction between human osteoblasts and the Ti-35Nb alloy follow the principal routes of osseointegration of commercially pure Ti grade II. Porosity impaired the route of transcription factor Runx-2.

A large dentigerous cyst treated with decompression and orthosurgical traction: a case report.

This article presents the case of an 8-year-old patient who presented with a large radiolucency associated with the maxillary left canine and a supernumerary tooth. A computed tomography scan showed the radiolucency was in close proximity to the roots of the anterior teeth, with no areas of root resorption, and expansion into the left maxillary sinus. The boundaries of the maxillary sinus floor were still preserved. After positive aspiration of intralesional liquid and due to the large size of the radiolucency, a decompression technique was selected to preserve the permanent canine. Surgery was performed to remove the supernumerary tooth, followed by orthodontic treatment and surgery to allow access for orthodontic traction of the permanent canine. More than 5 years post-treatment, no recurrence was observed and the therapeutic option to position and preserve the permanent canine was successful.

Influence of osteopenia in autogenous bone graft healing with or without expanded polytetrafluoroethylene membranes: histologic and histomorphometric study in rats.

PURPOSE: The aim of this study was to quantitatively evaluate and qualitatively describe autogenous bone graft healing with or without an expanded polytetrafluoroethylene (e-PTFE) membrane in ovariectomized rats. MATERIALS AND METHODS: Eighty Wistar rats, weighing approximately 300 g each, were used. A graft was obtained from the parietal bone and fixed to the sidewall of each animal's left mandibular ramus. The animals were randomly divided into four experimental groups (n = 20 in each group): group 1, sham operated and autogenous bone graft only; group 2, sham operated and autogenous bone graft covered by e-PTFE membrane; group 3, ovariectomized (OVX) and autogenous bone graft only; group 4, OVX and autogenous bone graft covered by e-PTFE membrane. The animals were sacrificed at five different time points: immediately after grafting or at 7, 21, 45, or 60 days after grafting. Histologic examination and morphometric measurement of the sections were performed, and values were submitted to statistical analyses. RESULTS: Both groups (sham and OVX) experienced loss of the original graft volume when it was not covered by the membrane, whereas use of the membrane resulted in additional bone formation beyond the edges of the graft and under the membrane. Histologic analysis showed integration of the grafts in all animals, although a larger number of marrow spaces was found in OVX groups. CONCLUSIONS: Association of bone graft with an e-PTFE membrane resulted in maintenance of its original volume as well as formation of new bone that filled the space under the membrane. Osteopenia did not influence bone graft repair, regardless of whether or not it was associated with e-PTFE membrane, but descriptive histologic analysis showed larger numbers of marrow spaces in the bone graft and receptor bed and formation of new bone in the OVX animals.

Evaluation of the impact of preoperative use of dexamethasone and cyclobenzaprine in surgical extraction of lower third molars on trismus by electromyographic analysis.

PURPOSE: The aim of this study was to evaluate the influence of cyclobenzaprine and dexamethasone on ​the electrical activity of the masticatory muscles in patients who had undergone lower third molar surgery. METHODS: Thirty bilateral impacted lower third molars with indication of extraction were randomised into three groups: the control group, the dexamethasone, and the cyclobenzaprine group. To obtain muscular electrical activity and mouth opening, an electromyographic device was used at mandibular rest and maximum voluntary contraction and compared pre- and post-operatively. RESULTS: During muscle contraction, no significant difference was observed in the electromyographic records on the non-operated side. On the operated side, there was a reduction in electrical activity for both drugs pre-operatively and immediately post-operatively compared to the control group. All pharmacological agents promoted a higher mouth opening compared to control group. CONCLUSION: The results suggest that dexamethasone and cyclobenzaprine may be useful as an adjuvant in the prevention of motor dysfunctions in third molar surgery.

Multidisciplinary action in a patient with cleft lip and palate: esthetic-functional dentofacial treatment for more than two decades / Atuação multidisciplinar em paciente com fissura lábio palatina: tratamento estético-funcional dento-facial de mais de duas décadas

Cleft lip and palate is a very common congenital defect in which embryonic facial processes do not achieve the ideal facial formation during their development which can cause malformation. Multiple dentistry specializations, especially oral and maxillofacial, orthodontics, oral rehabilitation and dental aesthetics are required in order to correct lip and oral cavity malformations by this congenital defect with the objective of functional and aesthetics improvement. The clinical case reported show the multidisciplinary approach in a patient with cleft lip and palate implementing an aesthetic and functional dentofacial rehabilitation. The case involves a 27-year-old female patient LCLG, Caucasian, with the presence of unilateral congenital cleft lip and palate on the left side, who started rehabilitative and reparative treatment at 3 months of age. She then started pediatric orthodontic treatment for angle class 3 crossbite correction at 7 years of age. After complete replacement of deciduous to permanent dentition at the age of 11, the patient started orthodontic treatment with a fixed appliance for several years and restorative treatment with composite resin reanatomize the anterior teeth due to agenesis of elements 22 and 25. After a few years when the resin restorations were no longer biologically favorable, an aesthetic rehabilitation treatment with ceramic laminates was planned through smile digital planning soon after completing the orthodontic treatment. This case report demonstrates that high aesthetic, functional and psychological expectations of a patient with congenital defect compromise throughout her life were met through a multidisciplinary dental treatment based on correct diagnosis and digital planning (AU)

A fissura labiopalatal é um defeito congênito muito comum, no qual os processos faciais embrionários não atingem a formação facial ideal durante o seu desenvolvimento, podendo causar malformações. Múltiplas especializações da odontologia, principalmente buco-maxilo-facial, ortodontia, reabilitação oral e estética dental são necessárias para corrigir as malformações labiais e da cavidade oral por esse defeito congênito com o objetivo de melhoria funcional e estética. O caso clínico relatado mostra a abordagem multidisciplinar em um paciente com fissura labiopalatal implementando uma reabilitação dentofacial estética e funcional. O caso envolve uma paciente do sexo feminino, 27 anos, LCLG, branca, com presença de fissura labiopalatal congênita unilateral à esquerda, que iniciou tratamento reabilitador e reparador aos 3 meses de idade. Após a substituição completa da dentição decídua pela permanente aos 11 anos de idade, a paciente iniciou tratamento ortodôntico com aparelho fixo por vários anos, e tratamento restaurador com resina composta para reanatomizar os dentes anteriores devido à agenesia dos elementos 22 e 25. Após alguns anos em que as restaurações em resina não eram mais favoráveis biologicamente, foi planejado um tratamento reabilitador estético com laminados cerâmicos através do planejamento digital do sorriso logo após a finalização do tratamento ortodôntico. Este relato de caso demonstra que as altas expectativas estéticas, funcionais e psicológicas de uma paciente com comprometimento de defeito congênito ao longo de sua vida foram atendidas por meio de um tratamento odontológico multidisciplinar baseado em diagnóstico correto e planejamento digital (AU)

Volume and effectiveness assessment of articain 4% versus mepivacaine 2% used in third molar surgery: randomized, double-blind, split-mouth controlled clinical trial

BACKGROUND: The different indications for extraction of the lower third molars, require resources to manage pain and discomfort, such as, for example, adequate anesthetic techniques, and the type of anesthetic used can influence the management of pain in tooth extractions. Few studies in the literature compare the anesthetics 4% articaine hydrochloride and 2% mepivacaine hydrochloride showing evidence that both allow for successful pain management. This study sought to compare the volume, efficacy and safety of these two anesthetic drugs, both associated with epinephrine at a ratio of 1:100,000, used in the extraction of lower third molars. MATERIAL AND METHODS: A controlled, clinical, split-mouth compared these both local anesthetics in a sample of 20 patients requiring bilateral extraction of teeth. Pain was the main parameter to be assessed by means of the visual analogue scale (VAS) applied during and immediately after the surgery. Hemodynamic parameters, adverse events, presence of paresthesia and satisfaction of patients and surgeon were also analysed. RESULTS: Pain management was more effective with mepivacaine up to two hours after surgery (p = 0.014), whereas the surgeon was more satisfied with the use of articaine during divulsion and suture (p < 0.05). However no statistically significant differences were found between both anesthetics regarding pain perception. CONCLUSIONS: It was observed that both anesthetics are efficient and safe in the management of pain for extraction of third molars, in which less amount of mepivacaine is needed. The satisfaction of patients and surgeon was the same for both anesthetics, with articaine being highlighted during divulsion and suture

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Osteoblast response to porous titanium and biomimetic surface: In vitro analysis.

OBJECTIVE: This study analyzed the behavior of human osteoblasts cultured on porous titanium specimens, with and without biomimetic treatment, compared to dense titanium. DESIGN: The experiment had seven groups: Group 1: cells cultured on polystyrene of culture plate wells; Group 2: cells cultured on dense titanium specimen; Group 3: specimen with 33.79% of pores; Group 4: 41.79% of pores; Groups 5, 6 and 7: specimens similar to groups 2, 3 and 4, yet with biomimetic treatment. Real time-polymerase chain reaction with reverse transcription of the following genes was performed: prostaglandin E2 synthase, integrin ß1, osterix, Runx2, Interleukin 6, macrophage colony stimulating factor, apolipoprotein E and others. The study achieved data on cell adhesion, growth and viability, total protein content, alkaline phosphatase activity and quantity of mineralized nodule formations. Data were statistically evaluated. RESULTS: Adherent cells and alkaline phosphatase activity were similar in titanium specimens, regardless of the groups. Biomimetic treatment reduced the total protein activity and the viability of tested cells. Most tested genes had statistically similar expression in all groups. CONCLUSION: The tested porosities did not cause alterations in osteoblast behavior and the biomimetic treatment impaired the biocompatibility of titanium causing cytotoxicity.

Immunolocalization of markers for bone formation during guided bone regeneration in osteopenic rats.

OBJECTIVE: The aim of this paper was to evaluate the repair of onlay autogenous bone grafts covered or not covered by an expanded polytetrafluoroethylene (e-PTFE) membrane using immunohistochemistry in rats with induced estrogen deficiency. MATERIAL AND METHODS: Eighty female rats were randomly divided into two groups: ovariectomized (OVX) and with a simulation of the surgical procedure (SHAM). Each of these groups was again divided into groups with either placement of an autogenous bone graft alone (BG) or an autogenous bone graft associated with an e-PTFE membrane (BGM). Animals were euthanized on days 0, 7, 21, 45, and 60. The specimens were subjected to immunohistochemistry for bone sialoprotein (BSP), osteonectin (ONC), and osteocalcin (OCC). RESULTS: All groups (OVX+BG, OVX+BMG, SHAM+BG, and SHAM+BMG) showed greater bone formation, observed between 7 and 21 days, when BSP and ONC staining were more intense. At the 45-day, the bone graft showed direct bonding to the recipient bed in all specimens. The ONC and OCC showed more expressed in granulation tissue, in the membrane groups, independently of estrogen deficiency. CONCLUSIONS: The expression of bone forming markers was not negatively influenced by estrogen deficiency. However, the markers could be influenced by the presence of the e-PTFE membrane.

Bone grafting and osseointegration in the area of maxillary tooth agenesis. Case report / Incorporação de enxertos ósseos e osseointegração em área de agenesia dentária maxilar. Caso clínico

The high dental implant success rate is directly linked to the presence of adequate bone volume, which enables and maintains the osseointegration of dental implants. This study aimed to report a clinical case of a female with agenesis of the right maxillary lateral incisor (12), due to cleft lip and palate. Because the bone and mucosal defects of the area, the treatment planning comprised guided bone regeneration with the association of autogenous bone, platelet rich plasm (PRP), and expanded polytetrafluoroethylene membrane (e-PTFE,Gore-Tex), performed in 2005. After nine months, a new evaluation was carried out and revealed that the area was still not suitable for implant placement. Thus, an allogenous bone graft was planned. Elapsed another nine months, the implant was placed. After six months, the implant was reopened and a metal-ceramic crown was installed. The 5-year following-up appointment showed the presence of fistula with purulent secretion at the buccal cortical plate. We attempted to control the fistula with antibiotics and follow-up clinically and radiographically. The examinations suggested a communication with the right nasal cavity, which decreased until nowadays. The osseointegrated dental implant was in function, without symptomatology. The autogenous bone graft is still more effective than allogenous bone graft. Further studies are necessary to achieve better evaluations. (AU)

A realização de elevadas taxas de sucesso em implantodontia está diretamente ligada à presença de volume de tecido ósseo adequado, que permiti e mantém a osseointegração dos implantes dentários. O objetivo deste trabalho foi apresentar o caso clínico da paciente, com agenesia do dente 12, decorrente da fissura lábio-palatina. Devido ao defeito ósseo e mucoso na região, foi planejada a realização da técnica de regeneração óssea guiada, associando a utilização de osso autógeno, plasma rico em plaquetas (PRP) e membrana de politetrafluoretileno expandido (PTFE-e, Gore-Tex) realizado em 2005. Após 9 meses, nova avaliação foi realizada, porém a área estava inadequada para o posicionamento do implante, optou-se por um novo enxerto, agora alógeno. E após mais 9 meses foi instalado o implante. Aguardou-se 6 meses até a reabertura, para o implante entrar em função por meio de uma coroa metalocerâmica. Passados 5 anos de controle a paciente apresentou uma fístula com secreção purulenta na parede óssea vestibular, controlada com terapia medicamentosa, e após alguns anos, pelo exame clínico e tomográfico, sugeriu-se comunicação com a cavidade nasal direita, porém regrediu e está sendo preservada até os dias atuais, com o implante osseointegrado em função, sem sintomatologia. O enxerto ósseo autógeno ainda é superior em relação ao alógeno. Outros estudos são necessários para melhores avaliações. (AU)

Use of ozone therapy together to low power laser in osteonecrosis induced bisphosphonates: clinical case / O uso da ozônio terapia junto ao laser de baixa potência em osteonecrose induzida por bisfosfonatos: caso clínico

Considerando a associação causal provável entre o uso de bisfosfonatos e osteonecrose da mandíbula, bem como o elevado número de prescrições e dessas drogas todos os anos, este trabalho tem como objetivo mostrar um tratamento diferente. O uso combinadode terapia de ozônio e laser na regeneração de tecidos e reparação óssea em pacientes com osteonecrose induzida por bisfosfonatos, realizada pela disciplina de Cirurgia bucomaxilofacial e Traumatologia da Universidade Estadual Paulista “Júlio de Mesquita Filho”. Paciente do sexo feminino, branca, 53 anos, depois de um câncer de mama teve uma evolução de metástases ósseas em todo o corpo, iniciou o tratamento de quimioterapia intravenosa utilizando pamidronato 90 mg mensal a partir de 2007 que tem sido utilizado até os dias atuais, devido à estabilização da doença. A paciente procurou a instituição com sintomatologia dolorosa na mandíbula e maxila, pelo exame clínico e de imagem foram diagnosticados sítios iniciais sugestivos de osteonecrose induzida por bisfosfonatos. Na tentativa de reduzir os sintomas e sinais clínicos, para impedir o avanço das lesões, recomendamos o tratamento por terapia de ozônio junto ao laser infravermelho de baixa potência, quemostrou redução satisfatória dos sítios de necrose óssea. Embora haja variações amplas e dificuldades em tratamento de osteonecrose induzida por bisfosfonatos, foi possível regressão das lesões através das terapias conjuntas aplicadas, bem como a melhoria da expectativa de vida do paciente.

Considering the probable causal association between the use of bisphosphonates and osteonecrosis of the jaw, as well as the high number of prescriptions and use these drugs every year, this paper aims to show different treatment. The combined use of ozone therapy and laser therapy in tissue regeneration and bone repair in patients with osteonecrosis induced by bisphosphonates, held by the discipline of Oral and Maxillofacial Surgery and Traumatology, Paulista State University “Júlio de Mesquita Filho”. Female patient, white, 53 years after a breast cancer had an evolution for bone metastases throughout the body, and start the chemotherapy treatment using intra-venous pamidronate 90 mg monthly from 2007 which has been used to the present day, due to disease stabilization. The patient sought the institution complaining of painful symptoms in the mandible and maxilla, and the clinical examination and CT were diagnosed initial sites suggestive of osteonecrosis induced by bisphosphonates. In seeking to reduce the symptoms and clinical signs, to prevent progress in the lesions, we recommend treatment by ozone therapy together to infrared low-power laser, which showed satisfactory reduction in bone necrosis sites. Although there are wide variations and difficulties in treatments for osteonecrosis induced by bisphosphonates, it was possible regression of the lesions through the joint processing applied, and the improvement in life expectancy of the patient.

Evaluation of implant osseointegration success: Retrospective study at update course / Avaliação do sucesso da osseointegração dos implantes em curso de formação: Estudo retrospectivo

With the scientific and technological advances, the life expectancy of the population has increased over the years. With the advent of dental implants, a new possibility of treatment for oral rehabilitation was created to help or even help overcome the limits of conventional fixed dentures, removable and mainly total. Compared to conventional rehabilitation treatment on natural teeth, rehabilitation on implants has higher rates of success and longevity. Material and Methods: For this research we evaluated the medical records of patients who received surgical treatment for implant placement in the update current school of Implantology ECO (Continuing Studiesin Dentistry) in São José dos Campos, in the 2008‘ period to 2012, in order to obtain, analyze and relate the following criteria: the patient gender; year and number of installed dental implants; the region of implant installation; the trademark of the installed implant and the success ful osseointegration, or processin which there is a rigid fixation between the living bone and the surface of the implant installed. Results: According to the analyzed data, it was observed, along five years, a total of 434 implants placed in patients, mostly women in the mandibular region. However, the total loss was of 5 implants, most in the maxilla and in men, 3 of these, cone-Morse implants, one internal and one external hexagon. Conclusion: Thus, the success rate in the osseointegration implants seems tobe more influenced by patient selection and surgical and prosthetic guidelines, compared the experience of the dentist...

Com os avanços científicos e tecnológicos, a expectativa de vida da população tem aumentado ao longo dos anos. Com o advento dos implantes dentários, uma nova possibilidade de tratamento para reabilitação oral foi criado para ajudar ou até mesmo superar os limites de próteses fixas convencionais, removíveis e até a total. Em comparação com o tratamento de reabilitação convencional em dentes naturais, reabilitação sobreimplantes tem maiores taxas de sucesso e longevidade. Material e Métodos: Para esta pesquisa foram avaliados os prontuários de pacientes que receberam tratamento cirúrgico para a colocação dos implantes no curso de atualização de Implantodontia da escola ECO (Estudos Continuados em Odontologia), em São José dos Campos, no período de 2008 a 2012, a fim de obter, analisar e relacionar os seguintes critérios: o sexo do paciente; ano e o número de implantes dentários instalados; a região de instalação do implante; a marca do implante instalado e a osteointegração bem sucedida, processo no qual há uma fixação rígida entre o osso vivo e a superfície do implante instalado. Resultados: De acordo com os dados analisados, verificou-se, ao longo de cinco anos, um total de 434 implantes colocados em pacientes, a maioria mulheres na região mandibular. No entanto, a perda total foi de 5 implantes, a maioria na maxila e nos homens, três deles, implantes cone-morse, um hexágono interno e dois externos. Conclusão: Assim, a taxa de sucesso dos implantes parece ser mais influenciada pela selecção do paciente e orientações cirúrgicas e protéticas, em comparação a experiência do dentista...

Electromyographic evaluation of superficial masseter and anterior temporal muscles after using cyclobenzaprine during extraction of impacted third molars / Avaliação eletromiografica dos músculos masseter superficial e temporal anterior após uso de ciclobenzaprina na extração de terceiros molares inclusos

Objective: Avaliamos a influência do cloridrato deciclobenzaprina (Miosan,10mg/via oral/doseúnica), administrado previamente à extração de terceiros molares inferiores inclusos na atividade elétrica dos músculos masseter superficial e temporal anterior, por meio de registros eletromiográficos, na condição de repouso, contração isométrica voluntária máxima e abertura máxima da boca,nos períodos: pré cirúrgico, cirúrgico, e pós cirúrgico (7, 15 e 30 dias), e assim contribuir com a discussão do diagnóstico de disfunções do sistema estomatognático frente aos procedimentos operatórios de longa duração. Material e Métodos Foram selecionados 20 pacientes, com indicação de extração de terceiro molar inferior incluso e impactado, sem comprometimento sistêmico, com ausência de reações alérgicas aos fármacos utilizados,de ambos os sexos, provenientes da Disciplina de Cirurgia e Traumatologia Bucomaxilofacial do Instituto de Ciência e Tecnologia de São José dos Campos da Unesp. Utilizamos o eletromiógrafo modelo EMG-800C da EMG System do Brasil Ltda de quatro canais de entrada, previamente calibrado,com eletrodos ativos e ganho de amplificação de 20vezes. Além disso, foi utilizado um canal acoplado ao sistema para registro de abertura bucal (goniômetromandibular). Resultados: Observamos que a atividade elétrica dos músculos estudados é reduzida na fase inicial do procedimento cirúrgico, embora não se altere significativamente pela presença do fármaco, durante todos os períodos avaliados.O músculo masseter, na presença do fármaco,restabelece sua atividade logo após o período pósoperatório ao contrário do grupo controle que ocorre após 7 dias. Observamos um aumento ....

Objective: The influence of cyclobenzaprine hydrochloride (Miosan,10mg/orally/single dose), taken prior to the extraction of impacted mandibular third molars on the electrical activity of superficial masseter and anterior temporal muscles was evaluated through electromyographic recordings aiming at contributing to the discussion of the diagnosis of stomatognathic dysfunctions in relation to long lasting operative procedures. Material and Methods: Twenty patients referred for the extraction of impacted and embedded mandibular third molars at the Discipline of Oral and maxillofacial Surgery and Traumatology (Institute of Science and Technology of São José dos Campos/Unesp), without systemic disease and allergic reactions to the drugs used, both sexes were selected. An electromyographer model EMG-800C (EMG System do Brasil Ltd.), with four input channels, previously calibrated with active electrodes and 20-fold amplification gain was used together with a channel linked to the system to record the mouth opening (mandibular goniometer). The following conditions were assessed: rest, maximum voluntary isometric contraction, and maximum mouth opening, at the following periods: presurgical, surgical, and post-surgical (7, 15, and 30days). Results: The electrical activity of the studied muscles was reduced at the beginning of the surgical procedure, but it did not significantly alter by the administration of the drug at all evaluated periods.The masseter muscle, after the drug administration, reestablished its activity just after the postoperative period, unlikely the control group, whichre established the activity after 7 days ....

Osteoradionecrosis: case report / Osteorradionecrose: relato de caso

Pacientes submetidos à radioterapia como parte do tratamento do câncer de cabeça e pescoço estão sujeitos a desenvolver osteorradionecrose (ORN). As exodontias têm sido implicadas como principal fator desencadeador de ORN, particularmente em região de molares inferiores. A osteorradionecrose tem sido reportada em até 20% dos pacientes irradiados submetidos à exodontia, e é reconhecida como a mais severa complicação da radioterapia em mandíbula, acarretando grande desconforto e perda na qualidade de vida do paciente. O risco de desenvolvimento de ORN é relacionado à dose, técnica e volume de tecido irradiado, e outros fatores predisponentes como: exodontia no período peri-radioterapia, local de extração, doença periodontal preexistente, trauma causado por próteses mal adaptadas, higiene oral deficiente, deficiência nutricional, uso de álcool e fumo, e doenças sistêmicas. A injúria celular e hipóxia causadas por redução do suprimento vascular, reduzem a capacidade de recuperação dos tecidos moles e do osso, predispondo-os a necrose e osteonecrose inclusive espontânea. O manejo clínico da osteorradionecrose, é complexo e dependendo do grau de acometimento pode requerer além de uso de analgésicos e antibioticoterapia a adoção de procedimentos cirúrgicos, tendo como objetivo eliminar a dor, controlar a infecção e evitar ou reduzir a progressão da lesão.O objetivo deste trabalho é relatar um caso de osteorradionecrose atendido na clínica multidisciplinar do Projeto Onco – ICT/ UNESP São José dos Campos.

Patients undergoing radiotherapy alone or as part of the treatment of head and neck cancer are likely to develop osteoradionecrosis (ORN). Dental extractions have been inferred as the main triggering factor of ORN, particularly in mandibular molars. The osteoradionecrosis has been reported in up to 20% of irradiated patients undergoing dental extraction and is recognized as the most severe complication of radiotherapy in the mandible, causing great discomfort and loss of quality of life of patients. The risk of ORN development is related to the dose, technique, and volume of irradiated tissue, and other predisposing factors such as: extraction at peri-radiotherapy period, site of extraction, pre-existing periodontal disease, general trauma, poor oral hygiene, nutritional deficiency, alcohol and smoking, and systemic diseases. The cellular injury and hypoxia caused by decreased blood supply reduce the recoverability of soft tissue and bone, predisposing them to necrosis and osteonecrosis, even spontaneous. Clinical management of osteoradionecrosis is complex and depending on the degree of involvement, it may require analgesics and antibiotics in addition to the adoption of surgical procedures, aiming to eliminate pain, control infection, and prevent orreduce the progression ofthe lesion. This paper aimed to report a case of osteoradionecrosis treated in the multidisciplinary clinic of the Onco Project - ICT/UNESP (São José dos Campos/SP, Brazil). A female patient aged 65 years with osteoradionecrosis and fistula after radiotherapy of squamous cell carcinoma in gingiva was submitted to tooth extraction, antibiotic therapy and local care with good response and flow interruption through the fistula. During the treatment, the carcinoma relapsed and the patient was referred for oncologic treatment.

Hemodynamic evaluation of normotensive and hypertensive patients undergoing dental extraction under local anesthesia with 3% prilocaine with felypressin / Avaliação hemodinâmica de pacientes normotensos e hipertensos submetidos à exodontia sob anestesia local com cloridrato de prilocaína 3% associado à felipressina

Objetivo: Este estudo avaliou as alterações hemodinâmicas de pacientes normotensos e hipertensos submetidos a exodontia de dentes normalmente implantados sob ação do anestésico local cloridrato de prilocaina 3%, com felipressina 0,03UI/ml. Material e Métodos: Foram avaliados 49 pacientes do ambulatório da Disciplina de Cirurgia e Traumatologia Buco-Maxilo-Facial do Curso de Odontologia do Instituto de Ciência e Tecnologia da Universidade Estadual Paulista ‘’Julio de Mesquita Filho” campus de São Jose dos Campos, sendo 30 normotensos e 19 hipertensos que deveriam ter no momento da avaliação inicial pressão sistólica até 160 mmHg e diastólica até 100 mmHg além de estarem sob acompanhamento médico. Os pacientes foram submetidos a exodontia de molares ou pré-molares normalmente implantados, com grau máximo de mobilidade 2, segundo a classificação de Miller. Os parâmetros avaliados foram pressão arterial sistólica, diastolica e frequência cardíaca, por meio de um aparelho digital automático de pulso, nos seguintes períodos: T1 - inicial (5 min antes do início da cirurgia, com o paciente sentado); T2 – pós-anestesia (após 2 min da administração do anestésico); T3 – trans-operatório (a cada 5 min após a aferição em T2 até completar 20 minutos, totalizando 4 mensurações trans-operatórias); T4 – pós-cirurgia ( 5 min após a remoção dos campos cirúrgicos). Resultados: A análise estatística demonstrou que para os parâmetros pressão arterial sistólica (P = 0,959) e pressão arterial diastólica (P = 0,754) não houve diferença estatística significante para estes parâmetros nos diferentes períodos de avaliação. A análise dos valores de frequência cardíaca demonstrou haver diferença estatística (p < 0,05) entre os valores obtidos em T1 nos pacientes hipertensos e T3.3 nos pacientes normotensos...

Objective: this study evaluated hemodynamic variations of normotensive and hypertensive patients undergoing dental extraction under local anesthesia with 3% prilocaine with 0.03 UI/ml felypressin. Material and Methods: Forty-nine patients from the Department of Surgery and Maxillo-facial Traumatology ambulatory were evaluated. Thirty were normotensive and 19 hypertensive; they presented initial systolic blood pressure lower than 160 mmHg and diastolic blood pressure lower than 100 mmHg, besides being under medical supervision. Patients underwent molar or premolar extraction, typically deployed with maximum degree of mobility 2, according to Miller’s classification. The parameters evaluated were systolic and diastolic blood pressures and heart rate, using an automatic digital pulse device, in the following periods: T1 - Initial (5 min before the beginning of surgery, with the patient seated); T2 - post-anesthesia (after 2 min of anesthetic administration); T3 - trans-operative (every 5 min after the measurement T2 to complete 20 min, totaling 4 trans-operative measurements); T4 - after surgery (5 min after removal of the surgical field). Results: statistical analysis showed for the parameters systolic blood pressure (P = 0.959) and diastolic blood pressure (P = 0.754), no statistically significant difference for these parameters in different evaluation periods. The analysis of heart rate values showed statistical difference (p < 0.05) between the values obtained in T1 in hypertensive and normotensive patients in T3.3. Conclusion: it was concluded that the evaluated hemodynamic parameters varied in different periods evaluated in group of normotensive and hypertensive patients, but did not differ significantly.

Immunolocalization of markers for bone formation during guided bone regeneration in osteopenic rats

Objective The aim of this paper was to evaluate the repair of onlay autogenous bone grafts covered or not covered by an expanded polytetrafluoroethylene (e-PTFE) membrane using immunohistochemistry in rats with induced estrogen deficiency. Material and Methods Eighty female rats were randomly divided into two groups: ovariectomized (OVX) and with a simulation of the surgical procedure (SHAM). Each of these groups was again divided into groups with either placement of an autogenous bone graft alone (BG) or an autogenous bone graft associated with an e-PTFE membrane (BGM). Animals were euthanized on days 0, 7, 21, 45, and 60. The specimens were subjected to immunohistochemistry for bone sialoprotein (BSP), osteonectin (ONC), and osteocalcin (OCC). Results All groups (OVX+BG, OVX+BMG, SHAM+BG, and SHAM+BMG) showed greater bone formation, observed between 7 and 21 days, when BSP and ONC staining were more intense. At the 45-day, the bone graft showed direct bonding to the recipient bed in all specimens. The ONC and OCC showed more expressed in granulation tissue, in the membrane groups, independently of estrogen deficiency. Conclusions The expression of bone forming markers was not negatively influenced by estrogen deficiency. However, the markers could be influenced by the presence of the e-PTFE membrane. .

Comparative evaluation of blood pressure monitoring devices / Avaliação comparativa dos equipamentos de aferição da pressão arterial

Objective: This study evaluated the agreement of blood pressure measurements obtained through different auscultatory and oscillometric automated/ semi-automated monitors. Material and Methods: The blood pressure of 30 participants was evaluated by a single calibrated examiner. The measurements were carried out through either auscultatory monitor (mercury column or aneroid) or automated/semiautomated oscillometric pulse monitors. For each participant, 5 min rest was established by sitting on dental chair and the measurements were always carried out on the left arm, at the heart level. Three consecutive measurements were performed with the four monitors in each participant with a minimum time interval of five minutes between each measurement. All monitors were properly calibrated and certified by INMETRO. The results were submitted to intraclass correlation coefficient and Friedman’s analysis of variance. Results: The measurements of systolic blood pressure for both auscultatory and oscillometric methods were similar. The measurements of diastolic blood pressure for auscultatory monitors were similar (p > 0.05); as well as for oscillometric monitors (p > 0.05). However, when auscultatory and oscillometric monitors were compared, there were statistically significant differences in diastolic blood pressure (p < 0.05). Conclusion: It was verified a difference in the results between the auscultatory and oscillometric blood pressure monitors. The systolic blood pressure measurements exhibited similar correlations, while diastolic blood pressure measurements showed different correlations...

Objetivo: Esse estudo avaliou a concordância da aferição da pressão arterial (PA) obtidas em diferentes equipamentos auscultatório e equipamentos digitais oscilométrico. Material e Métodos: A PA de 30 participantes foi avaliada por um único examinador calibrado. As aferições foram realizadas por meio de aparelhos auscultatório de coluna de mercúrio e aneróide e com equipamentos digital oscilométrico, semi automático e automático de pulso. Foi estabelecido para cada participante, repouso mínimo de cinco minutos permanecendo sentados na cadeira odontológica e as mensurações foram realizadas sempre no braço esquerdo, estando o mesmo apoiado ao nível do coração. Foram realizas 3 mensurações consecutivas com os 4 aparelhos em cada participante com tempo mínimo de 5 minutos entre as aferições. Todos os aparelhos estavam devidamente calibrados e certificados pelo INMETRO. Com os resultados foi realizado coeficiente de correlação intraclasses e a análise de variância de Friedman. Resultados: As medidas da pressão arterial sistólica (PAS) para o método auscultatório e para o oscilométrico foram semelhantes entre si. Para as medidas da pressão arterial diastólica (PAD), aparelhos auscultatórios foram semelhantes (p> 0,05); aparelhos oscilométricos foram semelhantes entre si (p > 0,05), porém quando comparados os modelos auscultatório com o oscilométrico ocorreu diferença estatisticamente significante (p < 0,05). Conclusão: Verificou-se diferença nos resultados entre os métodos auscultatórios e oscilométricos de medida da pressão arterial. Ocorreu uma correlação semelhante nas aferições obtidas para PAS e diferentes para PAD...