Detalles de la búsqueda
1.
Stapled α-helical peptide drug development: a potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy.
Proc Natl Acad Sci U S A;
110(36): E3445-54, 2013 Sep 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-23946421
2.
Discovery of Sulanemadlin (ALRN-6924), the First Cell-Permeating, Stabilized α-Helical Peptide in Clinical Development.
J Med Chem;
66(14): 9401-9417, 2023 07 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37439511
3.
STAT6 phosphorylation inhibitors block eotaxin-3 secretion in bronchial epithelial cells.
Bioorg Med Chem;
20(2): 750-8, 2012 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22217933
4.
Antisense oligonucleotide modulation of non-productive alternative splicing upregulates gene expression.
Nat Commun;
11(1): 3501, 2020 07 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32647108
5.
Discovery and characterization of orthosteric and allosteric muscarinic M2 acetylcholine receptor ligands by affinity selection-mass spectrometry.
J Biomol Screen;
11(2): 194-207, 2006 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-16490772
6.
Identification of a small molecule nonpeptide active site beta-secretase inhibitor that displays a nontraditional binding mode for aspartyl proteases.
J Med Chem;
47(25): 6117-9, 2004 Dec 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-15566281
7.
Inhibitors of the lipid phosphatase SHIP2 discovered by high-throughput affinity selection-mass spectrometry screening of combinatorial libraries.
Comb Chem High Throughput Screen;
12(8): 760-71, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19531013
8.
A general technique to rank protein-ligand binding affinities and determine allosteric versus direct binding site competition in compound mixtures.
J Am Chem Soc;
126(47): 15495-503, 2004 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15563178
9.
A reagent-based strategy for the design of large combinatorial libraries: a preliminary experimental validation.
Mol Divers;
7(1): 3-14, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-14768899
Resultados
1 -
9
de 9
1
Próxima >
>>