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1.

Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19.

Hanson, Aimee L; Mulè, Matthew P; Ruffieux, Hélène; Mescia, Federica; Bergamaschi, Laura; Pelly, Victoria S; Turner, Lorinda; Kotagiri, Prasanti; Göttgens, Berthold; Hess, Christoph; Gleadall, Nicholas; Bradley, John R; Nathan, James A; Lyons, Paul A; Drakesmith, Hal; Smith, Kenneth G C.

Nat Immunol; 25(3): 471-482, 2024 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-38429458

2.

Limited oxygen in standard cell culture alters metabolism and function of differentiated cells.

Tan, Joycelyn; Virtue, Sam; Norris, Dougall M; Conway, Olivia J; Yang, Ming; Bidault, Guillaume; Gribben, Christopher; Lugtu, Fatima; Kamzolas, Ioannis; Krycer, James R; Mills, Richard J; Liang, Lu; Pereira, Conceição; Dale, Martin; Shun-Shion, Amber S; Baird, Harry Jm; Horscroft, James A; Sowton, Alice P; Ma, Marcella; Carobbio, Stefania; Petsalaki, Evangelia; Murray, Andrew J; Gershlick, David C; Nathan, James A; Hudson, James E; Vallier, Ludovic; Fisher-Wellman, Kelsey H; Frezza, Christian; Vidal-Puig, Antonio; Fazakerley, Daniel J.

EMBO J; 2024 Apr 05.

Artículo en Inglés | MEDLINE | ID: mdl-38580776

3.

Immuno- and constitutive proteasomes do not differ in their abilities to degrade ubiquitinated proteins.

Nathan, James A; Spinnenhirn, Valentina; Schmidtke, Gunter; Basler, Michael; Groettrup, Marcus; Goldberg, Alfred L.

Cell; 152(5): 1184-94, 2013 Feb 28.

Artículo en Inglés | MEDLINE | ID: mdl-23452861

4.

LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein.

Shilts, Jarrod; Crozier, Thomas W M; Teixeira-Silva, Ana; Gabaev, Ildar; Gerber, Pehuén Pereyra; Greenwood, Edward J D; Watson, Samuel James; Ortmann, Brian M; Gawden-Bone, Christian M; Pauzaite, Tekle; Hoffmann, Markus; Nathan, James A; Pöhlmann, Stefan; Matheson, Nicholas J; Lehner, Paul J; Wright, Gavin J.

PLoS Biol; 21(2): e3001959, 2023 02.

Artículo en Inglés | MEDLINE | ID: mdl-36735681

5.

Nitrosylation rewires metabolism.

Nathan, James A.

Nat Chem Biol; 19(3): 253-254, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36266350

6.

MARCH6 and TRC8 facilitate the quality control of cytosolic and tail-anchored proteins.

Stefanovic-Barrett, Sandra; Dickson, Anna S; Burr, Stephen P; Williamson, James C; Lobb, Ian T; van den Boomen, Dick Jh; Lehner, Paul J; Nathan, James A.

EMBO Rep; 19(5)2018 05.

Artículo en Inglés | MEDLINE | ID: mdl-29519897

7.

FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1.

Scholz, Carsten C; Rodriguez, Javier; Pickel, Christina; Burr, Stephen; Fabrizio, Jacqueline-Alba; Nolan, Karen A; Spielmann, Patrick; Cavadas, Miguel A S; Crifo, Bianca; Halligan, Doug N; Nathan, James A; Peet, Daniel J; Wenger, Roland H; Von Kriegsheim, Alex; Cummins, Eoin P; Taylor, Cormac T.

PLoS Biol; 14(1): e1002347, 2016 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-26752685

8.

Squalene and cholesterol in the balance at the ER membrane.

Nathan, James A.

Proc Natl Acad Sci U S A; 117(15): 8228-8230, 2020 04 14.

Artículo en Inglés | MEDLINE | ID: mdl-32238557

9.

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

Nathan, James A; Kim, Hyoung Tae; Ting, Lily; Gygi, Steven P; Goldberg, Alfred L.

EMBO J; 32(4): 552-65, 2013 Feb 20.

Artículo en Inglés | MEDLINE | ID: mdl-23314748

10.

The recognition of ubiquitinated proteins by the proteasome.

Grice, Guinevere L; Nathan, James A.

Cell Mol Life Sci; 73(18): 3497-506, 2016 09.

Artículo en Inglés | MEDLINE | ID: mdl-27137187

11.

TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I.

van den Boomen, Dick J H; Timms, Richard T; Grice, Guinevere L; Stagg, Helen R; Skødt, Karsten; Dougan, Gordon; Nathan, James A; Lehner, Paul J.

Proc Natl Acad Sci U S A; 111(31): 11425-30, 2014 Aug 05.

Artículo en Inglés | MEDLINE | ID: mdl-25030448

12.

Different opinion on the reported role of Poldip2 and ACSM1 in a mammalian lipoic acid salvage pathway controlling HIF-1 activation.

Bailey, Peter S J; Hiltunen, J Kalervo; Dieckmann, Carol L; Kastaniotis, Alexander J; Nathan, James A.

Proc Natl Acad Sci U S A; 115(32): E7458-E7459, 2018 08 07.

Artículo en Inglés | MEDLINE | ID: mdl-30042217

13.

Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry.

Deriziotis, Pelagia; André, Ralph; Smith, David M; Goold, Rob; Kinghorn, Kerri J; Kristiansen, Mark; Nathan, James A; Rosenzweig, Rina; Krutauz, Dasha; Glickman, Michael H; Collinge, John; Goldberg, Alfred L; Tabrizi, Sarah J.

EMBO J; 30(15): 3065-77, 2011 Jul 08.

Artículo en Inglés | MEDLINE | ID: mdl-21743439

14.

The ATP costs and time required to degrade ubiquitinated proteins by the 26 S proteasome.

Peth, Andreas; Nathan, James A; Goldberg, Alfred L.

J Biol Chem; 288(40): 29215-22, 2013 Oct 04.

Artículo en Inglés | MEDLINE | ID: mdl-23965995

15.

Characterizing OXPHOS inhibitor-mediated alleviation of hypoxia using high-throughput live cell-imaging.

Beerkens, Anne P M; Boreel, Daan F; Nathan, James A; Neuzil, Jiri; Cheng, Gang; Kalyanaraman, Balaraman; Hardy, Micael; Adema, Gosse J; Heskamp, Sandra; Span, Paul N; Bussink, Johan.

Cancer Metab; 12(1): 13, 2024 May 03.

Artículo en Inglés | MEDLINE | ID: mdl-38702787

16.

Cigarette smoke preferentially induces full length ACE2 expression in differentiated primary human airway cultures but does not alter the efficiency of cellular SARS-CoV-2 infection.

Porter, Linsey M; Guo, Wenrui; Crozier, Thomas Wm; Greenwood, Edward Jd; Ortmann, Brian; Kottmann, Daniel; Nathan, James A; Mahadeva, Ravindra; Lehner, Paul J; McCaughan, Frank.

Heliyon; 9(3): e14383, 2023 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-36938474

17.

A HIF independent oxygen-sensitive pathway for controlling cholesterol synthesis.

Dickson, Anna S; Pauzaite, Tekle; Arnaiz, Esther; Ortmann, Brian M; West, James A; Volkmar, Norbert; Martinelli, Anthony W; Li, Zhaoqi; Wit, Niek; Vitkup, Dennis; Kaser, Arthur; Lehner, Paul J; Nathan, James A.

Nat Commun; 14(1): 4816, 2023 08 09.

Artículo en Inglés | MEDLINE | ID: mdl-37558666

18.

A histone deacetylase 3 and mitochondrial complex I axis regulates toxic formaldehyde production.

Wit, Niek; Gogola, Ewa; West, James A; Vornbäumen, Tristan; Seear, Rachel V; Bailey, Peter S J; Burgos-Barragan, Guillermo; Wang, Meng; Krawczyk, Patrycja; Huberts, Daphne H E W; Gergely, Fanni; Matheson, Nicholas J; Kaser, Arthur; Nathan, James A; Patel, Ketan J.

Sci Adv; 9(20): eadg2235, 2023 05 19.

Artículo en Inglés | MEDLINE | ID: mdl-37196082

19.

Glutarate regulates T cell metabolism and anti-tumour immunity.

Minogue, Eleanor; Cunha, Pedro P; Wadsworth, Brennan J; Grice, Guinevere L; Sah-Teli, Shiv K; Hughes, Rob; Bargiela, David; Quaranta, Alessandro; Zurita, Javier; Antrobus, Robin; Velica, Pedro; Barbieri, Laura; Wheelock, Craig E; Koivunen, Peppi; Nathan, James A; Foskolou, Iosifina P; Johnson, Randall S.

Nat Metab; 5(10): 1747-1764, 2023 10.

Artículo en Inglés | MEDLINE | ID: mdl-37605057

20.

Stabilization of an E3 ligase-E2-ubiquitin complex increases cell surface MHC class I expression.

Duncan, Lidia M; Nathan, James A; Lehner, Paul J.

J Immunol; 184(12): 6978-85, 2010 Jun 15.

Artículo en Inglés | MEDLINE | ID: mdl-20483773

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