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1.

Metabolic dysfunction-associated steatotic liver disease: Update and impact of new nomenclature on the American Association for the Study of Liver Diseases practice guidance on nonalcoholic fatty liver disease.

Kanwal, Fasiha; Neuschwander-Tetri, Brent A; Loomba, Rohit; Rinella, Mary E.

Hepatology; 79(5): 1212-1219, 2024 May 01.

Artículo en Inglés | MEDLINE | ID: mdl-38445559

2.

PNPLA3 rs738409, age, diabetes, sex, and advanced fibrosis jointly contribute to the risk of major adverse liver outcomes in metabolic-associated steatotic liver disease.

Chalasani, Naga; Vilar-Gomez, Eduardo; Loomba, Rohit; Yates, Katherine P; Diehl, Anna Mae; Neuschwander-Tetri, Brent A; Dasarathy, Srinivasan; Kowdley, Kris V; Terrault, Norah; Wilson, Laura A; Tonascia, James; Sanyal, Arun.

Hepatology; 2024 Apr 23.

Artículo en Inglés | MEDLINE | ID: mdl-38652636

3.

Prospective Study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease.

Sanyal, Arun J; Van Natta, Mark L; Clark, Jeanne; Neuschwander-Tetri, Brent A; Diehl, AnnaMae; Dasarathy, Srinivasan; Loomba, Rohit; Chalasani, Naga; Kowdley, Kris; Hameed, Bilal; Wilson, Laura A; Yates, Katherine P; Belt, Patricia; Lazo, Mariana; Kleiner, David E; Behling, Cynthia; Tonascia, James.

N Engl J Med; 385(17): 1559-1569, 2021 10 21.

Artículo en Inglés | MEDLINE | ID: mdl-34670043

4.

Cenicriviroc Lacked Efficacy to Treat Liver Fibrosis in Nonalcoholic Steatohepatitis: AURORA Phase III Randomized Study.

Anstee, Quentin M; Neuschwander-Tetri, Brent A; Wai-Sun Wong, Vincent; Abdelmalek, Manal F; Rodriguez-Araujo, Gerardo; Landgren, Henrik; Park, Grace S; Bedossa, Pierre; Alkhouri, Naim; Tacke, Frank; Sanyal, Arun J.

Clin Gastroenterol Hepatol; 22(1): 124-134.e1, 2024 01.

Artículo en Inglés | MEDLINE | ID: mdl-37061109

5.

Fibrosis Progression Rate in Biopsy-Proven Nonalcoholic Fatty Liver Disease Among People With Diabetes Versus People Without Diabetes: A Multicenter Study.

Huang, Daniel Q; Wilson, Laura A; Behling, Cynthia; Kleiner, David E; Kowdley, Kris V; Dasarathy, Srinivasan; Amangurbanova, Maral; Terrault, Norah A; Diehl, Anna Mae; Chalasani, Naga; Neuschwander-Tetri, Brent A; Sanyal, Arun J; Tonascia, James; Loomba, Rohit.

Gastroenterology; 165(2): 463-472.e5, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37127100

6.

Pegbelfermin in Patients With Nonalcoholic Steatohepatitis and Stage 3 Fibrosis (FALCON 1): A Randomized Phase 2b Study.

Loomba, Rohit; Sanyal, Arun J; Nakajima, Atsushi; Neuschwander-Tetri, Brent A; Goodman, Zachary D; Harrison, Stephen A; Lawitz, Eric J; Gunn, Nadege; Imajo, Kento; Ravendhran, Natarajan; Akahane, Takemi; Boone, Bradly; Yamaguchi, Masayuki; Chatterjee, Arkendu; Tirucherai, Giridhar S; Shevell, Diane E; Du, Shuyan; Charles, Edgar D; Abdelmalek, Manal F.

Clin Gastroenterol Hepatol; 22(1): 102-112.e9, 2024 01.

Artículo en Inglés | MEDLINE | ID: mdl-37088457

7.

Pegbelfermin in Patients With Nonalcoholic Steatohepatitis and Compensated Cirrhosis (FALCON 2): A Randomized Phase 2b Study.

Abdelmalek, Manal F; Sanyal, Arun J; Nakajima, Atsushi; Neuschwander-Tetri, Brent A; Goodman, Zachary D; Lawitz, Eric J; Harrison, Stephen A; Jacobson, Ira M; Imajo, Kento; Gunn, Nadege; Halegoua-DeMarzio, Dina; Akahane, Takemi; Boone, Bradly; Yamaguchi, Masayuki; Chatterjee, Arkendu; Tirucherai, Giridhar S; Shevell, Diane E; Du, Shuyan; Charles, Edgar D; Loomba, Rohit.

Clin Gastroenterol Hepatol; 22(1): 113-123.e9, 2024 01.

Artículo en Inglés | MEDLINE | ID: mdl-37088458

8.

High concordance between nonalcoholic fatty liver disease and metabolic dysfunction associated steatotic liver disease in the TARGET-NASH real world cohort.

Barritt, A Sidney; Yu, Feng; Mospan, Andrea R; Newsome, Philip; Roden, Michael; Morris, Heather L; Loomba, Rohit; Neuschwander-Tetri, Brent A.

Am J Gastroenterol; 2024 Apr 08.

Artículo en Inglés | MEDLINE | ID: mdl-38587293

9.

Defining the serum proteomic signature of hepatic steatosis, inflammation, ballooning and fibrosis in non-alcoholic fatty liver disease.

Sanyal, Arun J; Williams, Stephen A; Lavine, Joel E; Neuschwander-Tetri, Brent A; Alexander, Leigh; Ostroff, Rachel; Biegel, Hannah; Kowdley, Kris V; Chalasani, Naga; Dasarathy, Srinivasan; Diehl, Anna Mae; Loomba, Rohit; Hameed, Bilal; Behling, Cynthia; Kleiner, David E; Karpen, Saul J; Williams, Jessica; Jia, Yi; Yates, Katherine P; Tonascia, James.

J Hepatol; 78(4): 693-703, 2023 04.

Artículo en Inglés | MEDLINE | ID: mdl-36528237

10.

A phase I/II study of ARO-HSD, an RNA interference therapeutic, for the treatment of non-alcoholic steatohepatitis.

Mak, Lung-Yi; Gane, Ed; Schwabe, Christian; Yoon, Ki Tae; Heo, Jeong; Scott, Russell; Lee, Jeong-Hoon; Lee, Jung Il; Kweon, Young Oh; Weltman, Martin; Harrison, Stephen A; Neuschwander-Tetri, Brent A; Cusi, Kenneth; Loomba, Rohit; Given, Bruce D; Christianson, Dawn R; Garcia-Medel, Eric; Yi, Min; Hamilton, James; Yuen, Man-Fung.

J Hepatol; 78(4): 684-692, 2023 04.

Artículo en Inglés | MEDLINE | ID: mdl-36513186

11.

Changes in abdominal adipose tissue depots assessed by MRI correlate with hepatic histologic improvement in non-alcoholic steatohepatitis.

Shen, Wei; Middleton, Michael S; Cunha, Guilherme M; Delgado, Timoteo I; Wolfson, Tanya; Gamst, Anthony; Fowler, Kathryn J; Alazraki, Adina; Trout, Andrew T; Ohliger, Michael A; Shah, Shetal N; Bashir, Mustafa R; Kleiner, David E; Loomba, Rohit; Neuschwander-Tetri, Brent A; Sanyal, Arun J; Zhou, Jane; Sirlin, Claude B; Lavine, Joel E.

J Hepatol; 78(2): 238-246, 2023 02.

Artículo en Inglés | MEDLINE | ID: mdl-36368598

12.

Inhibition of integrin binding to ligand arg-gly-asp motif induces AKT-mediated cellular senescence in hepatic stellate cells.

Kitsugi, Kensuke; Noritake, Hidenao; Matsumoto, Moe; Hanaoka, Tomohiko; Umemura, Masahiro; Yamashita, Maho; Takatori, Shingo; Ito, Jun; Ohta, Kazuyoshi; Chida, Takeshi; Ulmasov, Barbara; Neuschwander-Tetri, Brent A; Suda, Takafumi; Kawata, Kazuhito.

Mol Cell Biochem; 2023 Oct 30.

Artículo en Inglés | MEDLINE | ID: mdl-37902885

13.

EDP-305 in patients with NASH: A phase II double-blind placebo-controlled dose-ranging study.

Ratziu, Vlad; Rinella, Mary E; Neuschwander-Tetri, Brent A; Lawitz, Eric; Denham, Douglas; Kayali, Zeid; Sheikh, Aasim; Kowdley, Kris V; Desta, Taddese; Elkhashab, Magdy; DeGrauw, Jeffery; Goodwin, Bryan; Ahmad, Alaa; Adda, Nathalie.

J Hepatol; 76(3): 506-517, 2022 03.

Artículo en Inglés | MEDLINE | ID: mdl-34740705

14.

TVB-2640 (FASN Inhibitor) for the Treatment of Nonalcoholic Steatohepatitis: FASCINATE-1, a Randomized, Placebo-Controlled Phase 2a Trial.

Loomba, Rohit; Mohseni, Rizwana; Lucas, K Jean; Gutierrez, Julio A; Perry, Robert G; Trotter, James F; Rahimi, Robert S; Harrison, Stephen A; Ajmera, Veeral; Wayne, Jeffrey D; O'Farrell, Marie; McCulloch, William; Grimmer, Katharine; Rinella, Mary; Wai-Sun Wong, Vincent; Ratziu, Vlad; Gores, Gregory J; Neuschwander-Tetri, Brent A; Kemble, George.

Gastroenterology; 161(5): 1475-1486, 2021 11.

Artículo en Inglés | MEDLINE | ID: mdl-34310978

15.

NAFLD: Reporting Histologic Findings in Clinical Practice.

Brunt, Elizabeth M; Kleiner, David E; Carpenter, Danielle H; Rinella, Mary; Harrison, Stephen A; Loomba, Rohit; Younossi, Zobair; Neuschwander-Tetri, Brent A; Sanyal, Arun J.

Hepatology; 73(5): 2028-2038, 2021 05.

Artículo en Inglés | MEDLINE | ID: mdl-33111374

16.

Therapeutic Landscape for NAFLD in 2020.

Neuschwander-Tetri, Brent A.

Gastroenterology; 158(7): 1984-1998.e3, 2020 05.

Artículo en Inglés | MEDLINE | ID: mdl-32061596

17.

Multicenter Validation of Association Between Decline in MRI-PDFF and Histologic Response in NASH.

Loomba, Rohit; Neuschwander-Tetri, Brent A; Sanyal, Arun; Chalasani, Naga; Diehl, Anna Mae; Terrault, Norah; Kowdley, Kris; Dasarathy, Srinivasan; Kleiner, David; Behling, Cynthia; Lavine, Joel; Van Natta, Mark; Middleton, Michael; Tonascia, James; Sirlin, Claude.

Hepatology; 72(4): 1219-1229, 2020 10.

Artículo en Inglés | MEDLINE | ID: mdl-31965579

18.

Opioid Use Is More Common in Nonalcoholic Fatty Liver Disease Patients with Cirrhosis, Higher BMI, and Psychiatric Disease.

Moon, Andrew M; Watkins, Stephanie E; Lok, Anna S; Firpi-Morell, Roberto J; Trinh, Huy Ngoc; Kupec, Justin T; Schoen, Cheryl; Neuschwander-Tetri, Brent A; Barritt, A Sidney.

Dig Dis; 39(3): 247-257, 2021.

Artículo en Inglés | MEDLINE | ID: mdl-32836224

19.

Impact of obeticholic acid on the lipoprotein profile in patients with non-alcoholic steatohepatitis.

Siddiqui, Mohammad Shadab; Van Natta, Mark L; Connelly, Margery A; Vuppalanchi, Raj; Neuschwander-Tetri, Brent A; Tonascia, James; Guy, Cynthia; Loomba, Rohit; Dasarathy, Srinivasan; Wattacheril, Julia; Chalasani, Naga; Sanyal, Arun J.

J Hepatol; 72(1): 25-33, 2020 01.

Artículo en Inglés | MEDLINE | ID: mdl-31634532

20.

Pegbelfermin (BMS-986036), a PEGylated fibroblast growth factor 21 analogue, in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 2a trial.

Sanyal, Arun; Charles, Edgar D; Neuschwander-Tetri, Brent A; Loomba, Rohit; Harrison, Stephen A; Abdelmalek, Manal F; Lawitz, Eric J; Halegoua-DeMarzio, Dina; Kundu, Sudeep; Noviello, Stephanie; Luo, Yi; Christian, Rose.

Lancet; 392(10165): 2705-2717, 2019 12 22.

Artículo en Inglés | MEDLINE | ID: mdl-30554783

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