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1.

Elucidation of the Molecular Mechanism Driving Duplication of the HIV-1 PTAP Late Domain.

Martins, Angelica N; Waheed, Abdul A; Ablan, Sherimay D; Huang, Wei; Newton, Alicia; Petropoulos, Christos J; Brindeiro, Rodrigo D M; Freed, Eric O.

J Virol; 90(2): 768-79, 2016 01 15.

Artículo en Inglés | MEDLINE | ID: mdl-26512081

2.

The molecular basis of drug resistance against hepatitis C virus NS3/4A protease inhibitors.

Romano, Keith P; Ali, Akbar; Aydin, Cihan; Soumana, Djade; Ozen, Aysegül; Deveau, Laura M; Silver, Casey; Cao, Hong; Newton, Alicia; Petropoulos, Christos J; Huang, Wei; Schiffer, Celia A.

PLoS Pathog; 8(7): e1002832, 2012.

Artículo en Inglés | MEDLINE | ID: mdl-22910833

3.

HER3, p95HER2, and HER2 protein expression levels define multiple subtypes of HER2-positive metastatic breast cancer.

Lipton, Allan; Goodman, Laurie; Leitzel, Kim; Cook, Jennifer; Sperinde, Jeff; Haddad, Mojgan; Köstler, Wolfgang J; Huang, Weidong; Weidler, Jodi M; Ali, Suhail; Newton, Alicia; Fuchs, Eva-Marie; Paquet, Agnes; Singer, Christian F; Horvat, Reinhard; Jin, Xueguang; Banerjee, Joyee; Mukherjee, Ali; Tan, Yuping; Shi, Yining; Chenna, Ahmed; Larson, Jeff; Lie, Yolanda; Sherwood, Thomas; Petropoulos, Christos J; Williams, Stephen; Winslow, John; Parry, Gordon; Bates, Michael.

Breast Cancer Res Treat; 141(1): 43-53, 2013 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-23959396

4.

Discovery of Quinoxaline-Based P1-P3 Macrocyclic NS3/4A Protease Inhibitors with Potent Activity against Drug-Resistant Hepatitis C Virus Variants.

Nageswara Rao, Desaboini; Zephyr, Jacqueto; Henes, Mina; Chan, Elise T; Matthew, Ashley N; Hedger, Adam K; Conway, Hasahn L; Saeed, Mohsan; Newton, Alicia; Petropoulos, Christos J; Huang, Wei; Kurt Yilmaz, Nese; Schiffer, Celia A; Ali, Akbar.

J Med Chem; 64(16): 11972-11989, 2021 08 26.

Artículo en Inglés | MEDLINE | ID: mdl-34405680

5.

Fear of Change and the Courage to Overcome.

Newton, Alicia.

Nurs Womens Health; 23(5): 459-460, 2019 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-31445989

6.

Drug resistance emergence in macaques administered cabotegravir long-acting for pre-exposure prophylaxis during acute SHIV infection.

Radzio-Basu, Jessica; Council, Olivia; Cong, Mian-Er; Ruone, Susan; Newton, Alicia; Wei, Xierong; Mitchell, James; Ellis, Shanon; Petropoulos, Christos J; Huang, Wei; Spreen, William; Heneine, Walid; García-Lerma, J Gerardo.

Nat Commun; 10(1): 2005, 2019 05 01.

Artículo en Inglés | MEDLINE | ID: mdl-31043606

7.

Antibodies neutralizing hepsin protease activity do not impact cell growth but inhibit invasion of prostate and ovarian tumor cells in culture.

Xuan, Jian-Ai; Schneider, Doug; Toy, Pam; Lin, Rick; Newton, Alicia; Zhu, Ying; Finster, Silke; Vogel, David; Mintzer, Bob; Dinter, Harald; Light, David; Parry, Renate; Polokoff, Mark; Whitlow, Marc; Wu, Qingyu; Parry, Gordon.

Cancer Res; 66(7): 3611-9, 2006 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-16585186

8.

Molecular Mechanism of Resistance in a Clinically Significant Double-Mutant Variant of HCV NS3/4A Protease.

Matthew, Ashley N; Leidner, Florian; Newton, Alicia; Petropoulos, Christos J; Huang, Wei; Ali, Akbar; KurtYilmaz, Nese; Schiffer, Celia A.

Structure; 26(10): 1360-1372.e5, 2018 10 02.

Artículo en Inglés | MEDLINE | ID: mdl-30146168

9.

Quinoxaline-Based Linear HCV NS3/4A Protease Inhibitors Exhibit Potent Activity against Drug Resistant Variants.

Rusere, Linah N; Matthew, Ashley N; Lockbaum, Gordon J; Jahangir, Muhammad; Newton, Alicia; Petropoulos, Christos J; Huang, Wei; Kurt Yilmaz, Nese; Schiffer, Celia A; Ali, Akbar.

ACS Med Chem Lett; 9(7): 691-696, 2018 Jul 12.

Artículo en Inglés | MEDLINE | ID: mdl-30034602

10.

Identification of a novel prostate tumor target, mindin/RG-1, for antibody-based radiotherapy of prostate cancer.

Parry, Renate; Schneider, Doug; Hudson, Debra; Parkes, Debbie; Xuan, Jian-Ai; Newton, Alicia; Toy, Pam; Lin, Rick; Harkins, Rick; Alicke, Bruno; Biroc, Sandra; Kretschmer, Peter J; Halks-Miller, Meredith; Klocker, Helmut; Zhu, Ying; Larsen, Brent; Cobb, Ronald R; Bringmann, Peter; Roth, Georg; Lewis, Jason S; Dinter, Harald; Parry, Gordon.

Cancer Res; 65(18): 8397-405, 2005 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-16166318

11.

Hepatitis C Virus NS3/4A Protease Inhibitors Incorporating Flexible P2 Quinoxalines Target Drug Resistant Viral Variants.

Matthew, Ashley N; Zephyr, Jacqueto; Hill, Caitlin J; Jahangir, Muhammad; Newton, Alicia; Petropoulos, Christos J; Huang, Wei; Kurt-Yilmaz, Nese; Schiffer, Celia A; Ali, Akbar.

J Med Chem; 60(13): 5699-5716, 2017 07 13.

Artículo en Inglés | MEDLINE | ID: mdl-28594175

12.

Tab2, a novel recombinant polypeptide tag offering sensitive and specific protein detection and reliable affinity purification.

Crusius, Kerstin; Finster, Silke; McClary, John; Xia, Wei; Larsen, Brent; Schneider, Douglas; Lu, Hong-Tao; Biancalana, Sara; Xuan, Jian-Ai; Newton, Alicia; Allen, Debbie; Bringmann, Peter; Cobb, Ronald R.

Gene; 380(2): 111-9, 2006 Oct 01.

Artículo en Inglés | MEDLINE | ID: mdl-16879932

13.

Evaluating the role of macrocycles in the susceptibility of hepatitis C virus NS3/4A protease inhibitors to drug resistance.

Ali, Akbar; Aydin, Cihan; Gildemeister, Reinhold; Romano, Keith P; Cao, Hong; Ozen, Aysegül; Soumana, Djade; Newton, Alicia; Petropoulos, Christos J; Huang, Wei; Schiffer, Celia A.

ACS Chem Biol; 8(7): 1469-78, 2013 Jul 19.

Artículo en Inglés | MEDLINE | ID: mdl-23594083

14.

Profiling the HER3/PI3K pathway in breast tumors using proximity-directed assays identifies correlations between protein complexes and phosphoproteins.

Mukherjee, Ali; Badal, Youssouf; Nguyen, Xuan-Thao; Miller, Johanna; Chenna, Ahmed; Tahir, Hasan; Newton, Alicia; Parry, Gordon; Williams, Stephen.

PLoS One; 6(1): e16443, 2011 Jan 28.

Artículo en Inglés | MEDLINE | ID: mdl-21297994

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