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1.

The Pancreatic ß-Cell: A Bioenergetic Perspective.

Nicholls, David G.

Physiol Rev; 96(4): 1385-447, 2016 10.

Artículo en Inglés | MEDLINE | ID: mdl-27582250

2.

Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements.

Mookerjee, Shona A; Gerencser, Akos A; Nicholls, David G; Brand, Martin D.

J Biol Chem; 292(17): 7189-7207, 2017 04 28.

Artículo en Inglés | MEDLINE | ID: mdl-28270511

3.

The contributions of respiration and glycolysis to extracellular acid production.

Mookerjee, Shona A; Goncalves, Renata L S; Gerencser, Akos A; Nicholls, David G; Brand, Martin D.

Biochim Biophys Acta; 1847(2): 171-181, 2015 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-25449966

4.

Calcium modulation of exocytosis-linked plasma membrane potential oscillations in INS-1 832/13 cells.

Gerencser, Akos A; Mulder, Hindrik; Nicholls, David G.

Biochem J; 471(1): 111-22, 2015 Oct 01.

Artículo en Inglés | MEDLINE | ID: mdl-26243883

5.

Chronic high glucose and pyruvate levels differentially affect mitochondrial bioenergetics and fuel-stimulated insulin secretion from clonal INS-1 832/13 cells.

Göhring, Isabel; Sharoyko, Vladimir V; Malmgren, Siri; Andersson, Lotta E; Spégel, Peter; Nicholls, David G; Mulder, Hindrik.

J Biol Chem; 289(6): 3786-98, 2014 Feb 07.

Artículo en Inglés | MEDLINE | ID: mdl-24356960

6.

Mitochondrial bioenergetics and neuronal survival modelled in primary neuronal culture and isolated nerve terminals.

Nicholls, David G; Brand, Martin D; Gerencser, Akos A.

J Bioenerg Biomembr; 47(1-2): 63-74, 2015 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-25172197

7.

The 'mitoflash' probe cpYFP does not respond to superoxide.

Schwarzländer, Markus; Wagner, Stephan; Ermakova, Yulia G; Belousov, Vsevolod V; Radi, Rafael; Beckman, Joseph S; Buettner, Garry R; Demaurex, Nicolas; Duchen, Michael R; Forman, Henry J; Fricker, Mark D; Gems, David; Halestrap, Andrew P; Halliwell, Barry; Jakob, Ursula; Johnston, Iain G; Jones, Nick S; Logan, David C; Morgan, Bruce; Müller, Florian L; Nicholls, David G; Remington, S James; Schumacker, Paul T; Winterbourn, Christine C; Sweetlove, Lee J; Meyer, Andreas J; Dick, Tobias P; Murphy, Michael P.

Nature; 514(7523): E12-4, 2014 Oct 23.

Artículo en Inglés | MEDLINE | ID: mdl-25341790

8.

Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements.

Mookerjee, Shona A; Gerencser, Akos A; Nicholls, David G; Brand, Martin D.

J Biol Chem; 293(32): 12649-12652, 2018 08 10.

Artículo en Inglés | MEDLINE | ID: mdl-30097494

9.

No consistent bioenergetic defects in presynaptic nerve terminals isolated from mouse models of Alzheimer's disease.

Choi, Sung W; Gerencser, Akos A; Ng, Ryan; Flynn, James M; Melov, Simon; Danielson, Steven R; Gibson, Bradford W; Nicholls, David G; Bredesen, Dale E; Brand, Martin D.

J Neurosci; 32(47): 16775-84, 2012 Nov 21.

Artículo en Inglés | MEDLINE | ID: mdl-23175831

10.

Plasma membrane potential oscillations in insulin secreting Ins-1 832/13 cells do not require glycolysis and are not initiated by fluctuations in mitochondrial bioenergetics.

Goehring, Isabel; Gerencser, Akos A; Schmidt, Sara; Brand, Martin D; Mulder, Hindrik; Nicholls, David G.

J Biol Chem; 287(19): 15706-17, 2012 May 04.

Artículo en Inglés | MEDLINE | ID: mdl-22418435

11.

Fifty years on: How we uncovered the unique bioenergetics of brown adipose tissue.

Nicholls, David G.

Acta Physiol (Oxf); 237(4): e13938, 2023 04.

Artículo en Inglés | MEDLINE | ID: mdl-36692160

12.

A critical assessment of the role of creatine in brown adipose tissue thermogenesis.

Nicholls, David G; Brand, Martin D.

Nat Metab; 5(1): 21-28, 2023 01.

Artículo en Inglés | MEDLINE | ID: mdl-36624158

13.

Intrinsic bioenergetic properties and stress sensitivity of dopaminergic synaptosomes.

Choi, Sung W; Gerencser, Akos A; Lee, Donna W; Rajagopalan, Subramanian; Nicholls, David G; Andersen, Julie K; Brand, Martin D.

J Neurosci; 31(12): 4524-34, 2011 Mar 23.

Artículo en Inglés | MEDLINE | ID: mdl-21430153

14.

Quantitative measurement of mitochondrial membrane potential in cultured cells: calcium-induced de- and hyperpolarization of neuronal mitochondria.

Gerencser, Akos A; Chinopoulos, Christos; Birket, Matthew J; Jastroch, Martin; Vitelli, Cathy; Nicholls, David G; Brand, Martin D.

J Physiol; 590(12): 2845-71, 2012 Jun 15.

Artículo en Inglés | MEDLINE | ID: mdl-22495585

15.

Assessing mitochondrial dysfunction in cells.

Brand, Martin D; Nicholls, David G.

Biochem J; 435(2): 297-312, 2011 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-21726199

16.

Mitochondrial proton leaks and uncoupling proteins.

Nicholls, David G.

Biochim Biophys Acta Bioenerg; 1862(7): 148428, 2021 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-33798544

17.

Tight coupling between glucose and mitochondrial metabolism in clonal beta-cells is required for robust insulin secretion.

Malmgren, Siri; Nicholls, David G; Taneera, Jalal; Bacos, Karl; Koeck, Thomas; Tamaddon, Ashkan; Wibom, Rolf; Groop, Leif; Ling, Charlotte; Mulder, Hindrik; Sharoyko, Vladimir V.

J Biol Chem; 284(47): 32395-404, 2009 Nov 20.

Artículo en Inglés | MEDLINE | ID: mdl-19797055

18.

Mitochondrial calcium function and dysfunction in the central nervous system.

Nicholls, David G.

Biochim Biophys Acta; 1787(11): 1416-24, 2009 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-19298790

19.

Stochastic aspects of transmitter release and bioenergetic dysfunction in isolated nerve terminals.

Nicholls, David G.

Biochem Soc Trans; 38(2): 457-9, 2010 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-20298202

20.

Forty years of Mitchell's proton circuit: From little grey books to little grey cells.

Nicholls, David G.

Biochim Biophys Acta; 1777(7-8): 550-6, 2008.

Artículo en Inglés | MEDLINE | ID: mdl-18423395

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The Pancreatic ß-Cell: A Bioenergetic Perspective.

Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements.

The contributions of respiration and glycolysis to extracellular acid production.

Calcium modulation of exocytosis-linked plasma membrane potential oscillations in INS-1 832/13 cells.

Chronic high glucose and pyruvate levels differentially affect mitochondrial bioenergetics and fuel-stimulated insulin secretion from clonal INS-1 832/13 cells.

Mitochondrial bioenergetics and neuronal survival modelled in primary neuronal culture and isolated nerve terminals.

The 'mitoflash' probe cpYFP does not respond to superoxide.

Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements.

No consistent bioenergetic defects in presynaptic nerve terminals isolated from mouse models of Alzheimer's disease.

Plasma membrane potential oscillations in insulin secreting Ins-1 832/13 cells do not require glycolysis and are not initiated by fluctuations in mitochondrial bioenergetics.

Fifty years on: How we uncovered the unique bioenergetics of brown adipose tissue.

A critical assessment of the role of creatine in brown adipose tissue thermogenesis.

Intrinsic bioenergetic properties and stress sensitivity of dopaminergic synaptosomes.

Quantitative measurement of mitochondrial membrane potential in cultured cells: calcium-induced de- and hyperpolarization of neuronal mitochondria.

Assessing mitochondrial dysfunction in cells.

Mitochondrial proton leaks and uncoupling proteins.

Tight coupling between glucose and mitochondrial metabolism in clonal beta-cells is required for robust insulin secretion.

Mitochondrial calcium function and dysfunction in the central nervous system.

Stochastic aspects of transmitter release and bioenergetic dysfunction in isolated nerve terminals.

Forty years of Mitchell's proton circuit: From little grey books to little grey cells.