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1.

Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy.

Nimmerjahn, Falk; Vidarsson, Gestur; Cragg, Mark S.

Nat Immunol; 24(8): 1244-1255, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37414906

2.

Immunoglobulin G-dependent inhibition of inflammatory bone remodeling requires pattern recognition receptor Dectin-1.

Seeling, Michaela; Pöhnl, Matthias; Kara, Sibel; Horstmann, Nathalie; Riemer, Carolina; Wöhner, Miriam; Liang, Chunguang; Brückner, Christin; Eiring, Patrick; Werner, Anja; Biburger, Markus; Altmann, Leon; Schneider, Martin; Amon, Lukas; Lehmann, Christian H K; Lee, Sooyeon; Kunz, Meik; Dudziak, Diana; Schett, Georg; Bäuerle, Tobias; Lux, Anja; Tuckermann, Jan; Vögtle, Timo; Nieswandt, Bernhardt; Sauer, Markus; Böckmann, Rainer A; Nimmerjahn, Falk.

Immunity; 56(5): 1046-1063.e7, 2023 05 09.

Artículo en Inglés | MEDLINE | ID: mdl-36948194

3.

Immune Monitoring of Trans-endothelial Transport by Kidney-Resident Macrophages.

Stamatiades, Efstathios G; Tremblay, Marie-Eve; Bohm, Mathieu; Crozet, Lucile; Bisht, Kanchan; Kao, Daniela; Coelho, Carolina; Fan, Xiying; Yewdell, William T; Davidson, Anne; Heeger, Peter S; Diebold, Sandra; Nimmerjahn, Falk; Geissmann, Frederic.

Cell; 166(4): 991-1003, 2016 Aug 11.

Artículo en Inglés | MEDLINE | ID: mdl-27477514

4.

Publisher Correction: Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy.

Nimmerjahn, Falk; Vidarsson, Gestur; Cragg, Mark S.

Nat Immunol; 24(11): 1961, 2023 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-37612468

5.

Publisher Correction: Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy.

Nimmerjahn, Falk; Vidarsson, Gestur; Cragg, Mark S.

Nat Immunol; 24(8): 1391, 2023 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-37438614

6.

IgG Fc domains that bind C1q but not effector FcÎ³ receptors delineate the importance of complement-mediated effector functions.

Lee, Chang-Han; Romain, Gabrielle; Yan, Wupeng; Watanabe, Makiko; Charab, Wissam; Todorova, Biliana; Lee, Jiwon; Triplett, Kendra; Donkor, Moses; Lungu, Oana I; Lux, Anja; Marshall, Nicholas; Lindorfer, Margaret A; Goff, Odile Richard-Le; Balbino, Bianca; Kang, Tae Hyun; Tanno, Hidetaka; Delidakis, George; Alford, Corrine; Taylor, Ronald P; Nimmerjahn, Falk; Varadarajan, Navin; Bruhns, Pierre; Zhang, Yan Jessie; Georgiou, George.

Nat Immunol; 18(8): 889-898, 2017 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-28604720

7.

Regulation of autoantibody activity by the IL-23-T_H17 axis determines the onset of autoimmune disease.

Pfeifle, René; Rothe, Tobias; Ipseiz, Natacha; Scherer, Hans U; Culemann, Stephan; Harre, Ulrike; Ackermann, Jochen A; Seefried, Martina; Kleyer, Arnd; Uderhardt, Stefan; Haugg, Benjamin; Hueber, Axel J; Daum, Patrick; Heidkamp, Gordon F; Ge, Changrong; Böhm, Sybille; Lux, Anja; Schuh, Wolfgang; Magorivska, Iryna; Nandakumar, Kutty S; Lönnblom, Erik; Becker, Christoph; Dudziak, Diana; Wuhrer, Manfred; Rombouts, Yoann; Koeleman, Carolien A; Toes, René; Winkler, Thomas H; Holmdahl, Rikard; Herrmann, Martin; Blüml, Stephan; Nimmerjahn, Falk; Schett, Georg; Krönke, Gerhard.

Nat Immunol; 18(1): 104-113, 2017 01.

Artículo en Inglés | MEDLINE | ID: mdl-27820809

8.

Keeping T-he Killers at Bay via FcÎ³RIIb.

Nimmerjahn, Falk.

Immunity; 52(1): 9-11, 2020 01 14.

Artículo en Inglés | MEDLINE | ID: mdl-31951551

9.

Dissection of complement and Fc-receptor-mediated pathomechanisms of autoantibodies to myelin oligodendrocyte glycoprotein.

Mader, Simone; Ho, Samantha; Wong, Hoi Kiu; Baier, Selia; Winklmeier, Stephan; Riemer, Carolina; Rübsamen, Heike; Fernandez, Iris Marti; Gerhards, Ramona; Du, Cuilian; Chuquisana, Omar; Lünemann, Jan D; Lux, Anja; Nimmerjahn, Falk; Bradl, Monika; Kawakami, Naoto; Meinl, Edgar.

Proc Natl Acad Sci U S A; 120(13): e2300648120, 2023 03 28.

Artículo en Inglés | MEDLINE | ID: mdl-36943883

10.

Corrigendum: IgG Fc domains that bind C1q but not effector FcÎ³ receptors delineate the importance of complement-mediated effector functions.

Lee, Chang-Han; Romain, Gabrielle; Yan, Wupeng; Watanabe, Makiko; Charab, Wissam; Todorova, Biliana; Lee, Jiwon; Triplett, Kendra; Donkor, Moses; Lungu, Oana I; Lux, Anja; Marshall, Nicholas; Lindorfer, Margaret A; Goff, Odile Richard-Le; Balbino, Bianca; Kang, Tae Hyun; Tanno, Hidetaka; Delidakis, George; Alford, Corrine; Taylor, Ronald P; Nimmerjahn, Falk; Varadarajan, Navin; Bruhns, Pierre; Zhang, Yan Jessie; Georgiou, George.

Nat Immunol; 18(10): 1173, 2017 09 19.

Artículo en Inglés | MEDLINE | ID: mdl-28926542

11.

Suppression of FcÎ³-receptor-mediated antibody effector function during persistent viral infection.

Yamada, Douglas H; Elsaesser, Heidi; Lux, Anja; Timmerman, John M; Morrison, Sherie L; de la Torre, Juan Carlos; Nimmerjahn, Falk; Brooks, David G.

Immunity; 42(2): 379-390, 2015 Feb 17.

Artículo en Inglés | MEDLINE | ID: mdl-25680277

12.

Toward Understanding How Staphylococcal Protein A Inhibits IgG-Mediated Phagocytosis.

Cruz, Ana Rita; Bentlage, Arthur E H; Blonk, Robin; de Haas, Carla J C; Aerts, Piet C; Scheepmaker, Lisette M; Bouwmeester, Inge G; Lux, Anja; van Strijp, Jos A G; Nimmerjahn, Falk; van Kessel, Kok P M; Vidarsson, Gestur; Rooijakkers, Suzan H M.

J Immunol; 209(6): 1146-1155, 2022 09 15.

Artículo en Inglés | MEDLINE | ID: mdl-36002230

13.

Cell targeting and immunostimulatory properties of a novel FcÎ³-receptor-independent agonistic anti-CD40 antibody in rhesus macaques.

Yan, Xianglei; Ols, Sebastian; Arcoverde Cerveira, Rodrigo; Lenart, Klara; Hellgren, Fredrika; Ye, Kewei; Cagigi, Alberto; Buggert, Marcus; Nimmerjahn, Falk; Falkesgaard Højen, Jesper; Parera, Daniel; Pessara, Ulrich; Fischer, Stephan; Loré, Karin.

Cell Mol Life Sci; 80(7): 189, 2023 Jun 23.

Artículo en Inglés | MEDLINE | ID: mdl-37353664

14.

Immunomodulation with romiplostim as a second-line strategy in primary immune thrombocytopenia: The iROM study.

Schifferli, Alexandra; Rüfer, Axel; Rovo, Alicia; Nimmerjahn, Falk; Cantoni, Nathan; Holbro, Andreas; Favre, Geneviève; Dirks, Jan; Wieland, Anna; Faeth, Heike; Pereira, Renata; Kühne, Thomas.

Br J Haematol; 203(1): 119-130, 2023 10.

Artículo en Inglés | MEDLINE | ID: mdl-37735543

15.

B-cell modulation with anti-CD79b antibodies ameliorates experimental autoimmune encephalitis in mice.

Renner, Kerstin; Neumayer, Sophia; Talke, Yvonne; Buchtler, Simone; Schmidbauer, Kathrin; Nimmerjahn, Falk; Lux, Anja; Winter, Frederike; Salewski, Jan-Nicklas; Mack, Matthias.

Eur J Immunol; 52(4): 656-668, 2022 04.

Artículo en Inglés | MEDLINE | ID: mdl-34962287

16.

Impaired B Cell Expression of the Inhibitory FcÎ³ Receptor IIB in Myasthenia Gravis.

Keller, Christian W; Chuquisana, Omar; Derdelinckx, Judith; Gross, Catharina C; Berger, Klaus; Robinson, James; Nimmerjahn, Falk; Wiendl, Heinz; Willcox, Nick; Lünemann, Jan D.

Ann Neurol; 92(6): 1046-1051, 2022 12.

Artículo en Inglés | MEDLINE | ID: mdl-36094152

17.

Next-generation antibody-based therapies in neurology.

Ruck, Tobias; Nimmerjahn, Falk; Wiendl, Heinz; Lünemann, Jan D.

Brain; 145(4): 1229-1241, 2022 05 24.

Artículo en Inglés | MEDLINE | ID: mdl-34928330

18.

Response to Oswald et al.: ST6Gal1 in plasma is dispensable for IgG sialylation.

Werner, Anja; Nimmerjahn, Falk.

Glycobiology; 32(11): 917-918, 2022 10 31.

Artículo en Inglés | MEDLINE | ID: mdl-36036830

19.

Siglec-15 on Osteoclasts Is Crucial for Bone Erosion in Serum-Transfer Arthritis.

Korn, Marina A; Schmitt, Heike; Angermüller, Sieglinde; Chambers, David; Seeling, Michaela; Lux, Uwe T; Brey, Stefanie; Royzman, Dmytro; Brückner, Christin; Popp, Vanessa; Percivalle, Elena; Bäuerle, Tobias; Zinser, Elisabeth; Winkler, Thomas H; Steinkasserer, Alexander; Nimmerjahn, Falk; Nitschke, Lars.

J Immunol; 205(10): 2595-2605, 2020 11 15.

Artículo en Inglés | MEDLINE | ID: mdl-33020147

20.

Fc-engineering significantly improves the recruitment of immune effector cells by anti-ICAM-1 antibody MSH-TP15 for myeloma therapy.

Klausz, Katja; Cieker, Michael; Kellner, Christian; Rösner, Thies; Otte, Anna; Krohn, Steffen; Lux, Anja; Nimmerjahn, Falk; Valerius, Thomas; Gramatzki, Martin; Peipp, Matthias.

Haematologica; 106(7): 1857-1866, 2021 07 01.

Artículo en Inglés | MEDLINE | ID: mdl-32499243

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Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy.

Immunoglobulin G-dependent inhibition of inflammatory bone remodeling requires pattern recognition receptor Dectin-1.

Immune Monitoring of Trans-endothelial Transport by Kidney-Resident Macrophages.

Publisher Correction: Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy.

Publisher Correction: Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy.

IgG Fc domains that bind C1q but not effector FcÎ³ receptors delineate the importance of complement-mediated effector functions.

Regulation of autoantibody activity by the IL-23-T_H17 axis determines the onset of autoimmune disease.

Keeping T-he Killers at Bay via FcÎ³RIIb.

Dissection of complement and Fc-receptor-mediated pathomechanisms of autoantibodies to myelin oligodendrocyte glycoprotein.

Corrigendum: IgG Fc domains that bind C1q but not effector FcÎ³ receptors delineate the importance of complement-mediated effector functions.

Suppression of FcÎ³-receptor-mediated antibody effector function during persistent viral infection.

Toward Understanding How Staphylococcal Protein A Inhibits IgG-Mediated Phagocytosis.

Cell targeting and immunostimulatory properties of a novel FcÎ³-receptor-independent agonistic anti-CD40 antibody in rhesus macaques.

Immunomodulation with romiplostim as a second-line strategy in primary immune thrombocytopenia: The iROM study.

B-cell modulation with anti-CD79b antibodies ameliorates experimental autoimmune encephalitis in mice.

Impaired B Cell Expression of the Inhibitory FcÎ³ Receptor IIB in Myasthenia Gravis.

Next-generation antibody-based therapies in neurology.

Response to Oswald et al.: ST6Gal1 in plasma is dispensable for IgG sialylation.

Siglec-15 on Osteoclasts Is Crucial for Bone Erosion in Serum-Transfer Arthritis.

Fc-engineering significantly improves the recruitment of immune effector cells by anti-ICAM-1 antibody MSH-TP15 for myeloma therapy.