Disparities in pulmonary function in healthy children across the Indian urban-rural continuum.

RATIONALE: Marked socioeconomic health-care disparities are recognized in India, but lung health inequalities between urban and rural children have not been studied. OBJECTIVES: We investigated whether differences exist in spirometric pulmonary function in healthy children across the Indian urban-rural continuum and compared results with those from Indian children living in the UK. METHODS: Indian children aged 5 to 12 years were recruited from Indian urban, semiurban, and rural schools, and as part of the Size and Lung Function in Children study, London. Anthropometric and spirometric assessments were undertaken. MEASUREMENTS AND MAIN RESULTS: Acceptable spirometric data were obtained from 728 (58% boys) children in India and 311 (50% boys) UK-Indian children. As an entire group, the India-resident children had significantly lower z FEV1 and z FVC than UK-Indian children (P < 0.0005), when expressed using Global Lung Function Initiative-2012 equations. However, when India-resident children were categorized according to residence, there were no differences in z FEV1 and z FVC between Indian-urban and UK-Indian children. There were, however, significant reductions of ∼ 0.5 z scores and 0.9 z scores in both FEV1 and FVC (with no difference in FEV1/FVC) in Indian-semiurban and Indian-rural children, respectively, when compared with Indian-urban children (P < 0.0005). z Body mass index, socioeconomic circumstances, tobacco, and biomass exposure were individually significantly associated with z FEV1 and z FVC (P < 0.0005). CONCLUSIONS: The presence of an urban-rural continuum of lung function within a specific ethnic group emphasizes the impact of environmental factors on lung growth in emerging nations such as India, which must be taken into account when developing ethnic-specific reference values or designing studies to optimize lung health.

Unintentional Child Injury in Rural and Urban Siddlagatta, Karnataka, India: A Community-Based Survey.

INTRODUCTION: Despite Indian children constituting approximately 31.4% of the population aged 0 to 14, a comprehensive exploration of childhood injuries within this demographic remains limited. This study aimed to examine the occurrence of unintentional injuries among children aged six months to 18 years in the Siddlagatta area and assess associated risk factors. METHODOLOGY: A community-based, cross-sectional study on unintentional child injuries was carried out from March 2018 to September 2020 across 11 sites in India. Employing a two-stage cluster sampling method with probability proportionate to size, 2341 urban and rural families were selected from each site. Data on unintentional injuries sustained over the past 12 months were collected using the WHO child injury questionnaire, tailored and validated for the Indian context. RESULTS: The study encompassed 10,335 individuals in households, including 2695 children aged 6 months to 18 years. Among them, 309 children experienced 390 unintentional injuries in the preceding year, excluding minor incidents. A prevalence rate of 11.5% (95% CI: 10.3-12.7) was identified for unintentional injuries among children, excluding minor cases. Falls were the most prevalent injury type (183 cases, 53.8%), while poisoning incidents were the least frequent (one case, 0.2%). More than 50% of incidents occurred within domestic settings. CONCLUSIONS: This study's outcomes underscore the prominence of fall-related injuries across all age groups and genders. Homes and schools emerged as primary settings for these injuries, highlighting the need for targeted preventive measures.

Descriptive Epidemiology of Unintentional Childhood Injuries in India: An ICMR Taskforce Multisite Study.

BACKGROUND: Children 0-14 years constitute about 31.4% of Indian population, among whom the magnitude and risk factors of childhood injuries have not been adequately studied. OBJECTIVE: To study the prevalence of and assess the factors associated with unintentional injuries among children aged 6 month - 18 years in various regions. METHODOLOGY: This multi-centric, cross-sectional, community-based study was conducted at 11 sites across India. States included were Gujarat, Karnataka, Madhya Pradesh, Punjab, Sikkim, Tamil Nadu, Uttarakhand, and West Bengal between March, 2018 and September, 2020. A total of 2341 urban and rural households from each site were selected based on probability proportionate to size. The World Health Organization (WHO) child injury questionnaire adapted to the Indian settings was used after validation. Information on injuries was collected for previous 12 months. Definitions for types (road traffic accidents, falls, burns, poisoning, drowning, animal-related injuries) and severity of injuries was adapted from the WHO study. Information was elicited from parents/primary caregivers. Data were collected electronically, and handled with a management information system. RESULTS: In the 25751 households studied, there were 31020 children aged 6 months-18 years. A total of 1452 children (66.1% males) had 1535 unintentional injuries (excluding minor injuries) had occurred in the preceding one year. The overall prevalence of unintentional injuries excluding minor injuries was 4.7% (95% CI: 4.4-4.9). The commonest type of injury was fall-related (842, 54.8%) and the least common was drowning (3, 0.2%). Injuries in the home environment accounted for more than 50% of cases. CONCLUSIONS: The findings of the study provide inputs for developing a comprehensive child injury prevention policy in the country. Child safe school with age-appropriate measures, a safe home environment, and road safety measures for children should be a three-pronged approach in minimizing the number and the severity of child injuries both in urban and rural areas.

Knowledge, attitudes and prevalence of tobacco use among physicians and dentists in Oman.

Tobacco use among Omani physicians and dentists has not been studied, so we conducted a crossectional survey using a WHO questionnaire to measure prevalence and to learn about smoking practices among this population and about their knowledge and attitudes of the health effects of tobacco use and tobacco control. The 1191 subjects who participated (787 men and 404 women) ranged in age from 24 to 65 years with a mean (SD) of 41.7 (6.8) years for men and 38.1 (6.9) years for women. The prevalence of tobacco use was 16.4% among males and less than 1% among females. Manufactured cigarettes were the most common form of tobacco used (14.7%), followed by smokeless tobacco (2.2%) and waterpipes (1.7%). Tobacco users were significantly less favorable to strict control and policy measures than never tobacco users and had less knowledge of some of the health effects of tobacco use. Tobacco use among physicians and dentists in Oman is lower than in other countries in the region, but remains a cause of concern. Programs and policies should strive to maintain the low level of tobacco use or reduce it further.

Cancer incidence in Oman, 1998-2006.

BACKGROUND: This paper gives a profile of the cancer incidence in Oman for a nine-year period from 1998-2006. METHODS: Data from the population-based national cancer registry were consolidated for the said nine-year period and analyzed. A breakdown of the incidence by year and gender have been given. Age-standardized incidence of common cancers in Oman and their age-specific rates have been tabulated. Further, a graphical comparison between common cancers in Omani men and women have been made with those of other Gulf countries and some developed countries. RESULTS: There were a total of 8,005 (4,224 males and 3,781 females) cases reported and registered in the registry from January 1998 till December 2006 with a male female ratio of 1.1:1. The crude incidence rate was 49.4 per 100,000 males and 45.7 per 100,000 females. The corresponding age-standardized rates were 91.4 and 80.4 per 100,000 in males and females respectively. CONCLUSIONS: Incidence of cancer in Oman is lower than in some Gulf countries and many developed countries. Stomach cancer, non-Hodgkin lymphoma and leukemia are three commonest cancers in males and breast, thyroid and cervical cancers are the most common in females in the nine-year period.

Trends in rectal cancer incidence--Indian scenario.

The objective was to analyse time trends of rectal cancer for the Indian population by gender, year of diagnosis, and age. Published data for Indian registries were obtained from "Cancer Incidence in Five Continents" and /or individual Indian registries for different time periods. Mean annual percentage change (MAPC) in incidence rates for seven Indian registries was computed using relative difference between two time periods (earliest and latest) and estimation of annual percentage change (EAPC) was computed for three registries by log-linear regression model using SAS version 8.1. The age standardized incidence rate (ASR) of rectal cancer during 2004-2006 ranged from 0.0 to 5.0 per 100,000 population with a male preponderance in most Indian registries. Among males, excepting for the Southern cities, all other registries revealed a decreasing trend/no change in the MAPC both in crude incidence rate (CR) and ASR. However, in females, an increase in MAPC in CR was noted in several registries. Statistically significant increase in EAPC in CR was observed in all the three registries ranging from 1.45% to 3.99% in males while in females the increase was 1.13% in Mumbai and 1.76% in Bangalore. Further studies are required to understand these changing trends and factors that operate in the aetiology of rectal cancer in the Indian scenario. Higher incidence in males indicates the need for greater attention to understand the causes of gender disparities.