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1.

A coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice.

Mehrotra, Shikhar; Al-Khami, Amir A; Klarquist, Jared; Husain, Shahid; Naga, Osama; Eby, Jonathan M; Murali, Anuradha K; Lyons, Gretchen E; Li, Mingli; Spivey, Natali D; Norell, Håkan; Martins da Palma, Telma; Onicescu, Georgiana; Diaz-Montero, C Marcela; Garrett-Mayer, Elizabeth; Cole, David J; Le Poole, I Caroline; Nishimura, Michael I.

J Immunol; 189(4): 1627-38, 2012 Aug 15.

Artículo en Inglés | MEDLINE | ID: mdl-22798675

2.

T cells expanded in presence of IL-15 exhibit increased antioxidant capacity and innate effector molecules.

Kaur, Navtej; Naga, Osama S; Norell, Håkan; Al-Khami, Amir A; Scheffel, Matthew J; Chakraborty, Nitya G; Voelkel-Johnson, Christina; Mukherji, Bijay; Mehrotra, Shikhar.

Cytokine; 55(2): 307-17, 2011 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-21602054

3.

Primary human tumor cells expressing CD155 impair tumor targeting by down-regulating DNAM-1 on NK cells.

Carlsten, Mattias; Norell, Håkan; Bryceson, Yenan T; Poschke, Isabel; Schedvins, Kjell; Ljunggren, Hans-Gustaf; Kiessling, Rolf; Malmberg, Karl-Johan.

J Immunol; 183(8): 4921-30, 2009 Oct 15.

Artículo en Inglés | MEDLINE | ID: mdl-19801517

4.

Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas.

Kruschinski, Anna; Moosmann, Andreas; Poschke, Isabel; Norell, Håkan; Chmielewski, Markus; Seliger, Barbara; Kiessling, Rolf; Blankenstein, Thomas; Abken, Hinrich; Charo, Jehad.

Proc Natl Acad Sci U S A; 105(45): 17481-6, 2008 Nov 11.

Artículo en Inglés | MEDLINE | ID: mdl-18987320

5.

CD34-based enrichment of genetically engineered human T cells for clinical use results in dramatically enhanced tumor targeting.

Norell, Håkan; Zhang, Yi; McCracken, James; Martins da Palma, Telma; Lesher, Aaron; Liu, Yueying; Roszkowski, Jeffrey J; Temple, Anquanette; Callender, Glenda G; Clay, Timothy; Orentas, Rimas; Guevara-Patiño, José; Nishimura, Michael I.

Cancer Immunol Immunother; 59(6): 851-62, 2010 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-20052466

6.

Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial.

Norell, Håkan; Poschke, Isabel; Charo, Jehad; Wei, Wei Z; Erskine, Courtney; Piechocki, Marie P; Knutson, Keith L; Bergh, Jonas; Lidbrink, Elisabet; Kiessling, Rolf.

J Transl Med; 8: 53, 2010 Jun 07.

Artículo en Inglés | MEDLINE | ID: mdl-20529245

7.

Transduction with the antioxidant enzyme catalase protects human T cells against oxidative stress.

Ando, Takashi; Mimura, Kousaku; Johansson, C Christian; Hanson, Mikael G; Mougiakakos, Dimitrios; Larsson, Charlotte; Martins da Palma, Telma; Sakurai, Daiju; Norell, Håkan; Li, Mingli; Nishimura, Michael I; Kiessling, Rolf.

J Immunol; 181(12): 8382-90, 2008 Dec 15.

Artículo en Inglés | MEDLINE | ID: mdl-19050255

8.

HER-2/neu mediated down-regulation of MHC class I antigen processing prevents CTL-mediated tumor recognition upon DNA vaccination in HLA-A2 transgenic mice.

Vertuani, Simona; Triulzi, Chiara; Roos, Anna Karin; Charo, Jehad; Norell, Håkan; Lemonnier, François; Pisa, Pavel; Seliger, Barbara; Kiessling, Rolf.

Cancer Immunol Immunother; 58(5): 653-64, 2009 May.

Artículo en Inglés | MEDLINE | ID: mdl-18820911

9.

DNAX accessory molecule-1 mediated recognition of freshly isolated ovarian carcinoma by resting natural killer cells.

Carlsten, Mattias; Björkström, Niklas K; Norell, Håkan; Bryceson, Yenan; van Hall, Thorbald; Baumann, Bettina C; Hanson, Mikael; Schedvins, Kjell; Kiessling, Rolf; Ljunggren, Hans-Gustaf; Malmberg, Karl-Johan.

Cancer Res; 67(3): 1317-25, 2007 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-17283169

10.

Evaluating in vivo efficacy - toxicity profile of TEG001 in humanized mice xenografts against primary human AML disease and healthy hematopoietic cells.

Johanna, Inez; Straetemans, Trudy; Heijhuurs, Sabine; Aarts-Riemens, Tineke; Norell, Håkan; Bongiovanni, Laura; de Bruin, Alain; Sebestyen, Zsolt; Kuball, Jürgen.

J Immunother Cancer; 7(1): 69, 2019 03 12.

Artículo en Inglés | MEDLINE | ID: mdl-30871629

11.

Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection.

Caiado, Francisco; Maia-Silva, Diogo; Jardim, Carolina; Schmolka, Nina; Carvalho, Tânia; Reforço, Cláudia; Faria, Rita; Kolundzija, Branka; Simões, André E; Baubec, Tuncay; Vakoc, Christopher R; da Silva, Maria Gomes; Manz, Markus G; Schumacher, Ton N; Norell, Håkan; Silva-Santos, Bruno.

Nat Commun; 10(1): 4986, 2019 11 01.

Artículo en Inglés | MEDLINE | ID: mdl-31676777

12.

Author Correction: Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection.

Caiado, Francisco; Maia-Silva, Diogo; Jardim, Carolina; Schmolka, Nina; Carvalho, Tânia; Reforço, Cláudia; Faria, Rita; Kolundzija, Branka; Simões, André E; Baubec, Tuncay; Vakoc, Christopher R; da Silva, Maria Gomes; Manz, Markus G; Schumacher, Ton N; Norell, Håkan; Silva-Santos, Bruno.

Nat Commun; 10(1): 5451, 2019 Nov 26.

Artículo en Inglés | MEDLINE | ID: mdl-31772183

13.

Frequent loss of HLA-A2 expression in metastasizing ovarian carcinomas associated with genomic haplotype loss and HLA-A2-restricted HER-2/neu-specific immunity.

Norell, Håkan; Carlsten, Mattias; Ohlum, Tomas; Malmberg, Karl-Johan; Masucci, Giuseppe; Schedvins, Kjell; Altermann, Wolfgang; Handke, Diana; Atkins, Derek; Seliger, Barbara; Kiessling, Rolf.

Cancer Res; 66(12): 6387-94, 2006 Jun 15.

Artículo en Inglés | MEDLINE | ID: mdl-16778217

14.

IFN-gamma protects short-term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A-dependent mechanism.

Malmberg, Karl-Johan; Levitsky, Victor; Norell, Håkan; de Matos, Cristina Teixeira; Carlsten, Mattias; Schedvins, Kjell; Rabbani, Hodjattallah; Moretta, Alessandro; Söderström, Kalle; Levitskaya, Jelena; Kiessling, Rolf.

J Clin Invest; 110(10): 1515-23, 2002 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-12438449

15.

Intra-tumour heterogeneity - going beyond genetics.

Caiado, Francisco; Silva-Santos, Bruno; Norell, Håkan.

FEBS J; 283(12): 2245-58, 2016 06.

Artículo en Inglés | MEDLINE | ID: mdl-26945550

16.

Detection of human perforin by ELISpot and ELISA: ex vivo identification of virus-specific cells.

Zuber, Bartek; Levitsky, Victor; Jönsson, Gun; Paulie, Staffan; Samarina, Arina; Grundström, Susanna; Metkar, Sunil; Norell, Håkan; Callender, Glenda G; Froelich, Christopher; Ahlborg, Niklas.

J Immunol Methods; 302(1-2): 13-25, 2005 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-16005014

17.

Î³Î´ T cells in cancer.

Silva-Santos, Bruno; Serre, Karine; Norell, Håkan.

Nat Rev Immunol; 15(11): 683-91, 2015 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-26449179

18.

At the Bench: Preclinical rationale for exploiting NK cells and Î³Î´ T lymphocytes for the treatment of high-risk leukemias.

Norell, Håkan; Moretta, Alessandro; Silva-Santos, Bruno; Moretta, Lorenzo.

J Leukoc Biol; 94(6): 1123-39, 2013 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-24108703

19.

Inhibition of superoxide generation upon T-cell receptor engagement rescues Mart-1(27-35)-reactive T cells from activation-induced cell death.

Norell, Håkan; Martins da Palma, Telma; Lesher, Aaron; Kaur, Navtej; Mehrotra, Meenal; Naga, Osama S; Spivey, Natalie; Olafimihan, Seye; Chakraborty, Nitya G; Voelkel-Johnson, Christina; Nishimura, Michael I; Mukherji, Bijay; Mehrotra, Shikhar.

Cancer Res; 69(15): 6282-9, 2009 Aug 01.

Artículo en Inglés | MEDLINE | ID: mdl-19638595

20.

The CD16- CD56(bright) NK cell subset is resistant to reactive oxygen species produced by activated granulocytes and has higher antioxidative capacity than the CD16+ CD56(dim) subset.

Harlin, Helena; Hanson, Mikael; Johansson, C Christian; Sakurai, Daiju; Poschke, Isabel; Norell, Håkan; Malmberg, Karl-Johan; Kiessling, Rolf.

J Immunol; 179(7): 4513-9, 2007 Oct 01.

Artículo en Inglés | MEDLINE | ID: mdl-17878347

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