RESUMEN
BACKGROUND AND AIM: One of the main concerns related to peroral endoscopic myotomy (POEM) is postoperative gastroesophageal reflux (GER). The two penetrating vessels (TPVs) that are found at the boundary between the circular and oblique muscles in the posterior cardia wall have been suggested to be a good indicator of the optimal distal extent of POEM. However, the effect of performing myotomy using the TPVs as an anatomical reference on the frequency of post-POEM GER has not been studied. METHODS: This study involved consecutive patients who underwent POEM for the treatment of achalasia between April 2015 and June 2017. All enrolled patients underwent POEM in the 5 o'clock position and were divided into two groups: the conventional line group (CL group, n = 31), in which the TPVs were not exposed during submucosal tunnel dissection in the cardia, and the TPVs line group (TPVs group, n = 83), in which the TPVs were exposed and gastric myotomy was performed along the right side of the TPVs to preserve the oblique muscle. Examinations for post-POEM GER were conducted 3 months after the POEM. RESULTS: The frequency of grade B or higher reflex esophagitis was 26/83 (31.3%) in the TPVs group and 18/31 (58.1%) in the CL group (P = 0.017). Nine of 83 patients (10.8%) had GER symptoms in the TPVs group, and six of 31 (19.4%) had GER symptoms in the CL group (P = 0.23). CONCLUSIONS: The novel myotomy method preserving oblique muscle using TPVs as anatomical landmarks significantly reduced the frequency of post-POEM GER.
Asunto(s)
Puntos Anatómicos de Referencia , Acalasia del Esófago/cirugía , Reflujo Gastroesofágico/prevención & control , Complicaciones Posoperatorias/prevención & control , Piloromiotomia/métodos , Adulto , Anciano , Cardias/irrigación sanguínea , Cardias/cirugía , Esofagitis Péptica/etiología , Esofagitis Péptica/prevención & control , Esofagoscopía/métodos , Femenino , Estudios de Seguimiento , Reflujo Gastroesofágico/etiología , Humanos , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/etiología , Piloromiotomia/efectos adversos , Resultado del TratamientoRESUMEN
BACKGROUND: Although endoscopic submucosal dissection has enabled complete tumor resection and accurate pathological assessment in a manner that is less invasive than surgery, the complete resection of lesions with severe fibrosis in the submucosal layer and exhibiting the muscle-retracting sign is often difficult. We have devised a new method, peranal endoscopic myectomy (PAEM), for rectal lesions with severe fibrosis, in which dissection is performed between the inner circular and outer longitudinal muscles, and have examined the usefulness and safety of this new technique. METHODS: All of the patients who underwent PAEM in our hospital and affiliated hospitals between July 2015 and June 2017 were retrospectively reviewed. RESULTS: 10 rectal lesions were treated with PAEM. En bloc resection with a negative vertical margin was achieved in eight patients (80â%), whose lesions were mucosal (nâ=â2), shallow submucosal (nâ=â1), deep submucosal (nâ=â4), and muscle invasive (nâ=â1). The clinical course of all patients after PAEM was favorable. In patients who underwent additional surgery, anus preservation was achieved on the basis of the pathological results from PAEM. CONCLUSIONS: PAEM for lesions with severe fibrosis exhibiting the muscle-retracting sign appears to be both safe and useful.
Asunto(s)
Disección/métodos , Músculo Liso/cirugía , Neoplasias del Recto/cirugía , Recto/patología , Cirugía Endoscópica Transanal/métodos , Disección/efectos adversos , Fibrosis , Humanos , Músculo Liso/patología , Invasividad Neoplásica , Neoplasias del Recto/patología , Estudios Retrospectivos , Cirugía Endoscópica Transanal/efectos adversosRESUMEN
BACKGROUND: The feasibility and safety of endoscopic submucosal dissection (ESD) for superficial esophageal neoplasms extending to the cervical esophagus currently remain unknown because of the limited number of cases. We aimed to clarify the clinical outcomes of these cases. METHODS: This was a case series study conducted at a single institution that enrolled 26 consecutive patients with superficial esophageal neoplasms extending to the cervical esophagus who underwent ESD between July 2003 and December 2015. RESULTS: En bloc and complete resection rates were both 100â% and no major intraprocedural complications occurred. Thirteen patients were treated with prophylactic steroid therapy. The incidence of postoperative stricture in patients with a circumferential mucosal defect of more than three-quarters was 72.7â%. Four patients required entire circumferential resection, with perforation occurring after endoscopic balloon dilation (EBD) in two and EBD being required for more than 1 year in the other two. CONCLUSIONS: ESD including the cervical esophagus is technically feasible. Circumferential resection may cause refractory postoperative stricture or post-EBD perforation, so needs to be avoided where possible.
Asunto(s)
Resección Endoscópica de la Mucosa/efectos adversos , Neoplasias Esofágicas/cirugía , Perforación del Esófago/etiología , Estenosis Esofágica/etiología , Anciano , Anciano de 80 o más Años , Antiinflamatorios/uso terapéutico , Dilatación , Estenosis Esofágica/prevención & control , Estenosis Esofágica/terapia , Femenino , Humanos , Inyecciones Intralesiones , Masculino , Persona de Mediana Edad , Cuello , Resultado del Tratamiento , Triamcinolona/uso terapéuticoRESUMEN
BACKGROUND AND STUDY AIMS: Endoscopic submucosal dissection (ESD) is a reliable method that can replace surgery under certain conditions. However, limited information is available on the clinical course of T1b colorectal cancer (CRC) after ESD. The aim of the study was to clarify the feasibility of ESD for T1b CRC. PATIENTS AND METHODS: Three hundred and two patients with 312 T1 CRC were identified in this retrospective cohort study. All patients were treated with ESD, other endoscopic treatments, or surgery. In this study, we (I) investigated the en bloc resection rate of ESD and (II) compared the overall survival (OS) rate for patients who underwent ESD with additional surgery (Group A) and surgery without upfront endoscopic resection (Group B) for T1b CRC. RESULTS: No significant differences were observed in the en bloc resection rates between T1b and T1a CRC (100 vs. 98.7%), but the en bloc R0 resection rate was significantly lower in T1b CRC than in T1a CRC (64.7 vs. 97.4%). Regarding complications, perforations occurred in 2.9% of patients with T1b CRC, which was not significantly different from the rate of 5.3% in patients with T1a CRC. No significant differences were observed in the OS or recurrence-free survival (RFS) curves between Groups A and B (OS rates at 5 years: 92.3 vs. 88.9%, RFS rates at 5 years: 81.4 vs. 85.3%). Similarly, the 5-year disease-specific survival (DSS) rate of Group A was identical to that of Group B (both 100%). CONCLUSIONS: ESD for T1b CRC before surgery is a possible strategy because of the low rate of complications and favorable long-term outcomes.
Asunto(s)
Adenocarcinoma/cirugía , Neoplasias Colorrectales/cirugía , Resección Endoscópica de la Mucosa , Adenocarcinoma/mortalidad , Adenocarcinoma/patología , Adulto , Anciano , Auditoría Clínica , Neoplasias Colorrectales/mortalidad , Neoplasias Colorrectales/patología , Estudios de Factibilidad , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Invasividad Neoplásica , Estadificación de Neoplasias , Complicaciones Posoperatorias/epidemiología , Estudios Retrospectivos , Tasa de Supervivencia , Resultado del TratamientoRESUMEN
BACKGROUND AND AIM: One of the challenges during peroral endoscopic myotomy (POEM) is ensuring the appropriate length of myotomy on the gastric side. To determine the appropriate distal end of the gastric myotomy, we focused on the two penetrating vessels (TPVs) found in the gastric cardia during POEM. In the present study, we evaluated whether the TPVs could serve as an accurate indicator of the appropriate distal end of the gastric myotomy. METHODS: All patients who underwent POEM between March and August 2016 were included for this study. When making the submucosal tunnel in the 5 o'clock direction into the stomach, two vessels penetrating through the circular muscle along the edge of oblique muscle in the cardia can be exposed. We designated these two vessels as TPVs. The myotomy was extended until the second TPVs was exposed. The anal end of the submucosal tunnel was confirmed by the double-scope POEM technique, and the length from the gastroesophageal junction to the anal side end of the myotomy was measured by the scale on the endoscope. RESULTS: Among 37 patients who underwent myotomy in the 5 o'clock position, TPVs were found in 34 patients (91.2%). Sufficient submucosal tunneling on the gastric side was confirmed by the double-scope POEM technique in these 34 patients. Median length of the gastric myotomy was 3.0 cm (range 2-4 cm). CONCLUSION: TPVs appears to be a simple and reliable indicator to determine the appropriate distal end of myotomy.
Asunto(s)
Cardias/irrigación sanguínea , Cardias/cirugía , Acalasia del Esófago/cirugía , Esofagoscopía/métodos , Miotomía/métodos , Cirugía Endoscópica por Orificios Naturales/métodos , Adulto , Anciano , Estudios de Cohortes , Acalasia del Esófago/diagnóstico , Esfínter Esofágico Inferior/cirugía , Femenino , Hospitales Universitarios , Humanos , Japón , Masculino , Manometría/métodos , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Estudios Prospectivos , Medición de Riesgo , Resultado del TratamientoRESUMEN
BACKGROUND AND AIM: Currently, endoscopic submucosal dissection (ESD) is a widely accepted standard treatment for early gastric cancer, but one challenging aspect of ESD is hemostasis. We developed a new hemostatic forceps (FD-Y0007) with the aim of achieving more effective hemostasis and investigated the hemostatic ability of the FD-Y0007 during gastric ESD in humans. METHODS: This study was a prospective randomized controlled trial, which was conducted at a cancer referral center. Sixty-six patients who were scheduled to undergo ESD were enrolled and randomly assigned to either the Coagrasper or the FD-Y0007, which was used for hemostasis throughout the case. The primary end point was the time required to obtain hemostasis, which was measured for the first episode of bleeding during each case. RESULTS: Hemostasis time for the first bleeding episode during ESD was 73.0 s for the Coagrasper and 21.5 s for the FD-Y0007 (P < 0.001). When all episodes of bleeding were included, hemostasis time was 56.8 s in the Coagrasper group and 25.5 s in FD-Y0007group (P < 0.0001). The frequency of adverse events (perforation: 3.4% vs 7.1%; delayed bleeding: 0% vs 0%) was not significantly different between the two groups. CONCLUSIONS: Compared with the Coagrasper, the FD-Y0007 efficiently reduces the hemostatic time during gastric ESD with no increase in adverse events.
Asunto(s)
Endoscopía Gastrointestinal/instrumentación , Mucosa Gástrica/cirugía , Hemorragia Gastrointestinal/prevención & control , Hemostasis Endoscópica/instrumentación , Complicaciones Intraoperatorias/prevención & control , Neoplasias Gástricas/cirugía , Instrumentos Quirúrgicos , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Factores de Tiempo , Resultado del TratamientoRESUMEN
BACKGROUND AND STUDY AIMS: Improvements in the endoscopic submucosal dissection (ESD) technique have made circumferential ESD in the rectum possible. However, little is known about the clinical course after extensive ESD in the rectum. The aim of this study was to determine the stricture risk in the rectum after total or subtotal circumferential ESD. PATIENTS AND METHODS: A total of 69 patients with 69 rectal tumors that required ≥â75â% circumferential resection were identified at Kobe University Hospital and an affiliated hospital between April 2005 and May 2014. Among the patients, 61 were available for evaluation of stricture development, either by follow-up colonoscopy or by surgical specimens. The rate and possible risk factors of post-ESD strictures were investigated. RESULTS: Post-ESD rectal strictures developed in 12 patients (19.7â%). Patients who underwent total circumferential ESD developed a stricture (5/7, 71.4â%) more frequently than those with subtotal (≥â90â%) ESD (7/16, 43.8â%). Patients undergoing an ESD procedure that involved <â90â% of the circumference did not develop strictures. The strictures were membranous or <â10âmm long in all cases. Of the patients with stricture, 11 received endoscopic balloon dilation and one received bougie with short-caliber-tip transparent hood; all strictures improved following dilation therapy. Statistical analysis revealed that ≥â90â% circumferential resection was an independent risk factor for stricture, whereas morphology and size were not. CONCLUSIONS: Patients who underwent total or subtotal circumferential ESD of a rectal tumor had a high risk of stricture formation. Dilation helped to alleviate the stenosis.Study registered at University Hospital Medical Information Network (UMIN 000016559).
Asunto(s)
Adenocarcinoma/cirugía , Adenoma/cirugía , Mucosa Intestinal/cirugía , Obstrucción Intestinal/etiología , Complicaciones Posoperatorias/etiología , Neoplasias del Recto/cirugía , Recto/cirugía , Anciano , Anciano de 80 o más Años , Femenino , Estudios de Seguimiento , Humanos , Obstrucción Intestinal/diagnóstico , Obstrucción Intestinal/epidemiología , Modelos Logísticos , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/diagnóstico , Complicaciones Posoperatorias/epidemiología , Estudios Retrospectivos , Factores de Riesgo , Resultado del TratamientoRESUMEN
BACKGROUND AND STUDY AIM: Endoscopic submucosal dissection (ESD) has been applied to treat early colorectal cancers. The aim of this study was to clarify the clinical course of ESD for lesions involving the ileocecal valve (ICV) by evaluating the successful resection rates, and the risk and frequency of adverse events. PATIENTS AND METHODS: The outcome of ESD on 38 ICV lesions was compared with the outcome of 132 cecal lesions that did not involve the ICV or appendiceal orifice during the same study period. The factors related to longer procedure time, postoperative stricture development, and tumor recurrence were investigated for ESD of ICV lesions. RESULTS: There was no significant difference between the ICV and non-ICV groups in the en block resection rates. The median procedure time was significantly longer in the ICV group than in the non-ICV group, with a point estimate of the difference of 37 minutes (95â% confidence interval [CI] 20.00 to 56.00; P â<â0.01). None of the patients developed symptomatic post-ESD stricture or tumor recurrence. ESD procedure duration was ≥â120 minutes in 16 lesions andâ<â120 minutes in 22 lesions of the ICV group.âA specimen diameter ofâ≥â40âmm and tumor extension into terminal ileum were factors related to a longer procedure time (odds ratio [OR] 8.40, 95â%CI 1.53 to 46.10, Pâ=â0.01; OR 10.60, 95â%CI 2.17 to 51.40, P â<â0.01, respectively). CONCLUSIONS: ICV lesions can be resected by ESD without major adverse events or causing symptomatic stricture development. However, ESD for ICV lesions should be performed only by expert endoscopists, as the procedure requires accomplished endoscopic skill and experience.
Asunto(s)
Adenoma/cirugía , Carcinoma/cirugía , Neoplasias del Ciego/cirugía , Resección Endoscópica de la Mucosa , Neoplasias del Íleon/cirugía , Válvula Ileocecal/cirugía , Recurrencia Local de Neoplasia , Adenoma/patología , Adulto , Anciano , Anciano de 80 o más Años , Carcinoma/patología , Constricción Patológica/etiología , Resección Endoscópica de la Mucosa/efectos adversos , Estudios de Factibilidad , Femenino , Humanos , Neoplasias del Íleon/patología , Válvula Ileocecal/patología , Masculino , Persona de Mediana Edad , Invasividad Neoplásica , Tempo Operativo , Resultado del Tratamiento , Carga TumoralRESUMEN
BACKGROUND AND STUDY AIMS: Endoscopic submucosal dissection (ESD) is performed for treatment of various gastrointestinal lesions; however, the cecum in proximity to the appendiceal orifice remains a challenging area. We reviewed our experience with cecal ESD near the appendiceal orifice in order to clarify whether this procedure is a safe and effective therapeutic option. PATIENTS AND METHODS: We retrospectively reviewed ESD for lesions within approximately 12âmm of the appendiceal orifice at Kobe University Hospital and an affiliated hospital between January 2003 and December 2014.âLesions were classified as: Type 0, proximity to the appendiceal orifice but does not reach it; Type 1, reaches border of the appendix, but does not enter orifice; Type 2, enters orifice, and transition to normal appendiceal mucosa is discernible on inspection of the appendiceal lumen; and Type 3, enters orifice deeply and tumor edge cannot be observed. ESD was not performed for Type 3 lesions unless appendectomy was performed prior to ESD. RESULTS: A total of 76 lesions satisfied the inclusion criteria (47 Type 0 lesions, 20 Type 1, 6 Type 2, and 3 Type 3). En bloc resection was achieved in 72 lesions (94.7â%). Median specimen size was 49âmm (range 15â-â114âmm), and median tumor size was 35.5âmm (10â-â110âmm). One patient experienced postoperative bleeding, which was treated by endoscopic hemostasis. Another patient who experienced intraoperative perforation and was treated by clip closure later developed appendicitis; he underwent emergency ileocecal surgical resection. Another patient experienced postoperative appendicitis and recovered with antibiotic treatment. CONCLUSIONS: ESD in close proximity to the appendiceal orifice seems safe and effective.
Asunto(s)
Apéndice , Neoplasias del Ciego/patología , Neoplasias del Ciego/cirugía , Resección Endoscópica de la Mucosa/métodos , Adulto , Anciano , Anciano de 80 o más Años , Resección Endoscópica de la Mucosa/efectos adversos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Invasividad Neoplásica , Estudios Retrospectivos , Carga TumoralRESUMEN
BACKGROUND: The expanded criteria for endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) have led to an increase in the number of EGC patients who receive curative treatment involving endoscopic techniques. Identifying the factors that are associated with treatment outcomes would be helpful in the application of ESD for EGC. METHODS: Potential factors associated with incomplete ESD and with non-curative ESD were investigated using a multiple logistic regression model in EGC patients who consecutively underwent ESD according to the expanded criteria. RESULTS: A total of 363 patients with 398 EGC lesions were enrolled. The rates of complete ESD and curative ESD were 96.2 % (383/398) and 85.7 % (341/398), respectively. No significant factors associated with incomplete ESD were identified. In contrast, a tumor size >20 mm [odds ratio (OR) 3.31; 95 % confidence interval (CI) 1.74-6.29], the superficial elevated and depressed type (0-IIa + IIc or IIc + IIa) (OR 4.37; 95 % CI 1.88-9.88), and the undifferentiated type (OR 5.93; 95 % CI 1.65-19.41) were identified as independent factors associated with non-curative ESD. The superficial elevated and depressed type in particular was found to be highly related to submucosal and lymphovascular invasion. The rate of non-curative ESD in cases of this macroscopic type occurring together with a tumor size >20 mm was 58.3 %, and the adjusted OR was 16.48 (95 % CI 4.69-62.09). CONCLUSION: The results suggest that the superficial elevated and depressed type is an independent factor associated with non-curative ESD and that the risk of non-curative ESD is increased when this macroscopic type is present along with a large tumor size.
Asunto(s)
Adenocarcinoma/cirugía , Resección Endoscópica de la Mucosa/métodos , Mucosa Gástrica/cirugía , Márgenes de Escisión , Neoplasias Gástricas/cirugía , Adenocarcinoma/patología , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Mucosa Gástrica/patología , Gastroscopía/métodos , Humanos , Modelos Logísticos , Masculino , Persona de Mediana Edad , Análisis Multivariante , Estadificación de Neoplasias , Oportunidad Relativa , Estudios Retrospectivos , Factores de Riesgo , Neoplasias Gástricas/patología , Resultado del TratamientoRESUMEN
An 85-year-old man underwent endoscopic submucosal dissection for a large superficial esophageal epithelial neoplasm, which required removal of 95% of the circumference of the esophageal mucosa. Steroids were given orally to prevent esophageal stricture starting on day 3 postoperatively. In the 6th week of steroid treatment, he developed high fever without other symptoms. Chest computed tomography revealed a nodular lesion in the lung. Sputum sample showed Gram-positive, branching, filamentous bacteria, and a diagnosis of nocardiosis was suspected. Brain magnetic resonance imaging revealed multiple focal lesions which indicated dissemination of nocardiosis. Trimethoprim-sulfamethoxazole was immediately started, which led to the disappearance of pulmonary and cerebral nocardiosis with alleviation of fever. Recently, oral steroid treatment has been widely used for the prevention of esophageal stricture. However, the present case indicates the risk of life-threatening infection and the importance of close monitoring of this treatment.
Asunto(s)
Bacteriemia/inducido químicamente , Neoplasias Esofágicas/cirugía , Estenosis Esofágica/prevención & control , Esofagoscopía/métodos , Nocardiosis/inducido químicamente , Prednisolona/efectos adversos , Administración Oral , Anciano de 80 o más Años , Bacteriemia/fisiopatología , Disección/métodos , Relación Dosis-Respuesta a Droga , Esquema de Medicación , Neoplasias Esofágicas/patología , Esofagoscopía/efectos adversos , Estudios de Seguimiento , Humanos , Masculino , Membrana Mucosa/patología , Membrana Mucosa/cirugía , Nocardiosis/fisiopatología , Prednisolona/administración & dosificación , Medición de RiesgoAsunto(s)
Adenocarcinoma/cirugía , Adenoma/cirugía , Mucosa Intestinal/cirugía , Neoplasias del Recto/cirugía , Adenocarcinoma/patología , Adenoma/patología , Anciano , Disección , Endoscopía Gastrointestinal , Femenino , Humanos , Neoplasias del Recto/patología , Carga Tumoral , Cicatrización de HeridasRESUMEN
In recent years, a wide variety of health-related issues make the headlines almost everyday: the shortage of physicians, an increase in elderly patients, a difficulty in maintaining emergency pediatric care services (due to the declining birthrate), the capacity of the existing emergency medical services, medical malpractice, and the H1N1 influenza vaccine. In Japan, there has been an increasing demand for health care with an emphasis on quality over quantity based the viewpoint of health care recipients, instead of providers. Since 1995, when the obligation of informed consent was adopted, there has been an improvement, although still insufficient, in patient-oriented medical services, including attitudes towards patients. A clinical laboratory technician is required to conduct a clinical examination in a prompt and accurate manner, based on a physician's instructions written on the examination slip. Based on the results of the examination, the physician determines the diagnosis and informs the patient of it, which means that clinical laboratory technicians support the QOL of patients indirectly. Patients sometimes ask about the purpose, methods, and results of a clinical examination, prior to, following, or during its implementation. In hospitals with recently developed complex, advanced equipment for clinical examination, physicians and laboratory technicians place orders for examinations without providing any detailed explanation to patients. Patients feel very anxious and nervous wondering what clinical examination they are going to undergo, and demand an adequate explanation of the test from laboratory technicians. However, patients are often dissatisfied with their manner and remarks, such as "The attending physician will give you the results in detail", and make complaints in some cases. As a provider of health care services, clinical laboratory technicians have a responsibility to meet their patients' demands. It is very important for clinical laboratory technicians to provide patients with an explanation in a caring and considerate manner, making it simple and easy-to-understand as long as it does not contradict the laws and results of an examination.
Asunto(s)
Comunicación , Personal de Salud/psicología , Pacientes/psicología , Relaciones Profesional-Paciente , Servicios de Salud/tendencias , Humanos , Consentimiento Informado , Calidad de la Atención de SaludRESUMEN
AIM: The aim of the present research is to clarify the nursing care conducted just before and after the atomic bombing of Hiroshima in 1945. METHODS: Five surviving nurses, who were registered nursing staff at that time in Hiroshima, offered to participate in this research. Individual interviews were conducted in order to obtain the information concerning the nursing activities in the disaster-stricken areas. The collected information was collated with the documents with regard to the atomic bombing in Hiroshima, and compared with the current studies concerning nursing in disaster. FINDINGS: The five nurses who participated in the study made it clear that, from the day of the bombing, nursing care activities changed moment by moment according to the condition of the radiation victims, the stricken areas and the relief systems. Under these circumstances, the nurses tried to help the victims of the bombing by devising anything useful for nursing care. CONCLUSION: The research participants left their messages, pointing out that nurses' mental attitude to those in front of them as patients is one of the most important things to keep in mind following any major disaster.
Asunto(s)
Servicios Médicos de Urgencia/organización & administración , Acontecimientos que Cambian la Vida , Guerra Nuclear , Armas Nucleares , Atención de Enfermería/organización & administración , Traumatismos por Radiación/enfermería , Humanos , Japón , Rol de la Enfermera , Traumatismos por Radiación/etiologíaRESUMEN
BACKGROUND AND STUDY AIMS: We developed a new reporting system based on structured data entry, which selectively extracts only endoscopic findings from endoscopists' oral statements and automatically inputs them into appropriate columns in real time during endoscopic procedures. METHODS: We compared the time for endoscopic procedures and report preparation (ER time) by using an esophagogastroduodenoscopy simulator in three groups: one preparing reports using a mouse after endoscopic procedures (CE group); a second group preparing reports by using voice alone during endoscopic procedures (SR group); and the final group preparing reports by operating the system with a foot switch and inputting findings using voice during endoscopic procedures (SRâ+âFS group). For the SR and SRâ+âFS groups, we identified the recognition rates of the speech recognition system. RESULTS: Mean ER times for cases with three findings each were 162, 130 and 119 seconds in the CE, SR and SRâ+âFS groups, respectively. The mean ER times for cases with six findings each were 220, 144 and 128 seconds, respectively. The times in the SR and SRâ+âFS groups were significantly shorter than that in the CE group ( P â<â0.017). The recognition rate of the SR group for cases with three findings each was 98.4â%, and 97.6â% in the same group for cases with six findings each. The rates in the SRâ+âFS group were 95.2â% and 98.4â%, respectively. CONCLUSION: Our reporting system was demonstrated to allow an endoscopist to efficiently complete the report in real time during endoscopic procedures.
RESUMEN
A 73-year-old female with a 6-month history of progressive dysphagia and chest pain was referred to our hospital. She underwent esophagogastroduodenoscopy, which revealed abnormally strong contractions in the distal esophagus. Esophageal biopsy specimens showed massive eosinophil infiltration into the epithelium, and high-resolution manometry (HRM) also demonstrated abnormally strong contractions in the distal esophagus. Based on these results, she was diagnosed with Jackhammer esophagus (JHE) due to eosinophilic esophagitis (EoE). Treatment was started with 5 mg/day of prednisolone (PSL), and the number of peripheral blood eosinophils quickly decreased without any improvement in the patient's dysphagia. Esophageal biopsy specimens obtained after the PSL treatment showed the disappearance of eosinophils from the epithelium. However, abnormally strong contractions were still detected on HRM. Per-oral endoscopic myotomy (POEM) was performed to treat the JHE. Interestingly, the intraoperative esophageal muscle biopsy sample demonstrated massive eosinophil infiltration into the muscle layer. After the POEM, the patient's symptoms improved, and abnormal contractions were no longer detected on HRM. The current case suggests that when EoE combined with an esophageal motility disorder are refractory to steroid therapy, clinicians should be aware that motility disorders can develop due to eosinophil infiltration deep into the esophageal muscularis propria.
Asunto(s)
Esofagitis Eosinofílica/complicaciones , Trastornos de la Motilidad Esofágica/etiología , Trastornos de la Motilidad Esofágica/cirugía , Miotomía/métodos , Anciano , Biopsia , Dolor en el Pecho/etiología , Trastornos de Deglución/etiología , Endoscopía del Sistema Digestivo , Endosonografía , Esofagitis Eosinofílica/diagnóstico , Trastornos de la Motilidad Esofágica/diagnóstico , Femenino , Humanos , ManometríaRESUMEN
BACKGROUND AND STUDY AIMS: In order to perform peroral endoscopic myotomy (POEM) safely, retained liquid and food debris must be removed before the procedure is started. We developed a novel technique using a super-slim gastroscope, and a gastric tube to remove retained food debris in achalasia patients. In this study, the safety and efficacy of this novel technique were investigated. PATIENTS AND METHODS: Eleven patients with achalasia were enrolled in this study and underwent this novel method for esophageal clearance. RESULTS: All patients had complete clearance of the retained food debris using this method. The median procedure time (range) was 13 (6â-â30) minutes. There were no serious adverse events (AEs) and one minor AE of mucosal erythema due to mucosal suctioning. CONCLUSION: This novel method for esophageal clearance is safe and effective in achalasia patients with large amounts of retained food debris.
RESUMEN
A 66-year-old man was diagnosed with a gastric submucosal tumor. Endoscopic ultrasound (EUS) revealed an iso/hypoechoic mass in the third layer. No malignant cells were detected in a histological examination. Yearly follow-up endoscopy and EUS showed the slow growth of the tumor. Endoscopic submucosal dissection (ESD) was performed and a glistening tumor was resected. The lesion showed a multinodular plexiform growth pattern consisting of spindle cells with an abundant fibromyxoid stroma that was rich in small vessels. The tumor was diagnosed as plexiform fibromyxoma (PF) by immunohistochemistry. Although difficulties are associated with reaching a diagnosis preoperatively, chronological changes on EUS may contribute to the diagnosis of PF. ESD may also be useful in the diagnosis and treatment of PF.
RESUMEN
BACKGROUND AND STUDY AIMS: Peroral endoscopic myotomy (POEM) is an evolving new treatment strategy for achalasia. Although several kinds of electrosurgical knives have been used in performing POEM, the best device has yet to be determined. The FlushKnife BT is a waterjet-emitting short needle-knife with a small ball tip (BT) that offers the potential to perform all aspects of POEM with a single device. In this study, we evaluated the safety and efficiency of the FlushKnife BT for POEM. PATIENTS AND METHODS: A total of 54 consecutive patients with achalasia and other spastic esophageal motility disorders, such as jackhammer esophagus or distal esophageal spasm, who underwent POEM between January 2016 and August 2016, were included in this retrospective study. RESULTS: The median operation time was 73.0 minutes (range 39â-â184 minutes). All procedures were completed using only the FlushKnife BT without changing to any other electrosurgical instrument. The median number of additional submucosal injections with an injection needle was 0 (range 0â-â1). Endoscopic vessel sealing was performed a mean of 3 times (range 0â-â7). The median number of bleeding episodes requiring treatment with hemostatic forceps was 0 (range 0â-â5). There were no significant adverse events. Seven of 52 patients (13.5â%) reported symptoms of gastroesophageal reflux disease such as heartburn or acid reflux at 3 month follow-up. CONCLUSIONS: The FlushKnife BT enabled POEM to be performed with very few device exchanges, either for re-injection or to control intraoperative bleeding. In this uncontrolled case series, the ability of the FlushKnife BT to perform nearly all aspects of the POEM procedure seems to make it particularly well suited to this procedure.
RESUMEN
A female in her 70s underwent esophagogastroduodenoscopy (EGD) for screening, and a 0-IIa lesion measuring approximately 15 mm was detected in the descending portion of the duodenum. Due to the malignant potency of the lesion, endoscopic submucosal dissection (ESD) was performed. Microperforation occurred during ESD. The lesion was removed en bloc and the post-ESD ulcer bed was closed with clips. The next day, the patient had abdominal pain and computed tomography (CT) revealed a small amount of free air in the retroperitoneal space. Since there were no findings to suggest panperitonitis, conservative medical management including fasting and antibiotics was continued. Abdominal pain subsequently improved. However, EGD on the 8th day after ESD for follow-up showed shedding of the post-ESD ulcer that penetrated the retroperitoneal space. A surgical approach was not indicated because a few days may have already passed since postoperative perforation occurred and the spread of inflammation to the retroperitoneum was suspected. In an attempt to promote closure of the perforated cavity, we patched polyglycolic acid sheets and fibrin glue to the cavity wall on days 17, 18, and 20 after ESD. The formation of granulation tissue was detected in the cavity one week later. CT showed an abscess in the right retroperitoneum, for which CT-guided abscess puncture was performed. Thereafter, the cavity gradually decreased. After the initiation of oral intake on postoperative day (POD) 63, the general condition of the patient was stable and she was discharged on POD 87. Polyglycolic acid sheets with fibrin glue and CT-guided abscess puncture were useful for closing the large cavity that developed after duodenal postoperative perforation.