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1.
Novel 1,3,4-oxadiazole derivatives as highly potent microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors.
Bioorg Chem;
147: 107383, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38653151
2.
Novel Indole-Pyrazole Hybrids as Potential Tubulin-Targeting Agents; Synthesis, antiproliferative evaluation, and molecular modeling studies.
J Mol Struct;
12852023 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37234266
3.
Identification of novel antiplatelet agents by targeting Glycoprotein VI: A combined virtual screening study.
Bioorg Chem;
121: 105661, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35182883
4.
Simple heteroaryl modifications in the 4,5-diarylisoxazol-3-carboxylic acid scaffold favorably modulates the activity as dual mPGES-1/5-LO inhibitors with in vivo efficacy.
Bioorg Chem;
112: 104861, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33826984
5.
Discovery of Novel 5-Lipoxygenase-Activating Protein (FLAP) Inhibitors by Exploiting a Multistep Virtual Screening Protocol.
J Chem Inf Model;
60(3): 1737-1748, 2020 03 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32045233
6.
Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors.
Bioorg Med Chem;
22(12): 3096-104, 2014 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24816066
7.
Substituted 1,2,4-Triazoles as Novel and Selective Inhibitors of Leukotriene Biosynthesis Targeting 5-Lipoxygenase-Activating Protein.
ACS Omega;
8(34): 31293-31304, 2023 Aug 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-37663492
8.
Discovery and Optimization of Piperazine Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors.
ChemMedChem;
17(12): e202200137, 2022 06 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-35466565
9.
Quinazoline-4(3H)-one-7-carboxamide Derivatives as Human Soluble Epoxide Hydrolase Inhibitors with Developable 5-Lipoxygenase Activating Protein Inhibition.
ACS Omega;
7(41): 36354-36365, 2022 Oct 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36278102
10.
Novel potent benzimidazole-based microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthase.
Eur J Med Chem;
231: 114167, 2022 Mar 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35152061
11.
The 12th AFMC International Medicinal Chemistry Symposium (AIMECS 2019) in Istanbul, Turkey.
ChemMedChem;
15(1): 162-167, 2020 01 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31724830
12.
Ortho versus Meta Chlorophenyl-2,3-Benzodiazepine Analogues: Synthesis, Molecular Modeling, and Biological Activity as AMPAR Antagonists.
ACS Omega;
5(7): 3588-3595, 2020 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-32118174
13.
Protective effect of piceatannol and bioactive stilbene derivatives against hypoxia-induced toxicity in H9c2 cardiomyocytes and structural elucidation as 5-LOX inhibitors.
Eur J Med Chem;
180: 637-647, 2019 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31351395
14.
Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7.
Eur J Med Chem;
150: 876-899, 2018 Apr 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-29597170
15.
Structural insight into the optimization of ethyl 5-hydroxybenzo[g]indol-3-carboxylates and their bioisosteric analogues as 5-LO/m-PGES-1 dual inhibitors able to suppress inflammation.
Eur J Med Chem;
155: 946-960, 2018 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30015253
16.
The potential role of in silico approaches to identify novel bioactive molecules from natural resources.
Future Med Chem;
9(14): 1665-1686, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28841048
17.
4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP).
Eur J Med Chem;
113: 1-10, 2016 May 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-26922224
18.
Synthesis and biological evaluation of C(5)-substituted derivatives of leukotriene biosynthesis inhibitor BRP-7.
Eur J Med Chem;
122: 510-519, 2016 Oct 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-27423639
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