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1.

The Face of Chromatin Variants.

Flaus, Andrew; Owen-Hughes, Tom.

Cell; 178(6): 1284-1286, 2019 09 05.

Artículo en Inglés | MEDLINE | ID: mdl-31491382

2.

Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes.

Narlikar, Geeta J; Sundaramoorthy, Ramasubramanian; Owen-Hughes, Tom.

Cell; 154(3): 490-503, 2013 Aug 01.

Artículo en Inglés | MEDLINE | ID: mdl-23911317

3.

RNA polymerase II promotes the organization of chromatin following DNA replication.

Bandau, Susanne; Alvarez, Vanesa; Jiang, Hao; Graff, Sarah; Sundaramoorthy, Ramasubramanian; Gierlinski, Marek; Toman, Matt; Owen-Hughes, Tom; Sidoli, Simone; Lamond, Angus; Alabert, Constance.

EMBO Rep; 25(3): 1387-1414, 2024 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-38347224

4.

ATRX: Put me on repeat.

Whitehouse, Iestyn; Owen-Hughes, Tom.

Cell; 143(3): 335-6, 2010 Oct 29.

Artículo en Inglés | MEDLINE | ID: mdl-21029854

5.

BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design.

Farnaby, William; Koegl, Manfred; Roy, Michael J; Whitworth, Claire; Diers, Emelyne; Trainor, Nicole; Zollman, David; Steurer, Steffen; Karolyi-Oezguer, Jale; Riedmueller, Carina; Gmaschitz, Teresa; Wachter, Johannes; Dank, Christian; Galant, Michael; Sharps, Bernadette; Rumpel, Klaus; Traxler, Elisabeth; Gerstberger, Thomas; Schnitzer, Renate; Petermann, Oliver; Greb, Peter; Weinstabl, Harald; Bader, Gerd; Zoephel, Andreas; Weiss-Puxbaum, Alexander; Ehrenhöfer-Wölfer, Katharina; Wöhrle, Simon; Boehmelt, Guido; Rinnenthal, Joerg; Arnhof, Heribert; Wiechens, Nicola; Wu, Meng-Ying; Owen-Hughes, Tom; Ettmayer, Peter; Pearson, Mark; McConnell, Darryl B; Ciulli, Alessio.

Nat Chem Biol; 15(7): 672-680, 2019 07.

Artículo en Inglés | MEDLINE | ID: mdl-31178587

6.

Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design.

Farnaby, William; Koegl, Manfred; Roy, Michael J; Whitworth, Claire; Diers, Emelyne; Trainor, Nicole; Zollman, David; Steurer, Steffen; Karolyi-Oezguer, Jale; Riedmueller, Carina; Gmaschitz, Teresa; Wachter, Johannes; Dank, Christian; Galant, Michael; Sharps, Bernadette; Rumpel, Klaus; Traxler, Elisabeth; Gerstberger, Thomas; Schnitzer, Renate; Petermann, Oliver; Greb, Peter; Weinstabl, Harald; Bader, Gerd; Zoephel, Andreas; Weiss-Puxbaum, Alexander; Ehrenhöfer-Wölfer, Katharina; Wöhrle, Simon; Boehmelt, Guido; Rinnenthal, Joerg; Arnhof, Heribert; Wiechens, Nicola; Wu, Meng-Ying; Owen-Hughes, Tom; Ettmayer, Peter; Pearson, Mark; McConnell, Darryl B; Ciulli, Alessio.

Nat Chem Biol; 15(8): 846, 2019 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-31267096

7.

PICH: a DNA translocase specially adapted for processing anaphase bridge DNA.

Biebricher, Andreas; Hirano, Seiki; Enzlin, Jacqueline H; Wiechens, Nicola; Streicher, Werner W; Huttner, Diana; Wang, Lily H-C; Nigg, Erich A; Owen-Hughes, Tom; Liu, Ying; Peterman, Erwin; Wuite, Gijs J L; Hickson, Ian D.

Mol Cell; 51(5): 691-701, 2013 Sep 12.

Artículo en Inglés | MEDLINE | ID: mdl-23973328

8.

Identification of Elg1 interaction partners and effects on post-replication chromatin re-formation.

Gali, Vamsi K; Dickerson, David; Katou, Yuki; Fujiki, Katsunori; Shirahige, Katsuhiko; Owen-Hughes, Tom; Kubota, Takashi; Donaldson, Anne D.

PLoS Genet; 14(11): e1007783, 2018 11.

Artículo en Inglés | MEDLINE | ID: mdl-30418970

9.

DNA repair factor APLF is a histone chaperone.

Mehrotra, Pawan Vinod; Ahel, Dragana; Ryan, Daniel P; Weston, Ria; Wiechens, Nicola; Kraehenbuehl, Rolf; Owen-Hughes, Tom; Ahel, Ivan.

Mol Cell; 41(1): 46-55, 2011 Jan 07.

Artículo en Inglés | MEDLINE | ID: mdl-21211722

10.

The histone chaperones Nap1 and Vps75 bind histones H3 and H4 in a tetrameric conformation.

Bowman, Andrew; Ward, Richard; Wiechens, Nicola; Singh, Vijender; El-Mkami, Hassane; Norman, David George; Owen-Hughes, Tom.

Mol Cell; 41(4): 398-408, 2011 Feb 18.

Artículo en Inglés | MEDLINE | ID: mdl-21329878

11.

The Chromatin Remodelling Enzymes SNF2H and SNF2L Position Nucleosomes adjacent to CTCF and Other Transcription Factors.

Wiechens, Nicola; Singh, Vijender; Gkikopoulos, Triantaffyllos; Schofield, Pieta; Rocha, Sonia; Owen-Hughes, Tom.

PLoS Genet; 12(3): e1005940, 2016 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-27019336

12.

How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?

Schurch, Nicholas J; Schofield, Pietá; Gierlinski, Marek; Cole, Christian; Sherstnev, Alexander; Singh, Vijender; Wrobel, Nicola; Gharbi, Karim; Simpson, Gordon G; Owen-Hughes, Tom; Blaxter, Mark; Barton, Geoffrey J.

RNA; 22(6): 839-51, 2016 06.

Artículo en Inglés | MEDLINE | ID: mdl-27022035

13.

Establishment of a promoter-based chromatin architecture on recently replicated DNA can accommodate variable inter-nucleosome spacing.

Fennessy, Ross T; Owen-Hughes, Tom.

Nucleic Acids Res; 44(15): 7189-203, 2016 09 06.

Artículo en Inglés | MEDLINE | ID: mdl-27106059

14.

The histone chaperone Vps75 forms multiple oligomeric assemblies capable of mediating exchange between histone H3-H4 tetramers and Asf1-H3-H4 complexes.

Hammond, Colin M; Sundaramoorthy, Ramasubramanian; Larance, Mark; Lamond, Angus; Stevens, Michael A; El-Mkami, Hassane; Norman, David G; Owen-Hughes, Tom.

Nucleic Acids Res; 44(13): 6157-72, 2016 07 27.

Artículo en Inglés | MEDLINE | ID: mdl-27036862

15.

A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation.

Neumann, Heinz; Hancock, Susan M; Buning, Ruth; Routh, Andrew; Chapman, Lynda; Somers, Joanna; Owen-Hughes, Tom; van Noort, John; Rhodes, Daniela; Chin, Jason W.

Mol Cell; 36(1): 153-63, 2009 Oct 09.

Artículo en Inglés | MEDLINE | ID: mdl-19818718

16.

High resolution imaging reveals heterogeneity in chromatin states between cells that is not inherited through cell division.

Dickerson, David; Gierlinski, Marek; Singh, Vijender; Kitamura, Etsushi; Ball, Graeme; Tanaka, Tomoyuki U; Owen-Hughes, Tom.

BMC Cell Biol; 17(1): 33, 2016 09 08.

Artículo en Inglés | MEDLINE | ID: mdl-27609610

17.

Statistical models for RNA-seq data derived from a two-condition 48-replicate experiment.

Gierlinski, Marek; Cole, Christian; Schofield, Pietà; Schurch, Nicholas J; Sherstnev, Alexander; Singh, Vijender; Wrobel, Nicola; Gharbi, Karim; Simpson, Gordon; Owen-Hughes, Tom; Blaxter, Mark; Barton, Geoffrey J.

Bioinformatics; 31(22): 3625-30, 2015 Nov 15.

Artículo en Inglés | MEDLINE | ID: mdl-26206307

18.

The histone chaperones Vps75 and Nap1 form ring-like, tetrameric structures in solution.

Bowman, Andrew; Hammond, Colin M; Stirling, Andrew; Ward, Richard; Shang, Weifeng; El-Mkami, Hassane; Robinson, David A; Svergun, Dmitri I; Norman, David G; Owen-Hughes, Tom.

Nucleic Acids Res; 42(9): 6038-51, 2014 May.

Artículo en Inglés | MEDLINE | ID: mdl-24688059

19.

The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains.

Ryan, Daniel P; Sundaramoorthy, Ramasubramanian; Martin, David; Singh, Vijender; Owen-Hughes, Tom.

EMBO J; 30(13): 2596-609, 2011 May 27.

Artículo en Inglés | MEDLINE | ID: mdl-21623345

20.

The SWI/SNF complex acts to constrain distribution of the centromeric histone variant Cse4.

Gkikopoulos, Triantaffyllos; Singh, Vijender; Tsui, Kyle; Awad, Salma; Renshaw, Matthew J; Scholfield, Pieta; Barton, Geoffrey J; Nislow, Corey; Tanaka, Tomoyuki U; Owen-Hughes, Tom.

EMBO J; 30(10): 1919-27, 2011 May 18.

Artículo en Inglés | MEDLINE | ID: mdl-21505420

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