1.
J Org Chem
; 73(13): 5198-201, 2008 Jul 04.
Artículo
en Inglés
| MEDLINE
| ID: mdl-18529082
RESUMEN
An enantioselective unified strategy for the syntheses of the oxylipin class of natural products was accomplished. Our strategy relies on three catalytic steps: (a) organocatalytic cyclopropanation, (b) the catalytic asymmetric transfer hydrogenation (CATHy) reaction, and (c) the Nozaki-Hiyama-Kishi reaction.
2.
J Org Chem
; 71(1): 337-40, 2006 Jan 06.
Artículo
en Inglés
| MEDLINE
| ID: mdl-16388653
RESUMEN
[reaction: see text] An efficient protocol has been developed using D-(2R)-Oppolzer sultam as a chiral auxiliary for generating anti/syn diastereomers with high enantiopurity and utilized in the efficient synthesis of natural product belactosin C and their synthetic congeners. It has been observed that a variation in the stoichiometry of the Lewis acid led to a difference in anti/syn selectivity.