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1.
Cellular Effects of Selected Unsymmetrical Bisacridines on the Multicellular Tumor Spheroids of HCT116 Colon and A549 Lung Cancer Cells in Comparison to Monolayer Cultures.
Int J Mol Sci;
24(21)2023 Oct 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-37958764
2.
In Vitro Enzyme Kinetics and NMR-Based Product Elucidation for Glutathione S-Conjugation of the Anticancer Unsymmetrical Bisacridine C-2028 in Liver Microsomes and Cytosol: Major Role of Glutathione S-Transferase M1-1 Isoenzyme.
Molecules;
28(19)2023 Sep 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-37836655
3.
Foliate-Targeting Quantum Dots-ß-Cyclodextrin Nanocarrier for Efficient Delivery of Unsymmetrical Bisacridines to Lung and Prostate Cancer Cells.
Int J Mol Sci;
23(3)2022 Jan 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-35163186
4.
A new 1-nitro-9-aminoacridine derivative targeting yeast topoisomerase II able to overcome fluconazole-resistance.
Bioorg Med Chem Lett;
35: 127815, 2021 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33486051
5.
The Effect of Conjugation with Octaarginine, a Cell-Penetrating Peptide on Antifungal Activity of Imidazoacridinone Derivative.
Int J Mol Sci;
22(24)2021 Dec 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34947987
6.
In vitro biological evaluation of a novel folic acid-targeted receptor quantum dot-ß-cyclodextrin carrier for C-2028 unsymmetrical bisacridine in the treatment of human lung and prostate cancers.
Pharmacol Rep;
2024 Jun 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-38888724
7.
Targeting yeast topoisomerase II by imidazo and triazoloacridinone derivatives resulting in their antifungal activity.
Sci Rep;
14(1): 3594, 2024 02 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-38351313
8.
Electrochemistry/mass spectrometry (EC/MS) for fast generation and identification of novel reactive metabolites of two unsymmetrical bisacridines with anticancer activity.
J Pharm Biomed Anal;
235: 115607, 2023 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-37523868
9.
The interactions of monomeric acridines and unsymmetrical bisacridines (UAs) with DNA duplexes: an insight provided by NMR and MD studies.
Sci Rep;
13(1): 3431, 2023 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36859494
10.
pH-Responsive Drug Delivery Nanoplatforms as Smart Carriers of Unsymmetrical Bisacridines for Targeted Cancer Therapy.
Pharmaceutics;
15(1)2023 Jan 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36678830
11.
Electrochemical simulation of metabolic reduction and conjugation reactions of unsymmetrical bisacridine antitumor agents, C-2028 and C-2053.
J Pharm Biomed Anal;
197: 113970, 2021 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33618132
12.
Photoresponsive Amide-Based Derivatives of Azobenzene-4,4'-Dicarboxylic Acid-Experimental and Theoretical Studies.
Materials (Basel);
14(14)2021 Jul 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-34300906
13.
Antifungal Activity of Capridine ß as a Consequence of Its Biotransformation into Metabolite Affecting Yeast Topoisomerase II Activity.
Pathogens;
10(2)2021 Feb 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33572407
14.
Design, synthesis and high antitumor potential of new unsymmetrical bisacridine derivatives towards human solid tumors, specifically pancreatic cancers and their unique ability to stabilize DNA G-quadruplexes.
Eur J Med Chem;
204: 112599, 2020 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32736230
15.
The overexpression of CPR and P450 3A4 in pancreatic cancer cells changes the metabolic profile and increases the cytotoxicity and pro-apoptotic activity of acridine antitumor agent, C-1748.
Biochem Pharmacol;
142: 21-38, 2017 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28645477
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