Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 5 de 5
Filtrar
Más filtros

Bases de datos
País/Región como asunto
Tipo del documento
Asunto de la revista
País de afiliación
Intervalo de año de publicación
1.
Am J Hum Genet ; 101(3): 353-368, 2017 Sep 07.
Artículo en Inglés | MEDLINE | ID: mdl-28844488

RESUMEN

Zoroastrianism is one of the oldest extant religions in the world, originating in Persia (present-day Iran) during the second millennium BCE. Historical records indicate that migrants from Persia brought Zoroastrianism to India, but there is debate over the timing of these migrations. Here we present genome-wide autosomal, Y chromosome, and mitochondrial DNA data from Iranian and Indian Zoroastrians and neighboring modern-day Indian and Iranian populations and conduct a comprehensive genome-wide genetic analysis in these groups. Using powerful haplotype-based techniques, we find that Zoroastrians in Iran and India have increased genetic homogeneity relative to other sampled groups in their respective countries, consistent with their current practices of endogamy. Despite this, we infer that Indian Zoroastrians (Parsis) intermixed with local groups sometime after their arrival in India, dating this mixture to 690-1390 CE and providing strong evidence that Iranian Zoroastrian ancestry was maintained primarily through the male line. By making use of the rich information in DNA from ancient human remains, we also highlight admixture in the ancestors of Iranian Zoroastrians dated to 570 BCE-746 CE, older than admixture seen in any other sampled Iranian group, consistent with a long-standing isolation of Zoroastrians from outside groups. Finally, we report results, and challenges, from a genome-wide scan to identify genomic regions showing signatures of positive selection in present-day Zoroastrians that might correlate to the prevalence of particular diseases among these communities.


Asunto(s)
Cromosomas Humanos Y/genética , ADN Mitocondrial/genética , Etnicidad/genética , Flujo Génico , Variación Genética , Genética de Población , Selección Genética , Herencia , Humanos , India/epidemiología , Irán/epidemiología , Desequilibrio de Ligamiento , Masculino , Religión
2.
Nature ; 466(7303): 238-42, 2010 Jul 08.
Artículo en Inglés | MEDLINE | ID: mdl-20531471

RESUMEN

Contemporary Jews comprise an aggregate of ethno-religious communities whose worldwide members identify with each other through various shared religious, historical and cultural traditions. Historical evidence suggests common origins in the Middle East, followed by migrations leading to the establishment of communities of Jews in Europe, Africa and Asia, in what is termed the Jewish Diaspora. This complex demographic history imposes special challenges in attempting to address the genetic structure of the Jewish people. Although many genetic studies have shed light on Jewish origins and on diseases prevalent among Jewish communities, including studies focusing on uniparentally and biparentally inherited markers, genome-wide patterns of variation across the vast geographic span of Jewish Diaspora communities and their respective neighbours have yet to be addressed. Here we use high-density bead arrays to genotype individuals from 14 Jewish Diaspora communities and compare these patterns of genome-wide diversity with those from 69 Old World non-Jewish populations, of which 25 have not previously been reported. These samples were carefully chosen to provide comprehensive comparisons between Jewish and non-Jewish populations in the Diaspora, as well as with non-Jewish populations from the Middle East and north Africa. Principal component and structure-like analyses identify previously unrecognized genetic substructure within the Middle East. Most Jewish samples form a remarkably tight subcluster that overlies Druze and Cypriot samples but not samples from other Levantine populations or paired Diaspora host populations. In contrast, Ethiopian Jews (Beta Israel) and Indian Jews (Bene Israel and Cochini) cluster with neighbouring autochthonous populations in Ethiopia and western India, respectively, despite a clear paternal link between the Bene Israel and the Levant. These results cast light on the variegated genetic architecture of the Middle East, and trace the origins of most Jewish Diaspora communities to the Levant.


Asunto(s)
Genoma Humano/genética , Judíos/genética , África del Norte/etnología , Alelos , Asia , Cromosomas Humanos Y/genética , ADN Mitocondrial/genética , Etiopía/etnología , Europa (Continente) , Genotipo , Geografía , Humanos , India/etnología , Judíos/clasificación , Medio Oriente/etnología , Filogenia , Análisis de Componente Principal
3.
Cult Med Psychiatry ; 29(2): 193-224, 2005 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-16249950

RESUMEN

The paper examines the impact of genetic research on the religious identity of the Bene Israel Indian Jewish community and the Lemba Judaising group of southern Africa. It demonstrates how DNA tests which happened to support the possibility of the communities' legends of origin affected their self-perception, the way they are viewed by their neighbors, and their image in the West. It is argued that in both cases what accounted most for the Bene Israel and Lemba responses to the tests was the way the results were portrayed in the mass media, the history of the development of Judaism in their communities, and the local realities.


Asunto(s)
Genética de Población , Judíos/genética , Judaísmo/historia , Identificación Social , África Austral , ADN/análisis , Etiopía , Haplotipos/genética , Historia Antigua , Humanos , India
4.
Dev World Bioeth ; 3(2): 112-8, 2003 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-14768642

RESUMEN

This commentary examines the use of Y-chromosome testing to reconstruct a genetic ancestry for the Lemba, a group in southern Africa that has long considered itself Jewish. The commentary looks especially at the reasons why this project drew such attention from the mainstream media.


Asunto(s)
Población Negra/genética , Investigación Genética , Pruebas Genéticas , Genética de Población , Judíos/genética , Linaje , Cara , Genética de Población/métodos , Historia del Siglo XIX , Humanos , Judaísmo , Masculino , Medios de Comunicación de Masas , Medio Oriente/etnología , Cambio Social , Identificación Social , Sudáfrica , Zimbabwe
5.
Dev World Bioeth ; 3(2): 178-85, 2003 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-14768650

RESUMEN

The Bene Israel is a Jewish community in western India whose origins are unknown from conventional sources. This paper discusses a genetic ancestry study that mapped Bene Israel genealogies and the impact of the study on the Bene Israel.


Asunto(s)
Investigación Genética , Pruebas Genéticas , Judíos/genética , Linaje , Grupos de Población/genética , Pruebas Genéticas/psicología , Haplotipos/genética , Humanos , India , Cambio Social , Clase Social , Identificación Social , Encuestas y Cuestionarios
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA