Evaluation of maxillary alveolar ridge formation and ridge continuity after secondary alveolar bone grafting using cancellous and cortico-cancellous bone graft in unilateral cleft alveolus using cone beam computed tomographic scan - a randomized controlled trial.

PURPOSE: The aim of present study was to compare and evaluate the maxillary alveolar ridge formation and ridge continuity using cancellous and corticocanellous bone graft harvested from anterior iliac crest for complete secondary unilateral cleft alveolus defects. MATERIAL AND METHOD: All patients were randomized into two groups for secondary alveolar bone grafting. Group I (n = 10) patients treated with cancellous particulate bone graft and group II (n = 10) patients treated with cortico-cancellous block graft. Maxillary alveolar ridge bone formation was assessed with the help of cone beam computed tomography (CBCT) scan using Planmeca Romexis Viewer 5.0 software. Maxillary alveolar ridge continuity was assessed with axial section of CBCT scan and clinical occlusal photograph. Preoperative CBCT scan and occlusal photographs were compared with post-op 6-month CBCT scan and occlusal photographs. RESULT: The mean preoperative volume of cleft defect in group I was 4.2576 cm3 whereas in group II it was 4.2268 cm3. The mean postoperative bone bridge formation after 6 months in group I was 4.055 cm3 whereas in group II it was 3.8103 cm3. Preoperative and 6-month postoperative axial sections of CBCT scans were compared and 100% maxillary alveolar ridge continuity was achieved in both groups. The preoperative and postoperative occlusal photographs of both the groups were compared and showed accurate bone and well aligned maxillary alveolar ridge formation in all patients. CONCLUSION: The present study concluded that maxillary alveolar ridge formation rate is less in cortico-cancellous iliac crest block graft compared to cancellous iliac crest particulate graft, but is equally good as cancellous bone graft. CLINICAL TRIAL REGISTRATION NO: (REF/2020/09/031605)/ CTRI/ 2020/09/028001.

A Comparative Volumetric Assessment of Cancellous and Cortico-Cancellous Bone Graft in the Management of Unilateral Alveolar Cleft Defect using Cone Beam Computed Tomographic Scan-A Randomized Controlled Trial.

Introduction: The most commonly preferred procedure for surgical correction of alveolar bone defect and restoration of bony contour is anterior iliac crest graft. Since the ancient time, cancellous bone graft is considered as a gold standard, but it has a high resorption rate and many other disadvantages, and hence we conducted this study to evaluate the efficacy of Cortico-cancellous bone graft harvested from anterior iliac crest to find out whether it can be used as a substitute for cancellous bone graft or not. Aims & Objectives: The objectives of present study were to compare and evaluate the bone bridge formation rate, resorption rate, and uptake of bone graft at recipient site using cancellous and corticocanellous bone graft harvested from anterior iliac crest for complete unilateral cleft alveolus defects. Patients and Method: Total 20 patients were divided into two groups by lottery method of randomization. Each group comprises of total 10 patients treated with cancellous bone graft in group 1 and corticocancellous bone graft in group 2 patients harvested from anterior iliac crest. Preoperatively and postoperatively CBCT scans were taken for each patient to calculate the volume of cleft defect and volume of newly formed bone after 6 months, respectively. Grafting fill rate was calculated and mean graft filling rate observed in the patients of group 1 was 1.14 ± 0.03, and in patients of group 2, it was 1.17 ± 0.03. The mean bone bridge formation rate observed in the patients of group 1 was 91.85 ± 0.81 and in patients of group 2 it was 87.89 ± 0.75. The mean bone resorption rate obtained in the patients of group 1 was 18.74 ± 0.42 and in patients of group 2 it was 16.87 ± 0.52. Conclusion: The present study concluded that accurate estimation of the amount required for bone grafting in the alveolar cleft can be performed by CBCT scan data using Planmeca Romexis viewer version 5.0 software. Even though the corticocancellous bone graft has some drawbacks, it is equally good as cancellous bone graft because of its less resorption than cancellous bone graft and can be considered as a second best option for secondary alveolar bone grafting.Clinical trial registration no (REF/2020/09/031605)/(CTRI/2020/09/028001).

Qualitative assesement of newly formed bone after distraction osteogenesis of mandible in patients with facial asymmetry using 3 dimensional computed tomography.

INTRODUCTION: Distraction osteogenesis is a surgical technique of new bone formation between the osteotomized bone segments with the help of gradual incremental traction. As distraction osteogenesis is slow biologic process, soft tissue changes gradually follow the new bone formation. Mandibular distraction is one of the accepted modalities to treat the triad of TMJ ankylosis, obstructive sleep apnoea & micrognathia and also for facial asymmetry cases like hemifacial microsomia, mandibular hypoplasia etc. After the distraction osteogenesis, some relapse has been noticed in patients. Therefore, this study was conducted to assess the quality of the newly formed bone after distraction osteogenesis of mandible using 3 dimensional computed tomography (3DCT Scan) to evaluate its relation with relapse if any. OBJECTIVES: 1) To objectively analyse the quality of bone formed after mandibular distraction osteogenesis.2) To observe the site & architecture of newly formed bone after distraction is complete. MATERIAL AND METHODS: Total 5 patients of facial asymmetry reported to the Department of Oral and Maxillofacial Surgery were enrolled. Distraction osteogenesis of mandible was carried out in all the patients. Radiographic analysis (CT Scan) was done after 1 year of surgery for further planning and management of deformity. The non-distracted site was considered as a control side and it was compared with newly formed bone at distraction site. The standard & universally accepted radio density measuring Hounsfield Unit (HU) in 3DCT scan was calculated in axial,coronal, sagittal sections from distraction site and it was compared with non-distraction site, as Hounsfield unit is considered as a standard tool for measuring the bone density to evaluate the quality as well as quantity of newly formed bone. RESULTS: The total mean Hounsfield Unit of distracted site of all three sections was 359.8 HU and non-distracted site was 545.2 HU. Statistical analysis was carried out using students paired ttest and p value was obtained which was <0.01 suggestive of statistically significant difference between the quality of bone in distracted site and non-distracted site. CONCLUSION: The findings of our study concluded that the quality of bone formed after distraction osteogenesis was satisfactory but it was less mineralized with less dense trabecular pattern compared to non-distracted bone region of mandible which leads to some relapse. Therefore it was advisable to reinforce the distracted bone segment by cutting the activation arm of distractor itself or mini plate or reconstruction plate to prevent relapse.