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1.
Anti-C1s humanized monoclonal antibody SAR445088: A classical pathway complement inhibitor specific for the active form of C1s.
Clin Immunol;
251: 109629, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37149117
2.
Inhibition of complement C1s improves severe hemolytic anemia in cold agglutinin disease: a first-in-human trial.
Blood;
133(9): 893-901, 2019 02 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-30559259
3.
C1s Inhibition by BIVV009 (Sutimlimab) Prevents Complement-Enhanced Activation of Autoimmune Human B Cells In Vitro.
J Immunol;
202(4): 1200-1209, 2019 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30635392
4.
Uncoupling complement C1s activation from C1q binding in apoptotic cell phagocytosis and immunosuppressive capacity.
Clin Immunol;
163: 84-90, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26769276
5.
TNT003, an inhibitor of the serine protease C1s, prevents complement activation induced by cold agglutinins.
Blood;
123(26): 4015-22, 2014 Jun 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-24695853
6.
Pharmacology of the novel antiangiogenic peptide ATN-161 (Ac-PHSCN-NH2): observation of a U-shaped dose-response curve in several preclinical models of angiogenesis and tumor growth.
Clin Cancer Res;
14(7): 2137-44, 2008 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18381955
7.
Effect of a C1s Inhibitor on the Efficacy of Anti-Capsular Antibodies against Neisseria meningitidis and Streptococcus pneumoniae.
Immunohorizons;
3(11): 519-530, 2019 11 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31690560
8.
Specific Inhibition of the Classical Complement Pathway Prevents C3 Deposition along the Dermal-Epidermal Junction in Bullous Pemphigoid.
J Invest Dermatol;
139(12): 2417-2424.e2, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31229501
9.
Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-Met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice.
Cancer Res;
65(17): 7775-81, 2005 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16140945
10.
A non-RGD-based integrin binding peptide (ATN-161) blocks breast cancer growth and metastasis in vivo.
Mol Cancer Ther;
5(9): 2271-80, 2006 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-16985061
11.
Complement-Mediated Enhancement of Monocyte Adhesion to Endothelial Cells by HLA Antibodies, and Blockade by a Specific Inhibitor of the Classical Complement Cascade, TNT003.
Transplantation;
101(7): 1559-1572, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28640789
12.
Blockade of HLA Antibody-Triggered Classical Complement Activation in Sera From Subjects Dosed With the Anti-C1s Monoclonal Antibody TNT009-Results from a Randomized First-in-Human Phase 1 Trial.
Transplantation;
101(10): 2410-2418, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28926521
13.
Histidine-proline-rich glycoprotein has potent antiangiogenic activity mediated through the histidine-proline-rich domain.
Cancer Res;
62(18): 5344-50, 2002 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12235005
14.
Inhibition of tumor cell migration by LD22-4, an N-terminal fragment of 24-kDa FGF2, is mediated by Neuropilin 1.
Cancer Res;
73(11): 3316-25, 2013 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23667176
15.
Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes.
Nat Struct Mol Biol;
15(4): 422-3, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-18376415
16.
Structure of human urokinase plasminogen activator in complex with its receptor.
Science;
311(5761): 656-9, 2006 Feb 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-16456079
17.
Insulinlike growth factor-I-mediated migration and invasion of human colon carcinoma cells requires activation of c-Met and urokinase plasminogen activator receptor.
Ann Surg;
241(5): 748-56; discussion 756-8, 2005 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15849510
18.
Inhibition of cell migration and angiogenesis by the amino-terminal fragment of 24kD basic fibroblast growth factor.
J Biol Chem;
277(34): 31056-61, 2002 Aug 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-12063256
19.
Critical role of integrin alpha 5 beta 1 in urokinase (uPA)/urokinase receptor (uPAR, CD87) signaling.
J Biol Chem;
278(32): 29863-72, 2003 Aug 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-12754207
20.
Inhibition of integrin alpha5beta1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice.
Int J Cancer;
104(4): 496-503, 2003 Apr 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-12584749
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