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1.
Potentiating the radiation-induced type I interferon antitumoral immune response by ATM inhibition in pancreatic cancer.
JCI Insight;
9(6)2024 Feb 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-38376927
2.
DNA-PK Inhibition and Radiation Promote Antitumoral Immunity through RNA Polymerase III in Pancreatic Cancer.
Mol Cancer Res;
20(7): 1137-1150, 2022 07 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-35348737
3.
Translation of DNA Damage Response Inhibitors as Chemoradiation Sensitizers From the Laboratory to the Clinic.
Int J Radiat Oncol Biol Phys;
111(5): e38-e53, 2021 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34348175
4.
Cytidine Deaminase APOBEC3A Regulates PD-L1 Expression in Cancer Cells in a JNK/c-JUN-Dependent Manner.
Mol Cancer Res;
19(9): 1571-1582, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34045311
5.
Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells.
Mol Cancer Ther;
8(1): 45-54, 2009 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19139112
6.
Dose Escalation Trial of the Wee1 Inhibitor Adavosertib (AZD1775) in Combination With Gemcitabine and Radiation for Patients With Locally Advanced Pancreatic Cancer.
J Clin Oncol;
37(29): 2643-2650, 2019 10 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31398082
7.
Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy.
Cancer Res;
79(15): 3940-3951, 2019 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31101760
8.
The contribution of DNA replication stress marked by high-intensity, pan-nuclear γH2AX staining to chemosensitization by CHK1 and WEE1 inhibitors.
Cell Cycle;
17(9): 1076-1086, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29895190
9.
PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors.
Mol Cancer Res;
16(2): 222-232, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29133592
10.
Role of checkpoint kinase 1 in preventing premature mitosis in response to gemcitabine.
Cancer Res;
65(15): 6835-42, 2005 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16061666
11.
Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis.
Cancer Res;
77(4): 960-970, 2017 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27923831
12.
Dissociation of gemcitabine chemosensitization by CHK1 inhibition from cell cycle checkpoint abrogation and aberrant mitotic entry.
Cell Cycle;
15(5): 730-9, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26890478
13.
Fbxw7 Deletion Accelerates KrasG12D-Driven Pancreatic Tumorigenesis via Yap Accumulation.
Neoplasia;
18(11): 666-673, 2016 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-27764699
14.
Sensitization of Pancreatic Cancers to Gemcitabine Chemoradiation by WEE1 Kinase Inhibition Depends on Homologous Recombination Repair.
Neoplasia;
17(10): 757-66, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26585231
15.
Inhibition of protein phosphatase 2A radiosensitizes pancreatic cancers by modulating CDC25C/CDK1 and homologous recombination repair.
Clin Cancer Res;
19(16): 4422-32, 2013 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23780887
16.
Sensitization of pancreatic cancer to chemoradiation by the Chk1 inhibitor MK8776.
Clin Cancer Res;
19(16): 4412-21, 2013 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23804422
17.
Sensitization of pancreatic cancer stem cells to gemcitabine by Chk1 inhibition.
Neoplasia;
14(6): 519-25, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22787433
18.
Selective radiosensitization of p53 mutant pancreatic cancer cells by combined inhibition of Chk1 and PARP1.
Cell Cycle;
10(24): 4321-9, 2011 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22134241
19.
Assessment of chk1 phosphorylation as a pharmacodynamic biomarker of chk1 inhibition.
Clin Cancer Res;
17(11): 3706-15, 2011 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21482692
20.
Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair.
Cancer Res;
70(12): 4972-81, 2010 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20501833