RESUMEN
Technetium-99m DPD and Tc-99m(Sn)MDP were compared regarding the quality of skeletal images and the compartmental kinetic data, in two groups of nine normal subjects. No difference in scan quality was found. Data derived from compartmental kinetic analysis suggest that MDP has a higher bone uptake and a lower soft-tissue retention in comparison with DPD.
Asunto(s)
Huesos/diagnóstico por imagen , Difosfonatos/metabolismo , Compuestos de Organotecnecio , Medronato de Tecnecio Tc 99m , Tecnecio/metabolismo , Adulto , Anciano , Computadores , Humanos , Cinética , Tasa de Depuración Metabólica , Persona de Mediana Edad , Modelos Biológicos , CintigrafíaRESUMEN
An haematological study and haemoglobin biosynthesis in vitro carried out on the members of family from Ostuni (Apulia), three of which present Hb H in quantities varying from 26 to 28 and 29%, has been reported. On the basis of the haematological and biosynthetical data, the Authors think that the genetics of the alpha-thalassemia in the family under observation is similar to that observed in South East Asia according to the hypothesis of the existence of two alpha loci. The biosynthetical data fall into the values obtained by Kan and Coll. even if with slight differences.
Asunto(s)
Hemoglobinas Anormales/análisis , Talasemia/sangre , Humanos , Italia , Talasemia/epidemiología , Talasemia/genéticaRESUMEN
550 blood specimens from the umbilical cord of newborn babies from Apulia have been screened in order to detect Hb Bart's. The electrophoresis of the haemoglobin by Cellogel (Tris Glycine pH 8.6) carried out on the 550 specimens have revealed in 43 variable quantities of Hb Bart's: 34 cases (6,18%) showed non measurable quota, whereas in the other 9 cases (1,63%) Hb Bart's varied from 2,19% to 26%. The haemoglobin biosynthesis "in vitro" of the baby presenting 26% of Hb Bart's has been reported.