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1.
Dentomaxillofac Radiol ; 53(4): 233-239, 2024 Apr 29.
Artículo en Inglés | MEDLINE | ID: mdl-38466923

RESUMEN

OBJECTIVES: This study evaluated the effect of metal artefact reduction (MAR) level and tube current on the assessment of dental implant positioning relative to the mandibular canal (MC) through cone-beam computed tomography (CBCT). METHODS: Titanium dental implants were placed in dried mandibles at 0.5-mm superior to the MC (group 1/n = 8) and 0.5-mm inside the MC with perforation of the cortex (group 2/n = 10). CBCT scans were obtained with different levels of MAR (off, medium, and high) and 2 tube currents (4 and 8 mA). Four examiners analysed the images and scored the contact between the implant and the MC using a 5-point scale. Sensitivity, specificity, area under receiver operating characteristic curve (ROC), and frequency of scores were calculated. Data were compared with analysis of variance 2-way and Tukey's test and scores with Chi-square test. RESULTS: Specificity and area under ROC curve decreased significantly when MAR level was high compared with MAR-medium and MAR-off. The frequency of score 3 (inconclusive) was the highest, and scores 1 and 5 (definitely no contact and definitely contact, respectively) were the lowest with MAR-high, regardless of the tube current. When MAR was off, there were higher frequencies of scores 1 and 5. CONCLUSIONS: The level of MAR influences the assessment of the relationship between the dental implant and the MC. MAR-high led to lower diagnostic accuracy compared with MAR-medium and off. ADVANCES IN KNOWLEDGE: This article shows that high level of MAR can interfere in the diagnostic of dental implant positioning relative to the MC, decreasing its accuracy.


Asunto(s)
Artefactos , Tomografía Computarizada de Haz Cónico , Implantes Dentales , Tomografía Computarizada de Haz Cónico/métodos , Humanos , Mandíbula/diagnóstico por imagen , Titanio , Sensibilidad y Especificidad , Metales , Técnicas In Vitro
2.
Artículo en Inglés | MEDLINE | ID: mdl-38913866

RESUMEN

OBJECTIVES: The aim of this study was to identify cone-beam computed tomography (CBCT) protocols that offer an optimal balance between effective dose and 3D model for orthognathic virtual surgery planning, using CT as a reference, and to assess whether such protocols can be defined based on technical image quality metrics. METHODS: Eleven CBCT (VISO G7, Planmeca Oy, Helsinki, Finland) scan protocols were selected out of 32 candidate protocols, based on effective dose and technical image quality measurements. Next, an anthropomorphic RANDO SK150 phantom was scanned using these 11 CBCT protocols and 2 CT scanners for bone quantity assessments. The resulting DICOM files were converted into STL models that were used for bone volume and area measurements in the predefined orbital region to assess the validity of each CBCT protocol for VSP. RESULTS: The highest CBCT bone volume and area of the STL models were obtained using normal dose protocol (F2) and ULD protocol (J13) which resulted in 48% and 96% of the mean STL bone volume and 48% and 95% of the bone area measured on CT scanners, respectively. CONCLUSIONS: The optimal normal dose CBCT protocol" F2" offered optimal bone area and volume balance for STL. The optimal CBCT protocol can be defined exhibited similar using CNR and MTF values that were similar with of those of the reference CT scanners'. CBCT scanner with selected protocols can offer a viable alternative to CT scanners for acquiring STL models for VSP at a lower effective dose.

3.
Clin Oral Implants Res ; 34(7): 741-750, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-37246310

RESUMEN

OBJECTIVE: To evaluate the influence of metal artefact reduction (MAR) in the diagnosis of dental implant contact with the mandibular canal (MC) using cone beam computed tomography (CBCT). METHODS: Dental implants were installed with surgical guides in the posterior hemiarches of 10 dry human mandibles: 0.5 mm above to the MC cortex (G1/n = 8) and 0.5 mm inside the MC (G2/n = 10). The experimental set-up was scanned with two CBCT equipment using 85 kV and 90 kV, MAR ON or OFF, and different tube currents (4 mA, 8 mA and 10 mA). Two dentomaxillofacial radiologists (DMFRs) and two dentists (DDS) scored the relation between the dental implant and MC. Descriptive statistics were used to observe the absolute frequency of scores. Sensitivity, specificity and accuracy were calculated considering the known relation between the dental implant and the MC interior. McNemar's test (α = .05) was applied to compare the diagnostic efficacy of MAR ON versus MAR OFF. RESULTS: Overall specificity was higher than sensitivity for both DDS and DMFR (97% vs. 50% and 92.0% vs. 78.0% respectively). There was a significant effect of MAR (p = .031) for DMFR in the case of contact between the dental implant with the MC interior, in which sensitivity decreased with MAR activation from 90% to 40%. DMFR observers showed a better diagnostic performance compared with the DDS observers (accuracy of 84.0% and 71.0%, respectively). CONCLUSIONS: Due to the limited efficacy of MAR, it should not be used when conducting CBCT scans for the evaluation of contact between the implant and the mandibular canal.


Asunto(s)
Implantes Dentales , Procesamiento de Imagen Asistido por Computador , Humanos , Artefactos , Tomografía Computarizada de Haz Cónico/métodos , Mandíbula/diagnóstico por imagen , Mandíbula/cirugía , Canal Mandibular
4.
Clin Oral Investig ; 27(11): 6413-6420, 2023 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-37704914

RESUMEN

AIM: To assess the observed volume of filled C-shaped root canals from different CBCT and micro-CT having nano-CT as a reference. MATERIALS AND METHODS: Twelve extracted mandibular molars with C-shaped root canals were endodontically treated using Reciproc Blue R25 (VDW GMBH, Munich, Germany) in a reciprocating system and filled with gutta-percha (Dentsply Maillefer) and AH Plus sealer (Dentsply DeTrey, Konstanz, Germany). CBCT scans were performed using 3 units-3D Accuitomo 170 (J. Morita, Kyoto, Japan), ProMax 3D Max (Planmeca, Helsinki, Finland), and NewTom VGi EVO (Cefla QR, Verona, Italy)-at two resolution modes: standard and high. Micro-CT and nano-CT scans were also obtained. The volume of all filled C-shaped root canals was obtained using CTAn software (Bruker, Kontich, Belgium), and the blooming artifact, in relation to nano-CT volume, was calculated. The data were evaluated by the Bland-Altman plots and ANOVA two-way for repeated measures (α = 0.05). RESULTS: All CBCT units and micro-CT showed significantly larger observed volume of root canal filling when compared to nano-CT. The blooming artifact of root canal filling in standard resolution was significantly larger than that in high resolution (p < 0.05) in all CBCT units. CONCLUSIONS: Endodontic filling material with AH Plus sealer causes blooming artifacts in CBCT units and micro-CT. CLINICAL RELEVANCE: Considering the anatomical complexity of C-shaped root canals and the challenges associated with endodontic treatment, CBCT is frequently recommended for follow-up evaluations. However, the presence of endodontic filling material can result in blooming artifacts that may potentially impact the accurate diagnosis of endodontic complications.


Asunto(s)
Materiales de Obturación del Conducto Radicular , Cavidad Pulpar , Microtomografía por Rayos X , Preparación del Conducto Radicular , Retratamiento , Gutapercha , Obturación del Conducto Radicular , Tomografía Computarizada de Haz Cónico
5.
Clin Oral Investig ; 26(6): 4457-4466, 2022 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-35166942

RESUMEN

OBJECTIVES: The overall objective of this study was to assess how metal artefacts impact image quality of 13 CBCT devices. As a secondary objective, the influence of scanning protocols and field of view on CBCT image quality with and without metal artefacts was also assessed. MATERIALS AND METHODS: CBCT images were acquired of a dry human skull phantom considering three clinical simulated conditions: one without metal and two with metallic materials (metallic pin and implant). An industrial micro-CT was used as a reference to register the CBCT images. Afterwards, four observers evaluated 306 representative image slices from 13 devices, ranking them from best to worst. Furthermore, within each device, medium FOV and small FOV standard images were compared. General linear mixed models were used to assess subjective perception of examiners on overall image quality in the absence and presence of metal-related artefacts (p < 0.05). RESULTS: Image quality perception significantly differed amongst CBCT devices (p < 0.05). Some devices performed significantly better, independently of scanning protocol and clinical condition. In the presence of metal artefacts, medium FOV standard scanning protocols scored significantly better, while in the absence of metal, small FOV standard yielded the highest performance. CONCLUSIONS: Subjective image quality differs significantly amongst CBCT devices and scanning protocols. Metal-related artefacts may highly impact image quality, with a significant device-dependent variability and only few scanners being more robust against metal artefacts. Often, metal artefact expression may be somewhat reduced by proper protocol selection. CLINICAL RELEVANCE: Metallic objects may severely impact image quality in several CBCT devices.


Asunto(s)
Artefactos , Tomografía Computarizada de Haz Cónico Espiral , Tomografía Computarizada de Haz Cónico/métodos , Humanos , Metales , Percepción , Fantasmas de Imagen
6.
Sensors (Basel) ; 22(22)2022 Nov 09.
Artículo en Inglés | MEDLINE | ID: mdl-36433224

RESUMEN

The aim of this study is to quantitatively evaluate the influence of the duration of ambient light exposure on the image quality of digital radiographs obtained with contemporary phosphor plate (PSP)-based systems. Radiographs of an aluminum step-wedge were obtained using VistaScan and Express systems at five X-ray exposure times: 0.10, 0.20, 0.32, 0.40, and 0.50 s; the resulting dose-area products were, respectively, 21.93, 43.87, 70.19, 87.75, and 109.6 mGycm2. Before PSP read-out, half of the sensitive surface of the PSP plates was exposed to ambient light for 5, 10, 30, 60, and 90 s. The effect of light exposure on brightness, contrast, contrast-to-noise ratio (CNR), signal-to-noise ratio (SNR), and image saturation was compared using ANOVA with the Tukey test (α = 0.05). Ambient light exposure increased brightness and contrast and reduced CNR and SNR in PSP-based radiographs of contemporary digital systems. At the longest X-ray exposure times, ambient light exposure reduced the dark saturation (mean gray values ≤ 1) observed in Express. In conclusion, the negative effects of ambient light observed on the image quality of PSP-based radiographs are directly proportional to the duration of exposure. Clinicians should be aware of such harmful effects when handling and scanning PSP plates in bright environments.


Asunto(s)
Placas Óseas , Radiografía Dental Digital , Radiografía Dental Digital/métodos , Relación Señal-Ruido
7.
J Interv Cardiol ; 2021: 3146104, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34987314

RESUMEN

BACKGROUND: The MAVIG X-ray protective drape (MXPD) has been shown to reduce operator radiation dose during percutaneous coronary interventions (PCI). Whether MXPDs are also effective in reducing operator radiation during chronic total occlusion (CTO) PCI, often with dual access, is unknown. METHODS: We performed a prospective, randomized-controlled study comparing operator radiation dose during CTO PCI (n = 60) with or without pelvic MXPDs. The primary outcomes were the difference in first operator radiation dose (µSv) and relative dose of the first operator (radiation dose normalized for dose area product) at the level of the chest in the two groups. The effectiveness of MXPD in CTO PCI was compared with non-CTO PCI using a patient-level pooled analysis with a previously published non-CTO PCI randomized study. RESULTS: The use of the MXPD was associated with a 37% reduction in operator dose (weighted median dose 26.0 (IQR 10.00-29.47) µSv in the drape group versus 41.8 (IQR 30.82-60.59) µSv in the no drape group; P < 0.001) and a 60% reduction in relative operator dose (median dose 3.5 (IQR 2.5-5.4) E/DAPx10-3 in the drape group versus 8.6 (IQR 4.2-12.5) E/DAPx10-3 in the no drape group; P=0.001). MXPD was equally effective in reducing operator dose in CTO PCI compared with non-CTO PCI (P value for interaction 0.963). CONCLUSIONS: The pelvic MAVIG X-ray protective drape significantly reduced CTO operator radiation dose. This trial is clinically registered with https://www.clinicaltrials.gov (unique identifier: NCT04285944).


Asunto(s)
Oclusión Coronaria , Exposición Profesional , Intervención Coronaria Percutánea , Enfermedad Crónica , Angiografía Coronaria , Oclusión Coronaria/cirugía , Humanos , Exposición Profesional/efectos adversos , Intervención Coronaria Percutánea/efectos adversos , Estudios Prospectivos , Dosis de Radiación , Factores de Riesgo , Resultado del Tratamiento , Rayos X
8.
Clin Oral Investig ; 25(8): 5087-5094, 2021 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-33544197

RESUMEN

OBJECTIVES: To evaluate the effect of cone-beam computed tomography (CBCT) tube current (mA) on the magnitude of artefacts at different distances from titanium or zirconia implants, with and without activation of a proprietary metal artefact reduction (MAR). MATERIAL AND METHODS: Human mandibles were scanned on an OP300 Maxio CBCT unit (Instrumentarium, Tuusula, Finland) before and after the installation of dental implants, with four different tube currents (4 mA, 6.3 mA, 8 mA and 10 mA), with and without activation of proprietary MAR. The effect of mA on the standard deviation (SD) of gray values and contrast to noise ratio (CNR) were assessed in regions of interest located 1.5 cm, 2.5 cm, and 3.5 cm from implants. RESULTS: In the presence of titanium implants, a significant decrease in SD was found by increasing tube current from 4 mA to 6.3 mA or 8 mA. For zirconia implants, 8 mA yielded better results for all distances. MAR improved CNR in the presence of zirconia implants at all distances, whereas no differences were observed with the use of MAR for titanium implants. CONCLUSION: Increased tube current can improve overall image quality in the presence of implants, at all the distances tested. When a zirconia implant is present, such increase in mA should be higher in comparison to that for examinations with titanium implants. Activation of OP300 Maxio proprietary MAR improved image quality only among examinations with zirconia implants. CLINICAL RELEVANCE: Artefact-generating implants are common in the field of view of CBCT examinations. Optimal exposure parameters, such as tube current, ensure high image quality with lowest possible radiation exposure.


Asunto(s)
Artefactos , Implantes Dentales , Tomografía Computarizada de Haz Cónico , Humanos , Titanio , Circonio
9.
Appl Opt ; 58(14): 3748-3753, 2019 May 10.
Artículo en Inglés | MEDLINE | ID: mdl-31158188

RESUMEN

Airplane engines are vital aircraft components, so regular inspections of the engines are required to ensure their stable operation. A dynamic computed tomography (CT) system has been proposed by our group for in situ nondestructive testing of airplane engines, which takes advantage of the rotor's self-rotation. However, static parts of the engines cause blocked artifacts in the reconstructed image, leading to misinterpretations of the condition of engines. In this paper, in order to remove the artifacts produced by the projection of the static parts in CT reconstruction, two deep-learning-based methods are proposed, which use U-Net to perform correction in the projection domain. The projection of static parts can be estimated by a well-trained U-Net and subsequently can be subtracted from the projections of the engine. Finally, the rotor can be reconstructed from the corrected projections. The results shown in this paper indicate that the proposed methods are practical and effective for removing those blocked artifacts and recovering the details of rotating parts, which will, in turn, maximize the utilization of the dynamic CT system for in situ engine tests.

10.
Pediatr Radiol ; 48(3): 308-316, 2018 03.
Artículo en Inglés | MEDLINE | ID: mdl-29143199

RESUMEN

DIMITRA (dentomaxillofacial paediatric imaging: an investigation towards low-dose radiation induced risks) is a European multicenter and multidisciplinary project focused on optimizing cone-beam CT exposures for children and adolescents. With increasing use of cone-beam CT for dentomaxillofacial diagnostics, concern arises regarding radiation risks associated with this imaging modality, especially for children. Research evidence concerning cone-beam CT indications in children remains limited, while reports mention inconsistent recommendations for dose reduction. Furthermore, there is no paper using the combined and integrated information on the required indication-oriented image quality and the related patient dose levels. In this paper, therefore, the authors initiate an integrated approach based on current evidence regarding image quality and dose, together with the expertise of DIMITRA's members searching for a state of the art. The aim of this DIMITRA position statement is to provide indication-oriented and patient-specific recommendations regarding the main cone-beam CT applications in the pediatric field. The authors will review this position statement document when results regarding multidisciplinary approaches evolve, in a period of 5 years or earlier.


Asunto(s)
Tomografía Computarizada de Haz Cónico/métodos , Odontología Pediátrica , Adolescente , Niño , Europa (Continente) , Humanos , Guías de Práctica Clínica como Asunto , Dosis de Radiación , Protección Radiológica
11.
Clin Oral Investig ; 22(4): 1783-1793, 2018 May.
Artículo en Inglés | MEDLINE | ID: mdl-29188451

RESUMEN

OBJECTIVE: The objective of the study was to compare estimates of pediatric cumulative exposure and lifetime attributable risk (LAR) of radiation-induced cancer from dental radiology between cleft palate (CP) subjects and age- and gender-matched controls (non-CP), with and without orthodontic treatment. MATERIALS AND METHODS: The radiation exposure frequency of CP subjects and non-CP controls with and without orthodontic treatment was compared for two-dimensional radiography (intra-oral, panoramic and cephalometric radiography), computed tomography (CT), and cone-beam CT (CBCT) using cumulative radiation dose as an estimate. From this dose estimate, the age- and gender-dependent risk for radiation-induced stochastic effects was calculated for each patient group. RESULTS: CP patients received more radiographic examinations than non-CP controls, with the exception of intra-oral radiographs. The cumulative dose to CP patients was considerably higher (1963 µSv at the age of 20 years) than non-CP patients with (597 µSv) and without (383 µSv) orthodontic treatment, primarily due to the higher frequency of CT scanning. Accordingly, CP patients had a three to five times higher LAR than non-CP patients. CONCLUSIONS: This study suggests a significantly higher lifetime radiation exposure to CP patients than non-CP controls from dental radiographic procedures. Diagnostic benefits from the use of CT and CBCT in children must be justified and appropriate dose optimization strategies implemented. CLINICAL RELEVANCE: The present study indicates the need for proper justification and optimization of pediatric exposures in dentistry, with a special focus on high-risk groups.


Asunto(s)
Fisura del Paladar/diagnóstico por imagen , Exposición a la Radiación , Radiografía Dental , Cefalometría , Niño , Tomografía Computarizada de Haz Cónico , Femenino , Humanos , Masculino , Neoplasias Inducidas por Radiación/etiología , Ortodoncia Correctiva , Radiografía Panorámica , Estudios Retrospectivos , Riesgo , Tomografía Computarizada por Rayos X
12.
Int J Paediatr Dent ; 28(3): 300-309, 2018 May.
Artículo en Inglés | MEDLINE | ID: mdl-29356184

RESUMEN

BACKGROUND: An increasing number of CBCT units and a wide variability of radiation doses have been reported in dentistry lately. AIM: To estimate the effective, cumulative, and organ absorbed doses in children exposed to CBCT over 2 years. DESIGN: A prospective study was conducted in children who underwent CBCT diagnostic imaging with the ProMax3D machine. Organ and effective doses were calculated by Monte Carlo simulation using 5- and 8-year-old pediatric voxel phantoms. Extrapolation procedures were applied to estimate doses for other ages and CBCT protocols used in clinical conditions. RESULTS: The median effective dose was 137.9 µSv, and the median cumulative dose was 231.4 µSv. Statistically significant differences in the effective doses and cumulative doses were found for various indications of CBCT in children (P < 0.001). The median absorbed organ dose for brain and thyroid was significantly higher for the clinical condition that required large FOVs (2.5 mGy and 1.05 mGy, respectively) compared to medium (0.19 and 0.51 mGy) and small FOVs (0.07 and 0.24 mGy; P < 0.05). The radiation dose of salivary glands did not vary significantly with FOV. CONCLUSION: The results revealed the variation of CBCT doses and the influence of FOV size in pediatric exposure.


Asunto(s)
Tomografía Computarizada de Haz Cónico , Método de Montecarlo , Dosis de Radiación , Radiografía Dental , Encéfalo/diagnóstico por imagen , Niño , Preescolar , Tomografía Computarizada de Haz Cónico/instrumentación , Femenino , Humanos , Masculino , Fantasmas de Imagen , Estudios Prospectivos
13.
Eur Radiol ; 27(1): 279-285, 2017 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-27108296

RESUMEN

OBJECTIVES: To estimate the possible reduction of tube output as a function of head size in dental cone-beam computed tomography (CBCT). METHODS: A 16 cm PMMA phantom, containing a central and six peripheral columns filled with PMMA, was used to represent an average adult male head. The phantom was scanned using CBCT, with 0-6 peripheral columns having been removed in order to simulate varying head sizes. For five kV settings (70-90 kV), the mAs required to reach a predetermined image noise level was determined, and corresponding radiation doses were derived. Results were expressed as a function of head size, age, and gender, based on growth reference charts. RESULTS: The use of 90 kV consistently resulted in the largest relative dose reduction. A potential mAs reduction ranging from 7 % to 50 % was seen for the different simulated head sizes, showing an exponential relation between head size and mAs. An optimized exposure protocol based on head circumference or age/gender is proposed. CONCLUSIONS: A considerable dose reduction, through reduction of the mAs rather than the kV, is possible for small-sized patients in CBCT, including children and females. Size-specific exposure protocols should be clinically implemented. KEY POINTS: • Fixed exposure settings in CBCT results in overexposure for smaller patients • For children, considerable dose reduction is possible without compromising image quality • A reduction in mAs is more dose-efficient than a kV reduction • An optimized exposure protocol was proposed based on phantom measurements • This protocol should be validated in a clinical setting.


Asunto(s)
Tomografía Computarizada de Haz Cónico/métodos , Fantasmas de Imagen , Dosis de Radiación , Radiografía Dental/métodos , Adulto , Niño , Femenino , Cabeza/diagnóstico por imagen , Humanos , Masculino
14.
Eur Radiol ; 25(7): 1891-900, 2015 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-25773935

RESUMEN

OBJECTIVES: To evaluate image quality and radiation dose of a state of the art cone beam computed tomography (CBCT) system and a multislice computed tomography (MSCT) system in patients with sinonasal poliposis. METHODS: In this retrospective study two radiologists evaluated 57 patients with sinonasal poliposis who underwent a CBCT or MSCT sinus examination, along with a control group of 90 patients with normal radiological findings. Tissue doses were measured using a phantom model with thermoluminescent dosimeters (TLD). RESULTS: Overall image quality in CBCT was scored significantly higher than in MSCT in patients with normal radiologic findings (p-value: 0.00001). In patients with sinonasal poliposis, MSCT scored significantly higher than CBCT (p-value: 0.00001). The average effective dose for MSCT was 42% higher compared to CBCT (108 µSv vs 63 µSv). CONCLUSIONS: CBCT and MSCT are both suited for the evaluation of sinonasal poliposis. In patients with sinonasal poliposis, clinically important structures of the paranasal sinuses can be better delineated with MSCT, whereas in patients without sinonasal poliposis, CBCT turns out to define the important structures of the sinonasal region better. However, given the lower radiation dose, CBCT can be considered for the evaluation of the sinonasal structures in patients with sinonasal poliposis. KEY POINTS: • CBCT and MSCT are both suited for evaluation of sinonasal poliposis. • Effective dose for MSCT was 42% higher compared to CBCT. • In patients with sinonasal poliposis, clinically important anatomical structures are better delineated with MSCT. • In patients with normal radiological findings, clinically important anatomical structures are better delineated with CBCT.


Asunto(s)
Enfermedades de los Senos Paranasales/diagnóstico por imagen , Senos Paranasales/diagnóstico por imagen , Dosis de Radiación , Tomografía Computarizada por Rayos X/instrumentación , Tomografía Computarizada por Rayos X/métodos , Adolescente , Adulto , Anciano , Tomografía Computarizada de Haz Cónico/instrumentación , Tomografía Computarizada de Haz Cónico/métodos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Variaciones Dependientes del Observador , Fantasmas de Imagen , Estudios Retrospectivos , Dosimetría Termoluminiscente , Adulto Joven
15.
Nephrol Dial Transplant ; 29(5): 1092-6, 2014 May.
Artículo en Inglés | MEDLINE | ID: mdl-24366900

RESUMEN

BACKGROUND: During haemodialysis, anticoagulants are required to prevent clotting in the extracorporeal circuit. Low-molecular weight heparins (LMWH) are frequently used because of the ease of a single injection at the start of dialysis. Disadvantages of LMWH include the lack of a reliable bedside assay for measuring their anticoagulant effect. METHODS: We investigated a bedside test for LMWH activity. The relationship between anti-Xa (chromogenic assay) and Hemonox point-of-care assay was evaluated in 21 dialysis patients (12 men and 9 women) with a median age of 71 years, receiving tinzaparin at the start of a haemodiafiltration session. RESULTS: At the start, before tinzaparin administration, median (interquartile ranges) of Hemonox values were 74 (67-82) s. Thirty minutes after tinzaparin administration, Hemonox values were increased to 496 (360-736) s, followed by a decrease to 149 (135-301) s after 120 min, 102 (97-144) s after 180 min and 92 (83-100) s after 240 min. Corresponding anti-Xa activities were 0 (0-0), 1.12 (0.9-1.29), 0.74 (0.57-0.96), 0.47 (0.31-0.7) and 0.31(0.16-0.49) IU/mL. Hemonox values showed an exponential relation to anti-Xa levels. Interchangeability of tests was shown by Bland-Altman plot. CONCLUSION: Point-of-care Hemonox test is a valuable bedside method for monitoring anti-Xa activity in dialysis patients anticoagulated with tinzaparin.


Asunto(s)
Anticoagulantes/uso terapéutico , Fibrinolíticos/uso terapéutico , Heparina de Bajo-Peso-Molecular/uso terapéutico , Monitoreo Fisiológico , Sistemas de Atención de Punto , Diálisis Renal , Tiempo de Coagulación de la Sangre Total/métodos , Anciano , Anciano de 80 o más Años , Coagulación Sanguínea/efectos de los fármacos , Enfermedad Crónica , Inhibidores del Factor Xa , Femenino , Humanos , Masculino , Persona de Mediana Edad , Curva ROC , Tinzaparina , Tiempo de Coagulación de la Sangre Total/instrumentación
16.
Clin Oral Implants Res ; 24 Suppl A100: 94-9, 2013 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-22168574

RESUMEN

OBJECTIVES: To quantify metal artifacts obtained from a wide range of cone beam computed tomography (CBCT) devices and exposure protocols, to compare their tolerance to metals of different densities, and to provide insights regarding the possible implementation of metal artifact analysis into a QC protocol for CBCT. MATERIALS AND METHODS: A customized polymethyl methacrylate (PMMA) phantom, containing titanium and lead rods, was fabricated. It was scanned on 13 CBCT devices and one multi-slice computed tomography (MSCT) device, including high-dose and low-dose exposure protocols. Artifacts from the rods were assessed by two observers by measuring the standard deviation of voxel values in the vicinity of the rods, and normalizing this value to the percentage of the theoretical maximum standard deviation. RESULTS: For CBCT datasets, artifact values ranged between 6.1% and 27.4% for titanium, and between 10.% and 43.7% for lead. Most CBCT devices performed worse than MSCT for titanium artifacts, but all of them performed better for lead artifacts. In general, no clear improvement of metal artifacts was seen for high-dose protocols, although certain devices showed some artifact reduction for large FOV or high exposure protocols. CONCLUSIONS: Regions in the vicinity of the metal rods were moderately or gravely affected, particularly in the area between the rods. In practice, the CBCT user has very limited possibilities to reduce artifacts. Researchers and manufacturers need to combine their efforts in optimizing exposure factors and implementing metal artifact reduction algorithms.


Asunto(s)
Artefactos , Tomografía Computarizada de Haz Cónico/instrumentación , Metales , Imagenología Tridimensional/instrumentación , Plomo , Fantasmas de Imagen , Dosis de Radiación , Interpretación de Imagen Radiográfica Asistida por Computador , Titanio
17.
Phys Med ; 112: 102639, 2023 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-37441822

RESUMEN

PURPOSE: The purpose of this study was to determine a dedicated conversion formula between dose-area product (DAP) and effective dose (E) for dental CBCT, which incorporates X-ray beam energy as well as geometric factors. METHODS: CBCT exposures of an adult phantom were simulated using PCXMC 2.0 (STUK, Finland). Fifty-seven fields of view (FOV) were included, ranging from Ø4x4cm to Ø21x19cm. Six tube voltages (70 kV to 120 kV), eight combinations of Al (2.5 to 10 mm) and Cu (0 to 0.5 mm) filtration, and four source-isocentre distances (35 to 65 cm) were used, resulting in 10 896 simulated scan protocols. In addition, 10 944 random combinations of scan parameters within the aforementioned ranges were simulated, resulting in 21 840 scan protocols that were used for fitting a formula using multiple linear regression with 8 independent variables. Finally, 2304 random scan protocols were simulated as validation data to evaluate the formula's generalizability. RESULTS: E/DAP ranged between 0.031 µSv/mGy.cm2 and 0.294 µSv/mGy.cm2, with a mean of 0.150 µSv/mGy.cm2. Due to extensive clustering of the E/DAP, three formulas were determined according to FOV categories (Small: <100 cm2, Medium: 100-400 cm2, Large: >400 cm2). The resulting formulas showed mean absolute errors of 7.9%, 4.0% and 3.6%, respectively, for the validation data. CONCLUSION: The new formulas allow for a straightforward, yet accurate, estimation of the effective dose for dental CBCT based on DAP. Further fine-tuning of the model could be achieved by incorporating, for example, bowtie filtration and off-axis beam geometries.


Asunto(s)
Tomografía Computarizada de Haz Cónico , Dosis de Radiación , Tomografía Computarizada de Haz Cónico/métodos , Finlandia , Fantasmas de Imagen
18.
J Imaging ; 9(8)2023 Aug 17.
Artículo en Inglés | MEDLINE | ID: mdl-37623696

RESUMEN

BACKGROUND: The use of cone beam computed tomography (CBCT) in dentistry started in the maxillofacial field, where it was used for complex and comprehensive treatment planning. Due to the use of reduced radiation dose compared to a computed tomography (CT) scan, CBCT has become a frequently used diagnostic tool in dental practice. However, published data on the accuracy of CBCT in the diagnosis of buccal bone level is lacking. The aim of this study was to compare the accuracy of intra-oral radiography (IOR) and CBCT in the diagnosis of the extent of buccal bone loss. METHODS: A dry skull was used to create a buccal bone defect at the most coronal level of a first premolar; the defect was enlarged apically in steps of 1 mm. After each step, IOR and CBCT were taken. Based on the CBCT data, two observers jointly selected three axial slices at different levels of the buccal bone, as well as one transverse slice. Six dentists participated in the radiographic observations. First, all observers received the 10 intra-oral radiographs, and each observer was asked to rank the intra-oral radiographs on the extent of the buccal bone defect. Afterwards, the procedure was repeated with the CBCT scans based on a combination of axial and transverse information. For the second part of the study, each observer was asked to evaluate the axial and transverse CBCT slices on the presence or absence of a buccal bone defect. RESULTS: The percentage of buccal bone defect progression rankings that were within 1 of the true rank was 32% for IOR and 42% for CBCT. On average, kappa values increased by 0.384 for CBCT compared to intra-oral radiography. The overall sensitivity and specificity of CBCT in the diagnosis of the presence or absence of a buccal bone defect was 0.89 and 0.85, respectively. The average area under the curve (AUC) of the receiver operating curve (ROC) was 0.892 for all observers. CONCLUSION: When CBCT images are available for justified indications, other than bone level assessment, such 3D images are more accurate and thus preferred to 2D images to assess periodontal buccal bone. For other clinical applications, intra-oral radiography remains the standard method for radiographic evaluation.

19.
Dentomaxillofac Radiol ; 52(3): 20220387, 2023 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-36688730

RESUMEN

OBJECTIVES: As-low-as-diagnostically-acceptable (ALADA) doses are substantially lower than current diagnostic reference levels. To improve dose management, a reference quality approach was tested in which phantom quality metrics of a clinical ALADA dose reference protocol were used to benchmark potential ALADA dose protocols for various scanner models. METHODS: Spatial resolution, contrast resolution, contrast-to-noise ratio (CNR) and subjective noise and sharpness were evaluated for a clinical ALADA dose reference protocol at 80 kV and 40 mA (CTDIvol 2.66 mGy) and compared with test protocols of two CT scanners at 100 kV and 35 mA (3.08-3.44 mGy), 80 kV and 54-61 mA (2.65 mGy), 80 kV and 40 mA (1.73-1.92 mGy), and 80 kV and 21-23 mA (1.00-1.03 mGy) using different kernels, filtered backprojection and iterative reconstructions. The test protocols with the lowest dose showing quality metrics non-inferior to the reference protocol were verified in a cadaver study by determining the diagnostic accuracy of detection of maxillofacial fractures and CNR of the optical nerve and rectus inferior muscle. RESULTS: 36 different image series were analysed in the phantom study. Based on the phantom quality metrics, potential ALADA dose protocols at 1.73-1.92 mGy were selected. Compared with the reference images, the selected protocols showed non-inferiority in the detection and classification of maxillofacial fractures and non-inferior CNR of orbital soft tissues in the cadaver study. CONCLUSIONS: Reference quality metrics from clinical ALADA dose protocols may be used to guide selection of potential ALADA dose protocols of different CT scanners.


Asunto(s)
Traumatismos Maxilofaciales , Tomografía Computarizada por Rayos X , Humanos , Dosis de Radiación , Tomografía Computarizada por Rayos X/métodos , Fantasmas de Imagen , Cadáver , Interpretación de Imagen Radiográfica Asistida por Computador/métodos
20.
Sci Rep ; 13(1): 4001, 2023 03 10.
Artículo en Inglés | MEDLINE | ID: mdl-36899046

RESUMEN

The aim of this study was to evaluate CBCT exposure protocols and CBCT devices in terms of image quality for the detection of cracks and fine endodontic structures using 3 conditions of metallic artifacts. An anthropomorphic phantom containing teeth with cracks, isthmus, narrow canal, and apical delta was scanned using ten CBCT devices. A reference industrial CT image was used to detect and measure all structures. Three conditions were created: (1) metal-free, (2) 'endo' and (3) 'implant' with metallic objects placed next to the teeth of interest. For each condition, three protocols were selected: medium field of view (FOV) standard resolution, small FOV standard and high resolution. The results showed that only small FOV high-resolution metal-free images from two devices (A and H) were appropriate to visualize cracks. For fine structure identification, the best result was observed for small FOV high resolution. However, the visualization significantly worsened in the presence of metallic artefacts. The ability of CBCT images for visualizing cracks is restricted to certain CBCT devices. Once metallic artefacts are present, crack detection becomes unlikely. Overall, small FOV high-resolution protocols may allow detection of fine endodontic structures as long as there are no high-dense objects in the region of interest.


Asunto(s)
Tomografía Computarizada de Haz Cónico , Tomografía Computarizada de Haz Cónico Espiral , Tomografía Computarizada de Haz Cónico/métodos , Artefactos , Cintigrafía , Fantasmas de Imagen , Metales
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