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1.

Trajectories of clinical characteristics, complications and treatment choices in data-driven subgroups of type 2 diabetes.

Li, Xinyu; Donnelly, Louise A; Slieker, Roderick C; Beulens, Joline W J; 't Hart, Leen M; Elders, Petra J M; Pearson, Ewan R; van Giessen, Anoukh; Leal, Jose; Feenstra, Talitha.

Diabetologia; 2024 Apr 16.

Artículo en Inglés | MEDLINE | ID: mdl-38625583

2.

Phenotype-based targeted treatment of SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes.

Cardoso, Pedro; Young, Katie G; Nair, Anand T N; Hopkins, Rhian; McGovern, Andrew P; Haider, Eram; Karunaratne, Piyumanga; Donnelly, Louise; Mateen, Bilal A; Sattar, Naveed; Holman, Rury R; Bowden, Jack; Hattersley, Andrew T; Pearson, Ewan R; Jones, Angus G; Shields, Beverley M; McKinley, Trevelyan J; Dennis, John M.

Diabetologia; 67(5): 822-836, 2024 May.

Artículo en Inglés | MEDLINE | ID: mdl-38388753

3.

An omics-based machine learning approach to predict diabetes progression: a RHAPSODY study.

Slieker, Roderick C; Münch, Magnus; Donnelly, Louise A; Bouland, Gerard A; Dragan, Iulian; Kuznetsov, Dmitry; Elders, Petra J M; Rutter, Guy A; Ibberson, Mark; Pearson, Ewan R; 't Hart, Leen M; van de Wiel, Mark A; Beulens, Joline W J.

Diabetologia; 67(5): 885-894, 2024 May.

Artículo en Inglés | MEDLINE | ID: mdl-38374450

4.

Genomic editing of metformin efficacy-associated genetic variants in SLC47A1 does not alter SLC47A1 expression.

Kalamajski, Sebastian; Huang, Mi; Dalla-Riva, Jonathan; Keller, Maria; Dawed, Adem Y; Hansson, Ola; Pearson, Ewan R; Mulder, Hindrik; Franks, Paul W.

Hum Mol Genet; 31(4): 491-498, 2022 02 21.

Artículo en Inglés | MEDLINE | ID: mdl-34505146

5.

Pharmacogenetics at scale in real-world bioresources: CYP2C19 and clopidogrel outcomes in UK Biobank.

Bedair, Khaled F; Smith, Blair; Palmer, Colin N A; Doney, Alex S F; Pearson, Ewan R.

Pharmacogenet Genomics; 34(3): 73-82, 2024 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-38179710

6.

Competing risks analysis for neutrophil to lymphocyte ratio as a predictor of diabetic retinopathy incidence in the Scottish population.

Rajendrakumar, Aravind Lathika; Hapca, Simona M; Nair, Anand Thakarakkattil Narayanan; Huang, Yu; Chourasia, Mehul Kumar; Kwan, Ryan Shun-Yuen; Nangia, Charvi; Siddiqui, Moneeza K; Vijayaraghavan, Prathiba; Matthew, Shona Z; Leese, Graham P; Mohan, Viswanathan; Pearson, Ewan R; Doney, Alexander S F; Palmer, Colin N A.

BMC Med; 21(1): 304, 2023 08 10.

Artículo en Inglés | MEDLINE | ID: mdl-37563596

7.

Weight variability and cardiovascular outcomes: a systematic review and meta-analysis.

Massey, Robert J; Siddiqui, Moneeza K; Pearson, Ewan R; Dawed, Adem Y.

Cardiovasc Diabetol; 22(1): 5, 2023 01 09.

Artículo en Inglés | MEDLINE | ID: mdl-36624453

8.

Initiation of glucose-lowering drugs reduces the anticoagulant effect of warfarin-But not through altered drug metabolism in patients with type 2 diabetes.

Dunvald, Ann-Cathrine Dalgård; Nielsen, Flemming; Olsen, Dorte Aalund; Ernst, Martin Thomsen; Donnelly, Louise; Soto-Pedre, Enrique; Kristiansen, Maja Refshauge; Nielsen, Jens Steen; Persson, Frederik; Højlund, Kurt; Madsen, Jonna Skov; Søndergaard, Jens; Pearson, Ewan; Pottegård, Anton; Stage, Tore Bjerregaard.

Br J Clin Pharmacol; 89(8): 2529-2541, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-36967527

9.

Initial Insights into the Genetic Variation Associated with Metformin Treatment Failure in Youth with Type 2 Diabetes.

Srinivasan, Shylaja; Chen, Ling; Udler, Miriam; Todd, Jennifer; Kelsey, Megan M; Haymond, Morey W; Arslanian, Silva; Zeitler, Philip; Gubitosi-Klug, Rose; Nadeau, Kristen J; Kutney, Katherine; White, Neil H; Li, Josephine H; Perry, James A; Kaur, Varinderpal; Brenner, Laura; Mercader, Josep M; Dawed, Adem; Pearson, Ewan R; Yee, Sook-Wah; Giacomini, Kathleen M; Pollin, Toni; Florez, Jose C.

Pediatr Diabetes; 20232023.

Artículo en Inglés | MEDLINE | ID: mdl-38590442

10.

Precision Medicine in Diabetes.

Dawed, Adem Y; Haider, Eram; Pearson, Ewan R.

Handb Exp Pharmacol; 280: 107-129, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-35704097

11.

A roadmap to achieve pharmacological precision medicine in diabetes.

Florez, Jose C; Pearson, Ewan R.

Diabetologia; 65(11): 1830-1838, 2022 11.

Artículo en Inglés | MEDLINE | ID: mdl-35748917

12.

Associations between parental type 2 diabetes risk and offspring birthweight and placental weight: a survival analysis using the Walker cohort.

Sánchez-Soriano, Carlos; Pearson, Ewan R; Reynolds, Rebecca M.

Diabetologia; 65(12): 2084-2097, 2022 12.

Artículo en Inglés | MEDLINE | ID: mdl-35951032

13.

Young-onset diabetes in Asian Indians is associated with lower measured and genetically determined beta cell function.

Siddiqui, Moneeza K; Anjana, Ranjit Mohan; Dawed, Adem Y; Martoeau, Cyrielle; Srinivasan, Sundararajan; Saravanan, Jebarani; Madanagopal, Sathish K; Taylor, Alasdair; Bell, Samira; Veluchamy, Abirami; Pradeepa, Rajendra; Sattar, Naveed; Venkatesan, Radha; Palmer, Colin N A; Pearson, Ewan R; Mohan, Viswanathan.

Diabetologia; 65(6): 973-983, 2022 06.

Artículo en Inglés | MEDLINE | ID: mdl-35247066

14.

The impact of birthweight on subsequent phenotype of type 2 diabetes in later life.

Paulina, Christian; Donnelly, Louise A; Pearson, Ewan R.

Diabet Med; 39(7): e14792, 2022 07.

Artículo en Inglés | MEDLINE | ID: mdl-35030268

15.

The Relationship between AKI and CKD in Patients with Type 2 Diabetes: An Observational Cohort Study.

Hapca, Simona; Siddiqui, Moneeza K; Kwan, Ryan S Y; Lim, Michelle; Matthew, Shona; Doney, Alex S F; Pearson, Ewan R; Palmer, Colin N A; Bell, Samira.

J Am Soc Nephrol; 32(1): 138-150, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-32948670

16.

Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study.

Slieker, Roderick C; Donnelly, Louise A; Fitipaldi, Hugo; Bouland, Gerard A; Giordano, Giuseppe N; Åkerlund, Mikael; Gerl, Mathias J; Ahlqvist, Emma; Ali, Ashfaq; Dragan, Iulian; Festa, Andreas; Hansen, Michael K; Mansour Aly, Dina; Kim, Min; Kuznetsov, Dmitry; Mehl, Florence; Klose, Christian; Simons, Kai; Pavo, Imre; Pullen, Timothy J; Suvitaival, Tommi; Wretlind, Asger; Rossing, Peter; Lyssenko, Valeriya; Legido-Quigley, Cristina; Groop, Leif; Thorens, Bernard; Franks, Paul W; Ibberson, Mark; Rutter, Guy A; Beulens, Joline W J; 't Hart, Leen M; Pearson, Ewan R.

Diabetologia; 64(9): 1982-1989, 2021 09.

Artículo en Inglés | MEDLINE | ID: mdl-34110439

17.

Correction to: The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study.

Koivula, Robert W; Atabaki-Pasdar, Naeimeh; Giordano, Giuseppe N; White, Tom; Adamski, Jerzy; Bell, Jimmy D; Beulens, Joline; Brage, Søren; Brunak, Søren; De Masi, Federico; Dermitzakis, Emmanouil T; Forgie, Ian M; Frost, Gary; Hansen, Torben; Hansen, Tue H; Hattersley, Andrew; Kokkola, Tarja; Kurbasic, Azra; Laakso, Markku; Mari, Andrea; McDonald, Timothy J; Pedersen, Oluf; Rutters, Femke; Schwenk, Jochen M; Teare, Harriet J A; Thomas, E Louise; Vinuela, Ana; Mahajan, Anubha; McCarthy, Mark I; Ruetten, Hartmut; Walker, Mark; Pearson, Ewan; Pavo, Imre; Franks, Paul W.

Diabetologia; 64(1): 260-261, 2021 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-33184701

18.

Dorothy Hodgkin Lecture 2021: Drugs, genes and diabetes.

Pearson, Ewan R.

Diabet Med; 38(12): e14726, 2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-34665880

19.

In a cohort of individuals with type 2 diabetes using the drug sulfasalazine, HbA_1c lowering is associated with haematological changes.

N'Dow, Samira M S; Donnelly, Louise A; Pearson, Ewan R; Rena, Graham.

Diabet Med; 38(9): e14463, 2021 09.

Artículo en Inglés | MEDLINE | ID: mdl-33236391

20.

Precision medicine in diabetes: a Consensus Report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).

Chung, Wendy K; Erion, Karel; Florez, Jose C; Hattersley, Andrew T; Hivert, Marie-France; Lee, Christine G; McCarthy, Mark I; Nolan, John J; Norris, Jill M; Pearson, Ewan R; Philipson, Louis; McElvaine, Allison T; Cefalu, William T; Rich, Stephen S; Franks, Paul W.

Diabetologia; 63(9): 1671-1693, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32556613

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