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1.
Sci Adv ; 6(6): eaax7210, 2020 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-32083175

RESUMEN

The development of nanofibers is expected to foster the creation of outstanding lightweight nanocomposites and flexible and transparent composites for applications such as optoelectronics. However, the reduced length of existing nanofibers and nanotubes limits mechanical strengthening and effective manufacturing. Here, we present an innovative method that produces glass nanofibers with lengths that are, effectively, unlimited by the process. The method uses a combination of a high-power laser with a supersonic gas jet. We describe the experimental setup and the physical processes involved, and, with the aid of a mathematical simulation, identify and discuss the key parameters which determine its distinctive features and feasibility. This method enabled the production of virtually unlimited long, solid, and nonporous glass nanofibers that display outstanding flexibility and could be separately arranged and weaved.

2.
Biomed Mater ; 11(4): 045014, 2016 08 10.
Artículo en Inglés | MEDLINE | ID: mdl-27509353

RESUMEN

Two types of antimicrobial glass fibers containing ZnO and CaO, with diameters ranging from tens of nanometers to 1 µm, were successfully fabricated by a laser spinning technique. The antimicrobial performance was corroborated according to ISO 20743:2013, by using gram-negative (Escherichia coli) and gram-positive (Streptococcus oralis, Streptococcus mutans and Staphylococcus aureus) bacteria, and yeast (Candida krusei) (more than 3 logs of reduction). The metabolic activity and endosomal system of eukaryotic cells were not altered by using eluents of CaO glass submicrometric fibers and ZnO fibers at 1 : 10 dilution as cellular media (viability rates over 70%). A dental material was functionalized by embedding ZnO nanofibers above the percolation threshold (20% wt), creating a three-dimensional (3D) fiber network that added an antimicrobial profile. This new ZnO glass fiber composite is proved non-cytotoxic and preserved the antimicrobial effect after immersion in human saliva. This is the first time that a fiber-reinforced liner with strong antimicrobial-activity has been created to prevent secondary caries. The potential of developing new fiber-reinforced composites (FRCs) with antimicrobial properties opens up an extensive field of dental applications where most important diseases have an infectious origin.


Asunto(s)
Antiinfecciosos/química , Materiales Dentales/química , Vidrio/química , Cementos de Resina/química , Animales , Compuestos de Calcio/química , Candida , Resinas Compuestas , Análisis del Estrés Dental , Escherichia coli , Humanos , Metacrilatos/química , Ratones , Pruebas de Sensibilidad Microbiana , Células 3T3 NIH , Óxidos/química , Saliva/química , Saliva/efectos de los fármacos , Staphylococcus aureus , Streptococcus mutans , Streptococcus oralis , Zinc/química , Óxido de Zinc/química
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