[Trichofolliculoma: a retrospective review of 8 cases]. / Trichofolliculomes : revue rétrospective de 8 cas.

BACKGROUND: Trichofolliculoma is a rare benign tumor consisting of a pilosebaceous follicle hamartoma. While diagnosis of this condition is generally straightforward, fortuitous discovery of an atypical presentation can occur during histological examination of a biopsy or surgical sample. PATIENTS AND METHODS: We report herein on 8 patients aged between 8 and 75 years illustrating the wide spectrum of clinical presentation of this lesion, for which there are numerous differential diagnoses in the event of atypical clinical (lack of central whitish hair plug) or topical features (extra-facial site). In our series, half of the patients displayed a clinically hairless lesion. Moreover, in one case, a patient presented abdominal trichofolliculoma. DISCUSSION: Trichofolliculoma may be under-diagnosed in the general population as illustrated by the frequency of atypical hairless lesions.

[Neonatal cutaneous hematopoiesis disclosing congenital rubella]. / Hématopoïèse cutanée néonatale révélant une rubéole congénitale.

INTRODUCTION: Congenital rubella, which should disappear with widespread vaccination and mandatory obstetrical care, can occur as a purpuric eruption in the newborn. We report a case of blueberry muffin baby. CASE REPORT: An infant delivered after an "uneventful" pregnancy presented a generalized "purpuric" eruption and had axial hypotonia. Histology of a biopsy showed evidence of cutaneous erythropoiesis. The complete workup led to the diagnosis of congenital rubella. DISCUSSION: Cutaneous erythropoiesis is a well defined clinical and histological entity. There are several causes including infection and hematology disorders. Metastasis of a neuroblastoma, which must be eliminated by early biopsy, is the main differential diagnosis. CONCLUSION: Blueberry muffin rash is never idiopathic. The prognosis depends on the cause. Physicians should remember that congenital rubella has not yet been completely eradicated in France.

[Parvovirus B19 atypical acrosyndrome]. / Acrosyndrome atypique à parvovirus B19.

INTRODUCTION: Parvovirus B19 infection is a very polymorphic eruption. We describe a new clinical form. CASE REPORT: A 4-year-old child was hospitalized for a painful acrocyanosis localised at the feet and the tip of the nose, which disappeared without any treatment in three weeks. The screening revealed a parvovirus B19 infection. DISCUSSION: This eruption differs from the classic "gloves and socks syndrome" because of the presence of plantar and nasal painful erythrocyanosis and the young age of the child.

[Bazex paraneoplastic acrokeratosis. Treatment with acitretin]. / Acrokératose paranéoplasique de Bazex. Traitement par acitrétine.

INTRODUCTION: Bazex paraneoplastic acrokeratosis remains a therapeutic challenge when the cancer cannot be treated. We report the third patient in which a complete clearance of the lesions was obtained with oral acitretine. CASE REPORT: A 67 year-old patient had Bazex paraneoplastic acrokeratosis. Despite a complete cancer screening, no cancer was found. A cervical lymph node metastasis was treated with surgery and radiotherapy. Because the cutaneous lesions got worse after this treatment, the patient received oral acitretine. A complete clearing of the lesions was observed within 2 months. DISCUSSION: Only 2 similar cases have been reported to our knowledge. The comparison with these 2 cases supports the efficacy of oral retinoids in this disease. The search and the treatment of the cancer remain compulsory. CONCLUSION: In some definite cases, oral retinoids can be proposed as a treatment of cutaneous lesions in Bazex paraneoplastic acrokeratosis.