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1.
Folia Med Cracov ; 63(3): 133-156, 2023 Oct 30.
Artículo en Inglés | MEDLINE | ID: mdl-38310534

RESUMEN

The objective of this study was to review the current knowledge based on in vitro and in vivo studies, that evaluated the enamel damage connected with removal of metal and ceramic orthodontic brackets taking into account different debonding methods. Brackets fracture was also assessed. The protocol for this study was constructed according to the PRISMA statement. The literature review was performed in MEDLINE via PubMed, Cochrane and Scopus databases in May 2021. The searching was repeated in Journal of Stomatology, Orthodontic Forum and grey literature was screened using Google Scholar. Out of eligible studies 207 were screened by title and abstract, 85 subjected to full-text analysis and 30 were qualified for the research. The prevalence of enamel fracture ranged from 0 to 94.4%. The results of our review do not allow to identify the manual method of debonding that minimizes the risk of enamel damage. Thermal method and laser irradiation reduce the risk of enamel fracture.


Asunto(s)
Fracturas Óseas , Soportes Ortodóncicos , Humanos , Cerámica
2.
Folia Med Cracov ; 63(1): 45-52, 2023 Apr 30.
Artículo en Inglés | MEDLINE | ID: mdl-37406276

RESUMEN

Temporomandibular disorder (TMD) is a disease of multifactorial etiology and a complex of symptoms, related to disorders of the masticatory muscles, temporomandibular joints and the surrounding orofacial structures. One of the main problems in the course of TMD disorders is the systematic increase in the tension of the masticatory muscles (masseter muscles, temporalis and medial and lateral pterygoid muscles), what is the cause of many damages and the development of pathological conditions in the stomatognathic system. The article discusses the differences in the structure of the masticatory and skeletal muscles, as well as the different nature and isoforms of myosin, which determines the much faster generation of contraction in the masticatory muscles and consequently easier generation of excessive, harmful tensions in the masticatory muscles. The article describes the causes of increased tension in the masticatory muscles and methods of their relaxation used in the basic and supportive treatment of temporomandibular disorders. The use of occlusal splints, physiotherapeutic procedures and TMD treatment with botulinum toxin type A were characterized. A role of psychological support and the methods used for patients with TMD were emphasized.


Asunto(s)
Trastornos de la Articulación Temporomandibular , Humanos , Trastornos de la Articulación Temporomandibular/tratamiento farmacológico , Músculos Masticadores , Músculo Masetero , Articulación Temporomandibular , Ferulas Oclusales
3.
Folia Med Cracov ; 63(3): 91-102, 2023 Oct 30.
Artículo en Inglés | MEDLINE | ID: mdl-38310531

RESUMEN

The prevalence of TMD indicates a need to develop new tools that are useful in the case of screening examinations. These methods can support diagnosis at the early stage of the disorder. The purpose of this research was to develop a comprehensive tool that would function as both a database of sounds generated by TMJ and as software which facilitates automated diagnosis. The software would also use the data from the RDC/TMD questionnaire. Such a tool may significantly reduce the time spent by dentists on making manual RDC/TMD diagnoses. Moreover, this solution would enable dentists who do not specialise in TMD to make effective diagnoses. 95 patient took part in the clinical examination: 30 man and 65 females. The mean age of the participants was 33 years. Patients participating in the clinical process were examined according to the Polish version of the RDC/TMD questionnaire (Axis I and Axis II). Subsequently, all subjects were auscultated with an electronic stethoscope. An application has been implemented based on the RDC/TMD diagnostic flow chart. This tool was used for the automated generation of RDC/TMD diagnoses for all patients. As a result of the kind permission and participation of the patients under examination, it was possible to store records of ninety-five people. Each record contains RDC/TMD questionnaire data, auscultation signals and RDC/TMD diagnoses. For the first time, a database was created that has the potential to facilitate further examination. However, the developed system is universal and can therefore be adapted to new DC/TMD criteria.


Asunto(s)
Trastornos de la Articulación Temporomandibular , Síndrome de la Disfunción de Articulación Temporomandibular , Masculino , Femenino , Humanos , Adulto , Trastornos de la Articulación Temporomandibular/epidemiología , Articulación Temporomandibular , Encuestas y Cuestionarios , Polonia
4.
Folia Med Cracov ; 62(4): 45-56, 2022 Dec 29.
Artículo en Inglés | MEDLINE | ID: mdl-36854086

RESUMEN

TMD is a disease within the masticatory system that increases its reach among the society every year in the third and fourth decade of life. The etiology of TMD is complex and it is often difficult to establish the cause in a specific case. The a i m of the study was to determine the impact of TMD on pathomorphological changes within the temporomandibular joints, evaluated in USG examinations and evaluation the assessment of differences in the number of pathological changes between various forms of TMD. MATERIAL AND METHODS: The study material included a group of 386 patients, both sexes, aged 20 to 46 years, who came for prosthetic treatment due to symptoms of TMD. Ultrasound examination of the temporomandibular joints supplemented the clinical diagnosis of TMD in all the subjects. Axis I of the DC/TMD were used. RESULTS: Group I included 116 women and 89 men, group II consisted of 102 women and 79 men. Pathological morphological changes in the temporomandibular joints were found in all the examined patients. The changes in soft tissue structures were significantly increased in group II, but numerous pathomorphological changes were also present in the group of patients with the muscle form of TMD. CONCLUSION: The results of the conducted studies with the use of USG temporomandibular joints revealed numerous pathomorphological changes within the temporomandibular joints. This indicates the usefulness of the USG examination in additional diagnostic tests in the group of patients with TMD.


Asunto(s)
Trastornos de la Articulación Temporomandibular , Articulación Temporomandibular , Femenino , Humanos , Masculino , Examen Físico , Articulación Temporomandibular/diagnóstico por imagen , Trastornos de la Articulación Temporomandibular/diagnóstico por imagen , Adulto Joven , Adulto , Persona de Mediana Edad
5.
Folia Med Cracov ; 62(3): 43-49, 2022 Sep 15.
Artículo en Inglés | MEDLINE | ID: mdl-36309830

RESUMEN

This article characterizes the etiology of temporomandibular disorder with particular emphasis on emotional factors that have a major impact on the development of these dysfunctions and the most common their symptoms. They mainly affect people in the third and fourth decade of life and women predominate among this group of patients. The article analyzes the current literature (Pub Med Database, Scopus and EMBASE) in relation to the conditions in the work environment, which often constitute important causes of emotional tensions, constant state of mental tension and susceptibility to the effects of stressors, which have an impact on the state of functioning of the musculoskeletal system of the masticatory system. Despite the high frequency of temporomandibular disorders, unfortunately only a few studies describe the influence of harmful factors related to the work environment, and own experience (information from the patient's interview) and data from the literature indicate a significant share of these factors in the development of temporomandibular disorder. The relationships and anatomical connections affecting the influence of stressors on the functioning of masticatory muscles and temporomandibular joints are also discussed. In conclusion, it should be stated that the work environment and the emotional tensions generated in it constitute a serious sociological problem and increase the risk of developing and intensify the symptoms of TMD.


Asunto(s)
Trastornos de la Articulación Temporomandibular , Humanos , Femenino , Trastornos de la Articulación Temporomandibular/diagnóstico , Articulación Temporomandibular , Músculos Masticadores , Factores de Riesgo
6.
Folia Med Cracov ; 62(3): 79-90, 2022 Sep 15.
Artículo en Inglés | MEDLINE | ID: mdl-36309833

RESUMEN

TMD is a group of pathological changes including increased tension in the masticatory muscles, pain in the muscles and/or the temporomandibular joints, abnormal range of the mandibular movement or the presence of acoustic symptoms in the joints in the form of clicking or poping. The aim of the project was to compare the effectiveness of two methods of physiotherapeutic rehabilitation, used in adolescent patients with temporomandibular disorders. MATERIAL AND METHODS: The material consisted of 68 patients, aged 14 to 17, of both sexes, generally healthy, who came to the Dental Prosthetics Department for treatment due to pain in the masticatory muscles. Dental examination and diagnostics revealed Ia in all cases in accordance with RDC/TMD protocol. Manual therapy was performed in group I (34 people) and kinesitherapy with massage was performed in group II (34 people). Patients were allocated randomly to both groups. Contraindications were considered for both methods. RESULTS: Within the first study, mean values of pain intensity between group I and group II were not significantly different (6.12 and 6.24 respectively). Within the second study significantly lower VAS scores in both groups have been revealed (0.92 and 0.74 respectively). Results of the first and second study differed significantly in both groups. Similar results were obtained for the maximum abduction of the mandible. CONCLUSIONS: The results of the conducted studies indicate a beneficial effect of the assessed physiotherapeutic procedures in terms of functional rehabilitation of adolescent patients with temporomandibular disorders.


Asunto(s)
Trastornos de la Articulación Temporomandibular , Masculino , Femenino , Humanos , Adolescente , Músculos Masticadores , Articulación Temporomandibular , Mandíbula , Dolor
7.
Folia Med Cracov ; 62(2): 139-146, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36256900

RESUMEN

Chronic pain in the head and face region has a predicted prevalence of 20% in Europe, and is more common in women than men. The etiology of temporomandibular disorder (TMD) is multifactorial, and high levels of psychological stress amplify its symptoms. We were interested in how headache reported in RDC/TMD is associated with stress. Individuals with an average age of 18 years were included in the study. They were all volunteer participants in a research project. Clinical evaluation of each subject was performed using the RDC/TMD dual-axis diagnostic system. All participants filled out the PSS-10 questionnaire. A total of 138 individuals participated in the study, of which 107 were female. Headache was reported by 83 participants (59.4%), with females presenting higher scores on the PSS-10; this was statistically significant. A comparison between PSS-10 questionnaire results and headache level shows insignificant differences. However, the higher the stress level in the participant, the higher the headache score. Females are more susceptible to perceived stress, which can have an effect on TMD.


Asunto(s)
Trastornos de la Articulación Temporomandibular , Masculino , Femenino , Adulto Joven , Humanos , Adolescente , Trastornos de la Articulación Temporomandibular/complicaciones , Trastornos de la Articulación Temporomandibular/diagnóstico , Trastornos de la Articulación Temporomandibular/epidemiología , Cefalea/etiología , Cefalea/complicaciones , Encuestas y Cuestionarios , Estrés Psicológico/complicaciones , Prevalencia
8.
Folia Med Cracov ; 62(2): 121-137, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36256899

RESUMEN

Pain in the masticatory muscles or temporomandibular joints may in some cases be a symptom of other afflictions occurring in this region. The aim of the study was to present the differential diagnosis of temporomandibular disorders (TMD) and other diseases in the craniofacial area, based on review of the literature. Using the key words: "differential diagnosis of TMD", "pain of non-dental origin" and "chronic orofacial pain", PUBMED and Scopus databases were systematically searched for articles in English from 2005 to 2020. Additionally, the PUBMED database was supplementarily reviewed using the keywords "Lyme disease orofacial symptoms" for the English-language articles published in the years 1996-2020. Out of 445 publications from PUBMED and Scopus databases as well as other sources, 57 articles describing the pathogenesis and characteristic symptoms of diseases that may cause pain similar to that occurring in TMD as well as diagnostic methods used in differential diagnosis of TMD were selected for analysis. Dental and jawbones-related conditions, ear and maxillary sinus diseases, as well as ailments of neuropathic and vascular origin, were taken into account. Neoplastic processes taking place in this region and less often occurring diseases caused by viruses, bacteria and parasites were also described. Conclusions. Correct diagnosis of temporomandibular disorders is based on medical history and thorough physical examination, as well as results of additional tests. Pain localized in the head and neck structures may have diverse, sometimes complex aetiology, and may require multidisciplinary treatment. Observation of the patient's behaviour and - in selected cases - the results of additional laboratory tests, also play a significant role.


Asunto(s)
Trastornos de la Articulación Temporomandibular , Humanos , Diagnóstico Diferencial , Trastornos de la Articulación Temporomandibular/diagnóstico , Dolor Facial/diagnóstico , Dolor Facial/etiología , Articulación Temporomandibular , Músculos Masticadores
9.
Folia Med Cracov ; 61(2): 25-33, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34510162

RESUMEN

Temporomandibular disorders includes abnormalities of the masticatory muscles, temporomandibular joints and the surrounding structures. The aim of the study was to carry out a retrospective assessment of the frequency of the pain form of TMD based on the analysis of medical records of patients treated at the Prosthodontic Department at Jagiellonian University in Kraków. MATERIAL AND METHODS: The study included the results of a medical history and a clinical examination of patients, who came for consultation at the Prosthodontics Department at Jagiellonian University in Krakow, due to pain of the masticatory muscles or/and TMJ and painless symptom of TMD like limitation of the jaw movements and joints' sounds. Out of all the analyzed results of the examination of treated patients, a group of patients with a painless and painful TMD was selected. RESULTS: The study involved the results of a detailed specialized functional examination of 334 patients (210 women and 124 men), ranging in age from 41 to 68 years. Analysis of the results of clinical examinations conducted in all patients revealed that 161 had the painless form - SG (99 women and 62 men) and 173 patients had the pain form of the TMD - CG (111 women and 62 men). In the CG 104 patients reported mostly pain in the masticatory muscles, while the remaining (69 patients) had a history of pain in one or simultaneously two TMJs. CONCLUSION: The analysis of the patients forms allows to conclude that more than half of patients seeking help are patients with the painful form of the TMD and these abnormalities occur more frequently in women than in men.


Asunto(s)
Trastornos de la Articulación Temporomandibular , Adulto , Anciano , Femenino , Humanos , Masculino , Músculos Masticadores , Persona de Mediana Edad , Dolor , Estudios Retrospectivos , Articulación Temporomandibular , Trastornos de la Articulación Temporomandibular/epidemiología
10.
Folia Med Cracov ; 61(1): 57-65, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34185768

RESUMEN

Temporomandibular disorders (TMD) encompass a diverse group of abnormalities in the functioning of the masticatory muscles, temporomandibular joints, and surrounding structures within the facial skull. One of the important etiological factors, contributing to the development of TMD are psychoemotional disorders, which include: depression, dysthymia, personality disorders, panic attacks as well as states and anxiety neuroses.The aim of the study was to carry out a retrospective evaluation of the occurrence of psychoemotional disorders reported in the application form of medical interview of patients treated at the Consulting Room of Temporomandibular Disorders in Dental Institute (University Dental Clinic) for TMD. The research material consisted of a subjective survey according to the protocol of the RDC/TMD questionnaire, axis II, of the 360 patients (224 women, 136 men), aged 19 to 43 who came to the University Dental Clinic in Krakow due to TMD management. Result: The results of the conducted studies indicate the common occurrence of emotional disorders in the group of patients treated for TMD, both in the group of muscular and joint form of dysfunctions. The most often the patients selected: loss of sexual interest or pleasure, crying easily, feeling lonely, indifference to every- thing and feeling of worthlessness. These aspects show a significant influence of emotional factors on TMD. Conclusion: The results of the conducted research indicate a significant frequencies of psychological and emotional disturbances reported in a survey among patients with TMD.


Asunto(s)
Trastornos de la Articulación Temporomandibular , Adulto , Femenino , Humanos , Masculino , Músculos Masticadores , Estudios Retrospectivos , Encuestas y Cuestionarios , Articulación Temporomandibular
11.
Folia Med Cracov ; 60(2): 123-134, 2020 09 28.
Artículo en Inglés | MEDLINE | ID: mdl-33252600

RESUMEN

INTRODUCTION: Temporomandibular disorders (TMD) are the second most common cause of chronic pain in the human musculoskeletal system. The triad of symptoms of TMD includes: pain within the temporomandibular joint (TMJ), limitation of its mobility and capitations. The aim of the study was to present the methods of physiotherapy and to assess its effectiveness in patients with hypomobility of temporomandibular joints. MATERIAL AND METHODS: 44 patients (40.2 ± 10.6 years) were examined for signs of TMD using the Manual Functional Analysis of masticatory system (MFA) questionnaire due to DC/TMD. In the above group, 20 patients showed hypomobility of TMJs and myofascial pain. They underwent a 3-week physiotherapy consisting of manual therapy and exercises. In the study group, linear measurements of TMJs mobility and palpation of selected masticatory muscles were performed. Pain was assessed before and after 3 weeks of therapy according to Numerical Rating Scale (NRS). Statistical processing of the data was done with STATISTICA 13 and was conducted considering significance at a p-value <0.05. RESULTS: Significant improvement in TMJ's mobility, which increased on average by 6.6 mm (p = 0.0005) and reducing of pain, a decrease of 3 points on average on the NRS Scale (p = 0.00002) were achieved. CONCLUSIONS: The applied physiotherapy algorithm, including manual therapy and exercises of masticatory muscles, is effective in the case of improvement TMJ's range of motion and reduction of pain in patients with hypomobility of TMJ's.


Asunto(s)
Músculos Masticadores/fisiopatología , Modalidades de Fisioterapia/normas , Guías de Práctica Clínica como Asunto , Rango del Movimiento Articular/fisiología , Trastornos de la Articulación Temporomandibular/rehabilitación , Articulación Temporomandibular/fisiopatología , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Polonia , Trastornos de la Articulación Temporomandibular/diagnóstico , Resultado del Tratamiento
12.
Folia Med Cracov ; 60(1): 75-83, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32658214

RESUMEN

Temporomandibular disorders (TMD) is one of the most common problem in contemporary dentistry. It is a term covering dysfunction of the masticatory muscles and the temporomandibular joints. Patients are suffering from severe pain, followed by limited mandibular opening and sounds in the temporomandibular joints during jaw movement. TMD influences the quality of life because the symptoms can become chronic and difficult to manage. Radiofrequency waves (RF) are electromagnetic waves with low energy and high frequency. They provide pain relief without causing significant damage to the nervous tissue. The RF therapy is commonly used for physiotherapeutic treatment of skeletal muscle relaxation, as a supportive therapy. The rehabilitation effect of these waves is based on diathermy by means of high-voltage quick alternating current. RF has also found application in physical therapy, as a therapeutic tool for various types of chronic pain syndromes. The aim of this literature review is to show the beneficial effect of radiofrequency waves on the pain of the masticatory muscles in the course of TMD.


Asunto(s)
Músculos Masticadores/fisiopatología , Terapia por Radiofrecuencia/métodos , Trastornos de la Articulación Temporomandibular/radioterapia , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad
13.
Folia Med Cracov ; 60(2): 43-54, 2020 09 28.
Artículo en Inglés | MEDLINE | ID: mdl-33252594

RESUMEN

INTRODUCTION: Dentin hypersensitivity is a painful clinical condition. The frequency of its occurrence varies from 8 to 57%, depending on tested group and different methods of investigations. Recommended desensitizing agents have different mechanism of action and effectiveness. We are still looking for solutions that will improve their effectiveness and simultaneously allow for wider use of e.g. as a base material, counteracting postoperative hypersensitivity, reducing marginal microleakage. The aim of the study was to assess the effect of a selected desensitizing agent occluding dentin tubules with calcium hydroxyapatite on marginal microleakage formation of a class V composite restorations subjected to thermocycles. MATERIALS AND METHODS: In study it was used 40 molars and premolars, which were alternately assigned into two groups. In both groups standardized cavities were prepared. In the study group (study group - SG) before application of bonding agent Teethmate Desensitizer (f. Kuraray, Noritake Dental Inc., Okayama, Japan) was used. In the control group (control group - CG) OptiBond All-in-one (f. Kerr, Bioggio, Switzerland) bonding agent was used and cavities were filled using composite material Gradia Direct (f. GC Europe N.V., Leuven, Belgium). After storage in saline, teeth were subjected to 600 thermocycles, passive dye penetration test was done, teeth were cut in the area of filling, according to its long axis. Under light microscope magnification value of microleakage was measured and marginal microleakage rate (M) was counted. The results of the tests were statistically analyzed using the package STATISTICA 12.0 (StatSoft, USA). RESULTS: The average value of M for the SG group was 0.46 (min 0.05, max 0.76, SD 0.226) and for CG was 0.22 (min 0, max 0.74, SD 0.235). The differences between M values were statistically significant (p = 0.0094). CONCLUSION: A reduction in the number of retention sites for the bonding system, facilitates the formation of microleakage in the experimental conditions and reduces the degree of adhesion of the composite material to the hard tissues of the tooth.


Asunto(s)
Resinas Acrílicas/efectos adversos , Resinas Compuestas/efectos adversos , Filtración Dental/tratamiento farmacológico , Cavidad Pulpar/cirugía , Restauración Dental Permanente/efectos adversos , Desensibilizantes Dentinarios/uso terapéutico , Sensibilidad de la Dentina/tratamiento farmacológico , Recubrimientos Dentinarios/efectos adversos , Durapatita/efectos adversos , Poliuretanos/efectos adversos , Adulto , Anciano , Anciano de 80 o más Años , Filtración Dental/etiología , Restauración Dental Permanente/métodos , Femenino , Humanos , Masculino , Persona de Mediana Edad
14.
Folia Med Cracov ; 59(3): 113-122, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31891364

RESUMEN

Significant impact factor and psycho-emotional stress in the etiology of dysfunction indicate the need of the routine approach in the treatment of patients with temporomandibular joint disorders to be changed. The aim of the study was to obtain data, documented test results as to the effciency of progressive muscle relaxation in the treatment of pain caused by temporomandibular joint disorders, as a supplement to previous methods using occlusal splint and other physical therapies. The study included 100 patients of both sexes, aged from 20 to 35 years who were diagnosed with pain due to temporomandibular joint disorders accompanied with high muscle tension of musticatory muscles which were treatment by relaxation therapy. All patients underwent physical examination, specialized functional examination of the masticatory system in accordance with the Polish version of the study RDC/TMD (The Research Diagnostic Criteria of Temporomandibular Disorders, Axis I - physical assessment, Axis II - assessment of psychosocial status and pain - related disability) and assessment of psycho emotional factor and stress, based on the survey developed for their own purpose. The results of the research were obtained using specialized statistical package "R" i386 3.2.3. The results of examinations a er relaxation therapy showed a significant reduction in the intensity of myofascial pain in all patients. Progressive muscle relaxation can be successfully used as an supportive therapy treatment of patient with dysfunction.


Asunto(s)
Relajación Muscular/fisiología , Manejo del Dolor/métodos , Terapia por Relajación/métodos , Trastornos de la Articulación Temporomandibular/fisiopatología , Trastornos de la Articulación Temporomandibular/terapia , Adulto , Femenino , Humanos , Masculino , Polonia/epidemiología , Encuestas y Cuestionarios , Trastornos de la Articulación Temporomandibular/epidemiología , Adulto Joven
15.
Int J Mol Sci ; 18(4)2017 Mar 27.
Artículo en Inglés | MEDLINE | ID: mdl-28346382

RESUMEN

The aim of the study was to analyse the disturbances of the oro-pharyngeal swallowing phase of dysphagia in amyotrophic lateral sclerosis (ALS) patients with the use of specific manometric measurements and to evaluate their plausible association with the duration of the disease. Seventeen patients with ALS were evaluated with manometric examinations of the oral and pharyngeal part of the gastrointestinal tract. Tests were carried out by using the oesophageal balloon-based method with four balloon transducers located 5 cm away from each other. The following manometric parameters were analysed: the base of tongue contraction (BTC) and the upper oesophageal sphincter pressure (UESP), and the hypopharyngeal suction pump (HSP) as well as the oro-pharyngeal, pharyngeal and hypopharyngeal transit time and average pharyngeal bolus velocity (oropharyngeal transit time (OTT), pharyngeal transit time (PTT), hypopharyngeal transit time (HTT) and average pharyngeal bolus velocity (APBV), respectively). Manomatric examinations during swallowing in patients with ALS showed significant weakness of BTC, a decrease of HSP and a decrease of the velocity of bolus transit inside the pharynx which were particularly marked between the first and the third examination. Manometric examinations of the oro-pharyngeal part of the gastrointestinal tract are useful and supportive methods in the analysis of swallowing disturbances in ALS patients.


Asunto(s)
Esclerosis Amiotrófica Lateral/fisiopatología , Deglución/fisiología , Adulto , Anciano , Esclerosis Amiotrófica Lateral/diagnóstico , Estudios de Casos y Controles , Esófago/fisiología , Femenino , Tracto Gastrointestinal/diagnóstico por imagen , Humanos , Masculino , Manometría , Persona de Mediana Edad , Índice de Severidad de la Enfermedad , Lengua/fisiología , Adulto Joven
16.
Int J Mol Sci ; 18(6)2017 May 24.
Artículo en Inglés | MEDLINE | ID: mdl-28538694

RESUMEN

Previous studies have shown that ghrelin exhibits a protective and therapeutic effect in the gut. The aim of the present study was to examine whether administration of ghrelin affects the course of acetic acid-induced colitis and to determine what is the role of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) in this effect. In sham-operated or hypophysectomized male Wistar rats, colitis was induced by enema with 1 mL of 3% solution of acetic acid. Saline or ghrelin (given at the dose of 8 nmol/kg/dose) was administered intraperitoneally twice a day. Seven days after colitis induction, rats were anesthetized and the severity of the colitis was assessed. Treatment with ghrelin reduced the area of colonic mucosa damage in pituitary-intact rat. This effect was associated with increase in serum levels of GH and IGF-1. Moreover, administration of ghrelin improved blood flow in colonic mucosa and mucosal cell proliferation, as well as reduced mucosal concentration of proinflammatory interleukin-1ß (IL-1ß) and activity of myeloperoxidase. Hypophysectomy reduced serum levels of GH and IGF-1 and increased the area of colonic damage in rats with colitis. These effects were associated with additional reduction in mucosal blood follow and DNA synthesis when compared to pituitary-intact rats. Mucosal concentration of IL-1ß and mucosal activity of myeloperoxidase were maximally increased. Moreover, in hypophysectomized rats, administration of ghrelin failed to affect serum levels of GH or IGF-1, as well as the healing rate of colitis, mucosal cell proliferation, and mucosal concentration of IL-1ß, or activity of myeloperoxidase. We conclude that administration of ghrelin accelerates the healing of the acetic acid-induced colitis. Therapeutic effect of ghrelin in experimental colitis is mainly mediated by the release of endogenous growth hormone and IGF-1.


Asunto(s)
Colitis/tratamiento farmacológico , Ghrelina/uso terapéutico , Hormona del Crecimiento/metabolismo , Factor I del Crecimiento Similar a la Insulina/metabolismo , Ácido Acético , Animales , Colitis/sangre , Colitis/inducido químicamente , Colitis/patología , Colon/efectos de los fármacos , Colon/patología , Ghrelina/farmacología , Hormona del Crecimiento/análisis , Factor I del Crecimiento Similar a la Insulina/análisis , Mucosa Intestinal/efectos de los fármacos , Mucosa Intestinal/patología , Masculino , Ratas Wistar
17.
Folia Med Cracov ; 57(3): 57-65, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-29263455

RESUMEN

The temporomandibular joint pain, which occurs in the course of temporomandibular joint dysfunction, is one of the main clinical problems in the treatment of joint disc displacement. The aim of the study was to evaluate changes in temporomandibular joints pain in treatment supporting disc displacement without reduction using intra-articular injection of hyaluronic acid and platelet-rich plasma. MATERIAL AND METHODS: The study consisted of a group of 60 patients, aged 35-49, who reported for treatment, because of pain in the preauricural area. The functional examination stated disk dicplacement without reduction, along with the accompanying pain of temporomandibular joints. Patients were treated between January 2015 and February 2017. They were divided into two groups of 30 persons. The intraarticular injection of hyaluronic acid was administered in the I-test group, and the injection of platelet-rich plasma in the control group. This treatment was carried out parallel to the use of repositioning splits. THE RESULTS: Analysis of regression of symptoms other than intensity of pain during the treatment, evaluated in this study shows a decrease of individual symptoms, but the results of the regression of pain between two groups did not differ statistically significantly, because "p" is bigger than 0.05. CONCLUSION: The results of the research show the clinical benefits of application of hyaluronic acid and plate rich plasma in the treatment of temporomandibular joint dysfunction.


Asunto(s)
Dolor Facial/tratamiento farmacológico , Ácido Hialurónico/administración & dosificación , Plasma Rico en Plaquetas/metabolismo , Trastornos de la Articulación Temporomandibular/tratamiento farmacológico , Adulto , Anciano , Dolor Facial/etiología , Femenino , Humanos , Inyecciones Intraarticulares , Masculino , Persona de Mediana Edad , Dimensión del Dolor , Trastornos de la Articulación Temporomandibular/complicaciones , Resultado del Tratamiento
18.
Folia Med Cracov ; 57(4): 71-81, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-29337979

RESUMEN

Recent years have shown an increase in the number of patients reporting for treatment of pain due to musculoskeletal joint, associated with temporomandibular joint dysfunction. Therefore, studies were undertaken, aimed at analyzing the symptoms of the dysfunction, because of which patients come to the prosthetic treatment. Aim of the thesis: The aim of the study was a retrospective analysis of symptoms of temporomandibular joint dysfunction reported by patients diagnosed with this problem. MATERIAL AND METHODS: The research material was a retrospective medical records of 120 patients, aged 19 to 45 years who have taken prosthetic treatment due to temporomandibular joint dysfunction in the Consulting Room in Prosthetics Department in Kraków, from June 2015 to December 2016. During the test patients, in addition to interviewing a physician, completed a personal survey in their own study. The material has been divided into I group of patients who reported pain form of dysfunction and II group, who had no symptoms of pain within the stomatognatic system. The analysis covered type of symptoms, the share of local factors (para-functions) and systemic, as well as the time a er which the patients reported for the treatment of functional disorders since the appearance of the first symptoms. RESULTS AND CONCLUSIONS: Analysis of the research material showed that the main reason for reporting patients was pain in one or both temporal joints of significant intensity (5 to 8 in VAS scale,) accompanied by acoustic symptoms. A large group of questioners reported problems with the range of jaw movement and head and face pain, as well as subjective symptoms from the auditory, sight, neck, neck and shoulder areas.


Asunto(s)
Estado de Salud , Dolor/etiología , Autoinforme , Trastornos de la Articulación Temporomandibular/complicaciones , Síndrome de la Disfunción de Articulación Temporomandibular/complicaciones , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Dolor de Cuello/etiología , Polonia , Estudios Retrospectivos , Encuestas y Cuestionarios , Adulto Joven
19.
J Headache Pain ; 17: 29, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27011213

RESUMEN

BACKGROUND: Temporomandibular joint dysfunction are often accompanied by symptoms of headache such as tension-type headache which is the most frequent spontaneous primary headache. Masseter muscle pain is commonly reported in this group. The purpose of the study was to assess the efficiency of intramuscular botulinum toxin type A injections for treating masseter muscle pain in patients with temporomandibular joint dysfunction and tension-type headache. METHODS: This prospective outcome study consisted of 42 subjects of both genders aged 19-48 years diagnosed with masseter muscle pain related to temporomandibular joint dysfunction and tension-type headache. The subjects were treated by the intramuscular injection of 21 U (mice units) of botulinum toxin type A (Botox, Allergan) in the area of the greatest cross-section surface of both masseter bellies. Pain intensity was evaluated using visual analogue scale (VAS) and verbal numerical rating scale (VNRS) 1 week before the treatment and 24 weeks after the treatment. The obtained data were analyzed using the Wilcoxon matched pairs test (p ≤ 0,005). RESULTS: The results of this study showed a decrease in the number of referred pain episodes including a decrease in pain in the temporal region bilaterally, a reduction of analgesic drugs intake as well as a decrease in reported values of VAS and VNRS after injections (p = 0,000). CONCLUSIONS: The intramuscular botulinum toxin type A injections have been an efficient method of treatment for masseter muscle pain in patients with temporomandibular joint dysfunction and tension-type headache.


Asunto(s)
Toxinas Botulínicas Tipo A/uso terapéutico , Mialgia/tratamiento farmacológico , Fármacos Neuromusculares/uso terapéutico , Síndrome de la Disfunción de Articulación Temporomandibular/tratamiento farmacológico , Cefalea de Tipo Tensional/tratamiento farmacológico , Adulto , Toxinas Botulínicas Tipo A/farmacología , Femenino , Humanos , Inyecciones Intramusculares , Masculino , Músculo Masetero/efectos de los fármacos , Persona de Mediana Edad , Fármacos Neuromusculares/farmacología , Dimensión del Dolor , Estudios Prospectivos , Resultado del Tratamiento , Adulto Joven
20.
J Clin Med ; 13(3)2024 Feb 04.
Artículo en Inglés | MEDLINE | ID: mdl-38337596

RESUMEN

(1) Background: Dislocations of articular disk can occur as a result of parafunctions in the Temporo Mandibular Joint (TMJ), which limits the opening of the mandible and other movements. The aim of this study was to evaluate the effectiveness of rehabilitation in patients with disk displacement of the TMJ. A total of 327 subjects with Temporo Mandibular Disorders underwent stomathognatic physiotherapy. (2) Methods: Based on the results obtained by a manual functional analysis, 35 patients who were identified with articular disk locking (disk displacement without reduction) were included in the study. The study group (N = 35) was subjected to passive repositioning of the articular disk, reposition splints, and physiotherapy. The patient's TMJs were then examined before the therapy, immediately after the therapy, and during the follow-up visit 3-6 weeks after the therapy. The Diagnostic Criteria for the Most Common Intra-articular Temporomandibular Disorders was used to evaluate the effects of rehabilitation on the patients' range of motions and the Numeric Pain Rating Scale (NPRS). For the statistical analysis, Pearson's r correlation coefficient test and Wilcoxon signed-rank test were used. (3) Results: The results showed a significant improvement in the range of motion of the mandible movements. The level of improvement was dependent on the time from the incident until undergoing rehabilitation. (4) Conclusions: The stomatognathic physiotherapy applied increased the range of motion of the mandible and reduced pain levels to the expected range.

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