1.
Euro Surveill
; 29(3)2024 Jan.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38240061
RESUMEN
We conducted a multicentre hospital-based test-negative case-control study to measure the effectiveness of adapted bivalent COVID-19 mRNA vaccines against PCR-confirmed SARS-CoV-2 infection during the Omicron XBB lineage-predominant period in patients aged ≥ 60 years with severe acute respiratory infection from five countries in Europe. Bivalent vaccines provided short-term additional protection compared with those vaccinated > 6 months before the campaign: from 80% (95%â¯CI: 50â¯toâ¯94) for 14-89 days post-vaccination, 15% (95%â¯CI: -12â¯toâ¯35) at 90-179 days, and lower to no effect thereafter.