Detalles de la búsqueda
1.
Quantitative Proteomics in Translational Absorption, Distribution, Metabolism, and Excretion and Precision Medicine.
Pharmacol Rev;
74(3): 769-796, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35738681
2.
Effect of Cimetidine on Metformin Pharmacokinetics and Endogenous Metabolite Levels in Rats.
Drug Metab Dispos;
52(2): 86-94, 2024 Jan 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-38049999
3.
Quantitative Proteomics for Translational Pharmacology and Precision Medicine: State of The Art and Future Outlook.
Drug Metab Dispos;
2024 May 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-38821856
4.
Differential tissue abundance of membrane-bound drug metabolizing enzymes and transporter proteins by global proteomics.
Drug Metab Dispos;
2024 Apr 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-38641346
5.
Ontogeny of Human Liver Aldehyde Oxidase: Developmental Changes and Implications for Drug Metabolism.
Mol Pharm;
21(6): 2740-2750, 2024 Jun 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38717252
6.
Promiscuity and Quantitative Contribution of UGT2B17 in Drug and Steroid Metabolism Determined by Experimental and Computational Approaches.
J Chem Inf Model;
64(2): 483-498, 2024 Jan 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-38198666
7.
Global Proteomics Analysis of Lysophosphatidic Acid Signaling in PC-3 Human Prostate Cancer Cells: Role of CCN1.
Int J Mol Sci;
25(4)2024 Feb 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38396744
8.
The Plasma Membrane Monoamine Transporter is Highly Expressed in Neuroblastoma and Functions as an mIBG Transporter.
J Pharmacol Exp Ther;
387(3): 239-248, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37541765
9.
Quantification of Accurate Composition and Total Abundance of Homologous Proteins by Conserved-Plus-Surrogate Peptide Approach: Quantification of UDP Glucuronosyltransferases in Human Tissues.
Drug Metab Dispos;
51(3): 285-292, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36446609
10.
Innovations, Opportunities, and Challenges for Predicting Alteration in Drug-Metabolizing Enzyme and Transporter Activity in Specific Populations.
Drug Metab Dispos;
51(12): 1547-1550, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37775331
11.
Relevance of Human Aldoketoreductases and Microbial ß-Glucuronidases in Testosterone Disposition.
Drug Metab Dispos;
51(4): 427-435, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36623880
12.
Dissecting Parameters Contributing to the Underprediction of Aldehyde Oxidase-Mediated Metabolic Clearance of Drugs.
Drug Metab Dispos;
51(10): 1362-1371, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37429730
13.
Characterization of Xenobiotic and Steroid Disposition Potential of Human Placental Tissue and Cell Lines (BeWo, JEG-3, JAR, and HTR-8/SVneo) by Quantitative Proteomics.
Drug Metab Dispos;
51(8): 1053-1063, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37164652
14.
Quantitative Characterization of Clinically Relevant Drug-Metabolizing Enzymes and Transporters in Rat Liver and Intestinal Segments for Applications in PBPK Modeling.
Mol Pharm;
20(3): 1737-1749, 2023 03 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36791335
15.
Involvement of the p38/MK2 Pathway in MCLR Hepatotoxicity Revealed through MAPK Pharmacological Inhibition and Phosphoproteomics in HepaRG Cells.
Int J Mol Sci;
24(13)2023 Jul 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37446360
16.
Ontogeny of Scaling Factors for Pediatric Physiology-Based Pharmacokinetic Modeling and Simulation: Microsomal Protein Per Gram of Liver.
Drug Metab Dispos;
50(1): 24-32, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34686522
17.
Interindividual Variability and Differential Tissue Abundance of Mitochondrial Amidoxime Reducing Component Enzymes in Humans.
Drug Metab Dispos;
50(3): 191-196, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34949674
18.
Comparison of Tissue Abundance of Non-Cytochrome P450 Drug-Metabolizing Enzymes by Quantitative Proteomics between Humans and Laboratory Animal Species.
Drug Metab Dispos;
50(3): 197-203, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34969659
19.
Dimethandrolone, a Potential Male Contraceptive Pill, is Primarily Metabolized by the Highly Polymorphic UDP-Glucuronosyltransferase 2B17 Enzyme in Human Intestine and Liver.
Drug Metab Dispos;
50(12): 1493-1500, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36184078
20.
Exploration of the Plausible Mechanism of Ethambutol Induced Ocular Toxicity by Using Proteomics Informed Physiologically Based Pharmacokinetic (PBPK) Modeling.
Pharm Res;
39(4): 677-689, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-35301670