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1.
Health Qual Life Outcomes ; 10: 46, 2012 May 06.
Artículo en Inglés | MEDLINE | ID: mdl-22559816

RESUMEN

BACKGROUND: To assess health- related quality of life (HRQOL) with SF-12 and SF-36 and compare their abilities to predict mortality in chronic dialysis patients, after adjusting for traditional risk factors. METHODS: The Short-Form Health Survey (SF-36) with the embedded SF-12 was applied in 301 dialysis patients cross-sectionally. Physical and mental component summary (PCS-36, MCS-36, PCS-12, and MCS-12) scores were calculated. Clinical and demographic data were collected. Mortality (followed for up to 4.5 years) was analyzed with Kaplan Meier plots and Cox proportional hazards, after censoring for renal transplantation. Exclusion factors were observation time <2 months (n = 21) and missing component summary scores (n = 10 for SF-36; n = 28 for SF-12), thus 252 patient were included in the analyses. RESULTS: In 252 patients (60.2 ± 15.5 years, 65.9% males, dialysis vintage 9.0, IQR 5.0-23.0 months), mortality during follow-up was 33.7%.(85 deaths). Significant correlations were observed between PCS-36 and PCS-12 (ρ = 0.93, p < 0.001) and between MCS-36 and MCS-12 (ρ = 0.95, p < 0.001). Mortality rate was highest in patients in the lowest quartile of PCS-12 (χ² = 15.3, p = 0.002) and PCS-36 (χ² = 16.7, p = 0.001). MCS was not associated with mortality. Adjusted hazard ratios for mortality were 2.5 (95% CI 1.0-6.3, PCS-12) and 2.7 (1.1 - 6.4, PCS-36) for the lowest compared with the highest ("best perceived") quartile of PCS. CONCLUSION: Compromised HRQOL is an independent predictor of poor outcome in dialysis patients. The SF-12 provided similar predictions of mortality as SF-36, and may serve as an applicable clinical tool because it requires less time to complete.


Asunto(s)
Indicadores de Salud , Encuestas Epidemiológicas/normas , Calidad de Vida , Diálisis Renal/mortalidad , Encuestas y Cuestionarios , Adulto , Anciano , Anciano de 80 o más Años , Algoritmos , Comorbilidad , Enfermedad de la Arteria Coronaria/complicaciones , Enfermedad de la Arteria Coronaria/epidemiología , Estudios Transversales , Femenino , Estudios de Seguimiento , Insuficiencia Cardíaca/complicaciones , Insuficiencia Cardíaca/epidemiología , Humanos , Masculino , Persona de Mediana Edad , Noruega/epidemiología , Diálisis Peritoneal/mortalidad , Modelos de Riesgos Proporcionales , Insuficiencia Renal/etiología , Tasa de Supervivencia/tendencias
2.
Gen Hosp Psychiatry ; 33(5): 454-61, 2011.
Artículo en Inglés | MEDLINE | ID: mdl-21831445

RESUMEN

OBJECTIVE: The objective of the study was to identify the prevalence of depression, anxiety and somatoform disorders in dialysis patients according to dialysis modality and to compare dialysis patients with and without psychiatric comorbidity regarding clinical characteristics, health-related quality of life (HRQoL) and markers of nutrition and inflammation. METHODS: One hundred and nine patients were assessed for depression, anxiety and somatoform disorder with the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. The Short Form 36 was used. Sociodemographic, clinical and laboratory data were collected. RESULTS: About one third, 30.3%, had a current psychiatric disorder regardless of dialysis modality (depression, 22%; anxiety, 17%; somatoform disorders, 1%), and these reported more impairment on HRQoL dimensions. In the multivariate analysis, significant correlations between psychiatric comorbidity and C-reactive protein (CRP≥6 mmol/L) [odds ratio (OR), 3.6; 95% confidence interval (CI), 1.3-9.9; P=.015] and body mass index (BMI≤21 kg/m(2)) (OR, 4.2; 95% CI, 1.4-12.7; P=.011) were observed. CONCLUSION: Depressive and anxiety disorders were common in dialysis patients and were associated with impaired HRQoL, while prevalence of somatoform disorders was low. A strong correlation between psychiatric comorbidity, CRP and BMI indicates that special attention should be given to patients with CRP≥6 mmol/L and BMI≤21 kg/m(2).


Asunto(s)
Desnutrición/epidemiología , Desnutrición/psicología , Trastornos Mentales/epidemiología , Trastornos Mentales/psicología , Diálisis Renal/psicología , Adulto , Anciano , Índice de Masa Corporal , Proteína C-Reactiva/análisis , Comorbilidad , Diálisis , Femenino , Humanos , Modelos Logísticos , Masculino , Desnutrición/complicaciones , Trastornos Mentales/diagnóstico , Persona de Mediana Edad , Noruega/epidemiología , Prevalencia , Escalas de Valoración Psiquiátrica , Calidad de Vida , Factores de Riesgo
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