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1.
Vopr Med Khim ; 36(3): 69-71, 1990.
Artículo en Ruso | MEDLINE | ID: mdl-2143337

RESUMEN

Alterations in activity of membrane-bound Ca2(+)-ATPases were shown to depend on the rate of lipid peroxidation in cell membranes of patients with hypertension during the period of crisis. On the basis from these results antioxidants and Ca2(+)-antagonistic drugs could be used for treatment of hypertensive crisis. Monitoring of the disease is possible by means of estimation of the membrane-bound Ca2(+)-ATPases activity.


Asunto(s)
ATPasas Transportadoras de Calcio/sangre , Membrana Eritrocítica/enzimología , Hipertensión/enzimología , Peroxidación de Lípido , Lípidos de la Membrana/sangre , Adulto , Humanos , Hipertensión/tratamiento farmacológico , Hipertensión/metabolismo , Persona de Mediana Edad , Factores de Tiempo
2.
Klin Med (Mosk) ; 68(12): 20-2, 1990 Dec.
Artículo en Ruso | MEDLINE | ID: mdl-2084329

RESUMEN

++Non-ezymatic lipid peroxidation (LP) and total lipids (TL) in serum and erythrocytic membranes were studied in 42 hypertensive subjects and 35 chronic sufferers with pyelonephritis accompanied by arterial hypertension. The measurements performed at different phases of the clinical course provided evidence in favour of possible application of LP and TL tests in differentiating essential hypertension from chronic pyelonephritis with arterial hypertension.


Asunto(s)
Membrana Eritrocítica/metabolismo , Hipertensión/sangre , Peroxidación de Lípido/fisiología , Lípidos/sangre , Pielonefritis/sangre , Adulto , Enfermedad Crónica , Femenino , Humanos , Hipertensión Renal/sangre , Hipertensión Renal/etiología , Masculino , Persona de Mediana Edad , Pielonefritis/complicaciones
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