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Acta Biomed ; 76(1): 33-6, 2005 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-16116823

RESUMEN

BACKGROUND AND AIM OF THE WORK: Our purpose was to evaluate the efficacy of a single-dose of MTX for ectopic pregnancy treatment in a sample of patients carefully selected according to strict inclusion criteria. METHODS: 11 patients that matched the inclusion criteria were enrolled. RESULTS: Beta-hCG at diagnosis averaged 1349 mIU/ml out of the 11 treated patients, 10 (90%) received a single dose of MTX and had a time of EP resolution averaging 27.3 days. The remaining patient received an additional dose of MTX, equal to the start dose, with a time resolution of 35 days. CONCLUSIONS: This study provides evidence of the efficacy of MTX in EP treatment, both as therapy and as a form of clinical management: the successful medical management of EP, defined as beta-hCG levels becoming negative after administration of one or more MTX doses, was obtained in all treated cases.


Asunto(s)
Abortivos no Esteroideos/administración & dosificación , Metotrexato/administración & dosificación , Embarazo Ectópico/tratamiento farmacológico , Adulto , Gonadotropina Coriónica Humana de Subunidad beta/sangre , Femenino , Humanos , Inyecciones Intramusculares , Embarazo , Embarazo Ectópico/sangre , Factores de Tiempo , Resultado del Tratamiento
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