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1.

Embracing cancer complexity: Hallmarks of systemic disease.

Swanton, Charles; Bernard, Elsa; Abbosh, Chris; André, Fabrice; Auwerx, Johan; Balmain, Allan; Bar-Sagi, Dafna; Bernards, René; Bullman, Susan; DeGregori, James; Elliott, Catherine; Erez, Ayelet; Evan, Gerard; Febbraio, Mark A; Hidalgo, Andrés; Jamal-Hanjani, Mariam; Joyce, Johanna A; Kaiser, Matthew; Lamia, Katja; Locasale, Jason W; Loi, Sherene; Malanchi, Ilaria; Merad, Miriam; Musgrave, Kathryn; Patel, Ketan J; Quezada, Sergio; Wargo, Jennifer A; Weeraratna, Ashani; White, Eileen; Winkler, Frank; Wood, John N; Vousden, Karen H; Hanahan, Douglas.

Cell; 187(7): 1589-1616, 2024 Mar 28.

Artículo en Inglés | MEDLINE | ID: mdl-38552609

2.

Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion.

Gangoso, Ester; Southgate, Benjamin; Bradley, Leanne; Rus, Stefanie; Galvez-Cancino, Felipe; McGivern, Niamh; Güç, Esra; Kapourani, Chantriolnt-Andreas; Byron, Adam; Ferguson, Kirsty M; Alfazema, Neza; Morrison, Gillian; Grant, Vivien; Blin, Carla; Sou, IengFong; Marques-Torrejon, Maria Angeles; Conde, Lucia; Parrinello, Simona; Herrero, Javier; Beck, Stephan; Brandner, Sebastian; Brennan, Paul M; Bertone, Paul; Pollard, Jeffrey W; Quezada, Sergio A; Sproul, Duncan; Frame, Margaret C; Serrels, Alan; Pollard, Steven M.

Cell; 184(9): 2454-2470.e26, 2021 04 29.

Artículo en Inglés | MEDLINE | ID: mdl-33857425

3.

Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition.

Litchfield, Kevin; Reading, James L; Puttick, Clare; Thakkar, Krupa; Abbosh, Chris; Bentham, Robert; Watkins, Thomas B K; Rosenthal, Rachel; Biswas, Dhruva; Rowan, Andrew; Lim, Emilia; Al Bakir, Maise; Turati, Virginia; Guerra-Assunção, José Afonso; Conde, Lucia; Furness, Andrew J S; Saini, Sunil Kumar; Hadrup, Sine R; Herrero, Javier; Lee, Se-Hoon; Van Loo, Peter; Enver, Tariq; Larkin, James; Hellmann, Matthew D; Turajlic, Samra; Quezada, Sergio A; McGranahan, Nicholas; Swanton, Charles.

Cell; 184(3): 596-614.e14, 2021 02 04.

Artículo en Inglés | MEDLINE | ID: mdl-33508232

4.

Cancer cell-intrinsic mechanisms driving acquired immune tolerance.

Ghorani, Ehsan; Swanton, Charles; Quezada, Sergio A.

Immunity; 56(10): 2270-2295, 2023 10 10.

Artículo en Inglés | MEDLINE | ID: mdl-37820584

5.

Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity.

Zelenay, Santiago; van der Veen, Annemarthe G; Böttcher, Jan P; Snelgrove, Kathryn J; Rogers, Neil; Acton, Sophie E; Chakravarty, Probir; Girotti, Maria Romina; Marais, Richard; Quezada, Sergio A; Sahai, Erik; Reis e Sousa, Caetano.

Cell; 162(6): 1257-70, 2015 Sep 10.

Artículo en Inglés | MEDLINE | ID: mdl-26343581

6.

Deciphering immunoregulatory vulnerabilities in human cancers.

Gálvez-Cancino, Felipe; Lladser, Alvaro; Quezada, Sergio A.

Nat Immunol; 23(7): 995-996, 2022 07.

Artículo en Inglés | MEDLINE | ID: mdl-35726061

7.

Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4⁺ T Cells.

Sledzinska, Anna; Vila de Mucha, Maria; Bergerhoff, Katharina; Hotblack, Alastair; Demane, Dafne Franz; Ghorani, Ehsan; Akarca, Ayse U; Marzolini, Maria A V; Solomon, Isabelle; Vargas, Frederick Arce; Pule, Martin; Ono, Masahiro; Seddon, Benedict; Kassiotis, George; Ariyan, Charlotte E; Korn, Thomas; Marafioti, Teresa; Lord, Graham M; Stauss, Hans; Jenner, Richard G; Peggs, Karl S; Quezada, Sergio A.

Immunity; 52(1): 151-166.e6, 2020 01 14.

Artículo en Inglés | MEDLINE | ID: mdl-31924474

8.

Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors.

Arce Vargas, Frederick; Furness, Andrew J S; Solomon, Isabelle; Joshi, Kroopa; Mekkaoui, Leila; Lesko, Marta H; Miranda Rota, Enrique; Dahan, Rony; Georgiou, Andrew; Sledzinska, Anna; Ben Aissa, Assma; Franz, Dafne; Werner Sunderland, Mariana; Wong, Yien Ning Sophia; Henry, Jake Y; O'Brien, Tim; Nicol, David; Challacombe, Ben; Beers, Stephen A; Turajlic, Samra; Gore, Martin; Larkin, James; Swanton, Charles; Chester, Kerry A; Pule, Martin; Ravetch, Jeffrey V; Marafioti, Teresa; Peggs, Karl S; Quezada, Sergio A.

Immunity; 46(4): 577-586, 2017 04 18.

Artículo en Inglés | MEDLINE | ID: mdl-28410988

9.

Too Much of a Good Thing? Chronic IFN Fuels Resistance to Cancer Immunotherapy.

Reading, James L; Quezada, Sergio A.

Immunity; 45(6): 1181-1183, 2016 12 20.

Artículo en Inglés | MEDLINE | ID: mdl-28002724

10.

The Heterogeneity of Ly6C^hi Monocytes Controls Their Differentiation into iNOS⁺ Macrophages or Monocyte-Derived Dendritic Cells.

Menezes, Shinelle; Melandri, Daisy; Anselmi, Giorgio; Perchet, Thibaut; Loschko, Jakob; Dubrot, Juan; Patel, Rajen; Gautier, Emmanuel L; Hugues, Stéphanie; Longhi, M Paula; Henry, Jake Y; Quezada, Sergio A; Lauvau, Grégoire; Lennon-Duménil, Ana-Maria; Gutiérrez-Martínez, Enrique; Bessis, Alain; Gomez-Perdiguero, Elisa; Jacome-Galarza, Christian E; Garner, Hannah; Geissmann, Frederic; Golub, Rachel; Nussenzweig, Michel C; Guermonprez, Pierre.

Immunity; 45(6): 1205-1218, 2016 12 20.

Artículo en Inglés | MEDLINE | ID: mdl-28002729

11.

Neoantigen-directed immune escape in lung cancer evolution.

Rosenthal, Rachel; Cadieux, Elizabeth Larose; Salgado, Roberto; Bakir, Maise Al; Moore, David A; Hiley, Crispin T; Lund, Tom; Tanic, Miljana; Reading, James L; Joshi, Kroopa; Henry, Jake Y; Ghorani, Ehsan; Wilson, Gareth A; Birkbak, Nicolai J; Jamal-Hanjani, Mariam; Veeriah, Selvaraju; Szallasi, Zoltan; Loi, Sherene; Hellmann, Matthew D; Feber, Andrew; Chain, Benny; Herrero, Javier; Quezada, Sergio A; Demeulemeester, Jonas; Van Loo, Peter; Beck, Stephan; McGranahan, Nicholas; Swanton, Charles.

Nature; 567(7749): 479-485, 2019 03.

Artículo en Inglés | MEDLINE | ID: mdl-30894752

12.

The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2.

Hartwig, Torsten; Montinaro, Antonella; von Karstedt, Silvia; Sevko, Alexandra; Surinova, Silvia; Chakravarthy, Ankur; Taraborrelli, Lucia; Draber, Peter; Lafont, Elodie; Arce Vargas, Frederick; El-Bahrawy, Mona A; Quezada, Sergio A; Walczak, Henning.

Mol Cell; 65(4): 730-742.e5, 2017 Feb 16.

Artículo en Inglés | MEDLINE | ID: mdl-28212753

13.

The tumour ecology of quiescence: Niches across scales of complexity.

Castillo, Simon P; Galvez-Cancino, Felipe; Liu, Jiali; Pollard, Steven M; Quezada, Sergio A; Yuan, Yinyin.

Semin Cancer Biol; 92: 139-149, 2023 07.

Artículo en Inglés | MEDLINE | ID: mdl-37037400

14.

PD-L1 signaling on human memory CD4+ T cells induces a regulatory phenotype.

Fanelli, Giorgia; Romano, Marco; Nova-Lamperti, Estefania; Werner Sunderland, Mariana; Nerviani, Alessandra; Scottà, Cristiano; Bombardieri, Michele; Quezada, Sergio A; Sacks, Steven H; Noelle, Randolph J; Pitzalis, Costantino; Lechler, Robert I; Lombardi, Giovanna; Becker, Pablo D.

PLoS Biol; 19(4): e3001199, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-33901179

15.

Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd - 4th, 2021, Italy).

Ascierto, Paolo A; Agarwala, Sanjiv S; Blank, Christian; Caracò, Corrado; Carvajal, Richard D; Ernstoff, Marc S; Ferrone, Soldano; Fox, Bernard A; Gajewski, Thomas F; Garbe, Claus; Grob, Jean-Jacques; Hamid, Omid; Krogsgaard, Michelle; Lo, Roger S; Lund, Amanda W; Madonna, Gabriele; Michielin, Olivier; Neyns, Bart; Osman, Iman; Peters, Solange; Poulikakos, Poulikos I; Quezada, Sergio A; Reinfeld, Bradley; Zitvogel, Laurence; Puzanov, Igor; Thurin, Magdalena.

J Transl Med; 20(1): 391, 2022 09 04.

Artículo en Inglés | MEDLINE | ID: mdl-36058945

16.

High inter-follicular spatial co-localization of CD8+FOXP3+ with CD4+CD8+ cells predicts favorable outcome in follicular lymphoma.

Hagos, Yeman B; Akarca, Ayse U; Ramsay, Alan; Rossi, Riccardo L; Pomplun, Sabine; Ngai, Victoria; Moioli, Alessia; Gianatti, Andrea; Mcnamara, Christopher; Rambaldi, Alessandro; Quezada, Sergio A; Linch, David; Gritti, Giuseppe; Yuan, Yinyin; Marafioti, Teresa.

Hematol Oncol; 40(4): 541-553, 2022 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-35451108

17.

The function and dysfunction of memory CD8⁺ T cells in tumor immunity.

Reading, James L; Gálvez-Cancino, Felipe; Swanton, Charles; Lladser, Alvaro; Peggs, Karl S; Quezada, Sergio A.

Immunol Rev; 283(1): 194-212, 2018 05.

Artículo en Inglés | MEDLINE | ID: mdl-29664561

18.

Potential of Magnetic Hyperthermia to Stimulate Localized Immune Activation.

Carter, Thomas J; Agliardi, Giulia; Lin, Fang-Yu; Ellis, Matthew; Jones, Clare; Robson, Mathew; Richard-Londt, Angela; Southern, Paul; Lythgoe, Mark; Zaw Thin, May; Ryzhov, Vyacheslav; de Rosales, Rafael T M; Gruettner, Cordula; Abdollah, Maha R A; Pedley, R Barbara; Pankhurst, Quentin A; Kalber, Tammy L; Brandner, Sebastian; Quezada, Sergio; Mulholland, Paul; Shevtsov, Maxim; Chester, Kerry.

Small; 17(14): e2005241, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-33734595

19.

Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 3rd-5th, 2020, Italy).

Ascierto, Paolo A; Blank, Christian; Dummer, Reinhard; Ernstoff, Marc S; Ferrone, Soldano; Fox, Bernard A; Gajewski, Thomas F; Garbe, Claus; Hwu, Patrick; Kalinski, Pawel; Krogsgaard, Michelle; Lo, Roger S; Luke, Jason J; Neyns, Bart; Postow, Michael A; Quezada, Sergio A; Teng, Michele W L; Trinchieri, Giorgio; Testori, Alessandro; Caracò, Corrado; Osman, Iman; Puzanov, Igor; Thurin, Magdalena.

J Transl Med; 19(1): 278, 2021 06 30.

Artículo en Inglés | MEDLINE | ID: mdl-34193182

20.

An antitumor boost to TH9 cells.

Quezada, Sergio A; Peggs, Karl S.

Nat Immunol; 15(8): 703-5, 2014 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-25045872

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