Assessing the Skin and UV Neoplasia Transplant Risk Assessment Calculator in an Irish cohort of thoracic organ transplant recipients.

The Skin and UV Neoplasia Transplant Risk Assessment Calculator (SUNTRAC) is a tool that can be used to decide when to first screen for skin cancer in organ transplant recipients (OTRs). The objective of this study was to assess the applicability of this tool in thoracic OTRs. Based on data from patient files, the OTRs were categorized into four risk groups according to the SUNTRAC tool. The time of the first post-transplant skin cancer in each OTR was recorded. The proportion of OTRs with post-transplant skin cancer in the low-, medium-, high- and very high-risk groups was 0%, 28.3%, 58.3% and 100%, respectively. This positive correlation suggests that SUNTRAC can be used to determine when to first screen for skin cancer in heart and lung OTRs.

Network-wide safety impacts of dedicated lanes for connected and autonomous vehicles.

Cooperative, Connected and Automated Mobility (CCAM) enabled by Connected and Autonomous Vehicles (CAVs) has potential to change future transport systems. The findings from previous studies suggest that these technologies will improve traffic flow, reduce travel time and delays. Furthermore, these CAVs will be safer compared to existing vehicles. As these vehicles may have the ability to travel at a higher speed and with shorter headways, it has been argued that infrastructure-based measures are required to optimise traffic flow and road user comfort. One of these measures is the use of a dedicated lane for CAVs on urban highways and arterials and constitutes the focus of this research. As the potential impact on safety is unclear, the present study aims to evaluate the safety impacts of dedicated lanes for CAVs. A calibrated and validated microsimulation model developed in AIMSUN was used to simulate and produce safety results. These results were analysed with the help of the Surrogate Safety Assessment Model (SSAM). The model includes human-driven vehicles (HDVs), 1st generation and 2nd generation autonomous vehicles (AVs) with different sets of parameters leading to different movement behaviour. The model uses a variety of cases in which a dedicated lane is provided at different type of lanes (inner and outer) of highways to understand the safety effects. The model also tries to understand the minimum required market penetration rate (MPR) of CAVs for a better movement of traffic on dedicated lanes. It was observed in the models that although at low penetration rates of CAVs (around 20%) dedicated lanes might not be advantageous, a reduction of 53% to 58% in traffic conflicts is achieved with the introduction of dedicated lanes in high CAV MPRs. In addition, traffic crashes estimated from traffic conflicts are reduced up to 48% with the CAVs. The simulation results revealed that with dedicated lane, the combination of 40-40-20 (i.e., 40% human-driven - 40% 1st generation AVs- 20% 2nd generation AVs) could be the optimum MPR for CAVs to achieve the best safety benefits. The findings in this study provide useful insight into the safety impacts of dedicated lanes for CAVs and could be used to develop a policy support tool for local authorities and practitioners.

Review and ranking of crash risk factors related to the road infrastructure.

The objective of this paper is the review and comparative assessment of infrastructure related crash risk factors, with the explicit purpose of ranking them based on how detrimental they are towards road safety (i.e. crash risk, frequency and severity). This analysis was carried out within the SafetyCube project, which aimed to identify and quantify the effects of risk factors and measures related to behaviour, infrastructure or vehicles, and integrate the results in an innovative road safety Decision Support System (DSS). The evaluation was conducted by examining studies from the existing literature. These were selected and analysed using a specifically designed common methodology. Infrastructure risk factors were structured in a hierarchical taxonomy of 10 areas with several risk factors in each area (59 specific risk factors in total), examples include: alignment features (e.g. horizontal-vertical alignment deficiencies), cross-section characteristics (e.g. superelevation, lanes, median and shoulder deficiencies), road surface deficiencies, workzones, junction deficiencies (interchange and at-grade) etc. Consultation with infrastructure stakeholders (international organisations, road authorities, etc.) took place in dedicated workshops to identify user needs for the DSS, as well as "hot topics" of particular importance. The following analysis methodology was applied to each infrastructure risk factor: (i) A search for relevant international literature, (ii) Selection of studies on the basis of rigorous criteria, (iii) Analysis of studies in terms of design, methods and limitations, (iv) Synthesis of findings - and meta-analysis, when feasible. In total 243 recent and high quality studies were selected and analysed. Synthesis of results was made through 39 'Synopses' (including 4 original meta-analyses) on individual risk factors or groups of risk factors. This allowed the ranking of infrastructure risk factors into three groups: risky (11 risk factors), probably risky (18 risk factors), and unclear (7 risk factors).