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1.

Immunology of human fibrosis.

Bhattacharya, Mallar; Ramachandran, Prakash.

Nat Immunol; 24(9): 1423-1433, 2023 09.

Artículo en Inglés | MEDLINE | ID: mdl-37474654

2.

Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling.

Kotsiliti, Elena; Leone, Valentina; Schuehle, Svenja; Govaere, Olivier; Li, Hai; Wolf, Monika J; Horvatic, Helena; Bierwirth, Sandra; Hundertmark, Jana; Inverso, Donato; Zizmare, Laimdota; Sarusi-Portuguez, Avital; Gupta, Revant; O'Connor, Tracy; Giannou, Anastasios D; Shiri, Ahmad Mustafa; Schlesinger, Yehuda; Beccaria, Maria Garcia; Rennert, Charlotte; Pfister, Dominik; Öllinger, Rupert; Gadjalova, Iana; Ramadori, Pierluigi; Rahbari, Mohammad; Rahbari, Nuh; Healy, Marc E; Fernández-Vaquero, Mirian; Yahoo, Neda; Janzen, Jakob; Singh, Indrabahadur; Fan, Chaofan; Liu, Xinyuan; Rau, Monika; Feuchtenberger, Martin; Schwaneck, Eva; Wallace, Sebastian J; Cockell, Simon; Wilson-Kanamori, John; Ramachandran, Prakash; Kho, Celia; Kendall, Timothy J; Leblond, Anne-Laure; Keppler, Selina J; Bielecki, Piotr; Steiger, Katja; Hofmann, Maike; Rippe, Karsten; Zitzelsberger, Horst; Weber, Achim; Malek, Nisar.

J Hepatol; 79(2): 296-313, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37224925

3.

Genome-wide analysis identifies gallstone-susceptibility loci including genes regulating gastrointestinal motility.

Fairfield, Cameron J; Drake, Thomas M; Pius, Riinu; Bretherick, Andrew D; Campbell, Archie; Clark, David W; Fallowfield, Jonathan A; Hayward, Caroline; Henderson, Neil C; Iakovliev, Andrii; Joshi, Peter K; Mills, Nicholas L; Porteous, David J; Ramachandran, Prakash; Semple, Robert K; Shaw, Catherine A; Sudlow, Cathie L W; Timmers, Paul R H J; Wilson, James F; Wigmore, Stephen J; Spiliopoulou, Athina; Harrison, Ewen M.

Hepatology; 75(5): 1081-1094, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-34651315

4.

Single-cell analyses and machine learning define hematopoietic progenitor and HSC-like cells derived from human PSCs.

Fidanza, Antonella; Stumpf, Patrick S; Ramachandran, Prakash; Tamagno, Sara; Babtie, Ann; Lopez-Yrigoyen, Martha; Taylor, A Helen; Easterbrook, Jennifer; Henderson, Beth E P; Axton, Richard; Henderson, Neil C; Medvinsky, Alexander; Ottersbach, Katrin; Romanò, Nicola; Forrester, Lesley M.

Blood; 136(25): 2893-2904, 2020 12 17.

Artículo en Inglés | MEDLINE | ID: mdl-32614947

5.

Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease.

Conway, Bryan R; O'Sullivan, Eoin D; Cairns, Carolynn; O'Sullivan, James; Simpson, Daniel J; Salzano, Angela; Connor, Katie; Ding, Peng; Humphries, Duncan; Stewart, Kevin; Teenan, Oliver; Pius, Riinu; Henderson, Neil C; Bénézech, Cécile; Ramachandran, Prakash; Ferenbach, David; Hughes, Jeremy; Chandra, Tamir; Denby, Laura.

J Am Soc Nephrol; 31(12): 2833-2854, 2020 12.

Artículo en Inglés | MEDLINE | ID: mdl-32978267

6.

Adipose tissue macrophage dysfunction in human MASLD - Cause or consequence?

Colella, Fabio; Ramachandran, Prakash.

J Hepatol; 80(3): 390-393, 2024 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-38122832

7.

11Beta-hydroxysteroid dehydrogenase-1 deficiency or inhibition enhances hepatic myofibroblast activation in murine liver fibrosis.

Zou, Xiantong; Ramachandran, Prakash; Kendall, Timothy J; Pellicoro, Antonella; Dora, Elena; Aucott, Rebecca L; Manwani, Kajal; Man, Tak Yung; Chapman, Karen E; Henderson, Neil C; Forbes, Stuart J; Webster, Scott P; Iredale, John P; Walker, Brian R; Michailidou, Zoi.

Hepatology; 67(6): 2167-2181, 2018 06.

Artículo en Inglés | MEDLINE | ID: mdl-29251794

8.

Sphingosine-1-Phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis.

King, Andrew; Houlihan, Diarmaid D; Kavanagh, Dean; Haldar, Debashis; Luu, Nguyet; Owen, Andrew; Suresh, Shankar; Than, Nwe Ni; Reynolds, Gary; Penny, Jasmine; Sumption, Henry; Ramachandran, Prakash; Henderson, Neil C; Kalia, Neena; Frampton, Jon; Adams, David H; Newsome, Philip N.

Gastroenterology; 153(1): 233-248.e16, 2017 07.

Artículo en Inglés | MEDLINE | ID: mdl-28363640

9.

Serelaxin as a potential treatment for renal dysfunction in cirrhosis: Preclinical evaluation and results of a randomized phase 2 trial.

Snowdon, Victoria K; Lachlan, Neil J; Hoy, Anna M; Hadoke, Patrick W F; Semple, Scott I; Patel, Dilip; Mungall, Will; Kendall, Timothy J; Thomson, Adrian; Lennen, Ross J; Jansen, Maurits A; Moran, Carmel M; Pellicoro, Antonella; Ramachandran, Prakash; Shaw, Isaac; Aucott, Rebecca L; Severin, Thomas; Saini, Rajnish; Pak, Judy; Yates, Denise; Dongre, Neelesh; Duffield, Jeremy S; Webb, David J; Iredale, John P; Hayes, Peter C; Fallowfield, Jonathan A.

PLoS Med; 14(2): e1002248, 2017 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-28245243

10.

Resolution of liver fibrosis: basic mechanisms and clinical relevance.

Ramachandran, Prakash; Iredale, John P; Fallowfield, Jonathan A.

Semin Liver Dis; 35(2): 119-31, 2015 May.

Artículo en Inglés | MEDLINE | ID: mdl-25974898

11.

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis.

Ramachandran, Prakash; Pellicoro, Antonella; Vernon, Madeleine A; Boulter, Luke; Aucott, Rebecca L; Ali, Aysha; Hartland, Stephen N; Snowdon, Victoria K; Cappon, Andrea; Gordon-Walker, Timothy T; Williams, Mike J; Dunbar, Donald R; Manning, Jonathan R; van Rooijen, Nico; Fallowfield, Jonathan A; Forbes, Stuart J; Iredale, John P.

Proc Natl Acad Sci U S A; 109(46): E3186-95, 2012 Nov 13.

Artículo en Inglés | MEDLINE | ID: mdl-23100531

12.

Phenotypic and spatial heterogeneity of brain myeloid cells after stroke is associated with cell ontogeny, tissue damage, and brain connectivity.

Patir, Anirudh; Barrington, Jack; Szymkowiak, Stefan; Brezzo, Gaia; Straus, Dana; Alfieri, Alessio; Lefevre, Lucas; Liu, Zhaoyuan; Ginhoux, Florent; Henderson, Neil C; Horsburgh, Karen; Ramachandran, Prakash; McColl, Barry W.

Cell Rep; 43(5): 114250, 2024 May 17.

Artículo en Inglés | MEDLINE | ID: mdl-38762882

13.

Studies of macrophage therapy for cirrhosis - From mice to men.

Thomas, James A; Ramachandran, Prakash; Forbes, Stuart J.

J Hepatol; 68(5): 1090-1091, 2018 05.

Artículo en Inglés | MEDLINE | ID: mdl-29317297

14.

Elastin accumulation is regulated at the level of degradation by macrophage metalloelastase (MMP-12) during experimental liver fibrosis.

Pellicoro, Antonella; Aucott, Rebecca L; Ramachandran, Prakash; Robson, Andrew J; Fallowfield, Jonathan A; Snowdon, Victoria K; Hartland, Stephen N; Vernon, Madeleine; Duffield, Jeremy S; Benyon, R Christopher; Forbes, Stuart J; Iredale, John P.

Hepatology; 55(6): 1965-75, 2012 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-22223197

15.

An integrated gene-to-outcome multimodal database for metabolic dysfunction-associated steatotic liver disease.

Kendall, Timothy J; Jimenez-Ramos, Maria; Turner, Frances; Ramachandran, Prakash; Minnier, Jessica; McColgan, Michael D; Alam, Masood; Ellis, Harriet; Dunbar, Donald R; Kohnen, Gabriele; Konanahalli, Prakash; Oien, Karin A; Bandiera, Lucia; Menolascina, Filippo; Juncker-Jensen, Anna; Alexander, Douglas; Mayor, Charlie; Guha, Indra Neil; Fallowfield, Jonathan A.

Nat Med; 29(11): 2939-2953, 2023 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-37903863

16.

Macrophages promote anti-androgen resistance in prostate cancer bone disease.

Li, Xue-Feng; Selli, Cigdem; Zhou, Han-Lin; Cao, Jian; Wu, Shuiqing; Ma, Ruo-Yu; Lu, Ye; Zhang, Cheng-Bin; Xun, Bijie; Lam, Alyson D; Pang, Xiao-Cong; Fernando, Anu; Zhang, Zeda; Unciti-Broceta, Asier; Carragher, Neil O; Ramachandran, Prakash; Henderson, Neil C; Sun, Ling-Ling; Hu, Hai-Yan; Li, Gui-Bo; Sawyers, Charles; Qian, Bin-Zhi.

J Exp Med; 220(4)2023 04 03.

Artículo en Inglés | MEDLINE | ID: mdl-36749798

17.

Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function.

Thomas, James A; Pope, Caroline; Wojtacha, Davina; Robson, Andrew J; Gordon-Walker, Timothy T; Hartland, Stephen; Ramachandran, Prakash; Van Deemter, Marielle; Hume, David A; Iredale, John P; Forbes, Stuart J.

Hepatology; 53(6): 2003-15, 2011 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-21433043

18.

Ly6Chi monocytes direct alternatively activated profibrotic macrophage regulation of lung fibrosis.

Gibbons, Michael A; MacKinnon, Alison C; Ramachandran, Prakash; Dhaliwal, Kevin; Duffin, Rodger; Phythian-Adams, Alexander T; van Rooijen, Nico; Haslett, Christopher; Howie, Sarah E; Simpson, A John; Hirani, Nikhil; Gauldie, Jack; Iredale, John P; Sethi, Tariq; Forbes, Stuart J.

Am J Respir Crit Care Med; 184(5): 569-81, 2011 Sep 01.

Artículo en Inglés | MEDLINE | ID: mdl-21680953

19.

Macrophages as key regulators of liver health and disease.

Papachristoforou, Eleni; Ramachandran, Prakash.

Int Rev Cell Mol Biol; 368: 143-212, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-35636927

20.

Deciphering Mesenchymal Drivers of Human Dupuytren's Disease at Single-Cell Level.

Dobie, Ross; West, Chris C; Henderson, Beth E P; Wilson-Kanamori, John R; Markose, Dyana; Kitto, Laura J; Portman, Jordan R; Beltran, Mariana; Sohrabi, Sadaf; Akram, Ahsan R; Ramachandran, Prakash; Yong, Li Yenn; Davidson, Dominique; Henderson, Neil C.

J Invest Dermatol; 142(1): 114-123.e8, 2022 01.

Artículo en Inglés | MEDLINE | ID: mdl-34274346

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