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1.

Comparison of two targeted ultra-deep sequencing technologies for analysis of plasma circulating tumour DNA in endocrine-therapy-resistant breast cancer patients.

Nteliopoulos, Georgios; Page, Karen; Hills, Allison; Howarth, Karen; Emmett, Warren; Green, Emma; Martinson, Luke J; Fernadez-Garcia, Daniel; Hastings, Robert; Guttery, David S; Kenny, Laura; Stebbing, Justin; Cleator, Susan; Rehman, Farah; Gleason, Kelly L T; Sanela, Andrijac; Ion, Charlotte; Rushton, Amelia J; Rosenfeld, Nitzan; Coombes, R Charles; Shaw, Jacqueline A.

Breast Cancer Res Treat; 188(2): 465-476, 2021 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-34097174

2.

Palbociclib and endocrine therapy in heavily pretreated hormone receptor-positive HER2-negative advanced breast cancer: the UK Compassionate Access Programme experience.

Battisti, Nicolò Matteo Luca; Kingston, Belinda; King, Judy; Denton, Arshi; Waters, Simon; Sita-Lumsden, Ailsa; Rehman, Farah; Stavraka, Chara; Kristeleit, Hartmut; Sawyer, Elinor; Houghton, David; Davidson, Neville; Howell, Sacha; Choy, Julia; Harper, Peter; Roylance, Rebecca; Fharat, Raja; Mohammed, Kabir; Ring, Alistair; Johnston, Stephen.

Breast Cancer Res Treat; 174(3): 731-740, 2019 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-30656459

3.

Long-term Multimodal Recording Reveals Epigenetic Adaptation Routes in Dormant Breast Cancer Cells.

Rosano, Dalia; Sofyali, Emre; Dhiman, Heena; Ghirardi, Chiara; Ivanoiu, Diana; Heide, Timon; Vingiani, Andrea; Bertolotti, Alessia; Pruneri, Giancarlo; Canale, Eleonora; Dewhurst, Hannah F; Saha, Debjani; Slaven, Neil; Barozzi, Iros; Li, Tong; Zemlyanskiy, Grigory; Phillips, Henry; James, Chela; Gyorffy, Balázs; Lynn, Claire; Cresswell, George D; Rehman, Farah; Noberini, Roberta; Bonaldi, Tiziana; Sottoriva, Andrea; Magnani, Luca.

Cancer Discov; 14(5): 866-889, 2024 May 01.

Artículo en Inglés | MEDLINE | ID: mdl-38527495

4.

Serial Postoperative Circulating Tumor DNA Assessment Has Strong Prognostic Value During Long-Term Follow-Up in Patients With Breast Cancer.

Shaw, Jacqueline A; Page, Karen; Wren, Evie; de Bruin, Elza C; Kalashnikova, Ekaterina; Hastings, Robert; McEwen, Rob; Zhang, Eddie; Wadsley, Marc; Acheampong, Emmanuel; Renner, Derek; Gleason, Kelly L T; Ambasager, Bana; Stetson, Daniel; Fernandez-Garcia, Daniel; Guttery, David; Allsopp, Rebecca C; Rodriguez, Angel; Zimmermann, Bernhard; Sethi, Himanshu; Aleshin, Alexey; Liu, Minetta C; Richards, Cathy; Stebbing, Justin; Ali, Simak; Rehman, Farah; Cleator, Susan; Kenny, Laura; Ahmed, Samreen; Armstrong, Anne C; Coombes, R Charles.

JCO Precis Oncol; 8: e2300456, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38691816

5.

Development of the HT&Me intervention to support women with breast cancer to adhere to adjuvant endocrine therapy and improve quality of life.

Stewart, Sarah-Jane F; Slodkowska-Barabasz, Joanna; McGeagh, Lucy; Moon, Zoe; Brett, Jo; Wells, Mary; Brown, Morven C; Turner, Mark; Horne, Robert; Fenlon, Deborah; Rehman, Farah; Cain, Henry; Donnelly, Peter; Harmer, Victoria; Turner, Lesley; Rose, Jan; Sharp, Linda; Watson, Eila.

Breast; 70: 32-40, 2023 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-37300986

6.

Personalized Detection of Circulating Tumor DNA Antedates Breast Cancer Metastatic Recurrence.

Coombes, Raoul Charles; Page, Karen; Salari, Raheleh; Hastings, Robert K; Armstrong, Anne; Ahmed, Samreen; Ali, Simak; Cleator, Susan; Kenny, Laura; Stebbing, Justin; Rutherford, Mark; Sethi, Himanshu; Boydell, Anna; Swenerton, Ryan; Fernandez-Garcia, Daniel; Gleason, Kelly L T; Goddard, Katie; Guttery, David S; Assaf, Zoe J; Wu, Hsin-Ta; Natarajan, Prashanthi; Moore, David A; Primrose, Lindsay; Dashner, Scott; Tin, Antony S; Balcioglu, Mustafa; Srinivasan, Ramya; Shchegrova, Svetlana V; Olson, Alexander; Hafez, Dina; Billings, Paul; Aleshin, Alexey; Rehman, Farah; Toghill, Bradley J; Hills, Allison; Louie, Maggie C; Lin, Cheng-Ho Jimmy; Zimmermann, Bernhard G; Shaw, Jaqueline A.

Clin Cancer Res; 25(14): 4255-4263, 2019 07 15.

Artículo en Inglés | MEDLINE | ID: mdl-30992300

7.

Genome-wide barcoded transposon screen for cancer drug sensitivity in haploid mouse embryonic stem cells.

Pettitt, Stephen J; Krastev, Dragomir B; Pemberton, Helen N; Fontebasso, Yari; Frankum, Jessica; Rehman, Farah L; Brough, Rachel; Song, Feifei; Bajrami, Ilirjana; Rafiq, Rumana; Wallberg, Fredrik; Kozarewa, Iwanka; Fenwick, Kerry; Armisen-Garrido, Javier; Swain, Amanda; Gulati, Aditi; Campbell, James; Ashworth, Alan; Lord, Christopher J.

Sci Data; 4: 170020, 2017 03 01.

Artículo en Inglés | MEDLINE | ID: mdl-28248920

8.

Aromatase inhibition by 15-deoxy-prostaglandin J(2) (15-dPGJ(2)) and N-(4-hydroxyphenyl)-retinamide (4HPR) is associated with enhanced ceramide production.

Andrews, William J; Winnett, Georgia; Rehman, Farah; Shanmugasundaram, Pradeep; Hagen, Daphne van; Schrey, Michael P.

J Steroid Biochem Mol Biol; 94(1-3): 159-65, 2005 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-15862961

9.

Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity.

Bajrami, Ilirjana; Frankum, Jessica R; Konde, Asha; Miller, Rowan E; Rehman, Farah L; Brough, Rachel; Campbell, James; Sims, David; Rafiq, Rumana; Hooper, Sean; Chen, Lina; Kozarewa, Iwanka; Assiotis, Ioannis; Fenwick, Kerry; Natrajan, Rachael; Lord, Christopher J; Ashworth, Alan.

Cancer Res; 74(1): 287-97, 2014 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-24240700

10.

BMN 673, a novel and highly potent PARP1/2 inhibitor for the treatment of human cancers with DNA repair deficiency.

Shen, Yuqiao; Rehman, Farah L; Feng, Ying; Boshuizen, Julia; Bajrami, Ilirjana; Elliott, Richard; Wang, Bing; Lord, Christopher J; Post, Leonard E; Ashworth, Alan.

Clin Cancer Res; 19(18): 5003-15, 2013 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-23881923

11.

A genetic screen using the PiggyBac transposon in haploid cells identifies Parp1 as a mediator of olaparib toxicity.

Pettitt, Stephen J; Rehman, Farah L; Bajrami, Ilirjana; Brough, Rachel; Wallberg, Fredrik; Kozarewa, Iwanka; Fenwick, Kerry; Assiotis, Ioannis; Chen, Lina; Campbell, James; Lord, Christopher J; Ashworth, Alan.

PLoS One; 8(4): e61520, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-23634208

12.

The promise of combining inhibition of PI3K and PARP as cancer therapy.

Rehman, Farah L; Lord, Christopher J; Ashworth, Alan.

Cancer Discov; 2(11): 982-4, 2012 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-23148373

13.

Sequence based analysis of U-2973, a cell line established from a double-hit B-cell lymphoma with concurrent MYC and BCL2 rearrangements.

Hooper, Sean D; Jiao, Xiang; Sundström, Elisabeth; Rehman, Farah L; Tellgren-Roth, Christian; Sjöblom, Tobias; Cavelier, Lucia.

BMC Res Notes; 5: 648, 2012 Nov 22.

Artículo en Inglés | MEDLINE | ID: mdl-23171647

14.

Synthetic lethal approaches to breast cancer therapy.

Rehman, Farah L; Lord, Christopher J; Ashworth, Alan.

Nat Rev Clin Oncol; 7(12): 718-24, 2010 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-20956981

15.

ASA404: update on drug development.

Rehman, Farah; Rustin, Gordon.

Expert Opin Investig Drugs; 17(10): 1547-51, 2008 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-18808313

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