RESUMEN
This retrospective study aimed at evaluating the recurrence rates of keratocystic odontogenic tumors (KCOTs) that were enucleated with and without the application of Carnoy's solution (CS). The study included 36 KCOTs treated between 1996 and 2006. Recurrence rates were investigated in correlation with the respective treatment method applied. Additionally, any damage to the inferior alveolar nerve associated with treatment was analyzed. Treatments consisted of enucleation with (38.9%) or without (61.1%) the application of CS. Median follow-up was 4.5 years. Single enucleation showed a recurrence rate of 50%, but the additional application of CS reduced the recurrence rate to 14.3%. No detrimental effects of CS on the mandibular nerve were detected. Enucleation plus the application of CS reduced the recurrence rate of KCOTs compared with simple enucleation. The application of CS did not cause any damage to the mandibular nerve.
Asunto(s)
Ácido Acético/uso terapéutico , Antineoplásicos/uso terapéutico , Quimioterapia Adyuvante/métodos , Cloroformo/uso terapéutico , Etanol/uso terapéutico , Neoplasias Maxilomandibulares/tratamiento farmacológico , Recurrencia Local de Neoplasia/prevención & control , Tumores Odontogénicos/tratamiento farmacológico , Ácido Acético/farmacología , Adolescente , Adulto , Anciano , Antineoplásicos/farmacología , Cauterización/métodos , Niño , Cloroformo/farmacología , Supervivencia sin Enfermedad , Etanol/farmacología , Femenino , Humanos , Neoplasias Maxilomandibulares/cirugía , Estimación de Kaplan-Meier , Masculino , Nervio Mandibular/efectos de los fármacos , Persona de Mediana Edad , Neovascularización Patológica/tratamiento farmacológico , Tumores Odontogénicos/cirugía , Estudios Retrospectivos , Adulto JovenRESUMEN
Strongly confined photonic modes can couple to quantum emitters and mechanical excitations. To harness the full potential in quantum photonic circuits, interactions between different constituents have to be precisely and dynamically controlled. Here, a prototypical coupled element, a photonic molecule defined in a photonic crystal membrane, is controlled by a radio frequency surface acoustic wave. The sound wave is tailored to deliberately switch on and off the bond of the photonic molecule on sub-nanosecond timescales. In time-resolved experiments, the acousto-optically controllable coupling is directly observed as clear anticrossings between the two nanophotonic modes. The coupling strength is determined directly from the experimental data. Both the time dependence of the tuning and the inter-cavity coupling strength are found to be in excellent agreement with numerical calculations. The demonstrated mechanical technique can be directly applied for dynamic quantum gate operations in state-of-the-art-coupled nanophotonic, quantum cavity electrodynamic and optomechanical systems.