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1.

Cell survival and protein secretion associated with Golgi integrity in response to Golgi stress-inducing agents.

Ignashkova, Tatiana I; Gendarme, Mathieu; Peschk, Katrin; Eggenweiler, Hans-Michael; Lindemann, Ralph K; Reiling, Jan H.

Traffic; 18(8): 530-544, 2017 08.

Artículo en Inglés | MEDLINE | ID: mdl-28485883

2.

TRAPPC13 modulates autophagy and the response to Golgi stress.

Ramírez-Peinado, Silvia; Ignashkova, Tatiana I; van Raam, Bram J; Baumann, Jan; Sennott, Erica L; Gendarme, Mathieu; Lindemann, Ralph K; Starnbach, Michael N; Reiling, Jan H.

J Cell Sci; 130(14): 2251-2265, 2017 Jul 15.

Artículo en Inglés | MEDLINE | ID: mdl-28536105

3.

Increased mTORC1 signaling UPRegulates stress.

Reiling, Jan H; Sabatini, David M.

Mol Cell; 29(5): 533-5, 2008 Mar 14.

Artículo en Inglés | MEDLINE | ID: mdl-18342598

4.

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.

Barbie, David A; Tamayo, Pablo; Boehm, Jesse S; Kim, So Young; Moody, Susan E; Dunn, Ian F; Schinzel, Anna C; Sandy, Peter; Meylan, Etienne; Scholl, Claudia; Fröhling, Stefan; Chan, Edmond M; Sos, Martin L; Michel, Kathrin; Mermel, Craig; Silver, Serena J; Weir, Barbara A; Reiling, Jan H; Sheng, Qing; Gupta, Piyush B; Wadlow, Raymond C; Le, Hanh; Hoersch, Sebastian; Wittner, Ben S; Ramaswamy, Sridhar; Livingston, David M; Sabatini, David M; Meyerson, Matthew; Thomas, Roman K; Lander, Eric S; Mesirov, Jill P; Root, David E; Gilliland, D Gary; Jacks, Tyler; Hahn, William C.

Nature; 462(7269): 108-12, 2009 Nov 05.

Artículo en Inglés | MEDLINE | ID: mdl-19847166

5.

A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin.

Reiling, Jan H; Clish, Clary B; Carette, Jan E; Varadarajan, Malini; Brummelkamp, Thijn R; Sabatini, David M.

Proc Natl Acad Sci U S A; 108(29): 11756-65, 2011 Jul 19.

Artículo en Inglés | MEDLINE | ID: mdl-21677192

6.

MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.

Alborzinia, Hamed; Flórez, Andrés F; Kreth, Sina; Brückner, Lena M; Yildiz, Umut; Gartlgruber, Moritz; Odoni, Dorett I; Poschet, Gernot; Garbowicz, Karolina; Shao, Chunxuan; Klein, Corinna; Meier, Jasmin; Zeisberger, Petra; Nadler-Holly, Michal; Ziehm, Matthias; Paul, Franziska; Burhenne, Jürgen; Bell, Emma; Shaikhkarami, Marjan; Würth, Roberto; Stainczyk, Sabine A; Wecht, Elisa M; Kreth, Jochen; Büttner, Michael; Ishaque, Naveed; Schlesner, Matthias; Nicke, Barbara; Stresemann, Carlo; Llamazares-Prada, María; Reiling, Jan H; Fischer, Matthias; Amit, Ido; Selbach, Matthias; Herrmann, Carl; Wölfl, Stefan; Henrich, Kai-Oliver; Höfer, Thomas; Trumpp, Andreas; Westermann, Frank.

Nat Cancer; 3(4): 471-485, 2022 04.

Artículo en Inglés | MEDLINE | ID: mdl-35484422

7.

Off-target effects associated with long dsRNAs in Drosophila RNAi screens.

Moffat, Jason; Reiling, Jan H; Sabatini, David M.

Trends Pharmacol Sci; 28(4): 149-51, 2007 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-17350110

8.

Diet-dependent effects of the Drosophila Mnk1/Mnk2 homolog Lk6 on growth via eIF4E.

Reiling, Jan H; Doepfner, Kathrin T; Hafen, Ernst; Stocker, Hugo.

Curr Biol; 15(1): 24-30, 2005 Jan 11.

Artículo en Inglés | MEDLINE | ID: mdl-15649360

9.

Golgi stress mediates redox imbalance and ferroptosis in human cells.

Alborzinia, Hamed; Ignashkova, Tatiana I; Dejure, Francesca R; Gendarme, Mathieu; Theobald, Jannick; Wölfl, Stefan; Lindemann, Ralph K; Reiling, Jan H.

Commun Biol; 1: 210, 2018.

Artículo en Inglés | MEDLINE | ID: mdl-30511023

10.

Golgi stress-induced transcriptional changes mediated by MAPK signaling and three ETS transcription factors regulate MCL1 splicing.

Baumann, Jan; Ignashkova, Tatiana I; Chirasani, Sridhar R; Ramírez-Peinado, Silvia; Alborzinia, Hamed; Gendarme, Mathieu; Kuhnigk, Kyra; Kramer, Valentin; Lindemann, Ralph K; Reiling, Jan H.

Mol Biol Cell; 29(1): 42-52, 2018 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-29118074

11.

Secretory stressors induce intracellular death receptor accumulation to control apoptosis.

van Raam, Bram J; Lacina, Tamara; Lindemann, Ralph K; Reiling, Jan H.

Cell Death Dis; 8(10): e3069, 2017 10 05.

Artículo en Inglés | MEDLINE | ID: mdl-28981087

12.

Image-based drug screen identifies HDAC inhibitors as novel Golgi disruptors synergizing with JQ1.

Gendarme, Mathieu; Baumann, Jan; Ignashkova, Tatiana I; Lindemann, Ralph K; Reiling, Jan H.

Mol Biol Cell; 28(26): 3756-3772, 2017 Dec 15.

Artículo en Inglés | MEDLINE | ID: mdl-29074567

13.

A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens.

Reiling, Jan H; Olive, Andrew J; Sanyal, Sumana; Carette, Jan E; Brummelkamp, Thijn R; Ploegh, Hidde L; Starnbach, Michael N; Sabatini, David M.

Nat Cell Biol; 15(12): 1473-85, 2013 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-24185178

14.

AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer.

Vasudevan, Krishna M; Barbie, David A; Davies, Michael A; Rabinovsky, Rosalia; McNear, Chontelle J; Kim, Jessica J; Hennessy, Bryan T; Tseng, Hsiuyi; Pochanard, Panisa; Kim, So Young; Dunn, Ian F; Schinzel, Anna C; Sandy, Peter; Hoersch, Sebastian; Sheng, Qing; Gupta, Piyush B; Boehm, Jesse S; Reiling, Jan H; Silver, Serena; Lu, Yiling; Stemke-Hale, Katherine; Dutta, Bhaskar; Joy, Corwin; Sahin, Aysegul A; Gonzalez-Angulo, Ana Maria; Lluch, Ana; Rameh, Lucia E; Jacks, Tyler; Root, David E; Lander, Eric S; Mills, Gordon B; Hahn, William C; Sellers, William R; Garraway, Levi A.

Cancer Cell; 16(1): 21-32, 2009 Jul 07.

Artículo en Inglés | MEDLINE | ID: mdl-19573809

15.

The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila.

Reiling, Jan H; Hafen, Ernst.

Genes Dev; 18(23): 2879-92, 2004 Dec 01.

Artículo en Inglés | MEDLINE | ID: mdl-15545626

16.

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex.

Brugarolas, James; Lei, Kui; Hurley, Rebecca L; Manning, Brendan D; Reiling, Jan H; Hafen, Ernst; Witters, Lee A; Ellisen, Leif W; Kaelin, William G.

Genes Dev; 18(23): 2893-904, 2004 Dec 01.

Artículo en Inglés | MEDLINE | ID: mdl-15545625

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