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1.
Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function.
Nat Chem Biol;
8(11): 920-5, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23023261
2.
ASTX029, a Novel Dual-mechanism ERK Inhibitor, Modulates Both the Phosphorylation and Catalytic Activity of ERK.
Mol Cancer Ther;
20(10): 1757-1768, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34330842
3.
AT9283, a potent inhibitor of the Aurora kinases and Jak2, has therapeutic potential in myeloproliferative disorders.
Br J Haematol;
150(1): 46-57, 2010 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-20507304
4.
Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441.
Cancer Res;
66(10): 5354-62, 2006 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16707462
5.
Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinase.
J Med Chem;
50(8): 1958-72, 2007 Apr 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-17371003
6.
Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1.
Cancer Res;
63(18): 6008-15, 2003 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-14522929
7.
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM.
Cancer Res;
64(24): 9152-9, 2004 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15604286
8.
1-substituted (Dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-ones endowed with dual DNA-PK/PI3-K inhibitory activity.
J Med Chem;
56(16): 6386-401, 2013 Aug 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-23855836
9.
Chemosensitization of cancer cells by KU-0060648, a dual inhibitor of DNA-PK and PI-3K.
Mol Cancer Ther;
11(8): 1789-98, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22576130
10.
DNA-dependent protein kinase (DNA-PK) inhibitors. Synthesis and biological activity of quinolin-4-one and pyridopyrimidin-4-one surrogates for the chromen-4-one chemotype.
J Med Chem;
53(24): 8498-507, 2010 Dec 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-21080722
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