Detalles de la búsqueda
1.
Simplified ex-vivo drug evaluation in ocular surface cells: Culture on cellulose filters of cells obtained by impression cytology.
Exp Eye Res;
213: 108827, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34742691
2.
Phospho-valproic acid (MDC-1112) reduces pancreatic cancer growth in patient-derived tumor xenografts and KPC mice: enhanced efficacy when combined with gemcitabine.
Carcinogenesis;
41(7): 927-939, 2020 07 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-31584613
3.
Phospho-valproic acid (MDC-1112) suppresses glioblastoma growth in preclinical models through the inhibition of STAT3 phosphorylation.
Carcinogenesis;
40(12): 1480-1491, 2019 12 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-30994173
4.
The novel agent phospho-glycerol-ibuprofen-amide (MDC-330) inhibits glioblastoma growth in mice: an effect mediated by cyclin D1.
Carcinogenesis;
37(4): 420-429, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26905586
5.
Repurposing the antipsychotic trifluoperazine as an antimetastasis agent.
Mol Pharmacol;
87(3): 501-12, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25552486
6.
The evolving role of nonsteroidal anti-inflammatory drugs in colon cancer prevention: a cause for optimism.
J Pharmacol Exp Ther;
353(1): 2-8, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25589413
7.
Phospho-NSAIDs have enhanced efficacy in mice lacking plasma carboxylesterase: implications for their clinical pharmacology.
Pharm Res;
32(5): 1663-75, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25392229
8.
Pegylation improves the pharmacokinetics and bioavailability of small-molecule drugs hydrolyzable by esterases: a study of phospho-Ibuprofen.
J Pharmacol Exp Ther;
351(1): 61-6, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25047517
9.
Phospho-aspirin (MDC-22) inhibits breast cancer in preclinical animal models: an effect mediated by EGFR inhibition, p53 acetylation and oxidative stress.
BMC Cancer;
14: 141, 2014 Feb 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-24575839
10.
The anticancer effect of phospho-tyrosol-indomethacin (MPI-621), a novel phosphoderivative of indomethacin: in vitro and in vivo studies.
Carcinogenesis;
34(4): 943-51, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23338686
11.
FT-IR microspectroscopy of mouse colon tissues: insight into the chemistry of carcinogenesis and diagnostic potential.
Am J Pathol;
181(6): 1961-8, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23063512
12.
Phosphosulindac (OXT-328) selectively targets breast cancer stem cells in vitro and in human breast cancer xenografts.
Stem Cells;
30(10): 2065-75, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22653497
13.
Topically applied phospho-sulindac hydrogel is efficacious and safe in the treatment of experimental arthritis in rats.
Pharm Res;
30(6): 1471-82, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23483440
14.
The Antiangiogenic Effect and Ocular Pharmacology of Novel Modified Nonsteroidal Anti-Inflammatory Drugs in the Treatment of Oxygen-Induced Retinopathy.
J Ocul Pharmacol Ther;
39(4): 279-289, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37172294
15.
Phosphosulindac (OXT-328) prevents and reverses chemotherapy induced peripheral neuropathy in mice.
Front Neurosci;
17: 1240372, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38347876
16.
Phospho-ibuprofen (MDC-917) suppresses breast cancer growth: an effect controlled by the thioredoxin system.
Breast Cancer Res;
14(1): R20, 2012 Jan 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-22293394
17.
Preclinical predictors of anticancer drug efficacy: critical assessment with emphasis on whether nanomolar potency should be required of candidate agents.
J Pharmacol Exp Ther;
341(3): 572-8, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22448039
18.
Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity.
J Pharmacol Exp Ther;
340(2): 422-32, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22085648
19.
Sterically stabilized liposomes incorporating the novel anticancer agent phospho-ibuprofen (MDC-917): preparation, characterization, and in vitro/in vivo evaluation.
Pharm Res;
29(6): 1435-43, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22072052
20.
In vitro and in vivo metabolic studies of phospho-aspirin (MDC-22).
Pharm Res;
29(12): 3292-301, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-22782648