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1.
Discovery of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1: optimization of kinase selectivity and pharmacokinetics.
Bioorg Med Chem Lett;
23(16): 4511-6, 2013 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23856049
2.
Discovery and optimization of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1.
Bioorg Med Chem Lett;
23(16): 4517-22, 2013 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23850198
3.
Computational and Functional Analyses of HER2 Mutations Reveal Allosteric Activation Mechanisms and Altered Pharmacologic Effects.
Cancer Res;
83(9): 1531-1542, 2023 05 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35503682
4.
Identification of 5-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)thiophene-2-Carboxamides as Novel and Selective Monoamine Oxidase B Inhibitors Used to Improve Memory and Cognition.
ACS Chem Neurosci;
8(12): 2746-2758, 2017 12 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-28857544
5.
Reversible linkage of two distinct small molecule inhibitors of Myc generates a dimeric inhibitor with improved potency that is active in myc over-expressing cancer cell lines.
PLoS One;
10(4): e0121793, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25875098
6.
A mouse model of Rubinstein-Taybi syndrome: defective long-term memory is ameliorated by inhibitors of phosphodiesterase 4.
Proc Natl Acad Sci U S A;
100(18): 10518-22, 2003 Sep 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-12930888
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