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1.
Discovery of 4'-azido-2'-deoxy-2'-C-methyl cytidine and prodrugs thereof: a potent inhibitor of Hepatitis C virus replication.
Bioorg Med Chem Lett;
22(9): 3265-8, 2012 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22472694
2.
Investigation of α-phenylnorstatine and α-benzylnorstatine as transition state isostere motifs in the search for new BACE-1 inhibitors.
Bioorg Med Chem;
19(1): 145-55, 2011 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21183353
3.
Synthesis and SAR of potent inhibitors of the Hepatitis C virus NS3/4A protease: exploration of P2 quinazoline substituents.
Bioorg Med Chem Lett;
20(14): 4004-11, 2010 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20541405
4.
Discovery of potent BACE-1 inhibitors containing a new hydroxyethylene (HE) scaffold: exploration of P1' alkoxy residues and an aminoethylene (AE) central core.
Bioorg Med Chem;
18(4): 1711-23, 2010 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20122837
5.
Discovery of novel potent and selective dipeptide hepatitis C virus NS3/4A serine protease inhibitors.
Bioorg Med Chem Lett;
18(18): 5095-100, 2008 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18722116
6.
Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues.
Bioorg Med Chem;
16(21): 9471-86, 2008 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18842420
7.
Synthesis of novel potent hepatitis C virus NS3 protease inhibitors: discovery of 4-hydroxy-cyclopent-2-ene-1,2-dicarboxylic acid as a N-acyl-L-hydroxyproline bioisostere.
Bioorg Med Chem;
15(2): 827-38, 2007 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17107807
8.
Novel potent macrocyclic inhibitors of the hepatitis C virus NS3 protease: use of cyclopentane and cyclopentene P2-motifs.
Bioorg Med Chem;
15(22): 7184-202, 2007 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17845856
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