Detalles de la búsqueda
1.
Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys.
Nature;
531(7594): 381-5, 2016 Mar 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-26934220
2.
Soft-tissue profile growth in patients with repaired complete unilateral cleft lip and palate: A cephalometric comparison with normal controls at ages 7, 11, and 18 years.
Am J Orthod Dentofacial Orthop;
145(3): 341-58, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24582026
3.
Closed genomes of four multidrug resistance Salmonella enterica serotype Infantis isolated in Costa Rica.
Microbiol Resour Announc;
13(1): e0025723, 2024 Jan 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38019019
4.
Rapid differentiation of nucleotide phosphoramidate diastereomers by electrospray ionization tandem mass spectrometry.
Rapid Commun Mass Spectrom;
26(16): 1887-92, 2012 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-22777791
5.
ß-D-2'-α-F-2'-ß-C-Methyl-6-O-substituted 3',5'-cyclic phosphate nucleotide prodrugs as inhibitors of hepatitis C virus replication: a structure-activity relationship study.
Bioorg Med Chem Lett;
22(18): 5924-9, 2012 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22892115
6.
A liquid chromatography-tandem mass spectrometry method for the quantitative determination of diastereomers of a phosphoramidate nucleotide prodrug (PSI-7851) in human plasma.
Biomed Chromatogr;
26(5): 583-8, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21842514
7.
A Chemical Approach to Introduce 2,6-Diaminopurine and 2-Aminoadenine Conjugates into Oligonucleotides without Need for Protecting Groups.
Org Lett;
24(33): 6111-6116, 2022 08 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-35973215
8.
Synthesis of diastereomerically pure nucleotide phosphoramidates.
J Org Chem;
76(20): 8311-9, 2011 Oct 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-21916475
9.
Stereoselective synthesis of PSI-352938: a ß-D-2'-deoxy-2'-α-fluoro-2'-ß-C-methyl-3',5'-cyclic phosphate nucleotide prodrug for the treatment of HCV.
J Org Chem;
76(10): 3782-90, 2011 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-21469736
10.
PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication.
Antimicrob Agents Chemother;
54(8): 3187-96, 2010 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-20516278
11.
Synthesis and anti-HCV activity of 3',4'-oxetane nucleosides.
Bioorg Med Chem Lett;
20(15): 4539-43, 2010 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20580554
12.
2'-deoxy-2'-α-fluoro-2'-ß-C-methyl 3',5'-cyclic phosphate nucleotide prodrug analogs as inhibitors of HCV NS5B polymerase: discovery of PSI-352938.
Bioorg Med Chem Lett;
20(24): 7376-80, 2010 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21050754
13.
An efficient and diastereoselective synthesis of PSI-6130: a clinically efficacious inhibitor of HCV NS5B polymerase.
J Org Chem;
74(17): 6819-24, 2009 Sep 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-19642660
14.
BASC: an integrated bioinformatics system for Brassica research.
Nucleic Acids Res;
35(Database issue): D870-3, 2007 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17148473
15.
Comparing in vitro and in vivo activity of 2'-O-[2-(methylamino)-2-oxoethyl]- and 2'-O-methoxyethyl-modified antisense oligonucleotides.
J Med Chem;
51(9): 2766-76, 2008 May 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-18399648
16.
An efficient and scalable synthesis of 2,6-diaminopurine riboside.
Nucleosides Nucleotides Nucleic Acids;
27(1): 67-9, 2008 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18188771
17.
Permanent maxillary central incisor and first molar rotations in the mixed dentition in repaired complete unilateral cleft lip and palate and their relationship with absence of teeth in their vicinity.
Angle Orthod;
88(5): 567-574, 2018 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-29799271
18.
Incisor and molar overjet, arch contraction, and molar relationship in the mixed dentition in repaired complete unilateral cleft lip and palate: A qualitative and quantitative appraisal.
Angle Orthod;
87(4): 603-609, 2017 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-28195497
19.
Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses.
J Med Chem;
60(5): 1648-1661, 2017 03 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28124907
20.
Efficient large-scale synthesis of 5'-O-dimethoxytrityl-N4-benzoyl-5-methyl-2'-deoxycytidine.
Nucleosides Nucleotides Nucleic Acids;
25(7): 765-70, 2006.
Artículo
en Inglés
| MEDLINE | ID: mdl-16898414