Detalles de la búsqueda
1.
A Phase 2 Study of Pimodivir (JNJ-63623872) in Combination With Oseltamivir in Elderly and Nonelderly Adults Hospitalized With Influenza A Infection: OPAL Study.
J Infect Dis;
226(1): 109-118, 2022 08 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32604406
2.
Linking In Vitro Intrinsic Dissolution Rate and Thermodynamic Solubility with Pharmacokinetic Profiles of Bedaquiline Long-Acting Aqueous Microsuspensions in Rats.
Mol Pharm;
18(3): 952-965, 2021 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33400546
3.
A Population Pharmacokinetic Model for a Solid Oral Tablet Formulation of Posaconazole.
Antimicrob Agents Chemother;
62(7)2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29712663
4.
The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women.
Drug Metab Dispos;
44(9): 1450-8, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27402726
5.
Evaluation of efficacy and safety of the anti-VWF Nanobody ALX-0681 in a preclinical baboon model of acquired thrombotic thrombocytopenic purpura.
Blood;
120(17): 3603-10, 2012 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-22948047
6.
Antithrombotic drug candidate ALX-0081 shows superior preclinical efficacy and safety compared with currently marketed antiplatelet drugs.
Blood;
118(3): 757-65, 2011 Jul 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-21576702
7.
Population pharmacokinetics and pharmacodynamics of rivaroxaban in patients with acute coronary syndromes.
Br J Clin Pharmacol;
74(1): 86-97, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22242932
8.
A time scaling approach to develop an in vitro-in vivo correlation (IVIVC) model using a convolution-based technique.
J Pharmacokinet Pharmacodyn;
38(5): 519-39, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-21735135
9.
Exposure-safety analysis of QTc interval and transaminase levels following bedaquiline administration in patients with drug-resistant tuberculosis.
CPT Pharmacometrics Syst Pharmacol;
10(12): 1538-1549, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34626526
10.
Population Pharmacokinetic Analysis of Bedaquiline-Clarithromycin for Dose Selection Against Pulmonary Nontuberculous Mycobacteria Based on a Phase 1, Randomized, Pharmacokinetic Study.
J Clin Pharmacol;
61(10): 1344-1355, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33991350
11.
Population Pharmacokinetics of Esketamine Nasal Spray and its Metabolite Noresketamine in Healthy Subjects and Patients with Treatment-Resistant Depression.
Clin Pharmacokinet;
60(4): 501-516, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33128208
12.
Combined models for data from in vitro-in vivo correlation experiments.
J Biopharm Stat;
18(6): 1197-211, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18991117
13.
Identification of the PXW sequence as a structural gatekeeper of the headpiece C-terminal subdomain fold.
J Mol Biol;
359(5): 1277-92, 2006 Jun 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-16697408
14.
Dosing and Switching Strategies for Paliperidone Palmitate 3-Month Formulation in Patients with Schizophrenia Based on Population Pharmacokinetic Modeling and Simulation, and Clinical Trial Data.
CNS Drugs;
31(4): 273-288, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-28258365
15.
Population Pharmacokinetics of a Novel Once-Every 3 Months Intramuscular Formulation of Paliperidone Palmitate in Patients with Schizophrenia.
Clin Pharmacokinet;
56(4): 421-433, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-27743205
16.
The effect of macrophage and angiogenesis inhibition on the drug release and absorption from an intramuscular sustained-release paliperidone palmitate suspension.
J Control Release;
230: 95-108, 2016 05 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-27067365
17.
Pharmacokinetic profile after multiple deltoid or gluteal intramuscular injections of paliperidone palmitate in patients with schizophrenia.
Clin Pharmacol Drug Dev;
4(4): 270-8, 2015 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27136907
18.
Development of in vitro-in vivo correlation for extended-release niacin after administration of hypromellose-based matrix formulations to healthy volunteers.
J Pharm Sci;
103(11): 3713-3723, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25256703
19.
A single-dose, open-label, parallel, randomized, dose-proportionality study of paliperidone after intramuscular injections of paliperidone palmitate in the deltoid or gluteal muscle in patients with schizophrenia.
J Clin Pharmacol;
54(9): 1048-57, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24676998
20.
D2-receptor occupancy measurement of JNJ-37822681, a novel fast off-rate D2-receptor antagonist, in healthy subjects using positron emission tomography: single dose versus steady state and dose selection.
Psychopharmacology (Berl);
224(4): 549-57, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-22773165