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1.

In Silico Labeling: Predicting Fluorescent Labels in Unlabeled Images.

Christiansen, Eric M; Yang, Samuel J; Ando, D Michael; Javaherian, Ashkan; Skibinski, Gaia; Lipnick, Scott; Mount, Elliot; O'Neil, Alison; Shah, Kevan; Lee, Alicia K; Goyal, Piyush; Fedus, William; Poplin, Ryan; Esteva, Andre; Berndl, Marc; Rubin, Lee L; Nelson, Philip; Finkbeiner, Steven.

Cell; 173(3): 792-803.e19, 2018 04 19.

Artículo en Inglés | MEDLINE | ID: mdl-29656897

2.

Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics.

Ordureau, Alban; Paulo, Joao A; Zhang, Wei; Ahfeldt, Tim; Zhang, Jiuchun; Cohn, Erin F; Hou, Zhonggang; Heo, Jin-Mi; Rubin, Lee L; Sidhu, Sachdev S; Gygi, Steven P; Harper, J Wade.

Mol Cell; 70(2): 211-227.e8, 2018 04 19.

Artículo en Inglés | MEDLINE | ID: mdl-29656925

3.

Stem cells and drug discovery: the beginning of a new era?

Rubin, Lee L.

Cell; 132(4): 549-52, 2008 Feb 22.

Artículo en Inglés | MEDLINE | ID: mdl-18295572

4.

Accelerating diagnosis of Parkinson's disease through risk prediction.

Yuan, William; Beaulieu-Jones, Brett; Krolewski, Richard; Palmer, Nathan; Veyrat-Follet, Christine; Frau, Francesca; Cohen, Caroline; Bozzi, Sylvie; Cogswell, Meaghan; Kumar, Dinesh; Coulouvrat, Catherine; Leroy, Bruno; Fischer, Tanya Z; Sardi, S Pablo; Chandross, Karen J; Rubin, Lee L; Wills, Anne-Marie; Kohane, Isaac; Lipnick, Scott L.

BMC Neurol; 21(1): 201, 2021 May 18.

Artículo en Inglés | MEDLINE | ID: mdl-34006233

5.

Material microenvironmental properties couple to induce distinct transcriptional programs in mammalian stem cells.

Darnell, Max; O'Neil, Alison; Mao, Angelo; Gu, Luo; Rubin, Lee L; Mooney, David J.

Proc Natl Acad Sci U S A; 115(36): E8368-E8377, 2018 09 04.

Artículo en Inglés | MEDLINE | ID: mdl-30120125

6.

Genetic modifiers ameliorate endocytic and neuromuscular defects in a model of spinal muscular atrophy.

Walsh, Melissa B; Janzen, Eva; Wingrove, Emily; Hosseinibarkooie, Seyyedmohsen; Muela, Natalia Rodriguez; Davidow, Lance; Dimitriadi, Maria; Norabuena, Erika M; Rubin, Lee L; Wirth, Brunhilde; Hart, Anne C.

BMC Biol; 18(1): 127, 2020 09 16.

Artículo en Inglés | MEDLINE | ID: mdl-32938453

7.

Biochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future Investigation.

Walker, Ryan G; Poggioli, Tommaso; Katsimpardi, Lida; Buchanan, Sean M; Oh, Juhyun; Wattrus, Sam; Heidecker, Bettina; Fong, Yick W; Rubin, Lee L; Ganz, Peter; Thompson, Thomas B; Wagers, Amy J; Lee, Richard T.

Circ Res; 118(7): 1125-41; discussion 1142, 2016 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-27034275

8.

Notch inhibition allows oncogene-independent generation of iPS cells.

Ichida, Justin K; Tcw, Julia; Williams, Luis A; Carter, Ava C; Shi, Yingxiao; Moura, Marcelo T; Ziller, Michael; Singh, Sean; Amabile, Giovanni; Bock, Christoph; Umezawa, Akihiro; Rubin, Lee L; Bradner, James E; Akutsu, Hidenori; Meissner, Alexander; Eggan, Kevin.

Nat Chem Biol; 10(8): 632-639, 2014 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-24952596

9.

Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy.

Sen, Anindya; Dimlich, Douglas N; Guruharsha, K G; Kankel, Mark W; Hori, Kazuya; Yokokura, Takakazu; Brachat, Sophie; Richardson, Delwood; Loureiro, Joseph; Sivasankaran, Rajeev; Curtis, Daniel; Davidow, Lance S; Rubin, Lee L; Hart, Anne C; Van Vactor, David; Artavanis-Tsakonas, Spyros.

Proc Natl Acad Sci U S A; 110(26): E2371-80, 2013 Jun 25.

Artículo en Inglés | MEDLINE | ID: mdl-23757500

10.

Adenosine kinase inhibition selectively promotes rodent and porcine islet ß-cell replication.

Annes, Justin P; Ryu, Jennifer Hyoje; Lam, Kelvin; Carolan, Peter J; Utz, Katrina; Hollister-Lock, Jennifer; Arvanites, Anthony C; Rubin, Lee L; Weir, Gordon; Melton, Douglas A.

Proc Natl Acad Sci U S A; 109(10): 3915-20, 2012 Mar 06.

Artículo en Inglés | MEDLINE | ID: mdl-22345561

11.

A paracrine requirement for hedgehog signalling in cancer.

Yauch, Robert L; Gould, Stephen E; Scales, Suzie J; Tang, Tracy; Tian, Hua; Ahn, Christina P; Marshall, Derek; Fu, Ling; Januario, Thomas; Kallop, Dara; Nannini-Pepe, Michelle; Kotkow, Karen; Marsters, James C; Rubin, Lee L; de Sauvage, Frederic J.

Nature; 455(7211): 406-10, 2008 Sep 18.

Artículo en Inglés | MEDLINE | ID: mdl-18754008

12.

Hepatocyte-intrinsic SMN deficiency drives metabolic dysfunction and liver steatosis in spinal muscular atrophy.

Leow, Damien Meng-Kiat; Ng, Yang Kai; Wang, Loo Chien; Koh, Hiromi Wl; Zhao, Tianyun; Khong, Zi Jian; Tabaglio, Tommaso; Narayanan, Gunaseelan; Giadone, Richard M; Sobota, Radoslaw M; Ng, Shi-Yan; Teo, Adrian Kk; Parson, Simon H; Rubin, Lee L; Ong, Wei-Yi; Darras, Basil T; Yeo, Crystal Jj.

J Clin Invest; 2024 May 09.

Artículo en Inglés | MEDLINE | ID: mdl-38722695

13.

A cell-autonomous defect in skeletal muscle satellite cells expressing low levels of survival of motor neuron protein.

Hayhurst, Monica; Wagner, Amanda K; Cerletti, Massimiliano; Wagers, Amy J; Rubin, Lee L.

Dev Biol; 368(2): 323-34, 2012 Aug 15.

Artículo en Inglés | MEDLINE | ID: mdl-22705478

14.

A screen for regulators of survival of motor neuron protein levels.

Makhortova, Nina R; Hayhurst, Monica; Cerqueira, Antonio; Sinor-Anderson, Amy D; Zhao, Wen-Ning; Heiser, Patrick W; Arvanites, Anthony C; Davidow, Lance S; Waldon, Zachary O; Steen, Judith A; Lam, Kelvin; Ngo, Hien D; Rubin, Lee L.

Nat Chem Biol; 7(8): 544-52, 2011 Jun 19.

Artículo en Inglés | MEDLINE | ID: mdl-21685895

15.

miRNA malfunction causes spinal motor neuron disease.

Haramati, Sharon; Chapnik, Elik; Sztainberg, Yehezkel; Eilam, Raya; Zwang, Raaya; Gershoni, Noga; McGlinn, Edwina; Heiser, Patrick W; Wills, Anne-Marie; Wirguin, Itzhak; Rubin, Lee L; Misawa, Hidemi; Tabin, Clifford J; Brown, Robert; Chen, Alon; Hornstein, Eran.

Proc Natl Acad Sci U S A; 107(29): 13111-6, 2010 Jul 20.

Artículo en Inglés | MEDLINE | ID: mdl-20616011

16.

Implementation of a Drug Screening Platform to TargetGch1 Expression in Injured Mouse Dorsal Root Ganglion Neurons.

Cronin, Shane J F; Davidow, Lance S; Arvanites, Anthony C; Rubin, Lee L; Penninger, Josef M; Woolf, Clifford J.

Bio Protoc; 13(9): e4666, 2023 May 05.

Artículo en Inglés | MEDLINE | ID: mdl-37188109

17.

GDF11 and aging biology - controversies resolved and pending.

Driss, Laura Ben; Lian, John; Walker, Ryan G; Howard, James A; Thompson, Thomas B; Rubin, Lee L; Wagers, Amy J; Lee, Richard T.

J Cardiovasc Aging; 3(4)2023 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-38235060

18.

Analyzing the ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets.

Watts, Michelle E; Giadone, Richard M; Ordureau, Alban; Holton, Kristina M; Harper, J Wade; Rubin, Lee L.

Front Cell Neurosci; 17: 1327361, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-38314348

19.

High-content synaptic phenotyping in human cellular models reveals a role for BET proteins in synapse assembly.

Berryer, Martin H; Rizki, Gizem; Nathanson, Anna; Klein, Jenny A; Trendafilova, Darina; Susco, Sara G; Lam, Daisy; Messana, Angelica; Holton, Kristina M; Karhohs, Kyle W; Cimini, Beth A; Pfaff, Kathleen; Carpenter, Anne E; Rubin, Lee L; Barrett, Lindy E.

Elife; 122023 04 21.

Artículo en Inglés | MEDLINE | ID: mdl-37083703

20.

A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides.

Paul, Kimberly C; Krolewski, Richard C; Lucumi Moreno, Edinson; Blank, Jack; Holton, Kristina M; Ahfeldt, Tim; Furlong, Melissa; Yu, Yu; Cockburn, Myles; Thompson, Laura K; Kreymerman, Alexander; Ricci-Blair, Elisabeth M; Li, Yu Jun; Patel, Heer B; Lee, Richard T; Bronstein, Jeff; Rubin, Lee L; Khurana, Vikram; Ritz, Beate.

Nat Commun; 14(1): 2803, 2023 05 16.

Artículo en Inglés | MEDLINE | ID: mdl-37193692

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