RESUMEN
Low- and ultralow-energy tightly focused 200 fs, 515 nm donut-shaped laser pulses at 0.25 and 0.65 NA focusing were used for single-shot ablative pulse-energy scalable nanopatterning of 50 nm thick gold film and the following plasmonic excitation of dye monolayer photoluminescence (PL) in the fabricated nanostructures, respectively. The same pulses at much lower, non-ablative nanojoule energies, and the same focusing and linear, azimuthal, or radial polarizations provided efficient spectrally and symmetry-matched excitation of both localized and delocalized surface electromagnetic modes in the separate, ring-like through holes and their arrays in the film envisioned by our modeling, thus resulting in a polarization-sensitive yield of rhodamine 6G dye PL. The demonstrated consistency between the symmetries of the donut-shaped low-energy photo-exciting laser beam, its polarization state, and the donut-shaped gold nanostructures, produced by the same beam at high, ablative pulse energies, paves the way to smart, self-consistent nanofabrication and plasmonic sensing, when the structured light interacts with the consistently structured matter.
RESUMEN
In this work, we demonstrate an all-laser method of fabrication of optical nanoantennas (ONAs) with an additional coupling/focusing diffractive element. This method is based on double-shot femtosecond laser nanoablation of a thin supported metallic film, inducing a sequence of electrodynamic (surface plasmon-polariton [SPP] excitation and interference), thermal (melting, ablation and ultrafast cooling), and hydrodynamic processes. In particular, the thermal and hydrodynamic processes are important for ONA formation after the first laser shot, while second spatially shifted laser shot via an induced SPP wave results in a radial surface grating near the nanoantenna. Such gratings provide efficient coupling between incident laser radiation and SPP waves, thus significantly improving the ONA efficiency.
RESUMEN
The decisive factor in the appearance of postinfection abscesses is the presence of damaged tissues, open to the penetration of microorganisms not only by the exogenic or endogenic route, but also by the so-called exoendogenic route, when they penetrate the body from the air via the upper respiratory ways and further into the blood and damaged tissues.
Asunto(s)
Absceso/etiología , Inyecciones/efectos adversos , Infecciones por Pseudomonas/etiología , Infecciones Estafilocócicas/etiología , Absceso/microbiología , Animales , Ratones , Infecciones por Pseudomonas/microbiología , Pseudomonas aeruginosa/aislamiento & purificación , Sepsis/etiología , Sepsis/microbiología , Infecciones Estafilocócicas/microbiología , Staphylococcus aureus/aislamiento & purificación , Factores de TiempoRESUMEN
Data are reported of 582 case records of patients with acute pneumonia of different influenza epidemic periods, results of a study of 175 lethal cases due to acute pneumonia, that complicated influenza in adults as well as experimental studies on reproduction of para-influenzal-staphylococcal, influenzal-Klebsiella and Proteus-influenzal infections. The study allowed to find out the causes of diagnostic difficulties, to establish the features of the course of acute pneumonia in patients with respiratory viral diseases to disclose the mechanisms of development of lung changes and make propositions facilitating early clinical diagnosis on the prehospital period.
Asunto(s)
Neumonía Viral/etiología , Neumonía/etiología , Infecciones del Sistema Respiratorio/complicaciones , Enfermedad Aguda , Adulto , Animales , Cricetinae , Diagnóstico Diferencial , Humanos , Pulmón/patología , Mesocricetus , Neumonía/diagnóstico , Neumonía/patología , Neumonía Viral/diagnóstico , Neumonía Viral/patología , Infecciones del Sistema Respiratorio/diagnóstico , Infecciones del Sistema Respiratorio/patologíaRESUMEN
Results are reported of a study of 46 patients with systemic diseases: connective tissue, inflammatory granulomatous processes, lymphoid tissue lesions and blood diseases treated in the clinic of infections diseases. Difficulties and errors in their clinical diagnosis, and their causes are shown. It is emphasized that these patients are hospitalized in infections clinics and that the incidence of systemic diseases rises in conditions of radiation environment.
Asunto(s)
Enfermedades Transmisibles/diagnóstico , Hospitales Especializados , Medicina Interna , Adulto , Diagnóstico Diferencial , Errores Diagnósticos , Femenino , Humanos , Masculino , Persona de Mediana Edad , UcraniaRESUMEN
Administration of laferon to patients stimulates the blood serum interferon formation, with its peak being reached by 24 h. The evaluation done confirmed the therapeutic efficacy of laferon in meningoencephalites. This was manifested by reduction in duration of certain clinical symptoms, timeterms of spinal fluid sanitation, improvement in immunity parameters and increase in the patients' blood serum level of interferon.
Asunto(s)
Infecciones por Adenovirus Humanos/terapia , Antivirales/uso terapéutico , Infecciones por Enterovirus/terapia , Infecciones por Herpesviridae/terapia , Gripe Humana/terapia , Interferón Tipo I/uso terapéutico , Meningoencefalitis/terapia , Infecciones por Adenovirus Humanos/inmunología , Adulto , Evaluación de Medicamentos , Infecciones por Enterovirus/inmunología , Femenino , Infecciones por Herpesviridae/inmunología , Humanos , Inmunidad Celular/inmunología , Gripe Humana/inmunología , Interferones/sangre , Interferones/efectos de los fármacos , Masculino , Meningoencefalitis/inmunología , Persona de Mediana Edad , Proteínas Recombinantes , Formación de Roseta , Factores de TiempoAsunto(s)
Antiinfecciosos/uso terapéutico , Enfermedades Transmisibles/tratamiento farmacológico , Ofloxacino/uso terapéutico , Enfermedad Aguda , Adulto , Antiinfecciosos/farmacología , Bacterias/efectos de los fármacos , Enfermedades Transmisibles/sangre , Femenino , Humanos , Interferones/sangre , Interferones/efectos de los fármacos , Masculino , Pruebas de Sensibilidad Microbiana , Persona de Mediana Edad , Ofloxacino/farmacología , Factores de TiempoAsunto(s)
Materiales de Construcción , Resinas Sintéticas , Urea/análisis , Formaldehído/análisis , Humedad , VolatilizaciónAsunto(s)
Hipotermia Inducida , Insuficiencia de la Válvula Mitral/cirugía , Intercambio Gaseoso Pulmonar , Equilibrio Ácido-Base , Adulto , Anestesia General , Fibrilación Atrial/etiología , Fibrilación Atrial/fisiopatología , Femenino , Prótesis Valvulares Cardíacas , Hemodinámica , Humanos , Hipotermia Inducida/métodos , Masculino , Persona de Mediana Edad , Válvula Mitral , Insuficiencia de la Válvula Mitral/complicaciones , Insuficiencia de la Válvula Mitral/fisiopatologíaAsunto(s)
Hipotermia Inducida , Consumo de Oxígeno , Equilibrio Ácido-Base , Adolescente , Adulto , Análisis de los Gases de la Sangre , Temperatura Corporal , Niño , Preescolar , Ensayos Clínicos como Asunto , Femenino , Glucólisis , Cardiopatías Congénitas/sangre , Cardiopatías Congénitas/cirugía , Humanos , Masculino , Persona de Mediana Edad , Presión ParcialRESUMEN
The craving for alcohol was studied using 2 Russian and 4 international scales, including ratings of the clinician and self-rating of the patient. Depression and anxiety as well as the content of alcohol in exhaled air were assessed. The data were compared to the scores of the Impulsive Relapse Questionnaire. Eighteen patients were studied. The prolonged conscious or insurmountable or poorly controlled drive for alcohol was rare in patients in the remission. Most of patients do not notice such a drive though it was found with the corresponding scales. The craving for alcohol is more often caused by the environment factors related as to alcohol as well to non-specific stress factors and represents a transient impulsive phenomenon that leads to the relapse of disease.
Asunto(s)
Consumo de Bebidas Alcohólicas/efectos adversos , Alcoholismo/etiología , Adulto , Alcoholismo/diagnóstico , Estudios de Seguimiento , Humanos , Pronóstico , Recurrencia , Índice de Severidad de la Enfermedad , Estrés Psicológico/complicaciones , Estrés Psicológico/diagnóstico , Encuestas y CuestionariosRESUMEN
Of 1125 patients with acute respiratory diseases (complicated) and uncomplicated 49 (4.4%) showed infection caused by Mycoplasma hominis. The diagnosis was established by serological and microbiological methods. The authors describe the microbiological method of detection of the pathogen in nasopharyngeal wash offs and sputum. Illustrative clinical examples are presented.
Asunto(s)
Infecciones por Mycoplasma/diagnóstico , Enfermedad Aguda , Adolescente , Adulto , Anticuerpos Antibacterianos/análisis , Especificidad de Anticuerpos , Antígenos Bacterianos/análisis , Humanos , Masculino , Persona de Mediana Edad , Mycoplasma/inmunología , Infecciones por Mycoplasma/etiología , Infecciones por Mycoplasma/patología , Neumonía por Mycoplasma/diagnóstico , Neumonía por Mycoplasma/etiología , Neumonía por Mycoplasma/patologíaRESUMEN
Data are reported of the results of clinical trials of the therapeutic efficacy of longaceph--a drug of the new generation of cephalosporins with a long period of half-decay--in acute pneumonia complicating influenza in 42 patients. The sensitivity of 120 microbial strains to longaceph was also studied. It was established that cephalosporin possesses a high efficacy in diseases caused by gram-positive and gram-negative microorganisms. A high degree of sensitivity to longaceph was observed in pneumococci biogenous and Streptococcus viridans, Staphylococcus aureus and epidermidis, klebsiellae and escherichiae. A new property of longaceph was found, namely, its capacity to stimulate the formation of endogenous interferon.
Asunto(s)
Ceftriaxona/uso terapéutico , Cefalosporinas/uso terapéutico , Adulto , Infecciones Bacterianas/sangre , Infecciones Bacterianas/tratamiento farmacológico , Infecciones Bacterianas/microbiología , ADN/sangre , ADN/efectos de los fármacos , Reparación del ADN/efectos de los fármacos , Preparaciones de Acción Retardada , Evaluación de Medicamentos , Bacterias Gramnegativas/efectos de los fármacos , Bacterias Grampositivas/efectos de los fármacos , Humanos , Interferones/sangre , Linfocitos/efectos de los fármacos , Linfocitos/metabolismo , Pruebas de Sensibilidad Microbiana , Persona de Mediana Edad , Neumonía/sangre , Neumonía/tratamiento farmacológico , Neumonía/microbiologíaRESUMEN
DNA packing of bacteriophage phikz (Pseudomonas aeruginosa) was studied by electron microscopy after gentle destruction of the capsid with powerful laser impulse in aqueous virus suspension in the presence organic dye. Suspension of destroyed phage heads contained complexes of genomic DNA with endogenous capsid proteins characterized by pronounced regular structure. The type of these structures corresponds to one the main model of phage DNA packing, the so-called coil packing.