Detalles de la búsqueda
1.
Preclinical pharmacokinetics and tolerability of a novel meglumine-based parenteral solution of topiramate and topiramate combinations for treatment of status epilepticus.
Epilepsia;
64(4): 888-899, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36708090
2.
Clinical evaluation of a combination therapy of imepitoin with phenobarbital in dogs with refractory idiopathic epilepsy.
BMC Vet Res;
13(1): 33, 2017 Jan 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-28118828
3.
Novel ubiquitin-derived high affinity binding proteins with tumor targeting properties.
J Biol Chem;
289(12): 8493-507, 2014 Mar 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-24474690
4.
Efficacy, safety, and tolerability of imepitoin in dogs with newly diagnosed epilepsy in a randomized controlled clinical study with long-term follow up.
BMC Vet Res;
11: 228, 2015 Sep 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-26330063
5.
Evaluation of the efficacy of meloxicam for post-operative management of pain and inflammation in horses after orthopaedic surgery in a placebo controlled clinical field trial.
BMC Vet Res;
11: 113, 2015 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25976845
6.
Activity and Safety of Inhaled Itraconazole Nanosuspension in a Model Pulmonary Aspergillus fumigatus Infection in Inoculated Young Quails.
Mycopathologia;
180(1-2): 35-42, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25790942
7.
A model for treating avian aspergillosis: serum and lung tissue kinetics for Japanese quail (Coturnix japonica) following single and multiple aerosol exposures of a nanoparticulate itraconazole suspension.
Med Mycol;
51(8): 800-10, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23815436
8.
The atypical anxiolytic drug, tofisopam, selectively blocks phosphodiesterase isoenzymes and is active in the mouse model of negative symptoms of psychosis.
J Neural Transm (Vienna);
117(11): 1319-25, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-20967473
9.
Imepitoin Shows Benzodiazepine-Like Effects in Models of Anxiety.
Front Pharmacol;
9: 1225, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30455643
10.
The novel anxiolytic ELB139 displays selectivity to recombinant GABA(A) receptors different from diazepam.
Neuropharmacology;
52(3): 796-801, 2007 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-17087982
11.
ELB139 an agonist at the benzodiazepine binding site increases 5-HT in the striatum and prefrontal cortex of rats: a microdialysis study.
Pharmacol Biochem Behav;
86(1): 79-85, 2007 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17257662
12.
New GABA-modulating 1,2,4-oxadiazole derivatives and their anticonvulsant activity.
Eur J Med Chem;
42(6): 873-9, 2007 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-17303289
13.
Synthesis, pharmacology, and structure-activity relationships of novel imidazolones and pyrrolones as modulators of GABAA receptors.
J Med Chem;
49(6): 1855-66, 2006 Mar 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-16539371
14.
Anticonvulsant activity and tolerance of ELB138 in dogs with epilepsy: a clinical pilot study.
Vet J;
172(1): 86-95, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-15905110
15.
The phosphodiesterase 4 inhibitor AWD 12-281 is active in a new guinea-pig model of allergic skin inflammation predictive of human skin penetration and suppresses both Th1 and Th2 cytokines in mice.
J Pharm Pharmacol;
57(12): 1609-17, 2005 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-16354405
16.
Anxiogenic- and antidepressant-like behavior in corneally kindled rats.
Pharmacol Rep;
67(2): 349-52, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25712662
17.
Ubiquitin is a versatile scaffold protein for the generation of molecules with de novo binding and advantageous drug-like properties.
FEBS Open Bio;
5: 579-93, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26258013
18.
AWD 12-281, a highly selective phosphodiesterase 4 inhibitor, is effective in the prevention and treatment of inflammatory reactions in a model of allergic dermatitis.
J Pharm Pharmacol;
55(8): 1107-14, 2003 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-12956900
19.
The pharmacology of imepitoin: the first partial benzodiazepine receptor agonist developed for the treatment of epilepsy.
CNS Drugs;
28(1): 29-43, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24357084
20.
Inhalable highly concentrated itraconazole nanosuspension for the treatment of bronchopulmonary aspergillosis.
Eur J Pharm Biopharm;
83(1): 44-53, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23064325