RESUMEN
OBJECTIVE: To study surgical patients' informational expectations and the level of received knowledge at the time of hospital discharge. To examine if there is an association with postoperative complications and the patient´s level of received knowledge. DESIGN: Comparative descriptive design. SETTING: The data on patients admitted for non-cardiac surgery were collected in three phases during an eight-month period. PARTICIPANTS: 258 in-ward non-cardiac general surgery and orthopedic surgery adult patients. INTERVENTIONS: Questionnaires before admission (knowledge expectations) and at discharge (received knowledge). A telephone interview 30 days after discharge. MAIN OUTCOME MEASURES: Received knowledge (as much or more / less) compared to expectations, and its association with post-discharge complications. RESULTS: There were differences between patient groups in their perception of receiving enough knowledge and they were connected to gender (male vs. female OR 2.67, 95% CI 1.55-4.60, P = 0.0004) and procedure (elective orthopedic implant surgery vs. elective minor orthopedic and hand surgery: OR 3.25, 95% CI 1.72-6.17, P = 0.0003). Patients who received less knowledge than expected had more postoperative complications than those who received sufficient (as much or more than expected) information. CONCLUSIONS: Patients differ in terms of informational needs, and preoperative education prepares the patient for the information provided postoperatively. Patient education may have an influence on recovery from surgery.
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Cirugía General , Procedimientos Ortopédicos/psicología , Educación del Paciente como Asunto/estadística & datos numéricos , Complicaciones Posoperatorias/epidemiología , Anciano , Femenino , Finlandia , Conocimientos, Actitudes y Práctica en Salud , Humanos , Masculino , Persona de Mediana Edad , Encuestas y CuestionariosRESUMEN
PURPOSE: The purpose of this paper is to study the possible inheritance of nasal dermoid sinus cyst in the Finnish population. METHODS: A patient questionnaire and interview were utilized for this study. RESULTS: We identified nine patients with dermoid sinus cyst. Only one of them had familial nasal dermoid sinus cyst. We found no evidence for founder effect. CONCLUSIONS: We report a pedigree with six affected individuals and an association of nasal dermoid sinus cyst and third ventricle colloid cyst. Whether patients or pedigrees with nasal dermoid sinus cyst (NDSC) and third ventricle colloid cysts represent a previously unrecognized syndrome or belong to the normal phenotypic spectrum of NDSC remains unclear. Our patient material suggests that only minority of NDSCs seem to be familial.
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Quiste Coloide/complicaciones , Quiste Dermoide/complicaciones , Neoplasias de los Senos Paranasales/complicaciones , Linaje , Anomalías Múltiples , Adolescente , Adulto , Niño , Preescolar , Susceptibilidad a Enfermedades , Femenino , Finlandia , Humanos , Lactante , Masculino , Encuestas y Cuestionarios , Adulto JovenRESUMEN
OBJECTIVES: Basic tools that measure a hospital's performance are required in order to benchmark or compare hospitals, but multispecialty institutional registries are rarely reported, and there is no consensus on their standard definitions and methodology. This study aimed to describe the setting up and first results of a hospital-wide surgical complication register that uses a minimal set of patient-related risk factors based on bedside data and produces outcomes data based on severity of complications. DESIGN: Cohort study. SETTING: Perioperative data related to all adult surgical procedures in a tertiary referral centre in Finland for 3 years (2016-2018) were included in the study. Complications were recorded according to a modified Clavien-Dindo classification, and the preoperative risk factors were compiled based on the literature and coded as numerical measures. The associations of preoperative risk factors with postoperative complications were analysed using the χ2 test or Fisher's exact test. RESULTS: In total, 19 158 operations were performed between 2016 and 2018. Data on complications (Clavien 0-9) were recorded for 4529 surgical patients (23.6%), and 779 complications were reported (Clavien 1-9), leading to an overall complication rate of 17.2%. Of these, 4.6% were graded as major (Clavien 4-7). Patient-related risk factors with the strongest association with complications were growing American Society of Anesthesiologists Physical Status Classification System score (p<0.001), growing Charlson Index (p<0.001), poor nutritional status (Nutritional Risk Screening 2002), p=0.041) and urgency of surgery (p<0.001). CONCLUSIONS: We describe an inexpensive hospital-wide surgical complication monitoring system that can produce valid numerical data for monitoring risk-adjusted surgical quality. The results showed that only a few patient-related risk factors were sufficient to account for the case mix.
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Hospitales , Complicaciones Posoperatorias , Adulto , Estudios de Cohortes , Humanos , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/etiología , Factores de RiesgoRESUMEN
OBJECTIVE: To study if patient-related factors are associated with patient-evaluated quality of care in surgery. To examine if there is an association with postoperative complications and patient-evaluated low quality of care. DESIGN: A correlation cross-sectional study, in addition, a phone call interview at 30 days postoperatively to examine complications. SETTING: The data on patients admitted for non-cardiac general and orthopaedic surgery at a central hospital in Southwestern Finland were collected in two phases during an 8-month period. PARTICIPANTS: 436 consecutive consenting and eligible in-ward non-cardiac general surgery and orthopaedic surgery adult patients. Ambulatory, paediatric and memory disorder patients were excluded. 378 patients completed the questionnaire (Good Nursing Care Scale for Patients (GNCS-P)). METHODS: Perceived quality of care was examined by the GNCS-P questionnaire. Patient-related factors were obtained from electronic patient records and questionnaire. A telephone interview related to postdischarge complications was conducted 30 days after discharge. MAIN OUTCOME MEASURES: Patient evaluation of quality of care at discharge, its association with patient-related factors and patient-reported postdischarge complications. RESULTS: The overall quality was evaluated high or very high by the patients. The lowest overall quality of care rate was assessed by surgical patients living alone (p=0.0088) and patients who evaluated their state of health moderate or poor (p=0.0047). Surgical patients reporting postoperative complications after discharge evaluated lower overall quality of care (p=0.0105) than patients with no complications. CONCLUSION: Patient demographic factors do not seem to influence the perceptions of the quality of care. Instead, subjective state of health and living conditions (living alone) may have an influence on the patient experience of quality of care. The perceived quality of care in healthcare staff technical and communication skills may have an association with reported postoperative complications.
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Cuidados Posteriores , Alta del Paciente , Adulto , Niño , Estudios Transversales , Finlandia , Humanos , Complicaciones Posoperatorias/epidemiologíaRESUMEN
Efficient re-epithelialization of skin lesions is dependent on paracrine support from connective tissue fibroblasts. In deep skin defects, the supporting growth factor incentive is lacking. Current methods of keratinocyte transplantation with compromised attachment, spread, and cell proliferation warrant improvement and refinement. We describe here how human keratinocytes can be stimulated by matrix-embedded factors from a novel process of fibroblast activation: nemosis. Interestingly, the unique set of mediators released in this process also plays a key role in normal wound healing. To develop a system for targeted delivery of nemosis-derived paracrine effectors, herein designated as Finectra, we combined them with fibrin to establish a controlled-release gel. Keratinocytes seeded to cover this active matrix showed better adherence, outgrowth, and viability than did cells on control matrix. The matrix incorporating Finectra supported viability of both primary keratinocytes and green fluorescent protein (GFP)-labeled HaCaT cells, as evaluated by MTT assay and persistence of GFP-fluorescence. The fibrin-Finectra matrix promoted migration of keratinocytes to cover a larger area on the matrix, suggesting better wound coverage on transplantation. An inhibitor of EGFR/c-Met receptor tyrosine kinases abolished keratinocyte responses to fibrin-Finectra matrix. This matrix can thus deliver biologically relevant synergistic stimuli to keratinocytes and hasten re-epithelialization.