Novel easily separable core-shell Fe3O4/PVP/ZIF-8 nanostructure adsorbent: optimization of phosphorus removal from Fosfomycin pharmaceutical wastewater.

A new easily separable core-shell Fe3O4/PVP/ZIF-8 nanostructure adsorbent was synthesized and then examined for removal of Fosfomycin antibiotic from synthetic pharmaceutical wastewater. The removal process of Fosfomycin was expressed through testing the total phosphorus (TP). A response surface model (RSM) for Fosfomycin adsorption (as mg-P L-1) was used by carrying out the experiments using a central composite design. The adsorption model showed that Fosfomycin adsorption is directly proportional to core-shell Fe3O4/PVP/ZIF-8 nanostructure adsorbent dosage and time, and indirectly to initial Fosfomycin concentration. The removal increased by decreasing the pH to 2. The Fosfomycin removal was done at room temperature under an orbital agitation speed of 250 rpm. The adsorption capacity of core-shell Fe3O4/PVP/ZIF-8 nanostructure adsorbent reached around 1200 mg-P g-1, which is significantly higher than other MOF adsorbents reported in the literature. The maximum Langmuir adsorption capacity of the adsorbent for Fosfomycin was 126.58 mg g-1 and Fosfomycin adsorption behavior followed the Freundlich isotherm (R 2 = 0.9505) in the present study. The kinetics was best fitted by the pseudo-second-order model (R 2 = 0.9764). The RSM model was used for the adsorption process in different target modes.

QCM-Based MgFe2O4@CaAlg Nanocomposite as a Fast Response Nanosensor for Real-Time Detection of Methylene Blue Dye.

Methylene blue (MB) dye is a common colorant used in numerous industries, particularly the textile industry. When methylene blue is discharged into water bodies without being properly treated, it may seriously damage aquatic and human life. As a result, a variety of methods have been established to remove dyes from aqueous systems. Thanks to their distinguishing features e.g., rapid responsiveness, cost-effectiveness, potential selectivity, portability, and simplicity, the electrochemical methods provided promising techniques. Considering these aspects, a novel quartz crystal microbalance nanosensors based on green synthesized magnesium ferrite nanoparticles (QCM-Based MgFe2O4 NPs) and magnesium ferrite nanoparticles coated alginate hydrogel nanocomposite (QCM-Based MgFe2O4@CaAlg NCs) were designed for real-time detection of high concentrations of MB dye in the aqueous streams at different temperatures. The characterization results of MgFe2O4 NPs and MgFe2O4@CaAlg NCs showed that the MgFe2O4 NPs have synthesized in good crystallinity, spherical shape, and successfully coated by the alginate hydrogel. The performance of the designed QCM-Based MgFe2O4 NPs and MgFe2O4@CaAlg NCs nanosensors were examined by the QCM technique, where the developed nanosensors showed great potential for dealing with continuous feed, very small volumes, high concentrations of MB, and providing an instantaneous response. In addition, the alginate coating offered more significant attributes to MgFe2O4 NPs and enhanced the sensor work toward MB monitoring. The sensitivity of designed nanosensors was evaluated at different MB concentrations (100 mg/L, 400 mg/L, and 800 mg/L), and temperatures (25 °C, 35 °C, and 45 °C). Where a real-time detection of 400 mg/L MB was achieved using the developed sensing platforms at different temperatures within an effective time of about 5 min. The results revealed that increasing the temperature from 25 °C to 45 °C has improved the detection of MB using the MgFe2O4@CaAlg NCs nanosensor and the MgFe2O4@CaAlg NCs nanosensor exhibited high sensitivity for different MB concentrations with more efficiency than the MgFe2O4 NPs nanosensor.

Design of a Novel Nanosensors Based on Green Synthesized CoFe2O4/Ca-Alginate Nanocomposite-Coated QCM for Rapid Detection of Pb(II) Ions.

Pb(II) is a significant contaminant that is known to have negative effects on both humans and animals. Recent industrial operations have exacerbated these consequences, and their release of several contaminants, including lead ions, has drawn attention to the potential effects on human health. Therefore, there is a lot of interest in the rapid, accurate, and selective detection of lead ions in various environmental samples. Sensors-based nanomaterials are a significant class among the many tools and methods developed and applied for such purposes. Therefore, a novel green synthesized cobalt ferrite (CoFe2O4) nanoparticles and functionalized CoFe2O4/Ca-alginate nanocomposite was designed and successfully synthesized for the fabrication of nanoparticles and nanocomposite-coated quartz crystal microbalance (QCM) nanosensors to detect the low concentrations of Pb(II) ions in the aqueous solutions at different temperatures. The structural and morphological properties of synthesized nanoparticles and nanocomposite were characterized using different tools such as X-ray diffraction (XRD), N2 adsorption-desorption isotherm, dynamic light scattering (DLS), zeta potential analyzer (ζ-potential), atomic force microscopy (AFM), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and energy-dispersive X-ray spectroscopy (EDX). The QCM results revealed that the green synthesized CoFe2O4 nanoparticles and functionalized CoFe2O4/Ca-alginate nanocomposite-coated QCM nanosensors exhibited high sensitivity, stability, and rapid detection of Pb(II) ions in the aqueous solutions at different temperature. The lowest detection limit for Pb(II) ions in the aqueous solutions could reach 125 ng, which resulted in a frequency shift of 27.49 ± 0.81, 23.63 ± 0.90, and 19.57 ± 0.86 Hz (Δf) for the QCM detector coated with green synthesized CoFe2O4 nanoparticles thin films, and 25.85 ± 0.85, 33.87 ± 0.73, and 6.87 ± 0.08 Hz (Δf) for the QCM detector coated with CoFe2O4/Ca-Alg nanocomposite thin films in a real-time of about 11, 13, and 13 min at 25 °C, 35 °C, and 45 °C, respectively. In addition, the resonance frequency change results showed the superiority of functionalized CoFe2O4/Ca-alginate nanocomposite coated QCM nanosensor over CoFe2O4 nanoparticles towards Pb(II) ions detecting, which attributed to the beneficial properties of alginate biopolymer.

Evaluation of Green-Synthesized Cuprospinel Nanoparticles as a Nanosensor for Detection of Low-Concentration Cd(II) Ion in the Aqueous Solutions by the Quartz Crystal Microbalance Method.

Cd(II) heavy metal is an extremely dangerous hazardous material for both humans and the environment. Its high toxicity is the reason behind the examination of new techniques for detecting very small concentrations of Cd(II). Recently, Quartz Crystal Microbalance (QCM) has been one of the techniques that have been widely used to detect trace heavy metal ions in solutions. It is a simple, inexpensive, portable, and sensitive gravimetric sensor due to its quality sensitivity lowest to nanograms. In this work, Cuprospinel nanoparticles were synthesized through the green synthesis approach using Psidium guajava L. leaf extract as a reducing agent, which is the first scientific description to report the preparation of these nanoparticles by this method. Subsequently, the synthesized nanoparticles were subjected to the characterization of their crystallinity, structure, and morphology by the XRD, N2 adsorption-desorption, zeta potential, DLS, AFM, SEM, and TEM analyzers. The prepared Cuprospinel nanoparticles were evaluated as a nanosensor for the detection of the very low concentration of Cd(II) ions in aqueous solutions using the QCM technique. The results of the characterization proved that the Cuprospinel nanoparticles have formed in the nanoscale with sub-spherical shapes and particles size ranging from 20 to 80 nm. The BET surface area and pore size analysis revealed that the synthesized Cuprospinel nanoparticles possess a surface area of 47.3 m2/g, an average pore size of 1.5 nm, and a micropore volume of 0.064 cc/g. The QCM results demonstrated the success of the Cuprospinel nanoparticles sensor in detecting the tiny amounts of Cd(II) ions in the aqueous solutions with concentrations reaching about 3.6 ng/L.

The Integrative Effects of Biochar and ZnO Nanoparticles for Enhancing Rice Productivity and Water Use Efficiency under Irrigation Deficit Conditions.

Water stress is considered one of the most environmental hazards that threaten agricultural productivity. Therefore, two field experiments were conducted to investigate the impact of biochar (6 t ha-1 as soil amendment), ZnO NPs (50 mg L-1 as foliar application), and their combination on growth, yield, and water use efficiency (WUE) of rice grown under four irrigation deficit treatments (i.e., irrigation every 3, 6, 9 and 12 d). The irrigation every 3 d was considered as the control in the current study. For this purpose, biochar was prepared through the pyrolysis of corn stalk and rice husk at 350 °C for 3 h, while sonochemical combined with the precipitation method was used to prepare zinc oxide nanoparticles (ZnO NPs) from zinc acetate. The morphological structures of the produced biochar and ZnO NPs were characterized using X-ray diffraction (XRD), N2 gas adsorption-desorption, scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The results exhibited that the combination of biochar alongside ZnO NPs resulted in a positive significant effect on the physiological traits such as chlorophyll content, relative water content, plant height, and leaf area index as well as yield-associated components (i.e., number of panicles m-2, number of filled grain per panicle, 1000-grain weight), and biological and grain yield ha-1 when rice plants were irrigated every 9 days without a significant difference with those obtained from the control treatment (irrigation every 3 d). In conclusion, the combination of biochar and ZnO NPs could be recommended as an optimal approach to maximize both grain yield ha-1 and WUE of rice.

Behavior of Silica Nanoparticles Synthesized from Rice Husk Ash by the Sol-Gel Method as a Photocatalytic and Antibacterial Agent.

Silica nanoparticles (SiO2 NPs) are one of the most well-studied inorganic nanoparticles for many applications. They offer the advantages of tunable size, biocompatibility, porous structure, and larger surface area. Thus, in this study, a high yield of SiO2 NPs was produced via the chemical treatment of rice husk ash by the sol-gel method. Characteristics of the prepared SiO2 NPs were validated using different characterization techniques. Accordingly, the phase, chemical composition, morphological, and spectroscopic properties of the prepared sample were studied. The average particle size of the SiO2 NPs was found to be approximately 60-80 nm and the surface area was 78.52 m²/g. The prepared SiO2 NPs were examined as photocatalysts for the degradation of methyl orange (MO) dye under UV irradiation. It was found that the intensity of the characteristic absorption band of MO decreased gradually with exposure time increasing, which means the successful photodegradation of MO by SiO2 NPs. Moreover, the antibacterial activity of obtained SiO2 NPs was investigated by counting the coliform bacteria in the surface water using the most probable number (MPN) index method. The results revealed that the MPN of coliform bacteria untreated and treated by SiO2 NPs was estimated to be 170 CFU/100 mL and 10 CFU/100 mL, respectively, resulting in bacterial growth inhibition of 94.12%.

Bacteriostatic impact of nanoscale zero-valent iron against pathogenic bacteria in the municipal wastewater.

Nanoscale zero-valent iron particles were investigated as an antibacterial agent against two Gram-positive bacteria; Staphylococcus aureus NRRL B-313 (S. aureus), Bacillus subtilus NRC (B. subtilus), and two Gram-negative bacteria; Escherichia coli NRC B-3703 (E. coli), Pseudomonas aeruginosa NRC B-32 (Ps. aeruginosa). The characterization of synthesized nZVI particles was obtained by XRD, SEM, EDX, and TG analyses. The results demonstrated that the nZVI particles have a spherical shape, mean crystalline size of 44.43 nm, and exhibited a good chemical and thermal stability performance under different physical conditions. The bacterial suspensions were subjected to the treatment using nZVI particle suspensions with a concentration of 10 mg/mL. The minimum inhibitory concentration of nZVI particles was determined using the well diffusion assay method and found to be 15, 10, 10, and 5 mg for the following four strains; S. aureus, B. subtilus, E. coli, and Ps. aeruginosa, respectively. The biological treatment results of municipal wastewater using nZVI particles revealed that the counts of total bacteria, total coliform, fecal coliform, S. aureus, fecal Streptococcus, and E. coli were decreased to 44.29%, 51.76%, 90.95%, 46.67%, 33.33%, and 93.89%, respectively, while the Ps. aeruginosa not detected in the wastewater sample. The enhanced inactivation performance of nZVI nanoparticles was mainly attributed to the reactive oxygen species (ROS) production, releasing of iron corrosion products like Fe2+/Fe3+ ions, and direct friction of nZVI particles with bacterial cells membranes. In addition, the nZVI particles presented a striking disinfection behavior in comparison with other widespread disinfection technologies such as chlorination. Accordingly, the obtained results introduce the nZVI particles as a promising disinfection technology.

Ways to harness the built environment of ambulatory cancer facilities for comprehensive patient support: A review of the literature.

OBJECTIVE: To review patient experiences of the architectural elements conducive to a supportive or healing-promoting environment in the context of ambulatory oncology care. DESIGN: A comprehensive review of original peer-reviewed qualitative studies conducted to reveal the meaning and significance of patient experience in this context was undertaken. DATA SOURCES: Studies were identified through electronic databases including Ovid MEDLINE, CINAHL, PubMed and Embase. No time limit was applied and language was restricted to English. REVIEW METHODS: The generated records were screened at the titles and abstracts level by the first reviewer, with full text assessment conducted by both authors. Main themes were extracted in an excel file and a narrative synthesis strategy was used to systematically gather evidence and explain the findings. The guidelines of the Centre for Reviews and Dissemination have been followed in the searching and reporting of the essential matters relevant to this review. RESULTS: Eleven original studies were selected; in addition to these, fourteen other studies that did not fully meet the selection criteria, however held important information relevant to the scope of the review, were considered to expand the discussion with relevant information to ambulatory cancer facilities. The findings of these studies were synthesized into five major themes: stimulating and homely environments; flexibility and environmental enrichment; social support; complementary support and engagement; and physical and sensory support. CONCLUSION: The paper identified key architectural design qualities that have the potential to support treatment and empower patients, with particular reflection on patients undergoing intravenous anti-cancer treatment within ambulatory settings. It provides examples in which designing the built environment with people in mind and providing tailored solutions to meet their actual needs and preferences may help cancer patients cope with the emotional and physical challenges of the disease and its treatment and support a general experience of patient-centred care. A conceptual framework that articulates the principal constituents of a supportive environment is tentatively proposed, extending existing theoretical propositions to facilitate further investigation of this context.

Parkinsonism due to manganism in a welder.

A 33-year-old right-handed male presented complaining of a 2-year history of progressive cognitive slowing, rigidity, tremors, slowing of movements, and gait instability leading to falls. On examination, he had a Mini-Mental Status Examination (MMSE) score of 29, slowed saccadic eye pursuit, hypomimia, cogwheel rigidity, a 3- to 4-Hz tremor, and a "cock-walk" gait. His symptoms and signs were similar to idiopathic Parkinson's disease; however, he was young, inattention and forgetfulness occurred early in the course of the disorder, levodopa was unhelpful, and his gait was atypical. His work up for secondary causes of parkinsonism was negative, except for increased signal intensity on T1-weighted magnetic resonance image (MRI) in the bilateral basal ganglia. Typical etiologies for that finding were ruled-out, which led to further inquiries into the patient's lifestyle. He was a welder, and discussion with his employer revealed that he used a steel-manganese alloy, he often worked in a confined ship's hold, and he did not use a respiratory mask. Because manganese toxicity can produce increased T1-weighted signal intensities in the basal ganglia, the authors tested his serum and urine manganese, and both were elevated. This patient emphasizes the importance of a careful occupational history in persons presenting with atypical manifestations of a neurodegenerative disorder. It also lends support to the hypothesis that welding can produce enough exposure to manganese to produce neurologic impairment.