Cognitive performance of post-covid patients in mild, moderate, and severe clinical situations.

BACKGROUND: Studying individuals with varying symptoms, from mild to severe, can provide valuable insights into the spectrum of cognitive outcomes after COVID-19. We investigated the cognitive performance of adults who recovered from the novel coronavirus disease (COVID-19) without prior cognitive complaints, considering mild (not hospitalized), moderate (ward), and severe (intensive care unit) symptoms. METHODS: This cross-sectional study included 302 patients who recovered from COVID-19 (mild, n = 102; moderate, n = 102; severe, n = 98). We assessed intellectual quotient (IQ), attention, memory, processing speed, visual-constructive ability, as well as symptoms of depression, anxiety, and stress, at least eighteen months after infection. The mean length of hospitalization was Mdays=8.2 (SD = 3.9) and Mdays=14.4 (SD = 8.2) in the moderate and severe groups, respectively. RESULTS: Cognitive difficulties were present in all three groups: mild (n = 12, 11.7%), moderate (n = 40, 39.2%), and severe (n = 48, 48.9%). Using Multinomial Logistic Regression and considering the odds ratio, our results indicated that a one-point increase in sustained attention, visual memory, and working memory might decrease the odds of being categorized in the severe group by 20%, 24%, and 77%, respectively, compared to the mild group. CONCLUSIONS: Our findings provide empirical evidence regarding the long-term cognitive effects of COVID-19, particularly in individuals experiencing severe manifestations of the disease. We also highlighted the need for a comprehensive, multidimensional approach in rehabilitation programs to address the enduring cognitive impacts of COVID-19.

Personality Characteristics of Children and Adolescents with Anxiety Disorder from a Maternal Perspective: A Brief Report.

The present study assessed the personality characteristics of children and adolescents with anxiety disorder from a maternal perspective. A total of 48 children and adolescents aged between 8 and 17 years participated in this study, which was organized as follows: a clinical group (24 children and adolescents with anxiety disorders and their respective mothers) and a control group (24 children and adolescents without psychiatric diagnosis and their mothers). The participants were submitted to the WASI, CBCL, MASC-2, and EPQ-J tests and their mothers to the SRQ-20 and PIC-2 tests. The results showed higher rates of internalizing symptoms in the clinical group. In addition, patients showed less interest in hobbies, less adherence to social organizations, impairment in social activities, and commitment to school performance compared to the control group. There was a positive correlation between the mothers' symptoms and each of the following PIC-2 domains: somatic concern (p < 0.01) and psychological discomfort (p < 0.01). In conclusion, youths with AD showed a withdrawn and reserved personality profile, involving distrust of impulses and avoidance of interactions with peers. Furthermore, psychoemotional problems of mothers adversely influenced the perception followed by anxiety and adjustment characteristics. More studies are needed to assess the maternal personality in youths with anxiety.

Cognitive Processes and Legal Capacity in Patients With Bipolar Disorder: A Brief Research Report.

The current study verified the association between cognitive process such as attention, executive functioning, and legal capacity in patients with bipolar disorder (BD). The sample consisted of 72 participants, assorted to episodic patients (n = 21), euthymic patients (n = 22), and healthy controls (HCs) (n = 29). We used the following neuropsychological measures: subtests of the Wechsler Abbreviated Intelligence Scale (WASI): vocabulary and matrix reasoning; Continuous Performance Test (CPT); Five Digit Test (FDT); and Rey-Osterrieth Complex Figure (ROCF). Euthymic patients expressed slower processing speed (FDT) compared to HC. They tended to make more errors with slightly worse discrimination, suggesting more impulsiveness (CPT, p < 0.01). On the contrary, episodic patients showed worse discrimination, committed more omissions, were more inconsistent with regard to response speed (CPT-3, p < 0.01), showed more difficulties in organizing their actions (ROCF: copy, p = 0.03), and were more rigid (FDT: flexibility, p = 0.03). The results suggest that bipolar patients in episode express more cognitive impairments that can compromise the quality of legal capacity. These results highlight the need for more protective support for episodic BD patients regarding legal capacity.

Differential Diagnosis Findings Between Alzheimer's Disease and Major Depressive Disorder: A Review.

Background: Differentiating diagnosis between Alzheimer's disease and major depressive disorder in the elderly is a great clinical challenge. This study aimed to identify the establishment of differential diagnosis protocols between Alzheimer's disease and major depressive disorder. Methods: We searched studies in the Ovid MEDLINE, EMBASE, PsycINFO, and Web of Science databases between 2009 and 2019. A total of 155 references were found for searching relevant articles using Boolean search. After exclusion of redundancies and assessing of title, abstract, and full text for eligibility, 11 articles were selected. The total sample size was 1077 distributed in 8 different countries. Results: Significant results were found for differential diagnosis between Alzheimer's disease and major depressive disorder, such as overall mental status, episodic memory, visuospatial construction, delayed recognition task, semantic verbal fluency, visual task in short-term memory, atrophy of the hippocampus, cortical activation in specific tasks, and cerebrospinal fluid biomarkers. Conclusion: These findings are good pathways for discriminating Alzheimer's disease from major depression in the elderly.

Psychological demands of health professionals in the initial phase of the COVID-19 pandemic.

Recent literature emphasizes how the specific stressors of the COVID-19 outbreak affect the general population and frontline professionals, including those conducting support or backup activities in health units, which can lead to vicarious traumatization. Vicarious traumatization has been used to describe negative emotional reactions in mental health professionals who assist or treat victims of traumatic events. Thus, the aim of this article is to report the actions used in the face of the psychological demands of professionals in a hospital, who were not on the frontline of COVID-19. We collected their sociodemographic information and checked the psychological impact using the depression, anxiety, and stress scale (DASS-21), which was followed by a psychoeducational program (topics related to COVID-19 control and prevention), and individual psychological care for the most severe cases. A total of 118 professionals participated in this study; they were between 20 and 67 years old. Mild to moderate anxiety was observed in 36.5% of the medical teams, 83.3% of the administrative staff, and 65.7% of general service workers, while stress symptoms were observed in 80.2%, 83.3%, and 59.9%, respectively. Depressive symptoms (35.3%) were more frequent in general service workers. The medical teams reported the benefits of primary psychological care, while the other professionals demanded more institutional support services related to the prevention and use of personal protective equipment. This study highlights relevant psychological demands that have repercussions on the daily lives of professionals. The psychoeducational program was considered positive regarding clarification actions. However, it was not perceived as effective in reducing fear, which may result from vicarious traumatization and requires other intervention modalities.

Exploratory study on the psychological impact of COVID-19 on the general Brazilian population.

The COVID-19 pandemic has become one of the main international concerns regarding its impact on mental health. The present study aims to investigate the prevalence of depression, anxiety, and stress symptoms, and behavioral aspects amidst the COVID-19 pandemic in a Brazilian population. An online survey was administered from May 22 to June 5, 2020 using a questionnaire comprising of sociodemographic information, the Depression, Anxiety, and Stress Scale (DASS-21), and the Coping Strategies Inventory. Participants comprised 3,000 people from Brazil's 26 states and the Federal District, with an average age of 39.8 years, women (83%), married (50.6%), graduates (70.1%) and employees (46.7%). Some contracted the virus (6.4%) and had dead friends or relatives (22.7%). There was more consumption of drugs, tobacco, medication, and food (40.8%). Almost half of participants expressed symptoms of depression (46.4%), anxiety (39.7%), and stress (42.2%). These were higher in women, people without children, students, patients with chronic diseases, and people who had contact with others diagnosed with COVID-19. The existence of a group more vulnerable to situations with a high stress burden requires greater attention regarding mental health during and after the pandemic. That said, it should be emphasized that these findings are preliminary and portray a moment still being faced by many people amid the pandemic and quarantine measures. Therefore, we understand that the magnitude of the impacts on mental health will only be more specific with continuous studies after total relaxation of the quarantine.

Psychological evaluation of children victims of sexual abuse: development of a protocol.

Sexual abuse (SA) is associated with significant psychological problems in childhood, making it increasingly important to develop evaluation protocols. This study examined clinical aspects and cognitive measures of 49 children (24 with SA history and 25 controls). It employed a SA assessment questionnaire, clinical evaluations of posttraumatic stress disorder, risk indicators and neuropsychological tests in order to elaborate a specific forensic psychological evaluation protocol for this population. Conflicting couples (80%), separated parents (68%) and parents' alcohol/drug abuse (76%) were revealed as major risk factors. Fathers represented the primary perpetrator (24%). The main cognitive complaint was difficulty concentrating. Regarding the association between clinical and cognitive variables, it was observed that children who were anxious or referred to having fear, difficulties with operational memory and difficulty sleeping, had more trouble performing tasks that required attention and memory (operational, immediate and late). Children with SA history demonstrated inferior performance in visual attention/task switching and memory; with an emphasis in the loss of set in the Wisconsin test. The findings suggest the possibility of a primary attention deficit in children with SA history, possibly influencing the performance of other cognitive functions.

Psychological demands of health professionals in the initial phase of the COVID-19 pandemic

Abstract Recent literature emphasizes how the specific stressors of the COVID-19 outbreak affect the general population and frontline professionals, including those conducting support or backup activities in health units, which can lead to vicarious traumatization. Vicarious traumatization has been used to describe negative emotional reactions in mental health professionals who assist or treat victims of traumatic events. Thus, the aim of this article is to report the actions used in the face of the psychological demands of professionals in a hospital, who were not on the frontline of COVID-19. We collected their sociodemographic information and checked the psychological impact using the depression, anxiety, and stress scale (DASS-21), which was followed by a psychoeducational program (topics related to COVID-19 control and prevention), and individual psychological care for the most severe cases. A total of 118 professionals participated in this study; they were between 20 and 67 years old. Mild to moderate anxiety was observed in 36.5% of the medical teams, 83.3% of the administrative staff, and 65.7% of general service workers, while stress symptoms were observed in 80.2%, 83.3%, and 59.9%, respectively. Depressive symptoms (35.3%) were more frequent in general service workers. The medical teams reported the benefits of primary psychological care, while the other professionals demanded more institutional support services related to the prevention and use of personal protective equipment. This study highlights relevant psychological demands that have repercussions on the daily lives of professionals. The psychoeducational program was considered positive regarding clarification actions. However, it was not perceived as effective in reducing fear, which may result from vicarious traumatization and requires other intervention modalities.

[Cognitive rehabilitation in Alzheimer's disease patients: multidisciplinary team report]. / Reabilitação cognitiva em pacientes com doença de Alzheimer: Relato de trabalho em equipe multidisciplinar.

OBJECTIVE: This study aims to show preliminary results of the 'combined treatment' (acetylcholinesterase inhibitor + cognitive training) on a group of mild Alzheimer's disease (AD) patients, followed-up for 7 months. METHODS: Six mild AD patients, diagnosed according to ICD-10 and NINCDS-ADRDA criteria, were included on a open trial with Rivastigmine, 6-12 mg/day, for 2 months, followed by a weekly cognitive rehabilitation group, for 5 months. Caregivers were submitted to a weekly group of counseling and support for 5 months. RESULTS: Stabilization or mild improvement of patients' cognitive and activities of daily living deficits were found, besides reduction of patients and caregivers' depressive and anxiety levels. CONCLUSION: The 'combined treatment' can help on the stabilization or result on a mild improvement of AD patients' cognitive and functional deficits. Support and counseling interventions can reduce the levels of caregivers' psychiatric symptoms.

Forensic neuropsychological assessment: clinical case of depression and working incapacity / Avaliação neuropsicológica forense: caso clínico de depressão e incapacidade para o trabalho

Issues related to mental health in relation to court matters have increasingly required the participation of the psychologist. We present the use of forensic neuropsychological assessment in a case of retirement reversal. Incapacity was attested due to disability resulting from depression of a 35-year-old attorney, and the case was forwarded from the courts to the Forensic Psychiatry and Psychology Unit at the USP Clinical Hospital. A clinical interview and application of cognitive tests was conducted. Despite the depression, significant cognitive losses that would prevent return to his professional assignments were not detected. The neuropsychological assessment has been shown to be an important tool in the forensic context, as it assists with diagnostic value for clarification of functional aspects in the various psychopathological areas in terms of disabilities or potentialities.

Assuntos relacionados à saúde mental na corte vêm demandando crescente participação de psicólogos. Sob este mote, apresentamos uma aplicação de um assessment neuropsicológico em um caso de reversão de aposentadoria por invalidez. Trata-se do caso de um juiz de 35 anos, que chegou à nossa Unidade de Tratamento Forense Psicológico e Psiquiátrico, no Hospital das Clínicas da Universidade de São Paulo. Para suprir a demanda, inicialmente conduzimos uma entrevista clínica e, em seguida, aplicamos uma bateria neuropsicológica, a partir da qual foi revelada a inexistência de limitações do desempenho cognitivo, as quais recomendariam a reafirmação do afastamento do profissional. Tal como revelado, o uso adequado do assessment neuropsicológico mostra-se uma importante ferramenta em contexto forense, auxiliando o esclarecimento de aspectos funcionais do diagnóstico, em vários contextos psicopatológicos.

Forensic neuropsychological assessment: a review of its scope

Issues related to the field of mental health and justice require a multifactorial understanding of the possible causes of such issues. Objective To conduct an integrative literature review of controlled studies describing forensic neuropsychological assessment. Methods The articles were compiled and analyzed in two phases: 1) first, we retrieved all papers in PubMed by the keywords “Forensic Neuropsychology” and generated a growth curve for the subject and a cluster-based thematic distribution of publications. 2) We then conducted a curated analysis of all relevant papers indexed in Medline, PubMed and ISI, between 2000 and 2012. Results The evolution of the field during the last 15 years reveals an unstable growth pattern and three main thematic clusters. In terms of our curated analysis, a total of 390 articles were pre-selected, resulting in the selection of 44 fully-relevant studies, which comprise four main categories: cognitive damage in forensic psychiatric patients; imitation of cognitive damage; civil capacity, penal liability and violence risk; and validation of neuropsychological assessment tools. Discussion Two aspects appeared as the most relevant in this study: growth in the use of neuropsychological assessment as a diagnostic tool in the forensic context; and the necessity to enhance conformity in assessments...

Assessment of a penitentiary relapse prevention program / Avaliação de um programa de prevenção à reincidência prisional

Ten structured meetings of cognitive-behavioral therapy for relapse prevention were applied with prison inmates. The project had the participation of 28 subjects, divided into a work group and control group (15 and 13 subjects respectively), who were evaluated before and after the intervention. There was no significant difference in reoffending. Despite this, the program reduced the fear of negative evaluation (especially among non-reoffenders) and the Social Stress and Escape Scale score. After one year, reoffenders had lower scores in the Social Stress and Escape Scale and a tendency to have higher scores in the Dysfunctional Attitude Scale...

Dez sessões de terapia cognitivo-comportamental visando prevenir à reincidência penitenciária foram desenvolvidas para a população prisional. O projeto teve a participação de 28 sujeitos, divididos em grupo de trabalho e grupo controle (15 e 13 sujeitos, respectivamente), que foram avaliados antes e depois da intervenção. Não houve diferença significativa na reincidência. Apesar disto, a terapia cognitivo-comportamental reduziu o medo de avaliação negativa (principalmente entre os não reincidentes) e o escore na Escala de Estresse e Fuga Social. Após um ano, os reincidentes apresentaram resultados mais baixos na Escala de Estresse e Fuga Social e uma tendência a apresentar escores mais elevados na Escala de Atitudes Disfuncionais...

Dados demográficos, psicológicos e comportamentais de crianças e adolescentes vítimas de abuso sexual / Demographic, psychological and behavioral characteristics of child and adolescent victims of sexual abuse

CONTEXTO: A relação entre transtorno mental e histórico de abuso sexual é frequentemente observada na prática clínica e relatada na literatura. OBJETIVO: Descrever os dados demográficos e os aspectos emocionais e comportamentais em crianças e adolescentes vítimas de abuso sexual. MÉTODO: 205 crianças e adolescentes com idade entre 6 e 14 anos, sendo 130 meninas (9,6 ± 3,4 anos) e 75 meninos (7,2 ± 2,9 anos) vítimas de abuso sexual passaram por avaliação psicológica e psiquiátrica individual no período de 2005 a 2009. As variáveis estudadas foram: gênero, faixa etária, grau de relação da vítima com o perpetrador, aspectos psicológicos, dados psiquiátricos, aspectos comportamentais e afetivo-emocionais (culpa, vergonha, medo, insegurança, percepção da figura masculina e feminina e de si em relação ao ambiente). RESULTADOS: As meninas são as maiores vítimas (63,4 por cento). A faixa etária de maior risco para as meninas é entre 7 e 10 anos de idade (48,5 por cento), enquanto para os meninos é de 3 a 6 anos (54,6 por cento). Os pais são os maiores perpetradores do abuso sexual (38 por cento), seguidos do padrasto (29 por cento). Meninos e meninas expressaram elevada frequência para depressão e transtorno de estresse pós-traumático (TEPT). As meninas expressam comportamento mais erotizado, enquanto os meninos ficam mais isolados. CONCLUSÃO: Este estudo permitiu identificar uma parcela relevante de aspectos psicológicos, psiquiátricos e comportamentais, os quais podem afetar de forma impactante o desenvolvimento emocional de crianças e adolescentes.

BACKGROUND: There is a well known relationship between sexual abuse in children and mental health disorders, which is seen both in clinical practice as in the scientific literature. OBJECTIVE: To describe demographic profile as well as behavioral and emotional features of a cohort of children and adolescents sexually abused. MÉTODO: 205 children and adolescent, ranging from 6 to 14 years old, 130 girls (age 9.6 ± 3.4 yo) and 75 boys (age 7.2 ± 2.9 yo) were evaluated due to being victims of sexual abuse between the years 2005 and 2009. Gender, age, relationship with the perpetrator, psychological and psychiatric symptoms, behavioral and affective-emotional features (blame, shame, fearfulness, male and female figures image and self perception) were all properly evaluated. RESULTS: Girls were the main victims (63.4 percent). The riskier age ranging from 7 to 10 yo (48.5 percent) among then, and from 3 to 6 yo (54.6 percent) for the boys. Fathers are the major perpetrators (38 percent) followed by step-fathers (29 percent). Boys and girls show high risk for depression and Post-traumatic stress disorder (PTSD) symptoms. Girls tend to be more sexualized whilst boys tend to isolate themselves. DISCUSSION: This research allowed to identify an important set of psychological, psychiatric and behavioral characteristics that affect the normal emotional development of children and adolescents.

Prevalence of mental disorders among sexual offenders and non-sexual offenders / Prevalência de transtornos mentais entre agressores sexuais e não sexuais

OBJECTIVE: To evaluate the prevalence of mental disorders in convicted sex offenders admitted to the Psychiatric Custody and Treatment Hospital (Forensic Psychiatric Facility). METHOD: 89 patient records of males admitted from March 2005 to August 2006 were analyzed. The analysis included evaluation of two study groups: Group I comprised subjects who had committed sex offenses (sexual offenders) while Group II contained subjects convicted for other crimes (non-sexual offenders). Variables studied were: age bracket, years of schooling, marital status, skin color, place of birth, previous psychiatric admissions and psychiatric diagnosis. RESULTS: Mental retardation and personality disorders were the mainly diagnoses in Group I (sexual offenders) (61,76 percent and 29,41 percent respectively). In the other hand, schizophrenic subjects predominated in Group II (non-sexual offenders) (82,93 percent). CONCLUSION: Different from international data, we have found low prevalence of personality disorders among Brazilian forensic population and we believe that it's due to a distinguishing characteristic of the Brazilian legal system, which does not consider personality disorder a mental disease, thus, not prompting these patients to civil commitment.

OBJETIVO: Avaliar a prevalência de transtornos mentais em pacientes em cumprimento de medida de segurança por crimes de natureza sexual e não sexual. MÉTODO: Foram analisados 89 prontuários de pacientes do sexo masculino internados no período de março de 2005 a agosto de 2006. A análise consistiu na avaliação de dois grupos de estudo assim divididos: Grupo I, composto de sujeitos que cometeram crimes sexuais, e Grupo II, formado por sujeitos que foram condenados por outros crimes que não de natureza sexual. As variáveis analisadas foram: idade, grau de escolaridade, estado civil, cútis, naturalidade, internações psiquiátricas anteriores e diagnóstico psiquiátrico. RESULTADOS: Entre os sujeitos do Grupo I (condenados por crimes sexuais), observou-se maior prevalência de diagnóstico de retardo mental (61,76 por cento) e transtorno de personalidade (29,41 por cento). Já no Grupo II (condenados por crimes de outra natureza que não sexual), houve predominância do diagnóstico de esquizofrenia (82,93 por cento). CONCLUSÃO: Diferentemente do encontrado na literatura internacional, em nosso meio observou-se baixo índice de transtorno de personalidade entre os sujeitos estudados, o que pode ser justificado pelo fato de o sistema penal brasileiro considerar tal diagnóstico apenas como perturbação da saúde mental, não acarretando em medida de segurança ou internação psiquiátrica.

Cognitive rehabilitation combined with drug treatment in Alzheimer's disease patients: a pilot study.

OBJECTIVE: To study the efficacy of cognitive rehabilitation combined with acetylcholinesterase inhibitor (AChE-I) treatment in patients with mild Alzheimer's disease and their relatives. METHOD: Thirteen patients with mild Alzheimer's disease treated with rivastigmine 6-12 mg/day for more than two months started cognitive rehabilitation training. Before and after the cognitive rehabilitation training patients were assessed through cognitive tests, activities of daily living scale, neuropsychological battery and scales to evaluate caregivers' depressive and anxiety symptoms. Six patients were randomized to a combined treatment group (AChE-I plus cognitive rehabilitation and caregiver support) and seven patients to a control group (AChE-I only) and followed up for five months. RESULTS: Mini-Mental State Examination (MMSE) scores (p = 0.047) and backward digit span scores (p = 0.018) were significantly different between the groups on follow-up. The combined treatment group showed a better positive treatment effect on cognitive and neuropsychological tests applied to patients and reduction of psychiatric symptoms was observed in their caregivers (nonsignificant). CONCLUSION: Cognitive rehabilitation associated with AChE-I treatment can potentially be useful to stabilize or improve cognitive and functional performance of patients with mild Alzheimer's disease and can reduce caregivers' psychiatric symptoms.

Perfil psicológico e comportamental de agressores sexuais de crianças: [revisão] / Psychological and behavioral profile of sexual abusers of children: [review]

CONTEXTO: A prática de abuso sexual contra crianças é um fenômeno universal. Ela ocorre em todos os tempos e lugares e atinge todas as classes socioeconômicas. Enquanto a maioria dos estudos investiga as vítimas, os poucos estudos sobre agressores se concentram principalmente em dados demográficos. OBJETIVO: Apresentar revisão da literatura quanto à classificação de molestadores sexuais de crianças, de acordo com o perfil psicológico e comportamental. MÉTODOS: Revisão da literatura e discussão do material utilizado. RESULTADOS: Apresentação das principais classificações dos criminosos sexuais contra crianças, identificando as tipologias mais utilizadas com suas possíveis contribuições à psiquiatria e à psicologia forense. CONCLUSÃO: A utilização do perfil psicológico em crimes sexuais é de fundamental relevância no contexto médico-legal, mas ainda carece de bases científicas mais sólidas.

BACKGROUND: Sexual violence against children is a universal problem, occurring since ever, everywhere and regardless the socio-economic status. Whist most studies have been dedicated to the victim of such crime, there is little information regarding their perpetrators, which is largely limited to the description of demographic data. OBJECTIVE: Review the literature regarding children sexual aggressors according to psychological and behavioral profile. METHODS: Literature review and discussion. RESULTS: Presentation of the major classifications of offenders, pointing out the most widely used ones and the implications to forensic psychiatry and psychology. CONCLUSION: The psychological and behavioral profile use is very important for medico-legal practice, but still needs better scientific validation.

Prejuízos neurocognitivos na dependência alcoólica: um estudo de caso / Neurocognitive impairments in alcohol dependence: a case report

CONTEXTO: A alta prevalência de indivíduos dependentes de álcool estimula a realização de estudos que ampliem o entendimento de seus efeitos sobre o organismo. OBJETIVO: O objetivo deste estudo foi avaliar a preservação e prejuí­zo de funções neuropsicológicas em um caso de dependência alcoólica. Trata-se de estudo de caso de um alcoolista em tratamento medicamentoso no Hospital das Clínicas da Universidade de São Paulo, que declarava encontrar-se abstêmio desde o início do tratamento há cerca de um ano. MÉTODOS: Os instrumentos utilizados neste estudo foram entrevistas e testes neuropsicológicos (WAIS-III, Figura de Rey e WRAML-II). RESULTADOS: Os resultados das funções visuomotoras, praxia construtiva, memórias visual e verbal e capacidade de aprendizagem apresentaram graves prejuízos. O paciente teve um desempenho ligeiramente melhor, embora ainda rebaixado, em linguagem, aritmética e memória para sentenças curtas. A atenção imediata teve resultado dentro da normalidade, dado consistente com achados anteriores. O resultado no Subteste Semelhanças reforça evidências da capacidade de generalização em indivíduos dependentes de álcool. CONCLUSÃO: Conclui-se que os dados obtidos são consistentes com a literatura atual que apontam graves prejuízos na memória e funções visuomotoras paralelamente a manutenção da atenção e capacidade de generalização.

BACKGROUND: The high prevalence of alcohol dependence asks for a better comprehension of its effects on the organism. OBJECTIVE: The aim of this study was to evaluate prejudice and preservation of neuropsychological functions of alcohol dependence. It is presented a case report of a patient under drug treatment in Hospital das Clínicas da Universidade de São Paulo. The patient declared abstinence since the beginning of the treatment, about one year ago. METHODS: Interviews and neuropsycological tests (WAIS-III, Figure of Rey and WRAML-II). RESULTS: The results indicated serious damages in visuomotor functions, constructive praxia, visual and verbal memory and capacity of learning. The patient had a slightly better performance in language, arithmetic and memory for short sentences, even though still below averaged. The immediate attention had resulted normal, consistent with previous findings. The result in the Sub-test Similarities reinforces the generalization capacity of alcohol dependents. CONCLUSION: The data had been compatible with literature that points severe prejudice in memory and visuo-motor functions even with preserved attention and generalization habilities.

Reabilitaçäo cognitiva em pacientes com doença de Alzheimer: Relato de trabalho em equipe multidisciplinar / Cognitive rehabilitation in Alzheimer's disease patients: multidisciplinary team report

OBJETIVO: Apresentar resultados preliminares do 'tratamento combinado' (inibidor da acetilcolinesterase + treinamento cognitivo), em um grupo de pacientes com doença de Alzheimer (DA) leve, acompanhados por 7 meses. MÉTODO: Seis pacientes com diagnóstico de DA leve, de acordo com critérios diagnósticos da CID-10 e NINCDS-ADRDA, foram submetidos a ensaio clínico aberto com Rivastigmina, 6-12 mg/dia, por 2 meses, seguido por grupo de reabilitaçäo cognitiva semanal, por 5 meses. Os familiares/cuidadores foram atendidos em grupo semanal de suporte e aconselhamento, por 5 meses. RESULTADOS: Ao final do acompanhamento, houve: estabilizaçäo ou discreta melhora dos déficits cognitivos e das atividades de vida diária dos pacientes; estabilizaçäo ou reduçäo dos níveis de depressäo e ansiedade nos pacientes e familiares. CONCLUSÄO: O 'tratamento combinado' pode auxiliar na estabilizaçäo ou resultar em leve melhora dos déficits cognitivos e funcionais de pacientes com DA leve. As intervençöes de suporte e aconselhamento podem reduzir o nível de sintomas psiquiátricos de seus familiares. PALAVRAS-CHAVE: demência, doença de Alzheimer, inibidor da acetilcolinesterase, reabilitaçäo cognitiva, atividades de vida diária, cuidadores